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Dietary supplement

SinuCare Extra Strength Ingredients & Drug Interactions

by Terry Naturally

Softgel Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

SinuCare Extra Strength is a dietary supplement by Terry Naturally with 3 active ingredients. Its ingredients are commonly taken for cough and chest congestion, colds and flu symptoms, stuffy nose.Based on those ingredients, 878 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Eucalyptus (Eucalyptus radiata) leaf oil, Lemon (Citrus limon) zest Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of SinuCare Extra Strength by Terry Naturally

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Double Strength Proprietary Formula” is a proprietary blend — the label gives one combined amount (325 mg) without saying how much of each component you get.

SinuCare Extra Strength contains 3 active ingredients: eucalyptus leaf oil, lemon zest oil, and myrtle leaf oil—all essential oils intended to support respiratory and sinus function. The formula is packaged in softgel capsules with an enteric coating, which allows the oils to release in the intestines rather than the stomach.

The capsules also contain olive oil, gelatin, glycerol, water, and the coating itself as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: supports sinus and bronchial airway passages.
  • We looked for evidence on: Rhinosinusitis, Bronchitis, Cough, Respiratory tract infections, Allergic rhinitis (hay fever), Asthma — and 4 related terms.
  • The closest evidence on file: Lemon is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Lemon is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections.
  • Also on file: Myrtle is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections.

The effectiveness of each ingredient in this product has not been reliably established. Eucalyptus has insufficient evidence for acne, bronchitis, asthma, burns, and cancer.

Lemon zest has insufficient evidence for hay fever, anxiety, respiratory tract infections, high blood pressure, and kidney stones. Myrtle leaf also has insufficient evidence for acne, bacterial vaginosis, respiratory infections, diarrhea, acid reflux, and gum disease.

While these oils are used traditionally, the clinical data to confirm they work for sinus or respiratory support is not yet available.

The evidence, ingredient by ingredient Eucalyptus Lemon Myrtle

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Eucalyptus oil is generally well tolerated in small, diluted amounts, but the undiluted oil can be poisonous if swallowed—toxicity can occur at doses as low as 1 mL and cause serious effects including seizures, coma, and death. Common side effects from diluted oral use are diarrhea, nausea, and vomiting.

Lemon is generally safe in food amounts, though regular consumption of fresh lemon juice can cause heartburn and stomach discomfort in some people; one trial found 37% of users experienced gastrointestinal upset versus 8% on placebo. Myrtle leaf has limited safety data and is rated likely unsafe in pregnancy and unknown during breastfeeding, so avoid it if you're pregnant or nursing.

Topically, myrtle may cause dry skin, and in infants and children, inhaled myrtle oil can trigger bronchial spasm or asthma-like attacks.

Side effects, ingredient by ingredient Eucalyptus Lemon Myrtle

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Lemon, Eucalyptus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 879 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against the search tool below before you start, especially if you take diabetes drugs (risk of low blood sugar), medications processed by liver enzymes CYP1A2, CYP2C19, CYP2C9, or CYP3A4, amphetamines, pentobarbital, or itraconazole. The eucalyptus and lemon in this product may affect how these drugs work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is designed for sinus and respiratory support, but clinical evidence for its ingredients is not established. The main concern is eucalyptus, which may interact with liver enzymes and diabetes medications—if you take any prescription drugs, check them against the tool on this page.

Pregnant or breastfeeding women should avoid it. Talk with your doctor or pharmacist before starting, especially if you have diabetes, take antifungals, or use stimulants.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about SinuCare Extra Strength, straight from the product label.

Brand Terry Naturally
Barcode (UPC) 367703325039
Net contents 30 Enteric-Coated Softgel(s)
Market status On market
Date entered into DSLD May 24, 2018
DSLD ID 177225
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for SinuCare Extra Strength by Terry Naturally, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Enteric-Coated Softgel(s)
Maximum serving Sizes:
1 Enteric-Coated Softgel(s)
Servings per container
30
UPC/BARCODE
367703325039
IngredientAmount% DV
Eucalyptus (Eucalyptus radiata) leaf oil0 NP--
Lemon (Citrus limon) zest Oil0 NP--
Myrtle (Myrtus communis) leaf oil0 NP--
Double Strength Proprietary Formula325 mg--

Other ingredients: extra virgin Olive Oil, Gelatin, Glycerol, Water, Enteric Coating

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

No sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, or artificial preservatives.

Non-GMO

Suggested/Recommended/Usage/Directions

Recommendations: 1 enteric-coated softgel, up to 3 times daily or as needed. Do not chew.

Precautions

Do not chew.

If pregnant or nursing, consult a health care practitioner before using.

Storage

Store in a cool, dry place.

General Statements

- Powerful action, safe results you’ll notice - Does not cause drowsiness, jitteriness or nasal dryness - Enteric-coated softgel—no burping or after-taste - Supports both the sinus and bronchial airway passages

Enteric-coated to eliminate burping or after-taste. SinuCare Extra-Strength supports the cilia of the sinuses, which brush mucus out of the sinus and nasal cavities. Healthy cilia function is required for clear and comfortable sinuses.

No after-taste Non-drowsy

Sinus, bronchial, and lung support Soothes mucous membranes Effective results For your good health Terry

Money-back guarantee

Product of Belgium

Brand IP Statement(s)

Why SinuCare Extra Strength? More powerful!

Terry Naturally EuroPharma

Formula

Provides more of the powerful eucalyptus and myrtle found in SinuCare, with the additional synergistic strength of lemon.

Powerful ingredients SinuCare Extra Strength provides Eucalyptus, Myrtle and Lemon oil to support sinus, bronchial, lung, and entire upper respiratory function. - Refreshing Eucalyptus (Eucalyptus radiata) has long been studied and shown to support healthy, clear sinus passages. - Strong Myrtle (Myrtus communis) supports a healthy respiratory environment, and provides the key compound, 1,8 cineole for effective support! - Powerful Lemon (Citrus limon) for additional sinus and immune support.

With Eucalyptus

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

JC 34 91 + 3(5,6)EP BX32503.03

See for yourself

SinuCare Extra Strength by Terry Naturally label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in SinuCare Extra Strength by Terry Naturally

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Enteric-Coated Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Double Strength Proprietary Formula

325 mg per serving

Other (inactive) ingredients: Extra virgin Olive Oil, Gelatin, Glycerol, Water, Enteric Coating. These complete the product’s ingredient list but are not active constituents.

Interaction report

SinuCare Extra Strength by Terry Naturally Drug Interactions

Want to check YOUR meds against SinuCare Extra Strength?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
878Drugs
878 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in SinuCare Extra Strength with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Eucalyptus (Eucalyptus radiata) leaf oil7 drug types · 878 drugs

Amphetamines

Theoretically, inhaling eucalyptol may reduce the effectiveness of amphetamines.
Animal research suggests that inhaling eucalyptol may reduce the levels of amphetamines in the blood.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, eucalyptus leaf might increase the risk of hypoglycemia.
Animal research suggests that eucalyptus leaf might have hypoglycemic activity, and might have additive effects when used with antidiabetes drugs.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP1A2, although this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, eucalyptus might increase the levels of CYP2C19 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP2C19, although this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, eucalyptus might increase the levels of CYP2C9 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP2C9, although this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, eucalyptus might increase the levels of CYP3A4 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP3A4, although this has not been reported in humans.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, inhaling eucalyptol might reduce the effectiveness of pentobarbital.
Animal research suggests that inhaling eucalyptol reduces the level of pentobarbital that reaches the brain.

Likelihood Possible Evidence D

Lemon (Citrus limon) zest Oil1 drug type · 1 drug

Itraconazole (Sporanox)

Theoretically, taking itraconazole capsules or tablets with a beverage containing lemon might increase the levels and clinical effects of itraconazole.
In one case report, dissolving itraconazole tablets in a small amount of specific beverages containing lemon prior to administration increased the level of itraconazole in a lung transplant patient. In this case, the increased bioavailability was desirable and was likely due to improved tablet dissolution in the acidic beverage.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for SinuCare Extra Strength, from the product label.

Terry Naturally

See all Terry Naturally products
Name
EuroPharma, Inc.
City
Green Bay
State
WI
ZipCode
54311
Phone Number
(866) 807-2731
Web Address
EuroPharmaUSA.com
Pharmacist Counseling Corner

SinuCare Extra Strength by Terry Naturally: Common Questions

Does SinuCare Extra Strength by Terry Naturally interact with any medications?
Yes. Based on its ingredients, SinuCare Extra Strength has a known interaction with 878 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
SinuCare Extra Strength contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is eucalyptus oil safe to swallow in this softgel?
Undiluted eucalyptus oil is toxic if swallowed, with serious effects possible at doses as low as 1 mL. This product delivers oil in a softgel with an enteric coating; check with your doctor before taking it to make sure the dose and form are safe for you.
Can I take this while pregnant or breastfeeding?
Eucalyptus and lemon are rated likely safe in pregnancy, but myrtle is rated likely unsafe. Myrtle is also not recommended while breastfeeding because safety data is unknown. Talk with your doctor or pharmacist before taking this product if you're pregnant or nursing.
Will this help my sinus or respiratory problems?
There isn't enough reliable clinical evidence to confirm that eucalyptus, lemon, or myrtle oils work for sinus or respiratory conditions. The data we hold shows insufficient evidence for each ingredient for these uses.
What are the most common side effects?
From eucalyptus, the most common side effects of diluted oral use are diarrhea, nausea, and vomiting. Lemon juice commonly causes heartburn and stomach discomfort. Myrtle has limited safety data, but topical use has been reported to cause dry skin.
Does lemon in this product interact with my antifungal medication?
Yes—if you take itraconazole (Sporanox), the lemon zest oil in this softgel may increase itraconazole levels in your blood. Check with your doctor or pharmacist before combining them.
Can this product affect my diabetes medication?
Eucalyptus may theoretically increase the risk of low blood sugar (hypoglycemia) when combined with diabetes drugs. If you take any blood-sugar–lowering medications, talk with your doctor or pharmacist before starting this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if SinuCare Extra Strength is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

SinuCare Extra Strength label
Sources

Sources & How We Checked

SinuCare Extra Strength's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 28 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eucalyptus 23 references
  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  2. Unger M, Frank A. Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction. Rapid Commun Mass Spectrom 2004;1 PubMed
  3. De Vincenzi M, Silano M, De Vincenzi A, et al. Constituents of aromatic plants: eucalyptol. Fitoterapia 2002;73:269-75. PubMed
  4. Gray AM, Flatt PR. Antihyperglycemic actions of Eucalyptus globulus (Eucalyptus) are associated with pancreatic and extra-pancreatic effects in mice. J Nutr 1998;128:2319-23. PubMed
  5. Whitman BW, Ghazizadeh H. Eucalyptus oil: therapeutic and toxic aspects of pharmacology in humans and animals. J Paediatr Child Health 1994;30:190-1. PubMed
  6. Barker SC and Altman PM. An ex vivo, assessor blind, randomised, parallel group, comparative efficacy trial of the ovicidal activity of three pediculicides after a single application--melaleuca oil and lavender oil, eucalyptus oil and lemon tea tree oil,
  7. Vilaplana, J. and Romaguera, C. Allergic contact dermatitis due to eucalyptol in an anti-inflammatory cream. Contact Dermatitis 2000;43(2):118.
  8. Juergens, U. R. [Reducing the need for cortisone. Does eucalyptus oil work in asthma? (interview by Brigitte Moreano]. MMW.Fortschr Med 3-29-2001;143(13):14.
  9. Tascini, C., Ferranti, S., Gemignani, G., Messina, F., and Menichetti, F. Clinical microbiological case: fever and headache in a heavy consumer of eucalyptus extract. Clin Microbiol.Infect. 2002;8(7):437, 445-437, 446. PubMed
  10. Galdi, E., Perfetti, L., Calcagno, G., Marcotulli, M. C., and Moscato, G. Exacerbation of asthma related to Eucalyptus pollens and to herb infusion containing Eucalyptus. Monaldi Arch.Chest Dis. 2003;59(3):220-221.
  11. Spoerke, D. G., Vandenberg, S. A., Smolinske, S. C., Kulig, K., and Rumack, B. H. Eucalyptus oil: 14 cases of exposure. Vet Hum.Toxicol 1989;31(2):166-168.
  12. Jori, A., Bianchetti, A., Prestini, P. E., and Gerattini, S. Effect of eucalyptol (1,8-cineole) on the metabolism of other drugs in rats and in man. Eur.J Pharmacol 1970;9(3):362-366. PubMed
  13. Tibballs, J. Clinical effects and management of eucalyptus oil ingestion in infants and young children. Med J Aust 8-21-1995;163(4):177-180. PubMed
  14. Webb, N. J. and Pitt, W. R. Eucalyptus oil poisoning in childhood: 41 cases in south-east Queensland. J Paediatr.Child Health 1993;29(5):368-371. PubMed
  15. Gyldenløve M, Menné T, Thyssen JP. Eucalyptus contact allergy. Contact Dermatitis. 2014;71(5):303-304. PubMed
  16. Higgins C, Palmer A, Nixon R. Eucalyptus oil: contact allergy and safety. Contact Dermatitis. 2015;72(5):344-346. PubMed
  17. de Groot AC, Schmidt E. Eucalyptus oil and tea tree oil. Contact Dermatitis. 2015;73(6):381-386. PubMed
  18. Greive KA, Barnes TM. The efficacy of Australian essential oils for the treatment of head lice infestation in children: A randomised controlled trial. Australas J Dermatol. 2018;59(2):e99-e105. PubMed
  19. Paulsen E, Thormann H, Vestergaard L. Eucalyptus species as a cause of airborne allergic contact dermatitis. Contact Dermatitis. 2018;78(4):301-303.
  20. Mathew T, John SK, Kamath V, et al. Essential oil related seizures (EORS): A multi-center prospective study on essential oils and seizures in adults. Epilepsy Res. 2021;173:106626. PubMed
  21. Dudipala SC, Mandapuram P, Ch LK. Eucalyptus Oil-Induced Seizures in Children: Case Reports and Review of the Literature. J Neurosci Rural Pract 2021;12(1):112-115. PubMed
  22. Panda PK, Sharawat IK, Panda P, Dawman L, Kasinathan A. Clinico-laboratory characteristics and outcome of patients with eucalyptus oil-induced/provoked seizures: A case series and systematic review of the published patients. Trop Doct 2021;51(4):518-522. PubMed
  23. Sai Chandar D, Prashanthi M, Laxman Kumar C, Amith Kumar C. Eucalyptus Oil-Induced Seizures in Children: A Single-Center Prospective Study. Cureus 2021;13(3):e14109. PubMed

See these in context on the Eucalyptus monograph →

Lemon 2 references
  1. Ruggenenti P, Caruso MR, Cortinovis M, et al. Fresh lemon juice supplementation for the prevention of recurrent stones in calcium oxalate nephrolithiasis: A pragmatic, prospective, randomised, open, blinded endpoint (PROBE) trial. EClinicalMedicine 2021;4 PubMed
  2. Umemura K, Katada Y, Nakagawa S, et al. Improved absorption of itraconazole tablet by co-administration with lemon beverages in a lung transplant recipient: A case report. J Infect Chemother 2022;28(8):1203-1207. PubMed

See these in context on the Lemon monograph →

Myrtle 3 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Salmanian M, Shirbeigi L, Hashem-Dabaghian F, et al. The Effects of Myrtle (Myrtus communis) and Clindamycin Topical Solution in the Treatment of Mild to Moderate Acne Vulgaris: A Comparative Split-Face Study. J Pharmacopuncture 2020;23(4):220-229.
  3. Paknejad MS, Eftekhari K, Rahimi R, Vigeh M, Naghizadeh A, Karimi M. Myrtle (Myrtus communis L.) fruit syrup for gastroesophageal reflux disease in children: A double-blind randomized clinical trial. Phytother Res 2021;35(11):6369-6376.

See these in context on the Myrtle monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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