Slippery Elm Bark Ingredients & Drug Interactions
by Pure Herbs
What is this page for?
First and foremost: checking Slippery Elm Bark against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Slippery Elm Bark is a dietary supplement by Pure Herbs with 1 active ingredient. Its ingredients are commonly taken for sore throat and cough, heartburn and acid reflux, digestive upset and ibs.Based on those ingredients, 2,022 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm Inner Bark Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Slippery Elm Bark by Pure Herbs
Ask about any prescription or over-the-counter medication and we check it for interactions with Slippery Elm Bark by Pure Herbs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Slippery Elm Bark by Pure Herbs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This liquid contains one active ingredient: slippery elm inner bark extract. The product has no inactive fillers or other ingredients listed.
Does it work?
Not established
The evidence for slippery elm isn't established in the data we hold. We list insufficient reliable evidence for cancer, constipation, cough, inflammatory bowel disease (IBD), and diarrhea.
That doesn't mean it doesn't work — it means the clinical research so far isn't strong enough to say either way.
How safe is it?
Well-documented data
Slippery elm is generally well tolerated for short-term use, but good quality safety data are limited. The pollen and the bark itself can trigger allergic reactions in some people — contact dermatitis (an itchy rash from skin contact) and urticaria (hives) have been reported.
There isn't enough data to know whether it's safe during pregnancy or breastfeeding, so talk with your doctor or pharmacist about it if either applies to you.
Meds to double-check
Moderate interaction found
Oral drugs (prescription and over-the-counter) may be absorbed more slowly and reach lower levels in your bloodstream. Use the medication search tool on this page to check your exact medications before starting.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Slippery Elm Bark is one to take an extra moment with if you're on oral medications, because the mucilage in it may interfere with how your body absorbs them. Check your exact medications using the tool on this page before you start.
If you're pregnant or nursing, discuss it with your doctor or pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Slippery Elm Bark, straight from the product label.
| Brand | Pure Herbs |
|---|---|
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Dec 13, 2022 |
| DSLD ID | 278847 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Slippery Elm Bark by Pure Herbs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Slippery Elm Inner Bark Extract | 1934 mg | -- |
Other ingredients: None
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: For adults, mix 2 mL (abt. 1/2 tsp) of extract in 2 fl. oz (60 mL) water one time daily preferably with a meal.
Shake well before use
Formulation
Helps to support a healthy gastrointestinal tract.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Warning: Not intended for use by pregnant or nursing women. If you have a medical condition or are taking medication, consult your doctor prior to use.
Discontinue use and consult with your doctor if any adverse reactions occur.
Keep out of reach of children
Brand IP Statement(s)
Pure Herbs, Ltd. Natural Herbal Extracts
FDA Statement of Identity
Dietary Supplement
General Statements
"No expense has been spared to provide the finest nature has to offer."
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Slippery Elm Bark by Pure Herbs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Slippery Elm Bark by Pure Herbs
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 mL Dosage formLiquid Servings per container15 Amounts shown are per serving.
Slippery Elm Inner Bark Extract
Interacts with2,022 drugs
Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated di...
Slippery Elm Inner Bark Extract monograph & interactionsOther (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.
Slippery Elm Bark by Pure Herbs Drug Interactions
HelloPharmacist Interaction Report
Slippery Elm Bark by Pure Herbs contains slippery elm inner bark extract, which has a documented interaction with oral drugs — the supplement's mucilage (a thick, gel-like substance) may slow how your body absorbs medications taken by mouth and lower the amount that reaches your bloodstream.
This is a Moderate severity concern.
Read the full breakdown — every affected drug type, severity by severity
Because slippery elm could potentially affect so many oral medications, you'll want to check your exact drugs using the search tool on this page before you start. If you take any prescription or over-the-counter oral medications — pills, capsules, or liquids — run them through to see if a timing gap or dose adjustment might be needed.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Slippery Elm Bark?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Slippery Elm Bark interact with 2,022 drugs. Click any drug to see the details.
1 of the 1 ingredient in Slippery Elm Bark interact with drugs. Each result below shows which ingredient is responsible. Slippery Elm Inner Bark Extract
"phentolamineOraVerse, Rogitine, Ryzumvi
How "phentolamine interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + "phentolamine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + 6-mercaptopurine interactionAbacavirZiagen
How Abacavir interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Abacavir interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acalabrutinib interactionAcamprosateCampral
How Acamprosate interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acamprosate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Slippery Elm Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Acetaminophen, Caffeine, Isometheptene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Slippery Elm Bark with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Slippery Elm Inner Bark Extract
Oral Drugs
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.
Brand information
Manufacturer and brand details for Slippery Elm Bark, from the product label.
Pure Herbs
See all Pure Herbs products- Name
- Pure Herbs, Ltd.
- City
- Sterling Heights
- State
- MI
- Phone Number
- (800) 860-4372
- Web Address
- www.pureherbs.com
Slippery Elm Bark by Pure Herbs: Common Questions
Does Slippery Elm Bark by Pure Herbs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take slippery elm at the same time as my other pills?
Will this help my digestive issues?
What if I'm allergic to pollen or tree products?
Is it safe if I'm pregnant or breastfeeding?
How long can I safely use this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Slippery Elm Bark is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Slippery Elm Bark’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Slippery Elm Bark's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Slippery Elm 3 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC