Slippery Elm Ingredients & Drug Interactions
by New Sun
What is this page for?
First and foremost: checking Slippery Elm against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Slippery Elm is a dietary supplement by New Sun with 1 active ingredient. Its ingredients are commonly taken for sore throat and cough, heartburn and acid reflux, digestive upset and ibs.Based on those ingredients, 2,022 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Slippery Elm by New Sun
Ask about any prescription or over-the-counter medication and we check it for interactions with Slippery Elm by New Sun — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Slippery Elm by New Sun
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: slippery elm inner bark, a demulcent herb traditionally used to soothe mucous membranes. The capsule is made with gelatin as an inactive ingredient.
Does it work?
Couldn't assess
The evidence for slippery elm isn't established in our data. We hold insufficient reliable evidence to rate it for constipation, diarrhea, cough, inflammatory bowel disease (IBD), or cancer.
That doesn't mean it doesn't work — it means the clinical trials we have don't give us a clear answer yet.
How safe is it?
Well-documented data
Slippery elm is generally well tolerated for short-term use, though high-quality safety data are limited. The main concern is allergic reactions: the pollen is an allergen, and contact dermatitis and skin hives have been reported after exposure to slippery elm or compounds in the bark.
If you have a known tree pollen allergy or sensitive skin, be cautious. Not enough reliable safety data exist to determine whether it's safe during pregnancy or breastfeeding.
If you're pregnant or breastfeeding and considering this supplement, talk with your doctor or pharmacist about whether it's right for you.
Meds to double-check
Moderate interaction found
Any oral medication you take — prescription, over-the-counter, or otherwise — may be absorbed more slowly when combined with slippery elm due to its Moderate interaction with oral drugs. Ask your doctor or pharmacist to review your specific medicines and advise on spacing or whether this product is safe for you.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Slippery elm may be worth considering if you're looking for a traditional throat or digestive soother — but the evidence for specific conditions isn't strong yet. The key concern is that it can slow how your body absorbs oral medications, affecting over 2,000 different drugs.
Before you start, check your exact medications with your own doctor or pharmacist and confirm safe timing between doses.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 1, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Slippery Elm, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Slippery Elm by New Sun, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Warning: If you are pregnant, nursing, taking any medications, or experiencing health issues, consult your doctor before use.
Do not use if safety seal is missing or broken.
Keep out of reach of children.
General
Product No. 69-8 V3.0
FDA Statement of Identity
Dietary Supplement
Formulation
This product does not contain: yeast, corn, wheat, egg, starch, preservatives, artificial coloring or sweeteners.
Suggested/Recommended/Usage/Directions
Recommendation: As a dietary supplement, take two capsules with meals twice daily.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Slippery Elm by New Sun label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Slippery Elm by New Sun
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.
Slippery Elm
Interacts with2,022 drugs
Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated di...
Slippery Elm monograph & interactionsOther (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.
Slippery Elm by New Sun Drug Interactions
HelloPharmacist Interaction Report
Slippery Elm by New Sun may slow how your body absorbs oral medications, potentially reducing their effectiveness.
The inner bark contains a substance called mucilage that can interfere with drug absorption in the digestive tract, affecting a broad range of oral medications.
Read the full breakdown — every affected drug type, severity by severity
This is a Moderate-severity interaction. Because slippery elm's mucilage can coat the digestive lining and slow absorption, timing matters: taking your medications and this supplement several hours apart may help, but you'll want to confirm the spacing with your own doctor or pharmacist for each drug you take.
Altogether, these interactions span 2,023 individual medications.
If you take any oral medication — whether a prescription, over-the-counter pill, or capsule — run it through the interaction checker below before you start slippery elm. Your doctor or pharmacist can advise on safe spacing or whether this product is right for you alongside your current regimen.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Slippery Elm?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Slippery Elm interact with 2,022 drugs. Click any drug to see the details.
1 of the 1 ingredient in Slippery Elm interact with drugs. Each result below shows which ingredient is responsible. Slippery Elm
Amlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Ammonium Chloride interactionAmobarbitalAmytal
How Amobarbital interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amobarbital interactionAmobarbital, SecobarbitalTuinal
How Amobarbital, Secobarbital interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amobarbital, Secobarbital interactionAmoxapineAsendin
How Amoxapine interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amoxapine interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphetamineAdensys XR-ODT, Adzenys ER, Dyanavel XR, Mydayis
How Amphetamine interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amphetamine interactionAmphetamine Aspartate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine SulfateAdderall, Adderall XR
How Amphetamine Aspartate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amphetamine Aspartate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate interactionAmphetamine SulfateBenzedrine, Evekeo ODT
How Amphetamine Sulfate interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amphetamine Sulfate interactionAmphotericin BAbelcet, AmBisome, Amphocil, Amphocin, Fungizone IV
How Amphotericin B interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amphotericin B interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Ampicillin interactionAmprenavirAgenerase
How Amprenavir interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amprenavir interactionAmylase, Lipase, ProteaseDigepepsin, Entozyme, Festal II, Ilozyme, Ku-Zyme, Ku-Zyme HP +21 more
How Amylase, Lipase, Protease interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amylase, Lipase, Protease interactionAmylase, Lipase, Protease (prescription Drug)Pancreatin 10, Pancron 10 Pancreatin
How Amylase, Lipase, Protease (prescription Drug) interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Amylase, Lipase, Protease (prescription Drug) interactionAnagrelideAgrylin
How Anagrelide interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Anagrelide interactionAnastrozoleArimidex
How Anastrozole interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Anastrozole interactionAnisindioneMiradon
How Anisindione interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntispasmodic, Combination EnzymeDonnazyme
How Antispasmodic, Combination Enzyme interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Antispasmodic, Combination Enzyme interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Antithrombin Iii interactionApalutamideErleada
How Apalutamide interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Apalutamide interactionApixabanEliquis
How Apixaban interacts with Slippery Elm — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Apixaban interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Slippery Elm with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Slippery Elm
Oral Drugs
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.
Brand information
Manufacturer and brand details for Slippery Elm, from the product label.
New Sun
See all New Sun products- Name
- New Sun
- City
- Hendersonville
- State
- NC
- ZipCode
- 28792
- Phone Number
- 1-800-544-0777
- Web Address
- www.newsun.net
Slippery Elm by New Sun: Common Questions
Does Slippery Elm by New Sun interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will slippery elm work for my constipation or diarrhea?
Can I take slippery elm at the same time as my other pills?
Is slippery elm safe if I have a tree pollen allergy?
Can I use slippery elm while I'm pregnant or breastfeeding?
What's in this capsule besides slippery elm?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Slippery Elm is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Slippery Elm’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Slippery Elm's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Slippery Elm 3 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC