No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Sulbutiamine Ingredients & Drug Interactions

by Pure Nootropics

Capsule Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Sulbutiamine is a dietary supplement by Pure Nootropics with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, memory and focus, mental clarity.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Sulbutiamine by Pure Nootropics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This is a straightforward single-ingredient product: one active ingredient, sulbutiamine, which is a synthetic form of thiamine (vitamin B1). Each capsule contains sulbutiamine in a capsule made with hypromellose and filled with microcrystalline cellulose and stearate acid as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Sulbutiamine product and its label doesn't state a use — see Sulbutiamine's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have reliable evidence that sulbutiamine works for diabetic neuropathy, general fatigue, or multiple sclerosis-related fatigue — the three conditions it's been studied for. The research on it isn't established enough for us to rate it either way.

If you're considering it for one of these purposes, talk with your doctor about what the current evidence actually supports.

The evidence, ingredient by ingredient Sulbutiamine

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sulbutiamine has been used at 600 mg daily for up to 4 weeks in small studies without major safety signals, but we don't know much about what happens if you take it long-term. A small number of trial participants reported headache, insomnia, tremor, drowsiness, or nausea — each showing up in just one person per symptom in the data we have.

The safety data advises against use during pregnancy and while breastfeeding because there isn't enough information to know it's safe.

Side effects, ingredient by ingredient Sulbutiamine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for this ingredient in our data. Always check your exact medications with the tool on this page before starting.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.

Sulbutiamine may appeal to you if you're exploring options for fatigue or nerve pain, but the evidence that it works isn't solid yet. Because safety data for long-term use is limited, this isn't a take-it-for-months-without-checking kind of supplement.

Talk with your pharmacist about whether it fits your situation and how long you plan to use it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sulbutiamine, straight from the product label.

Brand Pure Nootropics
Barcode (UPC) 00852388864
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 316607
Product type Vitamin
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sulbutiamine by Pure Nootropics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0 Not Present
Maximum serving Sizes:
0 Not Present
Servings per container
90
UPC/BARCODE
00852388864
IngredientAmount% DV
Sulbutiamine200 mg--

Other ingredients: Hypromellose, Microcrystalline Cellulose, Stearate Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Notice: This product is a chemical compound. All chemicals have risks. Please research and understand the associated risks before handling. Misuse of this product may result in adverse reactions.

Keep out of reach of children

FDA Disclaimer Statement

This product is not approved by the FDA.

Formulation

Quality tested

Storage

Store in a cool, dry place.

See for yourself

Sulbutiamine by Pure Nootropics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Sulbutiamine by Pure Nootropics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0 Not Present Dosage formCapsule Servings per container90 Amounts shown are per serving.

Sulbutiamine

No known
interactions
200 mg per serving

Sulbutiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) developed in Japan, often taken for fatigue and to support mental energy and foc...

Sulbutiamine monograph & interactions

Other (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Stearate Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sulbutiamine by Pure Nootropics Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Sulbutiamine. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Sulbutiamine, from the product label.

Pure Nootropics

See all Pure Nootropics products
Name
Pure Nootropics, LLC
Street Address
P.O. Box 6827
City
Albuquerque
State
NM
ZipCode
87197
Phone Number
424-738-0385
Web Address
purenootropics.net
Pharmacist Counseling Corner

Sulbutiamine by Pure Nootropics: Common Questions

Does Sulbutiamine by Pure Nootropics interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Sulbutiamine. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Sulbutiamine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is sulbutiamine safe to take while pregnant or breastfeeding?
The safety data advises against sulbutiamine during pregnancy and while breastfeeding — there isn't enough information to know it's safe. Talk with your doctor or pharmacist about your specific situation before use.
What are the side effects?
Headache, insomnia, tremor, drowsiness, and nausea have each been reported by a small number of people in trials. We know it's been used safely at 600 mg daily for up to 4 weeks, but long-term safety data is limited.
Does sulbutiamine actually work for fatigue?
We don't have reliable evidence that it works for general fatigue or fatigue from multiple sclerosis. The research on it isn't established enough to say yes or no.
How long can I safely take this?
It's been studied safely for up to 4 weeks, but we don't have good information about long-term use. Check with your pharmacist about how long you're planning to use it.
What is sulbutiamine?
Sulbutiamine is a synthetic form of thiamine, a B vitamin. It's been studied mainly for nerve pain in diabetes and various types of fatigue, but the evidence for those uses isn't solid.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sulbutiamine is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sulbutiamine label
Go deeper

The Full Monographs Behind Sulbutiamine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Sulbutiamine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sulbutiamine 4 references
  1. Shah S. Adjuvant role of vitamin B analogue (sulbutiamine) with anti-infective treatment in infection associated asthenia. J Assoc Physicians India. 2003;51:891-5.
  2. Loo H, Poirier M, Ollat H, et al. [Effects of subutiamine (Arcalion 200) on psycho-behavioral inhibition in major depressive episodes]. Encephale. 2000;26(2):70-5.
  3. Kiew K, Wan Mohamad W, Ridzuan A, et al. Effects of sulbutiamine on diabetic polyneuropathy: an open randomized controlled study in type 2 diabetics. Malays J Med Sci. 2002;9(1):21-7.
  4. Sevim S, Kaleagasi H, Tasdelen B. Sulbutiamine shows promising results in reducing fatigue in patients with multiple sclerosis. Mult Scler Relat Disord. 2017;16:40-43. PubMed

See these in context on the Sulbutiamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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