Slippery Elm Select Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Slippery Elm Select against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Slippery Elm Select is a dietary supplement by Moss Nutrition with 2 active ingredients. Its ingredients are commonly taken for osteoarthritis joint pain, rheumatoid arthritis, inflammation.Based on those ingredients, 2,161 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm bark powder, Boswellia Gum Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Slippery Elm Select by Moss Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with Slippery Elm Select by Moss Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Slippery Elm Select by Moss Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Slippery Elm Select contains two active ingredients: Boswellia gum extract — a resin from the boswellia tree traditionally used in Indian and Middle Eastern medicine — and slippery elm bark powder, the inner bark of the slippery elm tree ground into powder form. Slippery elm's characteristic mucilage is what gives it its soothing texture.
There are no other active ingredients; the product contains no fillers or added inactive ingredients beyond what's listed here.
Does it work?
Moderate evidence
Evidence for Boswellia is fairly mixed. It's possibly effective for osteoarthritis, but there isn't enough reliable evidence yet to say whether it helps hay fever, Alzheimer disease, asthma, or cluster headache.
For slippery elm, the data we hold shows insufficient evidence to rate it for cancer, constipation, cough, inflammatory bowel disease, or diarrhea — so we don't yet know whether it's effective for these uses based on the research available to us.
How safe is it?
Well-documented data
Both ingredients are generally well tolerated for short-term use, though quality and dose vary widely between products, so what works in one brand may not be the same in another. Boswellia's most common side effects are stomach upset — abdominal pain, diarrhea, nausea, heartburn — plus headache and itching.
In rare cases, large amounts of boswellia gum resin can form a bezoar (a hard mass in your stomach). Slippery elm pollen can trigger contact dermatitis or hives in people with allergies.
The safety data for both ingredients during pregnancy and breastfeeding are limited; the facts note caution during pregnancy for slippery elm and advise avoiding Boswellia during pregnancy and breastfeeding. Talk with your doctor or pharmacist about whether either ingredient is appropriate for you if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you take any medications metabolized by your liver — that includes many antidepressants, blood pressure drugs, blood thinners, pain relievers, and heart medications. Boswellia may increase their levels in your bloodstream, making them stronger.
Also double-check if you're on immunosuppressive drugs (such as those for autoimmune conditions or after transplant) or any oral medications: slippery elm may slow how your body absorbs them.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Slippery Elm Select may appeal to you if you're looking to ease digestive or throat discomfort and want to try a traditional herbal combination. But because Boswellia can affect how your body breaks down many medications, you'll need to check your specific prescriptions and over-the-counter drugs with your doctor or pharmacist before starting — especially if you take heart, blood pressure, antidepressant, or immunosuppressant medications.
The evidence that either ingredient works for most conditions isn't strong yet, so manage your expectations. A quick conversation with your own healthcare provider will help you decide if it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Slippery Elm Select, straight from the product label.
| Brand | Moss Nutrition |
|---|---|
| Barcode (UPC) | M134 |
| Net contents | 166 Gram(s); 5.8 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2022 |
| DSLD ID | 275545 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Slippery Elm Select by Moss Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Boswellia Gum Extract | 1110 mg | -- |
| Slippery Elm bark powder | 2590 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: 1 scoop per day in divided doses, AM & PM, or as directed by your healthcare professional. Either sprinkle on food, add to shake, or mix with water or juice, allow to thicken for 15 minutes & drink as a slurry.
Stir gently prior to use.
General Statements
Contents may settle.
Precautions
Warning: If you are taking medication, have a medical condition or an upcoming medical procedure, or are pregnant or nursing, consult a physician before using.
If adverse reactions occur, discontinue use & consult your healthcare practitioner.
Keep out of reach of children.
Brand IP Statement(s)
Moss Nutrition M Professional Supplements Est. 1991
Formula
Slippery Elm Select With standardized Boswellia extract
FDA Statement of Identity
Dietary Supplement
Formulation
Does not contain gluten.
Storage
Store sealed in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Slippery Elm Select by Moss Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Slippery Elm Select by Moss Nutrition
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size3.7 Gram(s) Dosage formPowder Servings per container45 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Boswellia Gum Extract
Interacts with952 drugs
Boswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation. Some studies suggest it may help with osteoart...
Boswellia Gum Extract monograph & interactionsSlippery Elm bark powder
Interacts with2,022 drugs
Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated di...
Slippery Elm bark powder monograph & interactionsSlippery Elm Select by Moss Nutrition Drug Interactions
HelloPharmacist Interaction Report
Slippery Elm Select by Moss Nutrition contains two active ingredients — Boswellia gum extract and slippery elm bark powder — and both have documented interactions with medications.
The most serious concern comes from Boswellia's effect on your liver enzymes (CYP2D6, CYP2C19, CYP1A2, CYP2C9, and CYP3A4 substrates): this ingredient may increase the levels of drugs that depend on those enzymes to break down, potentially making those medications stronger or longer-acting than intended. Altogether, these interactions span 2,162 individual medications.
Read the full breakdown — every affected drug type, severity by severity
Boswellia also theoretically may alter how immunosuppressive drugs (medications that dampen your immune system) work, though the exact effect isn't certain. Slippery elm's mucilage — the gummy texture that soothes your throat — can slow how quickly your body absorbs oral medications, which may reduce their effectiveness.
If you take any prescription or over-the-counter medication, especially antidepressants, blood pressure medications, blood thinners, heart drugs, or immunosuppressants, run your specific medications through the interaction checker below before starting this product. Your doctor or pharmacist can tell you whether the timing or dose of your current drugs needs adjusting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Slippery Elm Select?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Slippery Elm Select interact with 2,161 drugs. Click any drug to see the details.
2 of the 2 ingredients in Slippery Elm Select interact with drugs. Each result below shows which ingredient is responsible. Slippery Elm bark powder Boswellia Gum Extract
AstemizoleHismanal
How Astemizole interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Astemizole interactionAtazanavirReyataz
How Atazanavir interacts with Slippery Elm Select — through 2 ingredients. Tap an ingredient for the detail:
Boswellia Gum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Boswellia Gum Extract + Atazanavir interactionSlippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atazanavir interactionAtazanavir, CobicistatEvotaz
How Atazanavir, Cobicistat interacts with Slippery Elm Select — through 2 ingredients. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atazanavir, Cobicistat interactionBoswellia Gum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Boswellia Gum Extract + Atazanavir, Cobicistat interactionAtenololAtenix, Tenormin
How Atenolol interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atenolol, Chlorthalidone interactionAtezolizumabTecentriq
How Atezolizumab interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Boswellia Gum ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, Boswellia serrata might alter the effects of immunosuppressive drugs.
Read the full Boswellia Gum Extract + Atezolizumab interactionAtogepantQulipta
How Atogepant interacts with Slippery Elm Select — through 2 ingredients. Tap an ingredient for the detail:
Boswellia Gum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Boswellia Gum Extract + Atogepant interactionSlippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atogepant interactionAtomoxetineStrattera
How Atomoxetine interacts with Slippery Elm Select — through 2 ingredients. Tap an ingredient for the detail:
Boswellia Gum ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Boswellia Gum Extract + Atomoxetine interactionSlippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atomoxetine interactionAtorvastatinAtorvaliq
How Atorvastatin interacts with Slippery Elm Select — through 2 ingredients. Tap an ingredient for the detail:
Boswellia Gum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Boswellia Gum Extract + Atorvastatin interactionSlippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atorvastatin interactionAtorvastatin CalciumLipitor
How Atorvastatin Calcium interacts with Slippery Elm Select — through 2 ingredients. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atorvastatin Calcium interactionBoswellia Gum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Boswellia Gum Extract + Atorvastatin Calcium interactionAtovaquoneMepron
How Atovaquone interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atovaquone interactionAtovaquone, ProguanilMalarone
How Atovaquone, Proguanil interacts with Slippery Elm Select — through 2 ingredients. Tap an ingredient for the detail:
Boswellia Gum ExtractCytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2C19 substrates.
Read the full Boswellia Gum Extract + Atovaquone, Proguanil interactionSlippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atovaquone, Proguanil interactionAtropineSal-Tropine
How Atropine interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atropine interactionAtropine Methyl Nitrate, Digestive EnzymesFestalan
How Atropine Methyl Nitrate, Digestive Enzymes interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atropine Methyl Nitrate, Digestive Enzymes interactionAtropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, PhenylAtrosept
How Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl interactionAtropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl SalicylateUrinary Antiseptic 2, Urised
How Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl Salicylate interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atropine, Benzoic Acid, Hyoscyamine, Methenamine, Methylene Blue, Phenyl Salicylate interactionAtropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, ScopolamineAtrohist Plus, Pro Tuss, Ru-tuss, Stahist
How Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interacts with Slippery Elm Select — through 2 ingredients. Tap an ingredient for the detail:
Boswellia Gum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Boswellia Gum Extract + Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interactionSlippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interactionAtropine, DifenoxinMotofen
How Atropine, Difenoxin interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atropine, Difenoxin interactionAtropine, DiphenoxylateLofene, Lomotil
How Atropine, Diphenoxylate interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atropine, Diphenoxylate interactionAtropine, Hyoscyamine, PhenobarbitalHypnaldyne
How Atropine, Hyoscyamine, Phenobarbital interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atropine, Hyoscyamine, Phenobarbital interactionAtropine, Hyoscyamine, Phenobarbital, ScopolamineBarbidonna No. 2, Belladonna Phenobarbital
How Atropine, Hyoscyamine, Phenobarbital, Scopolamine interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atropine, Hyoscyamine, Phenobarbital, Scopolamine interactionAtropine, Hyoscyamine, ScopolamineColytrol
How Atropine, Hyoscyamine, Scopolamine interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atropine, Hyoscyamine, Scopolamine interactionAtropine, Hyoscyamine, Scopolamine, PhenobarbitalBarbeloid, Donnatal #2, Donphen
How Atropine, Hyoscyamine, Scopolamine, Phenobarbital interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atropine, Hyoscyamine, Scopolamine, Phenobarbital interactionAtropine, PhenobarbitalAnthrocol
How Atropine, Phenobarbital interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Atropine, Phenobarbital interactionAtropine, MeperidineAtropine, Meperidine
How Atropine, Meperidine interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Boswellia Gum ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Boswellia Gum Extract + Atropine, Meperidine interactionAtropine, Morphine SulfateAtropine, Morphine Sulfate
How Atropine, Morphine Sulfate interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Boswellia Gum ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Boswellia Gum Extract + Atropine, Morphine Sulfate interactionAttapulgiteKaopectate (Canada)
How Attapulgite interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Attapulgite interactionAuranofinRidaura
How Auranofin interacts with Slippery Elm Select — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Auranofin interactionAvacopanTavneos
How Avacopan interacts with Slippery Elm Select — through 2 ingredients. Tap an ingredient for the detail:
Boswellia Gum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Boswellia Gum Extract + Avacopan interactionSlippery Elm Bark PowderOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Powder + Avacopan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Slippery Elm Select with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Slippery Elm bark powder
Oral Drugs
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.
Boswellia Gum Extract
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP1A2 enzymes.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Boswellia serrata might increase the levels of CYP2C19 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C19 enzymes.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, Boswellia serrata might increase the levels of CYP2C9 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C9 enzymes.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2D6 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP3A4 enzymes. Other in vitro research shows that Boswellia serrata extract inhibits CYP3A4 enzymes at most concentrations, although it may modestly induce enzyme activity at low concentrations.
Immunosuppressants
Theoretically, Boswellia serrata might alter the effects of immunosuppressive drugs.
Some in vitro research suggests that Boswellia serrata extracts might inhibit mediators of autoimmune disorders such as leukotrienes and reduce production of antibodies and cell-mediated immunity. However, other in vitro research suggests that, when coupled with calcium ions, boswellic acids containing the keto group have immunostimulant properties within specific cell signaling pathways.
Brand information
Manufacturer and brand details for Slippery Elm Select, from the product label.
Moss Nutrition
See all Moss Nutrition products- Name
- Moss Nutrition Products, Inc.
- Street Address
- 380 Russell Street
- City
- Hadley
- State
- MA
- ZipCode
- 01035
- Phone Number
- 800-851-5444
- Web Address
- www.mossnutrition.com
Slippery Elm Select by Moss Nutrition: Common Questions
Does Slippery Elm Select by Moss Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm pregnant or breastfeeding?
What side effects might I notice?
Does slippery elm actually work for digestive issues?
What is Boswellia used for in this product?
Why do I need to check my medications before taking this?
Can slippery elm interfere with my other drugs?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Slippery Elm Select is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Slippery Elm Select’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Boswellia Serrata
Interacts with 952 drugsBoswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation. Some studies suggest it may help with osteoarthritis symptoms, but the overall evidenc...
Read the full Boswellia Serrata monograph → Herb & supplement monographSlippery Elm
Interacts with 2,022 drugsSlippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated digestive tracts. Its mucilage can coat an...
Read the full Slippery Elm monograph →Sources & How We Checked
Slippery Elm Select's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 19 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Boswellia Serrata 16 references
- Gupta I, Gupta V, Parihar A, et al. Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study. Eur J Med Res 1998;3:511-4.
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Kimmatkar N, Thawani V, Hingorani L, et al. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine 2003;10:3-7. PubMed
- Liu JJ, Nilsson A, Oredsson S, et al. Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. Carcinogenesis 2002;23:2087-93. PubMed
- Wildfeuer A, Neu IS, Safayhi H, et al. Effects of boswellic acids extracted from a herbal medicine on the biosynthesis of leukotrienes and the course of experimental autoimmune encephalomyelitis. Arzneimittelforschung 1998;48:668-74.
- Gupta I, Parihar A, Malhotra P, et al. Effects of gum resin of Boswellia serrata in patients with chronic colitis. Planta Med 2001;67:391-5. PubMed
- Sengupta K, Alluri KV, Satish AR, et al. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin. Arthritis Res Ther 2008;10:R85.
- Sengupta K, Krishnaraju AV, Vishal AA, et al. Comparative efficacy and tolerability of 5-Loxin and Aflapin against osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study. Int J Med Sci 2010;7:366-77.
- Ernst E. Frankincense: systematic review. BMJ 2008;337:a2813. PubMed
- Kirste S, Treier M, Wehrle SJ, et al. Boswellia serratea extract acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial. Cancer 2011;117:3788-95.
- Frank A, Unger M. Analysis of frankincense from various Boswellia species with inhibitory activity on human drug metabolising cytochrome P450 enzymes using liquid chromatography mass spectrometry after automated on-line extraction. J Chromatogr A 2006;111 PubMed
- Altmann A, Poeckel D, Fischer L, et al. Coupling of boswellic acid-incuded Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes. Br J Pharmacol 2004;141:223-32.
- El Fortia, M., Badi, H., Elalem, Kh, Kadiki, O., and Topov, Y. Olibanum bezoar: complication of a traditional popular medicine. East Mediterr.Health J 2006;12(6):927-929.
- Meshkat S, Mahmoodi Baram S, Rajaei S, et al. Boswellia serrata extract shows cognitive benefits in a double-blind, randomized, placebo-controlled pilot clinical trial in individuals who suffered traumatic brain injury. Brain Inj 2022;36(4):553-559. PubMed
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
- Valente IVB, Garcia D, Abbott A, et al. The anti-proliferative effects of a frankincense extract in a window of opportunity phase ia clinical trial for patients with breast cancer. Breast Cancer Res Treat 2024;204(3):521-530. PubMed
Slippery Elm 3 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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