Slippery Elm 500 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Slippery Elm 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Slippery Elm 500 mg is a dietary supplement by Puritan's Pride with 1 active ingredient. Its ingredients are commonly taken for sore throat and cough, heartburn and acid reflux, digestive upset and ibs.Based on those ingredients, 2,022 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Slippery Elm 500 mg by Puritan's Pride
Ask about any prescription or over-the-counter medication and we check it for interactions with Slippery Elm 500 mg by Puritan's Pride — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Slippery Elm 500 mg by Puritan's Pride
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient, slippery elm, taken from the inner bark. Its key component is mucilage, the gel-forming substance that is also the basis of the interaction concern described above.
The remaining ingredients are inactive ones that hold the capsule together and fill it out: calcium carbonate, gelatin, vegetable cellulose, silica, and vegetable magnesium stearate.
Does it work?
Couldn't assess
For each condition listed in our data, slippery elm has been rated Insufficient Reliable Evidence To Rate. That covers cancer, constipation, cough, inflammatory bowel disease (IBD), and diarrhea.
In other words, the reliable evidence needed to judge whether it works for these uses isn't established in the data we hold.
How safe is it?
Well-documented data
Slippery elm is generally well tolerated for short-term use, but high-quality safety data are limited. Reported side effects include contact dermatitis (a skin rash from direct contact) and hives (urticaria) after exposure to the bark or its oleoresin, with the pollen noted as an allergen.
In pregnancy, there isn't enough reliable safety data to know either way, and some sources caution against using it. For breastfeeding, there is too little information on safety, so caution is advised.
Talk with your doctor or pharmacist for personalized advice on either situation.
Meds to double-check
Moderate interaction found
Oral drugs (medicines taken by mouth) are the medication type to double-check before taking this product, with a Moderate severity rating. Slippery elm may slow their absorption and lower their levels in the blood.
Confirm your exact medications with your own doctor or pharmacist, and use the search tool on this page to look up specific drugs.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Slippery elm may be of interest if you are looking into it for one of the uses listed above, though the reliable evidence for those uses isn't established. If you take oral medications, be especially careful, since slippery elm may reduce how well they are absorbed.
Pregnancy and breastfeeding call for extra care, so talk it over with your own doctor or pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Slippery Elm 500 mg, straight from the product label.
| Brand | Puritan's Pride |
|---|---|
| Barcode (UPC) | 074312005466 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 24, 2023 |
| DSLD ID | 285981 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Slippery Elm 500 mg by Puritan's Pride, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Slippery Elm | 500 mg | -- |
Other ingredients: Calcium Carbonate, Gelatin, Vegetable Cellulose, Silica, Vegetable Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Puritan’s Pride supplements are produced from the finest raw materials under stringent quality control standards. State-of-the-art manufacturing and packaging facilities ensure you the highest quality nutritional supplements money can buy. When it comes to your health...choose the best.
To reorder item # 21785 www.puritan.com 1-800-645-1030
Precautions
Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Any medication should be taken one (1) hour prior to consuming this product.
Keep out of reach of children.
Do not use if seal under cap is broken or missing.
Storage
Store at room temperature.
Brand IP Statement(s)
Copyright 2019 Puritan’s Pride, Inc.
Seals/Symbols
QA Quality Assured
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: For adults, take one (1) capsule daily, preferably with a meal.
Formulation
No artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no milk, no lactose, no soy, no gluten, no wheat, no yeast, no fish. Sodium free.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Slippery Elm 500 mg by Puritan's Pride label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Slippery Elm 500 mg by Puritan's Pride
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Slippery Elm
Interacts with2,022 drugs
Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated di...
Slippery Elm monograph & interactionsOther (inactive) ingredients: Calcium Carbonate, Gelatin, Vegetable Cellulose, Silica, Vegetable Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Slippery Elm 500 mg by Puritan's Pride Drug Interactions
HelloPharmacist Interaction Report
Slippery Elm 500 mg by Puritan's Pride has documented interactions with medications, through its slippery elm content.
The main one is with oral drugs (medicines taken by mouth), rated Moderate. Slippery elm inner bark contains mucilage, a thick, gel-forming substance that may interfere with how well your body absorbs those drugs, which could lower the amount that reaches your blood.
This is a theoretical concern, but it is worth knowing if you take any daily prescription.
Read the full breakdown — every affected drug type, severity by severity
Oral drugs are the only drug type documented for this product. Altogether, these interactions span 2,023 individual medications.
Because that is a long list, the best move is to look up your exact medications with the search tool on this page, and to confirm anything you find with your own doctor or pharmacist.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Slippery Elm 500 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Slippery Elm 500 mg interact with 2,022 drugs. Click any drug to see the details.
1 of the 1 ingredient in Slippery Elm 500 mg interact with drugs. Each result below shows which ingredient is responsible. Slippery Elm
Carbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carbenicillin Indanyl Sodium interactionCarbetapentane Tannate, Chlorpheniramine TannateTussi-12
How Carbetapentane Tannate, Chlorpheniramine Tannate interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carbetapentane Tannate, Chlorpheniramine Tannate interactionCarbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine TannateQuadratuss, Ry Tuss, Rynatuss, Tri Tannate Plus
How Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interactionCarbetapentane, Chlorpheniramine, PhenylephrineRicotuss
How Carbetapentane, Chlorpheniramine, Phenylephrine interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carbetapentane, Chlorpheniramine, Phenylephrine interactionCarbetapentane, Chlorpheniramine, Phenylephrine, Phenylpropanolamine, Potassium GuaiacolsulfonateCophene-X
How Carbetapentane, Chlorpheniramine, Phenylephrine, Phenylpropanolamine, Potassium Guaiacolsulfonate interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carbetapentane, Chlorpheniramine, Phenylephrine, Phenylpropanolamine, Potassium Guaiacolsulfonate interactionCarbidopaLodosyn
How Carbidopa interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carbidopa interactionCarbidopa, LevodopaDhivy, Rytary, Sinemet, Sinemet CR
How Carbidopa, Levodopa interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carbidopa, Levodopa interactionCarbidopa, Levodopa, EntacaponeStalevo
How Carbidopa, Levodopa, Entacapone interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carbidopa, Levodopa, Entacapone interactionCarbimazoleNeo-Mercazole
How Carbimazole interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carbimazole interactionCarbinoxamine MaleateKarbinal ER
How Carbinoxamine Maleate interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carbinoxamine Maleate interactionCarbinoxamine, PseudoephedrineAndec, Andec TR, Biohist LA, Carbiset, Carbiset-TR, Carbodec +4 more
How Carbinoxamine, Pseudoephedrine interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carbinoxamine, Pseudoephedrine interactionCarbocisteineMucodyne
How Carbocisteine interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carbocisteine interactionCarbol-fuchsinCastellani Paint Modified
How Carbol-fuchsin interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carbol-fuchsin interactionCarboplatinParaplatin
How Carboplatin interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carboplatin interactionCariprazine HydrochlorideVraylar
How Cariprazine Hydrochloride interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Cariprazine Hydrochloride interactionCarisoprodolRela, Soma
How Carisoprodol interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carisoprodol interactionCarmustineBiCNU, Gliadel, Gliadel Wafer
How Carmustine interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carmustine interactionCarphenazineProketazin
How Carphenazine interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carphenazine interactionCarteololCartrol, Ocupress
How Carteolol interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carteolol interactionCarvedilolCoreg, Coreg CR
How Carvedilol interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Carvedilol interactionCasanthranolDoxidan Liquid Gels
How Casanthranol interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Casanthranol interactionCasanthranol, DocusateDoxidan
How Casanthranol, Docusate interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Casanthranol, Docusate interactionCasanthranol, Docusate PotassiumDialose Plus
How Casanthranol, Docusate Potassium interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Casanthranol, Docusate Potassium interactionCasanthranol, Docusate SodiumPeri-Colace
How Casanthranol, Docusate Sodium interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Casanthranol, Docusate Sodium interactionCastor Oil (otc Drug)Purge
How Castor Oil (otc Drug) interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Castor Oil (otc Drug) interactionCedazuridine, DecitabineInqovi
How Cedazuridine, Decitabine interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Cedazuridine, Decitabine interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Cefadroxil interactionCefdinirOmnicef
How Cefdinir interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Slippery Elm 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Cefditoren Pivoxil interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Slippery Elm 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Slippery Elm
Oral Drugs
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.
Brand information
Manufacturer and brand details for Slippery Elm 500 mg, from the product label.
Puritan's Pride
See all Puritan's Pride products- Name
- Puritan's Pride, Inc.
- City
- Ronkonkoma
- State
- NY
- ZipCode
- 11779
- Phone Number
- 1-800-645-1030
- Web Address
- www.puritan.com
Slippery Elm 500 mg by Puritan's Pride: Common Questions
Does Slippery Elm 500 mg by Puritan's Pride interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is slippery elm safe to take during pregnancy?
What side effects can slippery elm cause?
Does slippery elm work for constipation or diarrhea?
What is slippery elm in this product for?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Slippery Elm 500 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Slippery Elm 500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Slippery Elm 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Slippery Elm 3 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC