Slippery Elm Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Slippery Elm Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Slippery Elm Extract is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for sore throat and cough, heartburn and acid reflux, digestive upset and ibs.Based on those ingredients, 2,022 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm Bark Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Slippery Elm Extract by BulkSupplements.com
Ask about any prescription or over-the-counter medication and we check it for interactions with Slippery Elm Extract by BulkSupplements.com — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Slippery Elm Extract by BulkSupplements.com
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Slippery Elm Bark Extract. Slippery elm has been used traditionally to soothe the digestive tract, though the evidence supporting its effectiveness for specific conditions remains limited.
Does it work?
Couldn't assess
The evidence we hold on slippery elm is incomplete. We don't have reliable data to rate whether it works for cancer, constipation, cough, inflammatory bowel disease, or diarrhea.
If you're considering it for a particular reason, talk with your pharmacist or doctor about what the broader research shows and whether it's a good fit for your situation.
How safe is it?
Well-documented data
Slippery elm is generally well tolerated when used short-term, but high-quality safety studies are limited. Topically, it can cause contact dermatitis (skin irritation) in some people, and the pollen is a known allergen—contact dermatitis and hives have been reported after exposure to slippery elm or compounds in the bark.
There isn't enough reliable data to know whether slippery elm is safe during pregnancy or breastfeeding. If you're pregnant or nursing, talk with your doctor or pharmacist before starting it.
Meds to double-check
Moderate interaction found
Before you start, check any oral medications you take—this product may reduce their absorption and lower their effectiveness. Because the interaction affects a large number of oral drugs, it's important to review your specific prescriptions and over-the-counter medications with your pharmacist.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Slippery elm may be worth a try if you're looking for digestive support, but the evidence for most conditions is still being sorted out. The main thing to watch: it can interfere with how your body absorbs oral medications.
If you take any regular medications, check them first—and space doses a few hours apart if possible.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Slippery Elm Extract, straight from the product label.
| Brand | BulkSupplements.com |
|---|---|
| Barcode (UPC) | X001A3DK09 |
| Net contents | 250 Gram(s); 8.8 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Jun 20, 2024 |
| DSLD ID | 311563 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Slippery Elm Extract by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Slippery Elm Bark Extract | 750 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
BulkSupplements.com Clean & Pure Bulk Supplements
Formulation
Color may vary
Free of: Added sugar, soy, dairy, yeast, gluten, additives
FDA Disclaimer Statement
Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Always consult a physician before taking any dietary supplement.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take 750 mg (about 1/3 tsp) once daily, or as directed by a physician.
Storage
Store in a dry, cool place
General Statements
Use an accurate milligram scale. Contents are sold by weight, not volume. Settling may occur. New
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Slippery Elm Extract by BulkSupplements.com label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Slippery Elm Extract by BulkSupplements.com
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size750 mg Dosage formPowder Servings per container333 Amounts shown are per serving.
Slippery Elm Bark Extract
Interacts with2,022 drugs
Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated di...
Slippery Elm Bark Extract monograph & interactionsSlippery Elm Extract by BulkSupplements.com Drug Interactions
HelloPharmacist Interaction Report
Slippery Elm Extract by BulkSupplements.com may slow how your body absorbs oral medications.
The inner bark contains a substance called mucilage that can coat your digestive tract and interfere with drug absorption, potentially lowering the levels of medication in your blood. This is a moderate interaction affecting oral drugs.
Read the full breakdown — every affected drug type, severity by severity
Because slippery elm can reduce how much of your medication your body actually takes in, drugs that need reliable absorption to work well—or to keep you safe—may become less effective. This is especially important if you take medications with a narrow therapeutic window (where the dose has to be just right).
Altogether, these interactions span 2,003 individual medications.
If you take any oral prescription or over-the-counter medication, check your exact drugs with the search tool on this page before starting slippery elm. Timing matters too: separating your doses by a few hours may help, but ask your pharmacist for a dosing plan tailored to your specific medications.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Slippery Elm Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Slippery Elm Extract interact with 2,022 drugs. Click any drug to see the details.
1 of the 1 ingredient in Slippery Elm Extract interact with drugs. Each result below shows which ingredient is responsible. Slippery Elm Bark Extract
"phentolamineOraVerse, Rogitine, Ryzumvi
How "phentolamine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + "phentolamine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + 6-mercaptopurine interactionAbacavirZiagen
How Abacavir interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abacavir interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acalabrutinib interactionAcamprosateCampral
How Acamprosate interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acamprosate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Slippery Elm Extract — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Caffeine, Isometheptene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Slippery Elm Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Slippery Elm Bark Extract
Oral Drugs
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.
Brand information
Manufacturer and brand details for Slippery Elm Extract, from the product label.
BulkSupplements.com
See all BulkSupplements.com products- Name
- BulkSupplements.com
- Street Address
- 7511 Eastgate Rd
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Web Address
- BulkSupplements.com
Slippery Elm Extract by BulkSupplements.com: Common Questions
Does Slippery Elm Extract by BulkSupplements.com interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take slippery elm if I'm on other medications?
Is slippery elm safe to use while pregnant?
Can I take slippery elm while breastfeeding?
What is slippery elm actually used for?
Does slippery elm have any side effects?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Slippery Elm Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Slippery Elm Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Slippery Elm Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Slippery Elm 3 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC