No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Sodium Fluoride Drops 0.5 mg Peach Flavored Ingredients & Drug Interactions

by H2 Pharma

Liquid Category: Mineral
No known interaction
The interaction bottom line No known interaction

Sodium Fluoride Drops 0.5 mg Peach Flavored is a dietary supplement by H2 Pharma with 1 active ingredient. Its ingredients are commonly taken for preventing tooth decay (cavities), strengthening tooth enamel, dental care for children in low-fluoride areas.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Sodium Fluoride Drops 0.5 mg Peach Flavored by H2 Pharma

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: fluoride at 0.5 mg per dose. Fluoride is a mineral that strengthens tooth enamel and helps prevent cavities.

The drops are flavored with peach and sweetened with sucralose; inactive ingredients include water, citric acid, sodium benzoate as a preservative, and food dyes.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: dental caries preventive in pediatric patients.
  • We looked for evidence on: Dental caries, tooth decay, cavity prevention, enamel strengthening.
  • The strongest evidence on file: Fluoride is rated "Effective" for Dental caries (Natural Medicines).

Fluoride is effective for preventing dental cavities (tooth decay). The evidence also suggests it may help with osteoporosis, dental plaque buildup, and gum inflammation (gingivitis), though the data for these uses is less established than for cavities.

The evidence, ingredient by ingredient Fluoride

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Fluoride at recommended dental doses is generally well tolerated. The main concern with oral fluoride is excess intake — too much, especially in children, can cause dental fluorosis (white spots or streaks on teeth) and other harm.

Most side effects reported are gastrointestinal symptoms. Rarely, people may have allergic reactions including rashes, lip swelling, or mouth sores.

Pregnancy and breastfeeding data are mixed: routine prenatal fluoride supplements are not recommended, though normal dietary and water fluoride intake is considered fine. If you're pregnant or nursing and wondering whether to use this product, talk with your doctor or pharmacist — they can advise you based on your fluoride intake from other sources.

Side effects, ingredient by ingredient Fluoride

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for this product in our data.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Sodium Fluoride Drops are a straightforward way to help prevent cavities, especially in children whose diet or water supply may not provide enough natural fluoride. The key is staying within recommended doses — excess fluoride can cause problems.

If you're pregnant, nursing, or have questions about whether this product fits your or your child's health picture, check with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 18, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sodium Fluoride Drops 0.5 mg Peach Flavored, straight from the product label.

Brand H2 Pharma
Barcode (UPC) 361269165504
Net contents 1.66 Fluid Ounce(s); 50 mL
Market status On market
Date entered into DSLD Dec 18, 2021
DSLD ID 264334
Product type Mineral
Supplement form Liquid
Dietary claims / uses Nutrient, All Other
Intended target group(s) Children 4 or More Years of Age, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sodium Fluoride Drops 0.5 mg Peach Flavored by H2 Pharma, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
50
UPC/BARCODE
361269165504
IngredientAmount% DV
Fluoride0.5 mg--

Other ingredients: Citric Acid, Methyl Paraben, Peach flavor, Water, Purified, D&C Red #33, Sodium Benzoate, Sodium Fluoride, Sucralose, Yellow #6

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

61269-165-50

Formulation

Sugar-free and saccharin-free

Suggested/Recommended/Usage/Directions

Shake well Dosage: See carton for dosage and administration information.

Formula

Description: Each 1 mL contains 0.5 mg fluoride ion (F-) from 1.1 mg sodium fluoride (NaF).

For use as a dental caries preventive in pediatric patients.

Precautions

Tamper evident: Do not use if seal under cap is torn, broken or missing.

Warning: Keep out of reach of children.

See for yourself

Sodium Fluoride Drops 0.5 mg Peach Flavored by H2 Pharma label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Sodium Fluoride Drops 0.5 mg Peach Flavored by H2 Pharma

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container50 Amounts shown are per serving.

Fluoride

No known
interactions
0.5 mg per serving

Fluoride is a mineral best known for preventing cavities and strengthening tooth enamel, and it is widely used in toothpaste, mouth rinses, and commun...

Fluoride monograph & interactions

Other (inactive) ingredients: Citric Acid, Methyl Paraben, Peach flavor, Water, Purified, D&C Red #33, Sodium Benzoate, Sodium Fluoride, Sucralose, Yellow #6. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sodium Fluoride Drops 0.5 mg Peach Flavored by H2 Pharma Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Sodium Fluoride Drops 0.5 mg Peach Flavored. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Sodium Fluoride Drops 0.5 mg Peach Flavored, from the product label.

H2 Pharma

See all H2 Pharma products
Name
H2-Pharma, LLC
City
Montgomery
State
AL
ZipCode
36117
Web Address
www.h2-pharma.com
Pharmacist Counseling Corner

Sodium Fluoride Drops 0.5 mg Peach Flavored by H2 Pharma: Common Questions

Does Sodium Fluoride Drops 0.5 mg Peach Flavored by H2 Pharma interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Sodium Fluoride Drops 0.5 mg Peach Flavored. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Sodium Fluoride Drops 0.5 mg Peach Flavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is fluoride safe for kids?
Fluoride at recommended doses is well tolerated and effective for preventing cavities in children. The important thing is to use the right dose for your child's age — excess fluoride, especially in young children, can cause dental fluorosis (white spots on teeth). Your pediatrician or dentist can recommend the right amount based on your child's age and your local water fluoride level.
What are the most common side effects?
Stomach upset is the most common side effect reported with oral fluoride. Allergic reactions are rare but can include rashes, lip swelling, mouth sores, or breathing trouble — if any of these happen, stop use and talk to your doctor right away.
Can I use this if I'm pregnant?
The safety data are mixed. Routine prenatal fluoride supplements are not recommended, though normal dietary intake and fluoridated water are considered fine. Because every pregnancy is unique, talk with your doctor or pharmacist about your fluoride intake from all sources before adding a supplement.
Does fluoride really prevent cavities?
Yes — fluoride is effective for preventing dental cavities. It strengthens tooth enamel and makes teeth more resistant to decay, which is why it's so common in toothpaste and drinking water.
Can fluoride help with osteoporosis or gum disease?
The evidence suggests fluoride may help with osteoporosis and gum inflammation, but the data is less established than for cavities. If you're interested in fluoride for either of those reasons, talk with your doctor about whether it's right for your situation.
What's in this besides fluoride?
The drops contain water, peach flavoring, sucralose for sweetness, citric acid, sodium benzoate as a preservative, and food dyes. There are no active ingredients other than fluoride.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sodium Fluoride Drops 0.5 mg Peach Flavored is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sodium Fluoride Drops 0.5 mg Peach Flavored label
Go deeper

The Full Monographs Behind Sodium Fluoride Drops 0.5 mg Peach Flavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Sodium Fluoride Drops 0.5 mg Peach Flavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 39 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fluoride 39 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. Washington, DC: National Academy Press, 1999. Available at: http://books.nap.edu/books/0309063507/html/index.html.
  3. Position of the American Dietetic Association: the impact of fluoride on health. J Am Diet Assoc 2001;101:126-32.. PubMed
  4. Brown JP, Josse RG, et al. 2002 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada. CMAJ 2002;167:S1-S34..
  5. Haguenauer D, Welch V, Shea B, et al. Fluoride for treating postmenopausal osteoporosis.(Cochrane Review). Cochrane Database Syst Rev 2002;(4):CD002825.. PubMed
  6. Choi AL, Sun G, Zhang Y, Grandjean P. Developmental fluoride neurotoxicity: a systematic review and meta-analysis. Environ Health Perspect. 2012 Oct;120(10):1362-8. PubMed
  7. Enamandram M, Das S, Chaney KS. Cheilitis and urticaria associated with stannous fluoride in toothpaste. J Am Acad Dermatol. 2014 Sep;71(3):e75-6. PubMed
  8. Foti C, Romita P, Ficco D, Bonamonte D, Angelini G. Allergic contact cheilitis to amine fluoride in a toothpaste. Dermatitis. 2014 Jul-Aug;25(4):209. PubMed
  9. Grey A, Garg S, Dray M, Purvis L, Horne A, Callon K, Gamble G, Bolland M, Reid IR, Cundy T. Low-dose fluoride in postmenopausal women: a randomized controlled trial. J Clin Endocrinol Metab. 2013 Jun;98(6):2301-7. PubMed
  10. Peters P, Drummond C. Perioral dermatitis from high fluoride dentifrice: a case report and review of literature. Aust Dent J. 2013 Sep;58(3):371-2. PubMed
  11. Sälzer S, Slot DE, Dörfer CE, Van der Weijden GA. Comparison of triclosan and stannous fluoride dentifrices on parameters of gingival inflammation and plaque scores: a systematic review and meta-analysis. Int J Dent Hyg. 2015 Feb;13(1):1-17.
  12. Till C, Green R, Flora D, et al. Fluoride exposure from infant formula and child IQ in a Canadian birth cohort. Environ Int. 2020;134:105315. PubMed
  13. Seddek AL, Ghallab A. Fluoride: No evidence of developmental neurotoxicity due to current exposure levels in Europe. Arch Toxicol. 2020;94(7):2543-2544. PubMed
  14. Green R, Lanphear B, Hornung R, et al. Association between maternal fluoride exposure during pregnancy and IQ scores in offspring in Canada. JAMA Pediatr. 2019;173(10):940-8. PubMed
  15. Guth S, Hüser S, Roth A, et al. Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses. Arch Toxicol. 2020;94(5):1375-1415. PubMed
  16. Canadian Dental Association. CDA position on use of fluorides in caries prevention. March 2012. Available at: https://www.cda-adc.ca/_files/position_statements/fluoride.pdf. Accessed December 9, 2020.
  17. Bellinger DC. Is fluoride potentially neurotoxic? JAMA Pediatr. 2019. PubMed
  18. Till C, Green R, Lanphear B. Association between maternal fluoride exposure and child IQ-reply. JAMA Pediatr. 2020;174(2):216-217. PubMed
  19. Bledsoe J, Breiger D, McKeever J. Association between maternal fluoride exposure and child IQ. JAMA Pediatr. 2020;174(2):213. PubMed
  20. Gong CX, James NE. Association between maternal fluoride exposure and child IQ. JAMA Pediatr. 2020;174(2):212-213. PubMed
  21. Bashash M, Marchand M, Hu H, et al. Prenatal fluoride exposure and attention deficit hyperactivity disorder (ADHD) symptoms in children at 6-12?years of age in Mexico City. Environ Int. 2018;121(Pt 1):658-666. PubMed
  22. Riddell JK, Malin AJ, Flora D, McCague H, Till C. Association of water fluoride and urinary fluoride concentrations with attention deficit hyperactivity disorder in Canadian youth. Environ Int. 2019;133(Pt B):105190. PubMed
  23. Wei Y, Zhu J, Wetzstein SA. Plasma and water fluoride levels and hyperuricemia among adolescents: A cross-sectional study of a nationally representative sample of the United States for 2013-2016. Ecotoxicol Environ Saf 2021;208:111670. PubMed
  24. Davoudi M, Barjasteh-Askari F, Sarmadi M, et al. Relationship of fluoride in drinking water with blood pressure and essential hypertension prevalence: a systematic review and meta-analysis. Int Arch Occup Environ Health 2021;94(6):1137-1146. PubMed
  25. Veneri F, Vinceti M, Generali L, et al. Fluoride exposure and cognitive neurodevelopment: Systematic review and dose-response meta-analysis. Environ Res 2023;221:115239. PubMed
  26. Iamandii I, De Pasquale L, Giannone ME, et al. Does fluoride exposure affect thyroid function? A systematic review and dose-response meta-analysis. Environ Res 2024;242:117759. PubMed
  27. Mou Y, Qu T, Wang R, Zhang Y, He Z, Gu S. The association of high-fluoride and high-iodine combined exposure with dental fluorosis and goiter: a meta-analysis. Environ Geochem Health 2023;45(6):3143-3153. PubMed
  28. Hall M, Lanphear B, Chevrier J, Hornung R, Green R, Goodman C, et al. Fluoride exposure and hypothyroidism in a Canadian pregnancy cohort. Sci Total Environ 2023;869:161149. PubMed
  29. Malin AJ, Riddell J, McCague H, Till C. Fluoride exposure and thyroid function among adults living in Canada: Effect modification by iodine status. Environ Int 2018;121(Pt 1):667-674. PubMed
  30. Do LG, Sawyer A, John Spencer A, et al. Early Childhood Exposures to Fluorides and Cognitive Neurodevelopment: A Population-Based Longitudinal Study. J Dent Res 2024; Dec. PubMed
  31. Do LG, Spencer AJ, Sawyer A, et al. Early Childhood Exposures to Fluorides and Child Behavioral Development and Executive Function: A Population-Based Longitudinal Study. J Dent Res 2023;102(1):28-36. PubMed
  32. Farmus L, Till C, Green R, et al. Critical windows of fluoride neurotoxicity in Canadian children. Environ Res 2021;200:111315. PubMed
  33. Grandjean P, Meddis A, Nielsen F, et al. Dose dependence of prenatal fluoride exposure associations with cognitive performance at school age in three prospective studies. Eur J Public Health 2024;34(1):143-149. PubMed
  34. Griebel-Thompson AK, Sands S, Chollet-Hinton L, et al. A Scoping Review of Iodine and Fluoride in Pregnancy in Relation to Maternal Thyroid Function and Offspring Neurodevelopment. Adv Nutr 2023;14(2):317-338. PubMed
  35. Kumar JV, Moss ME, Liu H, Fisher-Owens S. Association between low fluoride exposure and children's intelligence: a meta-analysis relevant to community water fluoridation. Public Health 2023;219:73-84. PubMed
  36. Levy SM. Caution Needed in Interpreting the Evidence Base on Fluoride and IQ. JAMA Pediatr 2025. PubMed
  37. Taylor KW, Eftim SE, Sibrizzi CA, et al. Fluoride Exposure and Children's IQ Scores: A Systematic Review and Meta-Analysis. JAMA Pediatr 2025. PubMed
  38. Goodman CV, Hall M, Green R, et al. Iodine Status Modifies the Association between Fluoride Exposure in Pregnancy and Preschool Boys' Intelligence. Nutrients 2022;14(14):2920. PubMed
  39. Castiblanco-Rubio GA, Muñoz-Rocha TV, Téllez-Rojo MM, et al. Dietary Influences on Urinary Fluoride over the Course of Pregnancy and at One-Year Postpartum. Biol Trace Elem Res 2022;200(4):1568-1579. PubMed

See these in context on the Fluoride monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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