Sharp Thought Ingredients & Drug Interactions
by Country Life
What is this page for?
First and foremost: checking Sharp Thought against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Sharp Thought is a dietary supplement by Country Life with 2 active ingredients. Its ingredients are commonly taken for memory and cognitive support, age-related cognitive decline, attention and focus (adhd).Based on those ingredients, 219 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Phosphatidylserine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Sharp Thought by Country Life
Ask about any prescription or over-the-counter medication and we check it for interactions with Sharp Thought by Country Life — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Sharp Thought by Country Life
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Sharp Thought has two active ingredients: docosahexaenoic acid, an omega-3 fatty acid, and phosphatidylserine (supplied as Sharp-PS Gold, a branded form). The rest of the capsule is made up of inactive ingredients like cellulose, hypromellose, and silica, which help hold the formula together.
Does it work?
Moderate evidence
Phosphatidylserine is possibly effective for age-related cognitive decline and Alzheimer's disease, according to the evidence we have. For other uses listed — athletic performance, attention problems, general cognition, and dementia — the evidence isn't strong enough to make a confident claim.
We hold no effectiveness data for docosahexaenoic acid in this product.
How safe is it?
Well-documented data
Phosphatidylserine is generally well tolerated in studies, though long-term safety hasn't been fully established. The most common side effects are flatulence, stomach upset, headache, trouble sleeping, and nausea.
Insomnia is more likely at higher doses (around 600 mg), and digestive upset can show up at 200–300 mg per day. The safety data advises against use during pregnancy and while breastfeeding, because there isn't enough information to know it's safe in those situations.
Talk with your doctor or pharmacist about your individual circumstances if you're pregnant, planning to become pregnant, or nursing.
Meds to double-check
Moderate interaction found
Before taking Sharp Thought, double-check with your pharmacist if you use anticholinergic drugs (like medications for overactive bladder or Parkinson's) or cholinergic drugs (like some dementia treatments) — phosphatidylserine may affect how these work.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product may help with age-related memory decline or early Alzheimer's disease, but the evidence for other cognitive uses is still unclear. If you take anticholinergic or cholinergic medications, check with your pharmacist first — phosphatidylserine could theoretically interfere with how they work.
Avoid it in pregnancy and while breastfeeding unless your doctor says otherwise.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Sharp Thought, straight from the product label.
| Brand | Country Life |
|---|---|
| Barcode (UPC) | 015794049487 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 24, 2025 |
| DSLD ID | 327619 |
| Product type | Fat/fatty Acid |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Sharp Thought by Country Life, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Docosahexaenoic Acid | 8 mg | -- |
| Phosphatidylserine | 100 mg | -- |
| Sharp-PS Gold | 223 mg | -- |
Other ingredients: Microcrystalline Cellulose, Hypromellose, Maltodextrin, Magnesium Stearate, Stearic Acid, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
SharpThought contains a very special conjugated complex of phosphatidylserine (PS) and DHA and Omega-3 fatty acid (Sharp-PS Gold).
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Yes Certified Gluten-free by GFCO.org No yeast, wheat or milk No salt or preservatives No artificial colors, flavors or sweeteners Purity tested for heavy metals including mercury.
Yes Manufacturing supports wind power This product has been manufactured at a GMP Registered facility.
Triple Action Clinically shown to: Support memory Support faster recall Increase mental clarity Based on three (3) capsules daily.
Certified Gluten-free
Our pledge of integrity Authenticity Cleanliness Freshness Consistency Accuracy
General Statements
Yes Recyclable Packaging
Brand IP Statement(s)
Sharp-PS is a registered trademark of Frutarom.
Established 1971 Country Life
Seals/Symbols
Certified B Corporation Certified Gluten Free GFCO.org
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Adults take one (1) capsule one (1) to three (3) times daily with food. As a reminder, discuss the supplements and medications that you take with your health care providers.
Precautions
Contains soy and fish (blue whiting, herring).
Caution: If you are pregnant or nursing, under medical care, taking medication, have a medical condition or planning surgery, consult a doctor before using this product.
Stop using and consult a doctor if any adverse reactions occur. Do not exceed recommended dosage. Do not accept if seal is broken.
Keep out of the reach of children.
Storage
Store in a dry place between 59 degrees - 86 degrees F, avoiding exposure to light.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Sharp Thought by Country Life label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Sharp Thought by Country Life
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sharp-PS Gold
- › Docosahexaenoic Acid
- › Phosphatidylserine
Other (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, Maltodextrin, Magnesium Stearate, Stearic Acid, Silica. These complete the product’s ingredient list but are not active constituents.
Sharp Thought by Country Life Drug Interactions
HelloPharmacist Interaction Report
Sharp Thought by Country Life contains phosphatidylserine, which has documented interactions with two drug types.
The most serious concern is with anticholinergic drugs (used for conditions like overactive bladder and Parkinson's disease) — phosphatidylserine is thought to boost acetylcholine levels, which could theoretically reduce how well these drugs work. This is a Moderate-severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Phosphatidylserine may also have additive effects with cholinergic drugs (medications that increase acetylcholine activity, like some dementia or Alzheimer's treatments). Again, this is Moderate severity — the combination might amplify cholinergic effects more than intended.
We could not check the other active ingredient, docosahexaenoic acid (an omega-3 fatty acid), because interaction data isn't held on file for it. Altogether, these interactions span 218 individual medications.
Please use the search tool below to check your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Sharp Thought?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Sharp Thought interact with 219 drugs. Click any drug to see the details.
1 of the 2 ingredients in Sharp Thought interact with drugs. Each result below shows which ingredient is responsible. Phosphatidylserine
AmifampridineRuzurgi
How Amifampridine interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineCholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Read the full Phosphatidylserine + Amifampridine interactionAmifampridine PhosphateFirdapse
How Amifampridine Phosphate interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineCholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Read the full Phosphatidylserine + Amifampridine Phosphate interactionAminoglutethimideCytadren
How Aminoglutethimide interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Aminoglutethimide interactionAmitriptylineElavil
How Amitriptyline interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Amitriptyline, Perphenazine interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAtropineSal-Tropine
How Atropine interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine interactionAtropine Methyl Nitrate, Digestive EnzymesFestalan
How Atropine Methyl Nitrate, Digestive Enzymes interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine Methyl Nitrate, Digestive Enzymes interactionAtropine SulfateAtropine Sulfate, Isopto Atropine
How Atropine Sulfate interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine Sulfate interactionAtropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, PhenylAtrosept
How Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl interactionAtropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl SalicylateUrinary Antiseptic 2, Urised
How Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl Salicylate interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl Salicylate interactionAtropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, ScopolamineAtrohist Plus, Pro Tuss, Ru-tuss, Stahist
How Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interactionAtropine, DifenoxinMotofen
How Atropine, Difenoxin interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Difenoxin interactionAtropine, DiphenoxylateLofene, Lomotil
How Atropine, Diphenoxylate interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Diphenoxylate interactionAtropine, Hyoscyamine, PhenobarbitalHypnaldyne
How Atropine, Hyoscyamine, Phenobarbital interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Hyoscyamine, Phenobarbital interactionAtropine, Hyoscyamine, Phenobarbital, ScopolamineBarbidonna No. 2, Belladonna Phenobarbital
How Atropine, Hyoscyamine, Phenobarbital, Scopolamine interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Hyoscyamine, Phenobarbital, Scopolamine interactionAtropine, Hyoscyamine, ScopolamineColytrol
How Atropine, Hyoscyamine, Scopolamine interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Hyoscyamine, Scopolamine interactionAtropine, Hyoscyamine, Scopolamine, PhenobarbitalBarbeloid, Donnatal #2, Donphen
How Atropine, Hyoscyamine, Scopolamine, Phenobarbital interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Hyoscyamine, Scopolamine, Phenobarbital interactionAtropine, PhenobarbitalAnthrocol
How Atropine, Phenobarbital interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Phenobarbital interactionAtropine, MeperidineAtropine, Meperidine
How Atropine, Meperidine interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Meperidine interactionAtropine, Morphine SulfateAtropine, Morphine Sulfate
How Atropine, Morphine Sulfate interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Atropine, Morphine Sulfate interactionBarbital, Hyoscyamine, Scopolamine, Passiflora, ValeriBarbatose #2
How Barbital, Hyoscyamine, Scopolamine, Passiflora, Valeri interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Barbital, Hyoscyamine, Scopolamine, Passiflora, Valeri interactionBelladonna Alkaloids (prescription Drug)Bellafoline
How Belladonna Alkaloids (prescription Drug) interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Belladonna Alkaloids (prescription Drug) interactionBelladonna Alkaloids, Chlorpheniramine, Phenylephrine, PhenylpropanolamineRespa ARM
How Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interactionBelladonna Alkaloids, Ergotamine Tartrate, PhenobarbitalBel Tabs, Bellamine-S, Bellaphen-S, Duragal S, Phenarbal S, Spastrin
How Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interactionBelladonna Alkaloids, PhenobarbitalBarbidonna, Donnatal
How Belladonna Alkaloids, Phenobarbital interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Belladonna Alkaloids, Phenobarbital interactionBelladonna Extract, Butabarbital SodiumButibel
How Belladonna Extract, Butabarbital Sodium interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Belladonna Extract, Butabarbital Sodium interactionBelladonna Extract, PhenobarbitalBelap
How Belladonna Extract, Phenobarbital interacts with Sharp Thought — through 1 ingredient. Tap an ingredient for the detail:
PhosphatidylserineAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Phosphatidylserine + Belladonna Extract, Phenobarbital interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Sharp Thought with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Phosphatidylserine
Anticholinergic Drugs
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically interfere with the activity of anticholinergic agents.
Cholinergic Drugs
Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically lead to additive cholinergic effects when used with cholinergic drugs.
Brand information
Manufacturer and brand details for Sharp Thought, from the product label.
Country Life
See all Country Life products- Name
- Country Life, LLC
- Street Address
- 180 Vanderbilt Motor Parkway
- City
- Hauppauge
- State
- NY
- ZipCode
- 11788
- Web Address
- CountryLifeVitamins.com
Sharp Thought by Country Life: Common Questions
Does Sharp Thought by Country Life interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is phosphatidylserine, and what does it do?
Does this product actually work for memory problems?
What side effects might I experience?
Can I take this if I'm pregnant or breastfeeding?
What's docosahexaenoic acid, and why is it in here?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Sharp Thought is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Sharp Thought’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Sharp Thought's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 9 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Phosphatidylserine 9 references
- Crook T, Petrie W, Wells C, Massari DC. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull 1992;28:61-6.
- Pepping J. Phosphatidylserine. Am J Health-Syst Pharm 1999;56:2038,2043-4.
- Kidd PM. Phosphatidylserine; Membrane nutrient for memory. A clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.
- Kim HY, Akbar M, Lau A, et al. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem 2000;275:35215-23.. PubMed
- Zanotti A, Valzelli L, Toffano G. Chronic phosphatidylserine treatment improves spatial memory and passive avoidance in aged rats. Psychopharmacology (Berl) 1989;99:316-21.. PubMed
- Schreiber S, Kampf-Sherf O, Gorfine M, et al. An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline. Isr J Psychiatry Relat Sci 2000;37:302-7.
- Pepping, J. Phosphatidylserine. Am J Health Syst.Pharm. 10-15-1999;56(20):2038, 2043-2038, 2044.
- Monteverde, A., Gnemmi, P., Rossi, F., Monteverde, A., and Finali, G. C. Selegiline in the treatment of mild to moderate Alzheimer-type dementia. Clin.Ther 1990;12(4):315-322.
- Vakhapova V, Cohen T, Richter Y, Herzog Y, Kam Y, Korczyn AD. Phosphatidylserine containing omega-3 Fatty acids may improve memory abilities in nondemented elderly individuals with memory complaints: results from an open-label extension study. Dement Geri PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC