Interactions on record — worth a quick check against your medications. Based on 6 of 8 ingredients. Check your meds →
Dietary supplement

Sturdy Organic Bone Supplement Ingredients & Drug Interactions

by Khroma Herbal Products

Sturdy Organic Bone Supplement label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sturdy Organic Bone Supplement against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Sturdy Organic Bone Supplement is a dietary supplement by Khroma Herbal Products with 8 active ingredients. Its ingredients are commonly taken for cough and sore throat, dry mouth and throat irritation, digestive upset and heartburn.Based on those ingredients, 2,108 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Marshmallow, organic Comfrey, organic Scullcap. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Sturdy Organic Bone Supplement by Khroma Herbal Products

Ask about any prescription or over-the-counter medication and we check it for interactions with Sturdy Organic Bone Supplement by Khroma Herbal Products — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Sturdy Organic Bone Supplement by Khroma Herbal Products

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 8 active ingredients.

This liquid supplement contains 8 active plant ingredients: organic Plantain, organic Marshmallow, organic Mullein, organic Gravel, organic Comfrey, organic Lungwort, organic Black Walnut, and organic Scullcap. The inactive ingredients are organic Vegetable Glycerin and Water.

We don't have effectiveness data in our files for most of these ingredients toward bone health. The product's name suggests it's meant to support bone strength, but the evidence we hold doesn't establish whether these specific plants work for that purpose.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence supporting these ingredients for bone health isn't established in the data we hold. For several of them — Marshmallow, Mullein, Comfrey, Lungwort, Black Walnut, and Scullcap — our records show insufficient reliable evidence to rate their use for any condition.

Without established effectiveness data, we can't speak to whether this formula does what the name suggests.

The evidence, ingredient by ingredient Marshmallow Mullein Comfrey Lungwort Black Walnut Skullcap

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Comfrey is the major safety red flag here. Oral use of comfrey is unsafe due to liver toxicity — it can cause ascites (fluid buildup), cirrhosis, hepatic fibrosis, and in severe cases, liver failure.

This damage can appear as late as 2 years after use ends. Comfrey can also damage the lungs, raising blood pressure in those vessels.

Marshmallow and Mullein are generally well tolerated for short-term use, but human safety data are limited. Black Walnut's leaf, bark, or hull may cause stomach upset due to tannin content, and both the nut and other parts can trigger allergic reactions in sensitive people — tree nuts are a major food allergen.

Scullcap may cause sedation, cognitive impairment, digestive upset, and vivid dreams at higher doses. None of these ingredients have adequate safety data for pregnancy or breastfeeding — all are best avoided in those situations.

Side effects, ingredient by ingredient Marshmallow Mullein Comfrey Lungwort Black Walnut Skullcap

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 6 matched ingredients can interact with medications — Comfrey, Mullein, Marshmallow, Skullcap.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; lithium.
  • For scale: 2,109 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this supplement, check with your pharmacist if you take any of these: hepatotoxic drugs or any medication that stresses your liver (Moderate severity, due to Comfrey); lithium or other mood stabilizers (Moderate severity, due to Marshmallow); blood thinners or antiplatelet drugs like warfarin or aspirin (Minor severity, due to Mullein); or CNS depressants such as benzodiazepines, sedatives, or opioid painkillers (Minor severity, due to Scullcap). We could not check Plantain or Gravel against any medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product carries real risks, especially from Comfrey, which shouldn't be taken by mouth. If you take lithium, other medications that affect your liver, blood thinners, or sedating drugs, check with your pharmacist before using it.

Pregnancy and breastfeeding are not appropriate times for this supplement. Talk with your pharmacist or doctor about whether this product is right for your needs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sturdy Organic Bone Supplement, straight from the product label.

Brand Khroma Herbal Products
Barcode (UPC) 642310999867
Net contents 2 Oz(s)
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 231359
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sturdy Organic Bone Supplement by Khroma Herbal Products, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Dropper(s)
Maximum serving Sizes:
3 Dropper(s)
Servings per container
30
UPC/BARCODE
642310999867
IngredientAmount% DV
organic Plantain0 NP--
organic Marshmallow0 NP--
organic Mullein0 NP--
organic Gravel0 NP--
organic Comfrey0 NP--
organic Lungwort0 NP--
organic Black Walnut0 NP--
organic Scullcap0 NP--

Other ingredients: organic Vegetable Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Shake well before each use. Take 3 droppers full (or 20-30 drops) 1-2 times daily or as needed. Liquid herbal tinctures may be administered directly into the mouth or may be put into water, tea, or juice, if preferred.

Take 3 droppers full once daily

Storage

For longest shelf life, refrigerate after opening

Formulation

Vegan friendly

Maximum strength

Contains no gluten, corn, animal products, alcohol, pesticides, artificial ingredients or preservatives.

Organic, small batched, hand crafted, family run business

Strong bones Healthy cartilage Smooth joints

Alcohol free tincture

General Statements

Satisfaction guaranteed

We are passionate about healthy living and only use the highest quality, ethically sourced ingredients

FDA Disclaimer Statement

These statements have not been evaluated by the FDA.

FDA Statement of Identity

Dietary Supplement

Precautions

Please consult your physician before taking this or any dietary supplement.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sturdy Organic Bone Supplement by Khroma Herbal Products label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sturdy Organic Bone Supplement label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sturdy Organic Bone Supplement by Khroma Herbal Products

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Dropper(s) Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Organic Plantain

0 NP per serving

Organic Marshmallow

Interacts with
2,040 drugs
0 NP per serving

Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats,...

Organic Marshmallow monograph & interactions

Organic Mullein

Interacts with
122 drugs
0 NP per serving

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality huma...

Organic Mullein monograph & interactions

Organic Gravel

0 NP per serving

Organic Comfrey

Interacts with
438 drugs
0 NP per serving

Comfrey is a traditional herb used mainly on the skin for bruises, sprains, and joint pain, and some topical products show modest benefit for these us...

Organic Comfrey monograph & interactions

Organic Lungwort

No known
interactions
0 NP per serving

Lungwort (Pulmonaria officinalis) is a traditional European herb long used as a tea for coughs and minor breathing complaints, named for its lung-shap...

Organic Lungwort monograph & interactions

Organic Black Walnut

No known
interactions
0 NP per serving

Black walnut is a tree whose green hulls are traditionally used as a natural antiparasitic and digestive remedy, but solid human evidence for these us...

Organic Black Walnut monograph & interactions

Organic Scullcap

Interacts with
248 drugs
0 NP per serving

American skullcap is an herb traditionally used to calm anxiety and promote relaxation, but solid human evidence is very limited. It is generally cons...

Organic Scullcap monograph & interactions

Other (inactive) ingredients: Organic Vegetable Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sturdy Organic Bone Supplement by Khroma Herbal Products Drug Interactions

Want to check YOUR meds against Sturdy Organic Bone Supplement?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,108Drugs
613 Moderate 1,495 Minor

Ingredients driving the most interactions

organic Marshmallow 2,040
organic Comfrey 438
organic Scullcap 248
organic Mullein 122

Individual Drug Interactions

The ingredients in Sturdy Organic Bone Supplement interact with 2,108 drugs. Click any drug to see the details.

4 of the 8 ingredients in Sturdy Organic Bone Supplement interact with drugs. Each result below shows which ingredient is responsible. organic Marshmallow organic Comfrey organic Scullcap organic Mullein

Each ingredient & the kinds of drugs it affects

For each ingredient in Sturdy Organic Bone Supplement with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Marshmallow3 drug types · 2,040 drugs

Lithium

Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.

Likelihood Possible Evidence D
organic Marshmallow full monograph & interactions

organic Comfrey2 drug types · 438 drugs

Cytochrome P450 3A4 (Cyp3A4) Inducers

Theoretically, CYP3A4 inducers might increase the risk of adverse effects from the pyrrolizidine alkaloid constituents in comfrey.
CYP3A4 enzymes convert pyrrolizidine alkaloids, constituents of comfrey, to toxic metabolites. Some case reports show that enzyme inducers, such as phenobarbital, seem to enhance the toxicity of comfrey.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, comfrey might have additive adverse effects on the liver when used with hepatotoxic drugs.
Due to its pyrrolizidine alkaloid constituents, comfrey can cause hepatotoxic effects, including ascites, cirrhosis, hepatic fibrosis, hepatomegaly, and sinusoidal obstruction syndrome.

Likelihood Possible Evidence D
organic Comfrey full monograph & interactions

organic Scullcap1 drug type · 248 drugs

Cns Depressants

Theoretically, skullcap can have additive effects when used with other CNS depressants.
Animal and clinical research suggests that skullcap can cause sedation and cognitive impairment.

Likelihood Possible Evidence D
organic Scullcap full monograph & interactions

organic Mullein1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot. This is likely due to at least one of the known constituents of muellein, triterpenoid saponins. However, the effects appear to be mild and results have been inconsistent. Extracts from different plant parts have been show to have varying anticoagulant strengths, with water-based ones being more potent than alcohol-based extracts.

Likelihood Unlikely Evidence A
organic Mullein full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sturdy Organic Bone Supplement, from the product label.

Khroma Herbal Products

See all Khroma Herbal Products products
Name
Khroma Herbal Products
Web Address
www.khromaherbs.com
Pharmacist Counseling Corner

Sturdy Organic Bone Supplement by Khroma Herbal Products: Common Questions

Does Sturdy Organic Bone Supplement by Khroma Herbal Products interact with any medications?
Yes. Based on its ingredients, Sturdy Organic Bone Supplement has a known interaction with 2,108 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sturdy Organic Bone Supplement contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take this while I'm pregnant?
No. Comfrey is rated likely unsafe in pregnancy due to liver toxicity and possible harm to the baby. The other ingredients also lack enough safety data — all are best avoided during pregnancy. Please talk with your doctor or pharmacist before considering any supplement in pregnancy.
What is Comfrey, and why is it a concern?
Comfrey is a plant that contains compounds called pyrrolizidine alkaloids, which can damage your liver when taken by mouth. This damage can lead to serious conditions like cirrhosis, liver fibrosis, and even liver failure — sometimes months or years after you stop using it. Oral use of comfrey is considered unsafe.
Can I take this if I use a sleep aid or anxiety medication?
Not without checking first. Scullcap in this formula can add to the sedating and cognitive effects of CNS depressants like benzodiazepines and sleep aids. Ask your pharmacist whether it's safe to combine them.
What does Black Walnut do in this supplement?
We don't have established evidence that Black Walnut works for bone health or any other condition. The ingredient is generally well tolerated in short-term use, though the leaf, bark, and hull contain tannins that may cause stomach upset, and tree nuts can trigger allergic reactions in sensitive people.
Will Marshmallow affect how my other medications work?
Yes, possibly. The mucilage in Marshmallow can interfere with how your body absorbs other oral drugs. To avoid this, take Marshmallow at least 30 to 60 minutes after any other oral medication. If you take lithium, Marshmallow may also raise its levels in your blood, risking toxicity.
Are there any side effects I should expect from this supplement?
Most common would be digestive upset (from Black Walnut's tannins or Scullcap), sedation or fuzzy thinking (from Scullcap), and skin irritation if applied topically. Data on side effects are limited for most of these ingredients, and safety hasn't been well studied in humans over the long term.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sturdy Organic Bone Supplement is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sturdy Organic Bone Supplement label
Go deeper

The Full Monographs Behind Sturdy Organic Bone Supplement’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Marshmallow

Interacts with 2,040 drugs

Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...

Read the full Marshmallow monograph → Herb & supplement monograph

Mullein

Interacts with 122 drugs

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality human studies are lacking, so its benefits a...

Read the full Mullein monograph → Herb & supplement monograph

Comfrey

Interacts with 438 drugs

Comfrey is a traditional herb used mainly on the skin for bruises, sprains, and joint pain, and some topical products show modest benefit for these uses. However, comfrey contains compounds...

Read the full Comfrey monograph → Herb & supplement monograph

Lungwort

Lungwort (Pulmonaria officinalis) is a traditional European herb long used as a tea for coughs and minor breathing complaints, named for its lung-shaped, spotted leaves. There is very little...

Read the full Lungwort monograph → Herb & supplement monograph

Black Walnut

Black walnut is a tree whose green hulls are traditionally used as a natural antiparasitic and digestive remedy, but solid human evidence for these uses is lacking. It contains a compound ca...

Read the full Black Walnut monograph → Herb & supplement monograph

Skullcap

Interacts with 248 drugs

American skullcap is an herb traditionally used to calm anxiety and promote relaxation, but solid human evidence is very limited. It is generally considered relatively safe for short-term us...

Read the full Skullcap monograph →
Sources

Sources & How We Checked

Sturdy Organic Bone Supplement's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 27 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Marshmallow 5 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Hage-Sleiman R, Mroueh M, Daher CF. Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon. Pharm Biol 2011;49(3):327-33.

See these in context on the Marshmallow monograph →

Mullein 2 references
  1. Castro AI, Carmona JB, Gonzales FG, Nestar OB. Occupational airborne dermatitis from gordolobo (Verbascum densiflorum). Contact Dermatitis 2006;55(5):301.
  2. Flores Echaiz C, Al Ali A, Cao AQ, Sasseville D. Simultaneous contact dermatitis caused by Asteraceae and Verbascum thapsus. Contact Dermatitis 2017;76(5):316-8.

See these in context on the Mullein monograph →

Comfrey 13 references
  1. Stewart MJ, Steenkamp V. Pyrrolizidine poisoning: a neglected area in human toxicology. Ther Drug Monit 2001;23:698-708. PubMed
  2. Food and Drug Administration. FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. July 6, 2001. Available at: http://www.cfsan.fda.gov/~dms/dspltr06.html.
  3. Stickel F, Seitz HK. The efficacy and safety of comfrey. Public Health Nutr 2000;3:501-8. PubMed
  4. Chojkier M. Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids. J Hepatol 2003;39:437-46. PubMed
  5. Wang YP, Yan J, Fu PP, Chou MW. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. Toxicol Lett 2005;155:411-20. PubMed
  6. Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., and Staiger, C. Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study. Phytome
  7. Gyorik, S. and Stricker, H. Severe pulmonary hypertension possibly due to pyrrolizidine alkaloids in polyphytotherapy. Swiss.Med.Wkly. 4-4-2009;139(13-14):210-211.
  8. Giannetti, B. M., Staiger, C., Bulitta, M., and Predel, H. G. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo controlled, multicentre trial. Br.J Spor PubMed
  9. Tanret, I. and Duh, D. [Pharmaceutical sheet. Symphytum officinale L., dermal use (Flexagile cream)]. J Pharm.Belg. 2012;(1):41-42.
  10. Laslett, L. L., Quinn, S. J., Darian-Smith, E., Kwok, M., Fedorova, T., Korner, H., Steels, E., March, L., and Jones, G. Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised contr
  11. Frost R, Macpherson H, O'meara S. A critical scoping review of external uses of comfrey (Symphytum spp.). Complement Ther Med. 2013;21(6):724-45. PubMed
  12. Pabst H, Schaefer A, Staiger C, Junker-samek M, Predel HG. Combination of comfrey root extract plus methyl nicotinate in patients with conditions of acute upper or low back pain: a multicentre randomised controlled trial. Phytother Res. 2013;27(6):811-7. PubMed
  13. Smith DB, Jacobson BH. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. J Chiropr Med. 2011;10(3) PubMed

See these in context on the Comfrey monograph →

Lungwort 1 reference
  1. Pyrrolizidine Alkaloids — NIH LiverTox Source

See these in context on the Lungwort monograph →

Black Walnut 3 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor

See these in context on the Black Walnut monograph →

Skullcap 3 references
  1. Wolfson P, Hoffmann DL. An investigation into the efficacy of Scutellaria lateriflora in healthy volunteers. Altern Ther Health Med 2003;9:74-8.
  2. Awad, R., Arnason, J. T., Trudeau, V., Bergeron, C., Budzinski, J. W., Foster, B. C., and Merali, Z. Phytochemical and biological analysis of skullcap (Scutellaria lateriflora L.): a medicinal plant with anxiolytic properties. Phytomedicine. 2003;10(8):6 PubMed
  3. Brock C, Whitehouse J, Tewfik I, Towell T. American skullcap (Scutellaria lateriflora): a randomised, double-blind placebo-controlled crossover study of its effects on mood in healthy volunteers. Phytother Res 2014;28(5):692-8.

See these in context on the Skullcap monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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