Sulbutiamine Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Sulbutiamine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Sulbutiamine is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, memory and focus, mental clarity.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Sulbutiamine by BulkSupplements.com
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product is a single active ingredient: sulbutiamine, a form of thiamine (vitamin B1). Sulbutiamine is a synthetic derivative designed to mimic how your body uses B1 for energy and nerve function.
There are no inactive fillers — just the powder itself.
Does it work?
Not established
The evidence for sulbutiamine is limited. For diabetic nerve pain (neuropathy), fatigue, and multiple sclerosis-related fatigue, the research we have isn't reliable enough to rate whether it works.
If you're considering it for one of these concerns, talk with your doctor about whether the current evidence supports a trial, and what other options may be better studied.
How safe is it?
Some data gaps
Short-term use at 600 mg has been used safely in limited research for up to 4 weeks. However, we don't have enough data on long-term safety — that's a real gap in what we know.
Side effects reported in individual patients include headache, insomnia, tremor, drowsiness, and nausea, but these are rare. The safety data advises against use during pregnancy and breastfeeding.
Meds to double-check
No known interactions
No interactions are documented in our data for sulbutiamine.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and some safety-information gaps remain.
Sulbutiamine may appeal to you if you're exploring options for fatigue or nerve-related symptoms and your doctor has suggested a trial. Because long-term safety isn't well established and effectiveness for these uses is unproven, this is one to discuss with your pharmacist or doctor first — especially if you plan to use it beyond a few weeks.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Sulbutiamine, straight from the product label.
| Brand | BulkSupplements.com |
|---|---|
| Net contents | 25 Gram(s); 0.88 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Oct 22, 2021 |
| DSLD ID | 254578 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Sulbutiamine by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Clean & pure bulk supplements
Precautions
Warning: Do not take this supplement if you have high blood pressure or are under 18 years of age.
This product is not intended for use by those with a serious medical condition or pregnant or lactating women.
Consult your physician before use.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Free of: Sugar, soy, dairy, yeast, gluten or additives
Suggested/Recommended/Usage/Directions
Directions: Take 200 milligrams once or twice daily, or as directed by a physician. Since the body forms a tolerance to this product, individual needs will vary. Use an accurate milligram scale to measure.
Storage
Storage: Keep dry, cool & dark
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Sulbutiamine by BulkSupplements.com label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Sulbutiamine by BulkSupplements.com
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size200 mg Dosage formPowder Servings per container125 Amounts shown are per serving.
Sulbutiamine
No knowninteractions
Sulbutiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) developed in Japan, often taken for fatigue and to support mental energy and foc...
Sulbutiamine monograph & interactionsOther (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.
Sulbutiamine by BulkSupplements.com Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Sulbutiamine. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Sulbutiamine, from the product label.
BulkSupplements.com
See all BulkSupplements.com products- Name
- BulkSupplements.com
- Street Address
- 7511 Eastgate Road
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Web Address
- BulkSupplements.com
Sulbutiamine by BulkSupplements.com: Common Questions
Does Sulbutiamine by BulkSupplements.com interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is sulbutiamine safe to take while I'm pregnant?
Can I take this while breastfeeding?
How long can I safely take sulbutiamine?
What side effects might I experience?
Does sulbutiamine actually work for fatigue or nerve pain?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Sulbutiamine is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Sulbutiamine’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Sulbutiamine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sulbutiamine 4 references
- Shah S. Adjuvant role of vitamin B analogue (sulbutiamine) with anti-infective treatment in infection associated asthenia. J Assoc Physicians India. 2003;51:891-5.
- Loo H, Poirier M, Ollat H, et al. [Effects of subutiamine (Arcalion 200) on psycho-behavioral inhibition in major depressive episodes]. Encephale. 2000;26(2):70-5.
- Kiew K, Wan Mohamad W, Ridzuan A, et al. Effects of sulbutiamine on diabetic polyneuropathy: an open randomized controlled study in type 2 diabetics. Malays J Med Sci. 2002;9(1):21-7.
- Sevim S, Kaleagasi H, Tasdelen B. Sulbutiamine shows promising results in reducing fatigue in patients with multiple sclerosis. Mult Scler Relat Disord. 2017;16:40-43. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC