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Dietary supplement

Stinging Nettle Ingredients & Drug Interactions

by Mountain Meadow Herbs

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Stinging Nettle is a dietary supplement by Mountain Meadow Herbs with 1 active ingredient. Its ingredients are commonly taken for enlarged prostate (bph) symptoms, seasonal allergies, joint pain and arthritis.Based on those ingredients, 164 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Stinging Nettle Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Stinging Nettle by Mountain Meadow Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

The active ingredient is stinging nettle leaf extract, made from the leaves of the stinging nettle plant. It is the only active ingredient listed in this liquid.

The inactive ingredients are glycerin and distilled water.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Stinging Nettle's overall clinical evidence instead.

Moderate

Some clinical evidence supports Stinging Nettle for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Diabetes — rated "Possibly Effective" (Natural Medicines).

The only rating in our data that reaches a usable level is for diabetes, which is rated Possibly Effective. For allergic rhinitis (hay fever), anemia, asthma, benign prostatic hyperplasia (BPH, an enlarged prostate), and gingivitis (gum inflammation), the rating is Insufficient Reliable Evidence To Rate, so the evidence for those uses isn't established in the data we hold.

The evidence, ingredient by ingredient Stinging Nettle

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Stinging nettle is generally well tolerated for most adults when used as directed, though evidence and product quality vary. The most common side effects taken orally are constipation and diarrhea.

Applied to skin, contact with the raw plant can cause itching, rash, and stinging. A case report describes liver injury in a woman who had taken an herbal liver detox tea containing stinging nettle and other ingredients.

In pregnancy, the safety data is rated Likely Unsafe, and traditional concerns about effects on the uterus mean it is best avoided. Breastfeeding safety has not been established, so talk with your doctor before using it while nursing.

Side effects, ingredient by ingredient Stinging Nettle

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Stinging Nettle.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 164 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check antidiabetes drugs, diuretics (water pills), lithium, and warfarin (Coumadin) before taking this product. Every interaction in our data is rated Moderate, and none is rated Major.

Stinging nettle may affect blood sugar, fluid balance, lithium levels, and warfarin's effects, so ask your own doctor or pharmacist to review your full medication list first.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product may interest adults who are considering stinging nettle, though its strongest rating is only Possibly Effective, for diabetes. Anyone taking antidiabetes drugs, diuretics, lithium, or warfarin should be especially careful and talk it over with their own doctor or pharmacist first.

If you are pregnant or breastfeeding, the safety data advises against use in pregnancy, so talk with your own healthcare provider before considering it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Stinging Nettle, straight from the product label.

Brand Mountain Meadow Herbs
Barcode (UPC) 813086015208
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD May 23, 2024
DSLD ID 310162
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Children (All), Pregnant Women, Infants/Baby (0 - 1 Year)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Stinging Nettle by Mountain Meadow Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 Teaspoon(s)
Maximum serving Sizes:
0.25 Teaspoon(s)
Servings per container
96
UPC/BARCODE
813086015208
IngredientAmount% DV
Stinging Nettle Leaf Extract1.25 mL--

Other ingredients: Glycerin, Water, Distilled

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Leaf Urtica dioica

Formulation

Alcohol free GF (Gluten free)

Hand-made extract

Vegan

Whole-body health benefits Soothing support for joints & muscles High in naturally occurring calcium Support prostate health

FDA Statement of Identity

Herbal Dietary Supplement

Seals/Symbols

Made in Montana USA

Suggested/Recommended/Usage/Directions

Suggested Use: 5 drops - 1/4 tsp. Take 1-3 times daily, or as needed. See catalog for dosage information. Shake well.

Precautions

Caution: If you are pregnant, nursing, have a medical condition, or are taking a prescription, consult your health care provider before using this product.

Keep out of reach of children.

Storage

Store in a cool, dry place out of sunlight.

General Statements

The MMH Three-Leaf Promise: Our high-standards produce nothing less than Pure, Safe, and Effective herbal products. You will always feel that We Care - through our products, our service, and our understanding. We deliver on time.

1 dropperful = approx. 1/8 tsp.

See for yourself

Stinging Nettle by Mountain Meadow Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Stinging Nettle by Mountain Meadow Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 Teaspoon(s) Dosage formLiquid Servings per container96 Amounts shown are per serving.

Stinging Nettle Leaf Extract

Interacts with
164 drugs
1.25 mL per serving Form: Glycerin, Water, Distilled

Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence...

Stinging Nettle Leaf Extract monograph & interactions

Other (inactive) ingredients: Glycerin, Water, Distilled. These complete the product’s ingredient list but are not active constituents.

Interaction report

Stinging Nettle by Mountain Meadow Herbs Drug Interactions

Want to check YOUR meds against Stinging Nettle?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

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164Drugs
164 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Stinging Nettle with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Stinging Nettle Leaf Extract4 drug types · 164 drugs

Antidiabetes Drugs

Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.

Likelihood Possible Evidence B
Diuretic Drugs

Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.

Likelihood Possible Evidence D
Lithium

Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Stinging Nettle, from the product label.

Mountain Meadow Herbs

See all Mountain Meadow Herbs products
Name
Mountain Meadow Herbs, Inc.
Street Address
1019 Hard Rock Rd
City
Somers
State
MT
ZipCode
59932
Phone Number
888.528.8615
Web Address
www.mmherbs.com
Pharmacist Counseling Corner

Stinging Nettle by Mountain Meadow Herbs: Common Questions

Does Stinging Nettle by Mountain Meadow Herbs interact with any medications?
Yes. Based on its ingredients, Stinging Nettle has a known interaction with 164 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Stinging Nettle contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is stinging nettle safe to take during pregnancy?
The safety data rates stinging nettle as Likely Unsafe in pregnancy, and traditional concerns about the uterus mean it is best avoided. Talk with your own doctor or pharmacist before considering it.
What are the most common side effects of stinging nettle?
When taken orally, the most common side effects are constipation and diarrhea. Skin contact with the raw plant can cause itching, rash, and stinging.
Does stinging nettle work for hay fever?
Hay fever (allergic rhinitis) is rated Insufficient Reliable Evidence To Rate, so the evidence for that use isn't established in the data we hold.
What is stinging nettle used for?
The product's leaf extract is linked to diabetes, which is rated Possibly Effective. Other uses, including asthma, anemia, BPH, and gingivitis, are rated Insufficient Reliable Evidence To Rate.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Stinging Nettle is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Stinging Nettle label
Sources

Sources & How We Checked

Stinging Nettle's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stinging Nettle 23 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  5. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  6. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  7. Mittman P. Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis. Planta Med 1990;56:44-7.
  8. Vontobel HP, Herzog R, Rutishauser G, Kres H. [Results of a double-blind study on the effectiveness of ERU (extractum radicis Urticae) capsules in conservative treatment of benign prostatic hyperplasia]. (Abstract). Urologe A 1985;24:49-51.
  9. Randall C, Randall H, Dobbs F, et al. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain. J R Soc Med 2000;93:305-9. PubMed
  10. Caliskaner Z, Karaayvaz M, Ozturk S. Misuse of a herb: stinging nettle (Urtica urens) induced severe tongue oedema. Complement Ther Med 2004;12:57-8. PubMed
  11. Krzeski, T., Kazon, M., Borkowski, A., Witeska, A., and Kuczera, J. Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses. Clin Ther 1993;15(6):1011-1020.
  12. Randall, C., Meethan, K., Randall, H., and Dobbs, F. Nettle sting of Urtica dioica for joint pain--an exploratory study of this complementary therapy. Complement Ther Med 1999;7(3):126-131. PubMed
  13. Tahri, A., Yamani, S., Legssyer, A., Aziz, M., Mekhfi, H., Bnouham, M., and Ziyyat, A. Acute diuretic, natriuretic and hypotensive effects of a continuous perfusion of aqueous extract of Urtica dioica in the rat. J Ethnopharmacol 2000;73(1-2):95-100. PubMed
  14. Sahin, M., Yilmaz, H., Gursoy, A., Demirel, A. N., Tutuncu, N. B., and Guvener, N. D. Gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (Urtica dioica). N.Z.Med.J. 2007;120(1265):U2803.
  15. Randall, C., Dickens, A., White, A., Sanders, H., Fox, M., and Campbell, J. Nettle sting for chronic knee pain: a randomised controlled pilot study. Complement Ther.Med. 2008;16(2):66-72. PubMed
  16. Rayburn, K., Fleischbein, E., Song, J., Allen, B., Kundert, M., Leiter, C., and Bush, T. Stinging nettle cream for osteoarthritis. Altern.Ther.Health Med. 2009;15(4):60-61.
  17. Oliver, F., Amon, E. U., Breathnach, A., Francis, D. M., Sarathchandra, P., Black, A. K., and Greaves, M. W. Contact urticaria due to the common stinging nettle (Urtica dioica)-- histological, ultrastructural and pharmacological studies. Clin Exp Dermato PubMed
  18. Kulze, A. and Greaves, M. Contact urticaria caused by stinging nettles. Br.J Dermatol. 1988;119(2):269-270. PubMed
  19. Patten G. Medicinal plant review: Urtica. Aust J Med Herbalism 1993;5(1):5-13.
  20. Maor D, Little M. Skin contact with a stinging tree requiring intensive care unit admission. Contact Dermatitis. 2017 Nov;77(5):335-37. PubMed
  21. Easton L, Vaid S, Nagel AK, Venci JV, Fortuna RJ. Stinging Nettle (Urtica dioica): An Unusual Case of Galactorrhea. Am J Case Rep 2021;22:e933999. PubMed
  22. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed
  23. Nnamani I, Tolu-Akinnawo O, Dufera RR, Akintunde A, Maliakkal B. Tinospora cordifolia (Guduchi/Giloy)-Induced Liver Injury: A Case Review. Cureus 2023;15(5):e39793. PubMed

See these in context on the Stinging Nettle monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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