Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

SedaLin Ingredients & Drug Interactions

by XYMOGEN

SedaLin label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking SedaLin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

SedaLin is a dietary supplement by XYMOGEN with 2 active ingredients. Its ingredients are commonly taken for anxiety and stress, sleep problems, digestive upset.Based on those ingredients, 351 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Magnolia officinalis. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against SedaLin by XYMOGEN

Ask about any prescription or over-the-counter medication and we check it for interactions with SedaLin by XYMOGEN — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of SedaLin by XYMOGEN

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Seditol” is listed as a grouped ingredient — the label gives one combined amount (730 mg) without saying how much of each component you get.

SedaLin contains two active ingredients: magnolia officinalis (magnolia bark extract) and Seditol, a proprietary blend. Magnolia has been used traditionally for relaxation and sleep support.

The product also includes several inactive ingredients — HPMC, magnesium stearate, stearic acid, microcrystalline cellulose, calcium silicate, and silica — which are the capsule and binding materials.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Magnolia's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support restful sleep.
  • We looked for evidence on: Anxiety, Stress, Insomnia, Sleep quality, Sleep onset.
  • The closest evidence on file: Magnolia is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Magnolia is rated "Insufficient Reliable Evidence To Rate" for Stress.

For magnolia, the evidence is mixed. It's rated possibly effective for gingivitis (gum inflammation), based on some clinical data.

For anxiety and hay fever (allergic rhinitis), the evidence isn't strong enough to rate — we simply don't have enough reliable studies. Dental plaque also lacks sufficient evidence.

Because Seditol is a proprietary blend, we don't have effectiveness ratings for it as a whole, and we couldn't check the Ziziphus spinosa extract.

The evidence, ingredient by ingredient Magnolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Magnolia is generally well tolerated when taken by mouth, though human safety data is limited overall. Topical use can cause contact dermatitis (skin irritation).

In clinical trials of combination products containing magnolia, a small number of participants reported side effects — one person reported sexual dysfunction, another reported shaking hands and numbness around the mouth, and others reported fatigue or headache — but it's unclear whether magnolia was responsible. Magnolia is rated unsafe in pregnancy due to concerns it may affect the uterus, so avoid it if you're pregnant.

There isn't enough safety data on magnolia during breastfeeding, so it's best avoided then too.

Side effects, ingredient by ingredient Magnolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Magnolia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 351 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking SedaLin, double-check any CNS depressants you're on — sedatives, sleep aids, or strong pain relievers — since magnolia may boost their effect (Moderate). Also flag any blood thinners or antiplatelet drugs like warfarin, aspirin, or clopidogrel, which could have increased bleeding risk (Moderate).

Use the medication checker below to run your full list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

SedaLin may interest people exploring magnolia for relaxation or gum health, though the evidence for anxiety and other uses isn't solid yet. If you take any sedating medications or blood thinners, you'll need to check with your doctor or pharmacist before starting — these are genuine interaction concerns.

Pregnant people and those breastfeeding should skip it. It's a conversation starter with your own healthcare provider, not a solo decision.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about SedaLin, straight from the product label.

Brand XYMOGEN
Barcode (UPC) 871149001070
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Apr 23, 2020
DSLD ID 218162
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for SedaLin by XYMOGEN, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
871149001070
IngredientAmount% DV
Magnolia officinalis0 NP--
Seditol730 mg--
Ziziphus spinosa extract0 NP--

Other ingredients: HPMC, Magnesium Stearate, Stearic Acid, Microcrystalline Cellulose, Calcium Silicate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Professional use only Not for resale on third-party websites, including, but not limited to, Amazon and eBay.

Exclusive professional formulas

Scan to learn more! This package is completely recyclable

Suggested/Recommended/Usage/Directions

Directions: Take one to two capsules before bedtime, or as directed by your healthcare practitioner.

To achieve maximum effectiveness, this non-addictive formula should be taken for a minimum of seven nights in a row and may be taken indefinitely.

Precautions

Consult your healthcare practitioner prior to use.

Do not take if pregnant or lactating. Do not take if currently taking any prescription medication or receiving medical treatment without consulting your physician.

Keep out of the reach of children.

Do not use if tamper seal is damaged.

Formula

SedaLin is an all-natural herbal blend of Magnolia officinalis and Ziziphus spinosa formulated to support restful sleep.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Storage: Keep closed in a cool, dry place out of reach of children.

Formulation

Does not contain: Wheat, gluten, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.

Sleep support

GMP Compliant Third-party verified

Vegetarian Caps

Seals/Symbols

ePV (ePedigree Verification)

GMP compliant Third-party verified

Vegetarian caps

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Seditol is a registered trademark of NPI, LLC. U.S. Patent No. US 6,814,987

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

SedaLin by XYMOGEN label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

SedaLin label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in SedaLin by XYMOGEN

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Seditol

730 mg per serving

Other (inactive) ingredients: HPMC, Magnesium Stearate, Stearic Acid, Microcrystalline Cellulose, Calcium Silicate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

SedaLin by XYMOGEN Drug Interactions

Want to check YOUR meds against SedaLin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
351Drugs
351 Moderate

Ingredients driving the most interactions

Magnolia officinalis 351

Individual Drug Interactions

The ingredients in SedaLin interact with 351 drugs. Click any drug to see the details.

1 of the 2 ingredients in SedaLin interact with drugs. Each result below shows which ingredient is responsible. Magnolia officinalis

Each ingredient & the kinds of drugs it affects

For each ingredient in SedaLin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Magnolia officinalis2 drug types · 351 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro research shows that the chemicals magnolol and honokiol, isolated from magnolia bark, inhibit platelet aggregation that is experimentally induced by collagen and arachidonic acid. However, they do not inhibit platelet aggregation that is induced by adenosine diphosphate, platelet-activating factor, or thrombin. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
In vitro and animal research shows that constituents extracted from magnolia bark, especially honokiol and magnolol, have sedative effects. These effects may be due to the inhibition of catecholamine release and modulation of gamma-aminobutyric acid-A (GABA-A) receptors.

Likelihood Possible Evidence D
Magnolia officinalis full monograph & interactions
The maker

Brand information

Manufacturer and brand details for SedaLin, from the product label.

XYMOGEN

See all XYMOGEN products
Name
XYMOGEN Exclusive Professional Formulas
Street Address
6900 Kingspointe Pkwy.
City
Orlando
State
FL
ZipCode
32819
Phone Number
800-647-6100
Web Address
www.xymogen.com
Pharmacist Counseling Corner

SedaLin by XYMOGEN: Common Questions

Does SedaLin by XYMOGEN interact with any medications?
Yes. Based on its ingredients, SedaLin has a known interaction with 351 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
SedaLin contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take SedaLin if I'm pregnant?
No — magnolia is rated unsafe in pregnancy because there's concern it may affect the uterus. If you're pregnant or planning to be, skip this product and talk to your doctor or pharmacist about safer options.
Is it okay to use SedaLin while breastfeeding?
The safety data for magnolia during breastfeeding isn't strong enough to call it okay, so it's best avoided. Talk with your doctor or pharmacist about what's safe for you and your baby.
What is magnolia in this product supposed to do?
Magnolia has traditionally been used for relaxation and sleep support. The evidence is strongest for gingivitis (gum swelling), where it's rated possibly effective. For anxiety and other uses, the evidence isn't established enough to rely on.
Does magnolia have side effects?
When taken by mouth, magnolia is generally well tolerated. In clinical trials of combination products, a few people reported side effects like fatigue, headache, shaking hands, or numbness, but it's not clear whether magnolia caused them. If you're applying it to skin, contact dermatitis can occur.
What is Seditol?
Seditol is a proprietary blend — a mixture of ingredients the manufacturer doesn't fully disclose. We have data on magnolia and the other listed components, but not on Seditol itself as a finished ingredient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

SedaLin label
Go deeper

The Full Monographs Behind SedaLin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Magnolia

Interacts with 351 drugs

Magnolia bark and flower buds have a long history in traditional Chinese and Japanese medicine, often for stress, sleep, and digestion. Modern human research is still limited, so we can't be...

Read the full Magnolia monograph →
Sources

Sources & How We Checked

SedaLin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Magnolia 9 references
  1. Kuribara H, Kishi E, Hattori N, et al. The anxiolytic effect of two oriental herbal drugs in Japan attributed to honokiol from magnolia bark. J Pharm Pharmacol 2000;52:1425-9. PubMed
  2. Tachikawa E, Takahashi M, Kashimoto T. Effects of extract and ingredients isolated from Magnolia obovata thunberg on catecholamine secretion from bovine adrenal chromaffin cells. Biochem Pharmacol 2000;60:433-40. PubMed
  3. Jung KY, Kim DS, Oh SR, et al. Magnone A and B, novel anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia fargesii. J Nat Prod 1998;61:808-11.
  4. Garrison R, Chambliss WG. Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Altern Ther Health Med 2006;12:50-4.
  5. Teng CM, Chen CC, Ko FN, et al. Two antiplatelet agents from Magnolia officinalis. Thromb Res 1988;50:757-65. PubMed
  6. Ghys K, De Palma A, Vandevenne A, Werbrouck J, Goossens A. Magnolia officinalis bark extract, a recently identified contact allergen in 'anti-ageing' cosmetics. Contact Dermatitis. 2015 Aug;73(2):130-2.
  7. Raison-Peyron N, Césaire A, Du-Thanh A, Dereure O. Allergic contact dermatitis caused by Magnolia officinalis bark extract in a facial anti-ageing cream. Contact Dermatitis. 2015 Jun;72(6):416-7.
  8. Nilausen TD, Johansen JD, Thyssen JP. Allergic contact dermatitis of the face caused by Magnolia officinalis bark extract. Contact Dermatitis. 2016;75(6):385-87.
  9. Amat-Samaranch V, López-Sánchez C, Tubau C, Puig L, Serra-Baldrich E. Vulvar allergic contact dermatitis caused by Magnolia officinalis bark extract. Contact Dermatitis 2022;87(1):96-97.

See these in context on the Magnolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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