SinuCare Extra Strength Ingredients & Drug Interactions
What is this page for?
First and foremost: checking SinuCare Extra Strength against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
SinuCare Extra Strength is a dietary supplement by Terry Naturally with 3 active ingredients. Its ingredients are commonly taken for cough and chest congestion, colds and flu symptoms, stuffy nose.Based on those ingredients, 878 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Eucalyptus (Eucalyptus radiata) leaf oil, Lemon (Citrus limon) zest Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against SinuCare Extra Strength by Terry Naturally
Ask about any prescription or over-the-counter medication and we check it for interactions with SinuCare Extra Strength by Terry Naturally — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of SinuCare Extra Strength by Terry Naturally
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
SinuCare Extra Strength contains 3 active ingredients: eucalyptus leaf oil, lemon zest oil, and myrtle leaf oil—all essential oils intended to support respiratory and sinus function. The formula is packaged in softgel capsules with an enteric coating, which allows the oils to release in the intestines rather than the stomach.
The capsules also contain olive oil, gelatin, glycerol, water, and the coating itself as inactive ingredients.
Does it work?
Not established
The effectiveness of each ingredient in this product has not been reliably established. Eucalyptus has insufficient evidence for acne, bronchitis, asthma, burns, and cancer.
Lemon zest has insufficient evidence for hay fever, anxiety, respiratory tract infections, high blood pressure, and kidney stones. Myrtle leaf also has insufficient evidence for acne, bacterial vaginosis, respiratory infections, diarrhea, acid reflux, and gum disease.
While these oils are used traditionally, the clinical data to confirm they work for sinus or respiratory support is not yet available.
How safe is it?
Well-documented data
Eucalyptus oil is generally well tolerated in small, diluted amounts, but the undiluted oil can be poisonous if swallowed—toxicity can occur at doses as low as 1 mL and cause serious effects including seizures, coma, and death. Common side effects from diluted oral use are diarrhea, nausea, and vomiting.
Lemon is generally safe in food amounts, though regular consumption of fresh lemon juice can cause heartburn and stomach discomfort in some people; one trial found 37% of users experienced gastrointestinal upset versus 8% on placebo. Myrtle leaf has limited safety data and is rated likely unsafe in pregnancy and unknown during breastfeeding, so avoid it if you're pregnant or nursing.
Topically, myrtle may cause dry skin, and in infants and children, inhaled myrtle oil can trigger bronchial spasm or asthma-like attacks.
Meds to double-check
Moderate interaction found
Check your medications against the search tool below before you start, especially if you take diabetes drugs (risk of low blood sugar), medications processed by liver enzymes CYP1A2, CYP2C19, CYP2C9, or CYP3A4, amphetamines, pentobarbital, or itraconazole. The eucalyptus and lemon in this product may affect how these drugs work.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This product is designed for sinus and respiratory support, but clinical evidence for its ingredients is not established. The main concern is eucalyptus, which may interact with liver enzymes and diabetes medications—if you take any prescription drugs, check them against the tool on this page.
Pregnant or breastfeeding women should avoid it. Talk with your doctor or pharmacist before starting, especially if you have diabetes, take antifungals, or use stimulants.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2018.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about SinuCare Extra Strength, straight from the product label.
| Brand | Terry Naturally |
|---|---|
| Barcode (UPC) | 367703325039 |
| Net contents | 30 Enteric-Coated Softgel(s) |
| Market status | On market |
| Date entered into DSLD | May 24, 2018 |
| DSLD ID | 177225 |
| Product type | Botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for SinuCare Extra Strength by Terry Naturally, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Eucalyptus (Eucalyptus radiata) leaf oil | 0 NP | -- |
| Lemon (Citrus limon) zest Oil | 0 NP | -- |
| Myrtle (Myrtus communis) leaf oil | 0 NP | -- |
| Double Strength Proprietary Formula | 325 mg | -- |
Other ingredients: extra virgin Olive Oil, Gelatin, Glycerol, Water, Enteric Coating
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
No sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, or artificial preservatives.
Non-GMO
Suggested/Recommended/Usage/Directions
Recommendations: 1 enteric-coated softgel, up to 3 times daily or as needed. Do not chew.
Precautions
Do not chew.
If pregnant or nursing, consult a health care practitioner before using.
Storage
Store in a cool, dry place.
General Statements
- Powerful action, safe results you’ll notice - Does not cause drowsiness, jitteriness or nasal dryness - Enteric-coated softgel—no burping or after-taste - Supports both the sinus and bronchial airway passages
Enteric-coated to eliminate burping or after-taste. SinuCare Extra-Strength supports the cilia of the sinuses, which brush mucus out of the sinus and nasal cavities. Healthy cilia function is required for clear and comfortable sinuses.
No after-taste Non-drowsy
Sinus, bronchial, and lung support Soothes mucous membranes Effective results For your good health Terry
Money-back guarantee
Product of Belgium
Brand IP Statement(s)
Why SinuCare Extra Strength? More powerful!
Terry Naturally EuroPharma
Formula
Provides more of the powerful eucalyptus and myrtle found in SinuCare, with the additional synergistic strength of lemon.
Powerful ingredients SinuCare Extra Strength provides Eucalyptus, Myrtle and Lemon oil to support sinus, bronchial, lung, and entire upper respiratory function. - Refreshing Eucalyptus (Eucalyptus radiata) has long been studied and shown to support healthy, clear sinus passages. - Strong Myrtle (Myrtus communis) supports a healthy respiratory environment, and provides the key compound, 1,8 cineole for effective support! - Powerful Lemon (Citrus limon) for additional sinus and immune support.
With Eucalyptus
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General
JC 34 91 + 3(5,6)EP BX32503.03
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
SinuCare Extra Strength by Terry Naturally label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in SinuCare Extra Strength by Terry Naturally
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Enteric-Coated Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Double Strength Proprietary Formula
Other (inactive) ingredients: Extra virgin Olive Oil, Gelatin, Glycerol, Water, Enteric Coating. These complete the product’s ingredient list but are not active constituents.
SinuCare Extra Strength by Terry Naturally Drug Interactions
HelloPharmacist Interaction Report
SinuCare Extra Strength by Terry Naturally contains eucalyptus and lemon zest oils, both of which have documented interactions with medications.
Eucalyptus carries the most serious concern: it may theoretically inhibit several liver enzymes (CYP1A2, CYP2C19, CYP2C9, and CYP3A4), which could raise the blood levels of drugs processed by those pathways. Additionally, eucalyptus may increase the risk of low blood sugar (hypoglycemia) if you take diabetes medications, and animal research suggests it might reduce the effectiveness of amphetamines or pentobarbital.
Read the full breakdown — every affected drug type, severity by severity
Lemon zest oil has a minor interaction: taking itraconazole (an antifungal) with lemon-containing beverages may increase itraconazole levels in your blood. Myrtle leaf oil, the third ingredient, has no interactions documented in our data.
Although these interactions are based on lab studies and animal research rather than confirmed human cases, the potential effects are real enough to warrant checking before you start. Altogether, these interactions span 879 individual medications.
Use the medication checker below to look up your exact prescriptions, and talk with your doctor or pharmacist before taking this product if you use any blood-sugar–lowering drugs, amphetamines, pentobarbital, or itraconazole.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against SinuCare Extra Strength?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in SinuCare Extra Strength interact with 878 drugs. Click any drug to see the details.
2 of the 3 ingredients in SinuCare Extra Strength interact with drugs. Each result below shows which ingredient is responsible. Eucalyptus (Eucalyptus radiata) leaf oil Lemon (Citrus limon) zest Oil
Acetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Acetaminophen, Pamabrom, Pyrilamine interactionAcetaminophen, PentazocineTalacen
How Acetaminophen, Pentazocine interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Acetaminophen, Pentazocine interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetaminophen, PhenylpropanolamineTetra Caps
How Acetaminophen, Phenylpropanolamine interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Acetaminophen, Phenylpropanolamine interactionAcetaminophen, Phenylpropanolamine, PhenyltoloxamineSinubid
How Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, PhenyltoloxaminePercogesic, Relagesic
How Acetaminophen, Phenyltoloxamine interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Acetaminophen, Phenyltoloxamine interactionAcetaminophen, Phenyltoloxamine, SalicylamideLobac
How Acetaminophen, Phenyltoloxamine, Salicylamide interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Acetaminophen, Phenyltoloxamine, Salicylamide interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Acetaminophen, Propoxyphene interactionAcetaminophen, PseudoephedrineChildren's Tylenol Sinus, Dristan N.D., Non-Aspirin Sinus, Ornex, Ornex-Max, Sinutab +5 more
How Acetaminophen, Pseudoephedrine interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Acetaminophen, Pseudoephedrine interactionAcetaminophen, Pseudoephedrine, TriprolidineActifed Plus ES
How Acetaminophen, Pseudoephedrine, Triprolidine interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Acetaminophen, Pseudoephedrine, Triprolidine interactionAcetohexamideDymelor
How Acetohexamide interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eucalyptus leaf might increase the risk of hypoglycemia.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Acetohexamide interactionAdagrasibKrazati
How Adagrasib interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP3A4 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Adagrasib interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP2C19 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAgomelatineValdoxan
How Agomelatine interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates +1 Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP2C19 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Agomelatine interactionAlbiglutideTanzeum
How Albiglutide interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eucalyptus leaf might increase the risk of hypoglycemia.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Albiglutide interactionAlfentanilAlfenta
How Alfentanil interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP3A4 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Alfentanil interactionAlfuzosinUroxatral
How Alfuzosin interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP3A4 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Alfuzosin interactionAliskirenTekturna
How Aliskiren interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP3A4 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Aliskiren interactionAlmotriptanAlmogran, Axert
How Almotriptan interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP3A4 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Almotriptan interactionAlogliptinNesina
How Alogliptin interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilAntidiabetes Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus leaf might increase the risk of hypoglycemia.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eucalyptus leaf might increase the risk of hypoglycemia.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilAntidiabetes Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus leaf might increase the risk of hypoglycemia.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Alogliptin, Pioglitazone interactionAlpelisibPiqray
How Alpelisib interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP3A4 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Alpelisib interactionAlprazolamNiravam, Xanax
How Alprazolam interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP3A4 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Alprazolam interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP3A4 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Ambrisentan interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP3A4 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Amiodarone interactionAmitriptylineElavil
How Amitriptyline interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP2C9 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates +2 Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP2C9 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with SinuCare Extra Strength — through 1 ingredient. Tap an ingredient for the detail:
Eucalyptus (eucalyptus Radiata) Leaf OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eucalyptus might increase the levels of CYP3A4 substrates.
Read the full Eucalyptus (eucalyptus Radiata) Leaf Oil + Amlodipine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in SinuCare Extra Strength with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Eucalyptus (Eucalyptus radiata) leaf oil
Amphetamines
Theoretically, inhaling eucalyptol may reduce the effectiveness of amphetamines.
Animal research suggests that inhaling eucalyptol may reduce the levels of amphetamines in the blood.
Antidiabetes Drugs
Theoretically, eucalyptus leaf might increase the risk of hypoglycemia.
Animal research suggests that eucalyptus leaf might have hypoglycemic activity, and might have additive effects when used with antidiabetes drugs.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP1A2, although this has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, eucalyptus might increase the levels of CYP2C19 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP2C19, although this has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, eucalyptus might increase the levels of CYP2C9 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP2C9, although this has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, eucalyptus might increase the levels of CYP3A4 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP3A4, although this has not been reported in humans.
Pentobarbital (Nembutal)
Theoretically, inhaling eucalyptol might reduce the effectiveness of pentobarbital.
Animal research suggests that inhaling eucalyptol reduces the level of pentobarbital that reaches the brain.
Lemon (Citrus limon) zest Oil
Itraconazole (Sporanox)
Theoretically, taking itraconazole capsules or tablets with a beverage containing lemon might increase the levels and clinical effects of itraconazole.
In one case report, dissolving itraconazole tablets in a small amount of specific beverages containing lemon prior to administration increased the level of itraconazole in a lung transplant patient. In this case, the increased bioavailability was desirable and was likely due to improved tablet dissolution in the acidic beverage.
Brand information
Manufacturer and brand details for SinuCare Extra Strength, from the product label.
Terry Naturally
See all Terry Naturally products- Name
- EuroPharma, Inc.
- City
- Green Bay
- State
- WI
- ZipCode
- 54311
- Phone Number
- (866) 807-2731
- Web Address
- EuroPharmaUSA.com
SinuCare Extra Strength by Terry Naturally: Common Questions
Does SinuCare Extra Strength by Terry Naturally interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is eucalyptus oil safe to swallow in this softgel?
Can I take this while pregnant or breastfeeding?
Will this help my sinus or respiratory problems?
What are the most common side effects?
Does lemon in this product interact with my antifungal medication?
Can this product affect my diabetes medication?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if SinuCare Extra Strength is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind SinuCare Extra Strength’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Eucalyptus
Interacts with 878 drugsEucalyptus is best known for its strong-smelling oil used in vapor rubs, inhalants, and lozenges to ease coughs and congestion. It may provide mild, short-term relief of cold symptoms, but t...
Read the full Eucalyptus monograph → Herb & supplement monographLemon
Interacts with 1 drugLemon is a common citrus fruit that is a good source of vitamin C and citric acid, and it is widely used in food, drinks, and home remedies. While it can support hydration and a healthy diet...
Read the full Lemon monograph → Herb & supplement monographMyrtle
Myrtle (Myrtus communis) is a Mediterranean shrub used traditionally for respiratory, digestive, and skin complaints. Modern research is mostly limited to laboratory and small studies, so it...
Read the full Myrtle monograph →Sources & How We Checked
SinuCare Extra Strength's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 28 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Eucalyptus 23 references
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Unger M, Frank A. Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction. Rapid Commun Mass Spectrom 2004;1 PubMed
- De Vincenzi M, Silano M, De Vincenzi A, et al. Constituents of aromatic plants: eucalyptol. Fitoterapia 2002;73:269-75. PubMed
- Gray AM, Flatt PR. Antihyperglycemic actions of Eucalyptus globulus (Eucalyptus) are associated with pancreatic and extra-pancreatic effects in mice. J Nutr 1998;128:2319-23. PubMed
- Whitman BW, Ghazizadeh H. Eucalyptus oil: therapeutic and toxic aspects of pharmacology in humans and animals. J Paediatr Child Health 1994;30:190-1. PubMed
- Barker SC and Altman PM. An ex vivo, assessor blind, randomised, parallel group, comparative efficacy trial of the ovicidal activity of three pediculicides after a single application--melaleuca oil and lavender oil, eucalyptus oil and lemon tea tree oil,
- Vilaplana, J. and Romaguera, C. Allergic contact dermatitis due to eucalyptol in an anti-inflammatory cream. Contact Dermatitis 2000;43(2):118.
- Juergens, U. R. [Reducing the need for cortisone. Does eucalyptus oil work in asthma? (interview by Brigitte Moreano]. MMW.Fortschr Med 3-29-2001;143(13):14.
- Tascini, C., Ferranti, S., Gemignani, G., Messina, F., and Menichetti, F. Clinical microbiological case: fever and headache in a heavy consumer of eucalyptus extract. Clin Microbiol.Infect. 2002;8(7):437, 445-437, 446. PubMed
- Galdi, E., Perfetti, L., Calcagno, G., Marcotulli, M. C., and Moscato, G. Exacerbation of asthma related to Eucalyptus pollens and to herb infusion containing Eucalyptus. Monaldi Arch.Chest Dis. 2003;59(3):220-221.
- Spoerke, D. G., Vandenberg, S. A., Smolinske, S. C., Kulig, K., and Rumack, B. H. Eucalyptus oil: 14 cases of exposure. Vet Hum.Toxicol 1989;31(2):166-168.
- Jori, A., Bianchetti, A., Prestini, P. E., and Gerattini, S. Effect of eucalyptol (1,8-cineole) on the metabolism of other drugs in rats and in man. Eur.J Pharmacol 1970;9(3):362-366. PubMed
- Tibballs, J. Clinical effects and management of eucalyptus oil ingestion in infants and young children. Med J Aust 8-21-1995;163(4):177-180. PubMed
- Webb, N. J. and Pitt, W. R. Eucalyptus oil poisoning in childhood: 41 cases in south-east Queensland. J Paediatr.Child Health 1993;29(5):368-371. PubMed
- Gyldenløve M, Menné T, Thyssen JP. Eucalyptus contact allergy. Contact Dermatitis. 2014;71(5):303-304. PubMed
- Higgins C, Palmer A, Nixon R. Eucalyptus oil: contact allergy and safety. Contact Dermatitis. 2015;72(5):344-346. PubMed
- de Groot AC, Schmidt E. Eucalyptus oil and tea tree oil. Contact Dermatitis. 2015;73(6):381-386. PubMed
- Greive KA, Barnes TM. The efficacy of Australian essential oils for the treatment of head lice infestation in children: A randomised controlled trial. Australas J Dermatol. 2018;59(2):e99-e105. PubMed
- Paulsen E, Thormann H, Vestergaard L. Eucalyptus species as a cause of airborne allergic contact dermatitis. Contact Dermatitis. 2018;78(4):301-303.
- Mathew T, John SK, Kamath V, et al. Essential oil related seizures (EORS): A multi-center prospective study on essential oils and seizures in adults. Epilepsy Res. 2021;173:106626. PubMed
- Dudipala SC, Mandapuram P, Ch LK. Eucalyptus Oil-Induced Seizures in Children: Case Reports and Review of the Literature. J Neurosci Rural Pract 2021;12(1):112-115. PubMed
- Panda PK, Sharawat IK, Panda P, Dawman L, Kasinathan A. Clinico-laboratory characteristics and outcome of patients with eucalyptus oil-induced/provoked seizures: A case series and systematic review of the published patients. Trop Doct 2021;51(4):518-522. PubMed
- Sai Chandar D, Prashanthi M, Laxman Kumar C, Amith Kumar C. Eucalyptus Oil-Induced Seizures in Children: A Single-Center Prospective Study. Cureus 2021;13(3):e14109. PubMed
Lemon 2 references
- Ruggenenti P, Caruso MR, Cortinovis M, et al. Fresh lemon juice supplementation for the prevention of recurrent stones in calcium oxalate nephrolithiasis: A pragmatic, prospective, randomised, open, blinded endpoint (PROBE) trial. EClinicalMedicine 2021;4 PubMed
- Umemura K, Katada Y, Nakagawa S, et al. Improved absorption of itraconazole tablet by co-administration with lemon beverages in a lung transplant recipient: A case report. J Infect Chemother 2022;28(8):1203-1207. PubMed
Myrtle 3 references
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Salmanian M, Shirbeigi L, Hashem-Dabaghian F, et al. The Effects of Myrtle (Myrtus communis) and Clindamycin Topical Solution in the Treatment of Mild to Moderate Acne Vulgaris: A Comparative Split-Face Study. J Pharmacopuncture 2020;23(4):220-229.
- Paknejad MS, Eftekhari K, Rahimi R, Vigeh M, Naghizadeh A, Karimi M. Myrtle (Myrtus communis L.) fruit syrup for gastroesophageal reflux disease in children: A double-blind randomized clinical trial. Phytother Res 2021;35(11):6369-6376.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC