Slippery Elm Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Slippery Elm Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Slippery Elm Extract is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for sore throat and cough, heartburn and acid reflux, digestive upset and ibs.Based on those ingredients, 2,022 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm Bark Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Slippery Elm Extract by BulkSupplements.com
Ask about any prescription or over-the-counter medication and we check it for interactions with Slippery Elm Extract by BulkSupplements.com — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Slippery Elm Extract by BulkSupplements.com
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: slippery elm bark extract. Slippery elm is derived from the inner bark of the slippery elm tree and has been used traditionally to soothe the digestive tract.
There are no other active ingredients, and no inactive fillers or binders are listed.
Does it work?
Couldn't assess
The evidence for slippery elm's effectiveness isn't established in our data. The facts we hold show insufficient reliable evidence to rate it for cancer, constipation, cough, inflammatory bowel disease (IBD), and diarrhea — the conditions it's commonly used for.
That doesn't mean it doesn't work; it means rigorous clinical trials haven't yet confirmed what it can or can't do.
How safe is it?
Well-documented data
Slippery elm extract is generally well tolerated for short-term use, but high-quality safety data are limited — we don't have a lot of good research on long-term safety. Topically, it can cause contact dermatitis (skin irritation) and urticaria (hives), and the pollen is an allergen, so avoid it if you're allergic to elm or experience reactions to it.
For pregnancy, not enough reliable safety data exist — some sources caution against it, so talk with your doctor or pharmacist before using it during pregnancy. Similarly, there's too little information on safety while breastfeeding, so caution is advised if you're nursing.
Meds to double-check
Moderate interaction found
Check all your oral medications before taking this product — slippery elm may slow their absorption. With 2,003 individual drugs potentially affected, using the medication checker below is essential.
If you can't separate doses by two hours, ask your pharmacist about whether slippery elm is right for you.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Slippery elm may be worth considering if you're interested in traditional digestive support, but the evidence for specific benefits hasn't been firmly established. The main concern is that it could slow how your body absorbs oral medications.
Check your exact drugs with the tool on this page before starting, separate any medications from this supplement by at least two hours, and talk with your pharmacist if you're pregnant, nursing, or have an elm allergy.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Slippery Elm Extract, straight from the product label.
| Brand | BulkSupplements.com |
|---|---|
| Barcode (UPC) | X001A16NN7 |
| Net contents | 100 Gram(s); 3.5 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Jun 20, 2024 |
| DSLD ID | 311562 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Slippery Elm Extract by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Slippery Elm Bark Extract | 750 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
BulkSupplements.com Clean & Pure Bulk Supplements
Formulation
Color may vary
Free of: Added sugar, soy, dairy, yeast, gluten, additives
FDA Disclaimer Statement
Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Always consult a physician before taking any dietary supplement.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take 750 mg (about 1/3 tsp) once daily, or as directed by a physician.
Storage
Store in a dry, cool place
General Statements
Use an accurate milligram scale. Contents are sold by weight, not volume. Settling may occur. New
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Slippery Elm Extract by BulkSupplements.com label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Slippery Elm Extract by BulkSupplements.com
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size750 mg Dosage formPowder Servings per container133 Amounts shown are per serving.
Slippery Elm Bark Extract
Interacts with2,022 drugs
Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated di...
Slippery Elm Bark Extract monograph & interactionsSlippery Elm Extract by BulkSupplements.com Drug Interactions
HelloPharmacist Interaction Report
Slippery Elm Extract by BulkSupplements.com contains one active ingredient — slippery elm bark extract — which has a documented Moderate interaction with oral medications.
The extract's mucilage (a thick, gummy substance) may coat your digestive tract and slow how quickly your body absorbs drugs taken by mouth, potentially lowering their blood levels and reducing how well they work.
Read the full breakdown — every affected drug type, severity by severity
Altogether, these interactions span 2,003 individual medications. Because so many oral drugs could be affected, you'll want to check your exact prescriptions and over-the-counter medications using the search tool on this page before you start slippery elm.
As a general rule, separate any oral medication from this supplement by at least two hours — take your drugs first, then slippery elm later (or vice versa) — and let your pharmacist know you're considering it.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Slippery Elm Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Slippery Elm Extract interact with 2,022 drugs. Click any drug to see the details.
1 of the 1 ingredient in Slippery Elm Extract interact with drugs. Each result below shows which ingredient is responsible. Slippery Elm Bark Extract
"phentolamineOraVerse, Rogitine, Ryzumvi
How "phentolamine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + "phentolamine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + 6-mercaptopurine interactionAbacavirZiagen
How Abacavir interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abacavir interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acalabrutinib interactionAcamprosateCampral
How Acamprosate interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acamprosate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Caffeine, Isometheptene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Slippery Elm Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Slippery Elm Bark Extract
Oral Drugs
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.
Brand information
Manufacturer and brand details for Slippery Elm Extract, from the product label.
BulkSupplements.com
See all BulkSupplements.com products- Name
- BulkSupplements.com
- Street Address
- 7511 Eastgate Rd
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Web Address
- BulkSupplements.com
Slippery Elm Extract by BulkSupplements.com: Common Questions
Does Slippery Elm Extract by BulkSupplements.com interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does slippery elm really work for digestion or IBD?
Can I take slippery elm with my other medications?
Is slippery elm safe while I'm pregnant?
What about breastfeeding?
Can slippery elm cause allergic reactions?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Slippery Elm Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Slippery Elm Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Slippery Elm Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Slippery Elm 3 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC