Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

SOD Booster (Superoxide Dismutase) Ingredients & Drug Interactions

by Life Extension

SOD Booster (Superoxide Dismutase) label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking SOD Booster (Superoxide Dismutase) against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

SOD Booster (Superoxide Dismutase) is a dietary supplement by Life Extension with 2 active ingredients. Its ingredients are commonly taken for antioxidant support, heart and blood vessel health, blood pressure support.Based on those ingredients, 811 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Aronia melanocarpa extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against SOD Booster (Superoxide Dismutase) by Life Extension

Ask about any prescription or over-the-counter medication and we check it for interactions with SOD Booster (Superoxide Dismutase) by Life Extension — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of SOD Booster (Superoxide Dismutase) by Life Extension

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

SOD Booster contains 2 active ingredients: Extramel melon pulp concentrate and aronia melanocarpa extract (chokeberry). The product also includes inactive ingredients — vegetable cellulose, maltodextrin, vegetable oil, silica, and microcrystalline cellulose — which act as capsule material and binders.

Chokeberry is a dark berry rich in polyphenols and antioxidants, traditionally used to support general wellness. Melon pulp concentrate is included for its nutrient profile, though we have no interaction data on file for it.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Chokeberry product and its label doesn't state a use — see Chokeberry's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for SOD Booster's effectiveness is limited. For cardiovascular disease, the data rates chokeberry as possibly ineffective — meaning existing research doesn't support a clear benefit.

For age-related cognitive decline, age-related macular degeneration, athletic performance, and cancer prevention, there isn't enough reliable evidence to rate how well it works. In other words, we don't have solid research backing these uses yet.

The evidence, ingredient by ingredient Chokeberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chokeberry is generally well tolerated when eaten as a food, but supplement safety at concentrated doses isn't well studied, so use caution with this product. The most common side effects are gastrointestinal — constipation, diarrhea, nausea, stomach cramps, and vomiting.

In small studies, around 14–53% of people drinking chokeberry juice daily reported these effects, depending on the dose and duration. We have no safety data on file for the melon pulp concentrate ingredient.

Because concentrated chokeberry supplements haven't been thoroughly studied, it's wise to talk with your doctor or pharmacist before starting, especially if you have a sensitive stomach or a history of GI issues.

Side effects, ingredient by ingredient Chokeberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Chokeberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 812 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product with your pharmacist or doctor if you take trabectedin (a cancer drug), blood thinners or antiplatelet drugs like warfarin, aspirin, or clopidogrel, diabetes medications like insulin or metformin, or any drug metabolized by the CYP3A4 enzyme — that's a broad group that includes many statins, blood pressure drugs, and immunosuppressants. Chokeberry may raise levels of CYP3A4 drugs or increase bleeding or low blood sugar risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

SOD Booster may be worth considering if you're looking for antioxidant support, but be cautious if you take blood thinners, diabetes medications, or especially trabectedin — the interaction risk is real. Stomach upset is common, so take it with food if your stomach is sensitive.

Before you start, run your medications through the checker on this page and talk it over with your doctor or pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about SOD Booster (Superoxide Dismutase), straight from the product label.

Brand Life Extension
Barcode (UPC) 737870236139
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2020
DSLD ID 232719
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for SOD Booster (Superoxide Dismutase) by Life Extension, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
UPC/BARCODE
737870236139
IngredientAmount% DV
Extramel Melon pulp concentrate10 mg--
Aronia melanocarpa extract300 mg--

Other ingredients: Vegetable Cellulose, Maltodextrin, Vegetable Oil, Silica, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Read the entire label and follow the directions carefully prior to use. Directions: Take one (1) capsule daily, or as recommended by a healthcare practitioner.

Precautions

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

Extramel is a registered trademark of Bionov.

Seals/Symbols

Non GMO LE Certified

Formulation

Non GMO LE Certified

Fights cellular oxidative stress

FDA Statement of Identity

Dietary Supplement

Storage

Store tightly closed in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

SOD Booster (Superoxide Dismutase) by Life Extension label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

SOD Booster (Superoxide Dismutase) label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in SOD Booster (Superoxide Dismutase) by Life Extension

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Extramel Melon pulp concentrate

10 mg per serving Form: Superoxide Dismutase

Aronia melanocarpa extract

Interacts with
811 drugs
300 mg per serving Form: Polyphenols

Chokeberry (aronia) is a dark berry rich in antioxidants called polyphenols, and it's widely eaten as juice, jam, and supplements. Early research hint...

Aronia melanocarpa extract monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Maltodextrin, Vegetable Oil, Silica, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

SOD Booster (Superoxide Dismutase) by Life Extension Drug Interactions

Want to check YOUR meds against SOD Booster (Superoxide Dismutase)?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
811Drugs
811 Moderate

Ingredients driving the most interactions

Aronia melanocarpa extract 811

Individual Drug Interactions

The ingredients in SOD Booster (Superoxide Dismutase) interact with 811 drugs. Click any drug to see the details.

1 of the 2 ingredients in SOD Booster (Superoxide Dismutase) interact with drugs. Each result below shows which ingredient is responsible. Aronia melanocarpa extract

Each ingredient & the kinds of drugs it affects

For each ingredient in SOD Booster (Superoxide Dismutase) with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Aronia melanocarpa extract4 drug types · 811 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Clinical and in vitro research suggests that chokeberry extract can temporarily inhibit platelet aggregation and decrease clot formation.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, chokeberry might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Some clinical research shows that chokeberry decreases levels of blood glucose in some patients with diabetes. However, other clinical research suggests that chokeberry has no significant effect on blood glucose levels.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that chokeberry inhibits CYP3A4. In humans, there is one case report of a drug interaction with trabectedin, a CYP3A4 substrate, which is hypothesized to have been caused by chokeberry inhibition of CYP3A4.

Likelihood Possible Evidence D
Trabectedin (Yondelis)

Theoretically, chokeberry might increase the effects and adverse effects of trabectedin.
In one case report, a patient drinking chokeberry juice developed rhabdomyolysis induced by trabectedin, a cytochrome P450 3A4 (CYP3A4) substrate. It is possible that inhibition of CYP3A4 by chokeberry juice might have inhibited the metabolism of trabectedin and increased trabectedin levels in this patient.

Likelihood Possible Evidence D
Aronia melanocarpa extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for SOD Booster (Superoxide Dismutase), from the product label.

Life Extension

See all Life Extension products
Name
Quality Supplements and Vitamins, Inc.
City
Ft. Lauderdale
State
FL
ZipCode
33309
Phone Number
1-866-280-2852
Web Address
LifeExtension.com
Pharmacist Counseling Corner

SOD Booster (Superoxide Dismutase) by Life Extension: Common Questions

Does SOD Booster (Superoxide Dismutase) by Life Extension interact with any medications?
Yes. Based on its ingredients, SOD Booster (Superoxide Dismutase) has a known interaction with 811 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
SOD Booster (Superoxide Dismutase) contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a blood thinner like warfarin?
Not without checking first. Chokeberry in this product may increase your bleeding risk when combined with blood thinners or antiplatelet drugs. Talk to your pharmacist or doctor before starting — they can tell you whether it's safe for you or if you need extra monitoring.
What are the most common side effects?
Stomach upset — constipation, diarrhea, nausea, stomach cramps, and vomiting. In small studies, 14–53% of people taking chokeberry had at least one of these, depending on how much they took and for how long. Taking it with food may help.
Does this actually work for heart health?
The research says chokeberry is possibly ineffective for cardiovascular disease, meaning current studies don't show a clear benefit. For other uses like memory, eye health, or athletic performance, there simply isn't enough reliable evidence yet.
Is it safe to take during pregnancy or while breastfeeding?
We don't have safety data on file for this supplement during pregnancy or lactation. Because concentrated chokeberry hasn't been studied in these situations, talk with your doctor or pharmacist before using it if you're pregnant or nursing.
What's melon pulp concentrate doing in here?
Extramel melon pulp concentrate is included for its nutrient profile, but we don't have interaction or effectiveness data for it on file. It's one of two active ingredients in this product.
Can I take this with my diabetes medications?
Check first. Some research suggests chokeberry lowers blood sugar, so taking it with insulin or other diabetes drugs might increase your risk of low blood sugar (hypoglycemia). Your doctor or pharmacist can review your specific medications and let you know if it's safe.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if SOD Booster (Superoxide Dismutase) is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

SOD Booster (Superoxide Dismutase) label
Go deeper

The Full Monographs Behind SOD Booster (Superoxide Dismutase)’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chokeberry

Interacts with 811 drugs

Chokeberry (aronia) is a dark berry rich in antioxidants called polyphenols, and it's widely eaten as juice, jam, and supplements. Early research hints it may support heart health, blood pre...

Read the full Chokeberry monograph →
Sources

Sources & How We Checked

SOD Booster (Superoxide Dismutase)'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chokeberry 8 references
  1. Sikora J, Broncel M, Markowicz M, Chalubinski M, Wojdan K, Mikiciuk-Olasik E. Short-term supplementation with Aronia melanocarpa extract improves platelet aggregation, clotting, and fibrinolysis in patients with metabolic syndrome. Eur J Nutr. 2012 Aug;51 PubMed
  2. Simeonov SB, Botushanov NP, Karahanian EB, Pavlova MB, Husianitis HK, Troev DM. Effects of Aronia melanocarpa juice as part of the dietary regimen in patients with diabetes mellitus. Folia Med (Plovdiv). 2002;44(3):20-3.
  3. Savikin K, Menkovic N, Zdunic G, Pljevljakusic D, Spasic S, Kardum N, Konic-Ristic A. Dietary supplementation with polyphenol-rich chokeberry juice improves skin morphology in cellulite. J Med Food. 2014 May;17(5):582-7. PubMed
  4. Bräunlich M, Christensen H, Johannesen S, Slimestad R, Wangensteen H, Malterud KE, Barsett H. In vitro inhibition of cytochrome P450 3A4 by Aronia melanocarpa constituents. Planta Med. 2013 Jan;79(2):137-41. PubMed
  5. Strippoli S, Lorusso V, Albano A, Guida M. Herbal-drug interaction induced rhabdomyolysis in a liposarcoma patient receiving trabectedin. BMC Complement Altern Med. 2013 Jul 30;13:199. PubMed
  6. Ryszawa N, Kawczynska-Drózdz A, Pryjma J, Czesnikiewicz-Guzik M, Adamek-Guzik T, Naruszewicz M, Korbut R, Guzik TJ. Effects of novel plant antioxidants on platelet superoxide production and aggregation in atherosclerosis. J Physiol Pharmacol. 2006 Dec;57(
  7. Milutinovic M, Velickovic Radovanovic R, Savikin K, et al. Chokeberry juice supplementation in type 2 diabetic patients - impact on health status. J Appl Biomed 2019;17(4):218-224. PubMed
  8. Lackner S, Sconocchia T, Ziegler T, et al. Immunomodulatory effects of aronia juice polyphenols-results of a randomized placebo-controlled human intervention study and cell culture experiments. Antioxidants (Basel) 2022;11(7):1283. PubMed

See these in context on the Chokeberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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