Selenium 50 mcg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Selenium 50 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Selenium 50 mcg is a dietary supplement by Wonder Laboratories with 1 active ingredient. Its ingredients are commonly taken for thyroid health support, antioxidant support, immune support.Based on those ingredients, 321 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Selenium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Selenium 50 mcg by Wonder Laboratories
Ask about any prescription or over-the-counter medication and we check it for interactions with Selenium 50 mcg by Wonder Laboratories — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Selenium 50 mcg by Wonder Laboratories
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: selenium in the form of selenium amino acid chelate, a bound form designed to support absorption. At 50 micrograms per tablet, it's a modest dose compared to the upper safe limit of 400 mcg daily.
The tablet also includes several inactive ingredients — calcium carbonate, vegetable cellulose, vegetable stearic acid, vegetable magnesium silicate, silica, and vegetable magnesium stearate — which are binders, fillers, and flow agents that hold the tablet together.
Does it work?
Strong evidence
Selenium is likely effective for treating selenium deficiency, the clearest evidence-backed use. There's possibly effective evidence for Kashin-Beck disease (a joint and bone condition linked to selenium shortage), pre-eclampsia (high blood pressure in pregnancy), and autoimmune thyroiditis (an immune-related thyroid condition).
The data suggests it's possibly ineffective for dyslipidemia (abnormal blood fat levels). For other uses beyond these, the evidence we hold doesn't establish effectiveness.
How safe is it?
Well-documented data
Selenium at recommended doses — this product's 50 mcg is well below the safe upper limit of 400 mcg daily — is generally well tolerated. The most common side effects at normal doses are mild: gastric discomfort, headache, and rash.
However, doses above the safe limit can cause hair loss, skin inflammation, fatigue, nail changes, nausea, vomiting, and weight loss. In rare cases, excessive selenium has led to multi-organ failure and death.
Long-term high-dose exposure may also raise the risk of motor nerve damage. The safety data for pregnancy is mixed — rated possibly safe in some contexts and possibly unsafe in others — so talk with your doctor or pharmacist about whether this dose is right for you if you're pregnant or breastfeeding.
Meds to double-check
Moderate interaction found
Before starting this product, double-check your medications with your doctor or pharmacist, especially if you take blood thinners or antiplatelet drugs (Moderate risk of bleeding), immune-suppressing medications (Moderate risk of reduced effectiveness), barbiturates (Moderate risk of prolonged sedation), warfarin (Moderate risk of interference), niacin (Minor risk of reduced cholesterol benefit), or hormonal birth control (Minor — may raise selenium levels).
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
This low-dose selenium supplement makes sense if you have a documented selenium deficiency or are interested in its possibly effective uses (Kashin-Beck disease, pre-eclampsia, autoimmune thyroiditis). It's generally well tolerated at this 50 mcg dose, which stays safely below the toxic threshold.
However, if you take blood thinners, immune-suppressing drugs, barbiturates, warfarin, or niacin, check with your doctor or pharmacist before adding it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 18, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Selenium 50 mcg, straight from the product label.
| Brand | Wonder Laboratories |
|---|---|
| Barcode (UPC) | 099528603107 |
| Net contents | 100 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Dec 18, 2021 |
| DSLD ID | 262404 |
| Product type | Mineral |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Selenium 50 mcg by Wonder Laboratories, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Selenium | 50 mcg | 71% |
| Selenium Amino Acid Chelate | 25 mg | -- |
Other ingredients: Calcium Carbonate, Vegetable Cellulose, Vegetable Stearic Acid, Vegetable Magnesium Silicate, Silica, Vegetable Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Tamper evident: Do not use this product if imprinted foil seal under cap is broken or missing.
Keep out of reach of children.
Formulation
Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)
Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.
Made in USA
Amino acid chelated
"Yeast free"
Antioxidant and immune health Helps neutralize cell damaging free radicals
Gluten free
Storage
Keep tightly closed. Store at room temperature: 59 degrees – 86 degrees F (15 degrees – 30 degrees C).
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Formula 603
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take one tablet daily.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Selenium 50 mcg by Wonder Laboratories label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Selenium 50 mcg by Wonder Laboratories
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container100 Amounts shown are per serving.
Selenium
Interacts with321 drugs
Selenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health. Most people who...
Selenium monograph & interactionsOther (inactive) ingredients: Calcium Carbonate, Vegetable Cellulose, Vegetable Stearic Acid, Vegetable Magnesium Silicate, Silica, Vegetable Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Selenium 50 mcg by Wonder Laboratories Drug Interactions
HelloPharmacist Interaction Report
Wonder Laboratories Selenium 50 mcg interacts with several medication types through its selenium amino acid chelate form.
The most serious concern is with blood thinners (anticoagulants) and antiplatelet drugs — selenium may increase bleeding risk by boosting a compound called prostacyclin that inhibits platelet activity, and it may also interfere with warfarin specifically by affecting how your liver processes it.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to flag immune-suppressing medications, since selenium may stimulate your immune system and potentially reduce their effectiveness. Barbiturates (sedative drugs) are another consideration — selenium may slow how your body breaks them down, prolonging their sedating effects.
Additionally, selenium might reduce the cholesterol-raising benefits of niacin.
Finally, there's a minor interaction with hormonal birth control, which may increase how much selenium your body holds, though we don't yet know if this matters clinically.
Altogether, these interactions span 321 individual medications. Use the medication checker on this page to look up your exact drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Selenium 50 mcg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Selenium 50 mcg interact with 321 drugs. Click any drug to see the details.
1 of the 1 ingredient in Selenium 50 mcg interact with drugs. Each result below shows which ingredient is responsible. Selenium
AnisindioneMiradon
How Anisindione interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Anisindione interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Antithrombin Iii interactionAntithymocyte GlobulinThymoglobulin
How Antithymocyte Globulin interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium Amino Acid Chelate + Antithymocyte Globulin interactionApixabanEliquis
How Apixaban interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Apixaban interactionAprobarbital, Butabarbital, PhenobarbitalTriple Barbital
How Aprobarbital, Butabarbital, Phenobarbital interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium Amino Acid Chelate + Aprobarbital, Butabarbital, Phenobarbital interactionArgatrobanArgatroban
How Argatroban interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs, Barbiturates Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium OxideBufferin
How Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interactionAspirin, CarisoprodolSoma Compound
How Aspirin, Carisoprodol interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Carisoprodol interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Citric Acid, Sodium BicarbonateAlka-Seltzer Pain Reliever and Antacid
How Aspirin, Citric Acid, Sodium Bicarbonate interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Citric Acid, Sodium Bicarbonate interactionAspirin, Codeine PhosphateAspirin w/ Codeine
How Aspirin, Codeine Phosphate interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
How Aspirin, Codeine Phosphate, Methocarbamol interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Codeine Phosphate, Methocarbamol interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs, Barbiturates Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAspirin, DipyridamoleAggrenox, Asasantin Retard
How Aspirin, Dipyridamole interacts with Selenium 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Selenium Amino Acid ChelateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium Amino Acid Chelate + Aspirin, Dipyridamole interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Selenium 50 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Selenium
Anticoagulant/Antiplatelet Drugs
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Clinical research suggests that taking selenium 10 mcg/kg/day can increase bleeding times by increasing prostacyclin production, which inhibits platelet activity. Other clinical research suggests that taking selenium 75 mcg daily, in combination with ascorbic acid 600 mg, alpha-tocopherol 300 mg, and beta-carotene 27 mg, reduces platelet aggregation.
Barbiturates
Theoretically, selenium might prolong the sedating effects of barbiturates.
Laboratory research suggests that selenium can inhibit the hepatic metabolism of barbiturates. Selenium seems to prolong the sedative effect of pentobarbital in animal models.
Immunosuppressants
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
In vitro research and preliminary clinical evidence suggests that selenium may stimulate the immune system.
Warfarin (Coumadin)
Theoretically, selenium might interfere with warfarin activity.
Animal research suggests that selenium can increase warfarin activity. Selenium might interact with warfarin by displacing it from albumin binding sites, reducing its metabolism in the liver, or by decreasing production of vitamin K-dependent clotting factors. Selenium can also prolong bleeding times in humans by increasing prostacyclin production, which inhibits platelet activity.
Contraceptive Drugs
Contraceptive drugs might increase levels of selenium, although the clinical significance of this effect is unclear.
Some research suggests that oral contraceptives increase serum selenium levels in women taking oral contraceptives; however, other research shows no change in selenium levels. It is suggested that an increase could be due to increased carrier proteins, indicating a redistribution of selenium rather than a change in total body selenium.
Niacin
Selenium might reduce the beneficial effects of niacin on high-density lipoprotein (HDL) levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as selenium, or to the combination. It also is not known whether it will occur in other patient populations.
Brand information
Manufacturer and brand details for Selenium 50 mcg, from the product label.
Wonder Laboratories
See all Wonder Laboratories products- Name
- Wonder Laboratories
- Street Address
- 115 S.C.T. Ct.
- City
- White House
- State
- TN
- ZipCode
- 37188
Selenium 50 mcg by Wonder Laboratories: Common Questions
Does Selenium 50 mcg by Wonder Laboratories interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is 50 mcg selenium safe to take daily?
What does selenium actually do?
Can I take this if I'm pregnant?
Does this product have fillers or other ingredients?
Will this help my thyroid?
What happens if I take too much selenium?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Selenium 50 mcg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Selenium 50 mcg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Selenium 50 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 36 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Selenium 36 references
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
- Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-93. DOI
- Trafikowska U, Zachara BA, Wiacek M, et al. Selenium supply and glutathione peroxidase activity in breastfed Polish infants. Acta Paediatr 1996;85:1143-5. PubMed
- Duffield-Lillico AJ, Slate EH, Reid ME, et al. Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial. J Natl Cancer Inst 2003;95:1477-81.. PubMed
- Cheung MC, Zhao XQ, Chait A, et al. Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL. Arterioscler Thromb Vasc Biol 2001;21:1320-6. PubMed
- Schiavon R, Freeman GE, Guidi GC, et al. Selenium enhances prostacyclin production by cultured endothelial cells: possible explanation for increased bleeding times in volunteers taking selenium as a dietary supplement. Thromb Res 1984;34:389-96. PubMed
- Davila JC, Edds GT, Osuna O, Simpson CF. Modification of the effects of aflatoxin B1 and warfarin in young pigs given selenium. Am J Vet Res 1983;44:1877-83. DOI
- Heese HD, Lawrence MA, Dempster WS, Pocock F. Reference concentrations of serum selenium and manganese in healthy nulliparas. S Afr Med J 1988;73:163-5.
- Lloyd B, Lloyd RS, Clayton BE. Effect of smoking, alcohol and other factors on the selenium status of a healthy population. J Epidemiol Commun Health 1983;37:213-7. PubMed
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