Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Super Beets Acai Berry Flavor Ingredients & Drug Interactions

by Human N

Other (e.g. Tea Bag) Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Super Beets Acai Berry Flavor is a dietary supplement by Human N with 3 active ingredients. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 1,041 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Enovita, Beet, Powder, Coenzyme Q-10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Super Beets Acai Berry Flavor by Human N

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Super Beets contains 3 active ingredients. Coenzyme Q-10 is an antioxidant your cells naturally make and use for energy production.

Beet powder comes from beets and contains nitrates and pigments called betalains. The third ingredient, Enovita, is a grape extract — we hold data on it as grape — which contains polyphenols and proanthocyanidins.

The rest of the ingredient list is inactive: sweeteners (cane sugar, tapioca syrup, rebiana), binders and texture agents (rice bran, sunflower lecithin, glycerin), flavoring, juices, acids, and oil.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: blood pressure support and heart health.
  • We looked for evidence on: Hypertension, Cardiovascular disease (CVD), Coronary heart disease (CHD), Congestive heart failure (CHF), Dyslipidemia, Hypercholesterolemia — and 4 related terms.
  • The strongest evidence on file: Coenzyme Q10 is rated "Possibly Effective" for Congestive heart failure (CHF) (Natural Medicines).
  • Also on file: Coenzyme Q10 is rated "Possibly Effective" for Myocardial infarction (MI).
  • Also on file: Beet is rated "Insufficient Reliable Evidence To Rate" for Coronary heart disease (CHD), Dyslipidemia, Hypertension, Pregnancy-induced hypertension, and more.

For coenzyme Q-10, the evidence is strongest for treating coenzyme Q-10 deficiency (likely effective). It's possibly effective for fibromyalgia, migraine headache, congestive heart failure, and diabetic neuropathy — meaning some studies show benefit, but the evidence isn't yet conclusive.

Beet powder is possibly effective for athletic performance and exercise-induced muscle soreness. Grape extract is possibly effective for chronic venous insufficiency (a circulation condition), but was rated possibly ineffective for nausea from chemotherapy, hay fever, and obesity.

The data we hold doesn't establish effectiveness for many other claims — those ratings fall into insufficient evidence or lack of reliable data.

The evidence, ingredient by ingredient Coenzyme Q10 Beet Grape

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Coenzyme Q-10 is generally well tolerated. The most common side effects are gastrointestinal — appetite suppression, diarrhea, heartburn, nausea — occurring in less than 1% of people.

Headache, dizziness, insomnia, and skin itching have been reported rarely. Beet powder is safe as a food; concentrated supplements lack sufficient safety data, so use with caution.

The most common effect is harmless red or black coloring of stools. Rare serious effects from large amounts include low calcium and kidney damage.

Grape as food is safe; concentrated supplements are generally well tolerated, though some people report abdominal pain, diarrhea, headache, nausea, and joint pain. For pregnancy, concentrated grape supplements and grape wine should be avoided due to limited safety data.

For breastfeeding, there isn't enough data on concentrated supplements of any of these ingredients — talk with your doctor or pharmacist.

Side effects, ingredient by ingredient Coenzyme Q10 Beet Grape

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Beet, Grape, Coenzyme Q10.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 1,042 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting this product, check with your pharmacist if you take chemotherapy drugs (particularly alkylating agents like cyclophosphamide), blood thinners or antiplatelet medications (warfarin, apixaban, clopidogrel), blood pressure drugs, or any medication processed by your liver's CYP3A4, CYP2D6, CYP2E1, or CYP1A2 pathways. The coenzyme Q-10 and both plant extracts interact with multiple drug categories.

A pharmacist can review your specific medications against the interaction database on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is worth discussing with your pharmacist or doctor if you're interested in coenzyme Q-10 for heart health or migraine, or beet extract for exercise performance. Skip it or get personalized medical advice if you take chemotherapy drugs, blood thinners like warfarin, blood pressure medications, or drugs metabolized through CYP3A4, CYP2D6, or related pathways.

If you're pregnant or breastfeeding, check with your doctor first — there isn't enough safety data on these concentrated supplements.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Super Beets Acai Berry Flavor, straight from the product label.

Brand Human N
Barcode (UPC) 813188021169
Net contents 60 Chew(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 334061
Product type Other Combinations
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Super Beets Acai Berry Flavor by Human N, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Chew(s)
Maximum serving Sizes:
2 Chew(s)
Servings per container
30
UPC/BARCODE
813188021169
IngredientAmount% DV
Calories40 Calorie(s)--
Total Carbohydrates9 Gram(s)3%
Added Sugars5 Gram(s)10%
Total Sugars5 Gram(s)--
Coenzyme Q-10100 mg--
Beet, Powder500 mg--
Enovita150 mg--

Other ingredients: Cane Sugar, Raw, Tapioca Syrup, Rice Bran, Natural Flavors, Sunflower Lecithin, Fruit Juice, Vegetable Juice, Sunflower Oil, Malic Acid, Glycerin, Citric Acid, Rebiana

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Heart chews advanced Advanced blood pressure support

Heart healthy energy support Healthy blood circulation support

Nearly 2x more effective healthy blood pressure support than diet and exercise alone clinically researched grape seed extract. In a 16-week, double-blind, placebo-controlled study involving 119 healthy men and women, Heart Chews polyphenol compound, taken as part of a healthy lifestyle was clinically shown nearly 2-times as effective at promoting normal blood pressure already in the normal range as a healthy lifestyle alone.

Plant-based

Gluten free Non-GOM No artificial sweeteners synthetic colors.

Formula

3-in-1 formula with CoQ10 Acai Berry Flavor

Superbeets heart chews advanced features non-GMO beetroot plus clinically researched grape seed extract to support healthy blood pressure, heart healthy energy without caffeine or stimulants, and healthy circulation and blood flow. CoQ10 is added to help support cellular energy production and vascular health. In a 16-week, double-blind, placebo-controlled study involving 119 healthy men and women, Heart Chews polyphenol compound, taken as part of a healthy lifestyle was clinically shown nearly 2-times as effective at promoting normal blood pressure already in the normal range as a healthy lifestyle alone.

FDA Statement of Identity

Dietary Supplement

General Statements

#1 Doctor, pharmacist & cardiologist recommended beet brand for heart health support According to IQVIA ProVoice survey 2023

Join our community for exclusive giveaways, education, and access. For more information visit HumanN.com 855-636-4040 Please recycle

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take two (2) chews daily.

Precautions

Precaution: For adult use only. Keep out of reach of children.

Consult a physician if you are pregnant/nursing, taking medications or have a medical condition.

Brand IP Statement(s)

Enovita is a registered trademark of Indena S.p.A Copyright 2024 Human Power of N All rights reserved

Seals/Symbols

Made in the USA with globally sourced ingredients.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Super Beets Acai Berry Flavor by Human N label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Super Beets Acai Berry Flavor by Human N

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Chew(s) Dosage formOther (e.g. Tea Bag) Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Coenzyme Q-10

Interacts with
198 drugs
100 mg per serving Form: Ubidecarenone

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

Coenzyme Q-10 monograph & interactions

Beet, Powder

Interacts with
861 drugs
500 mg per serving

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Beet, Powder monograph & interactions

Enovita

Interacts with
910 drugs
150 mg per serving Form: Grape Seed Extract

Grapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support heart and b...

Enovita monograph & interactions

Other (inactive) ingredients: Cane Sugar, Raw, Tapioca Syrup, Rice Bran, Natural Flavors, Sunflower Lecithin, Fruit Juice, Vegetable Juice, Sunflower Oil, Malic Acid, Glycerin, Citric Acid, Rebiana. These complete the product’s ingredient list but are not active constituents.

Interaction report

Super Beets Acai Berry Flavor by Human N Drug Interactions

Want to check YOUR meds against Super Beets Acai Berry Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,041Drugs
884 Moderate 157 Minor

Ingredients driving the most interactions

Enovita 910

Each ingredient & the kinds of drugs it affects

For each ingredient in Super Beets Acai Berry Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Enovita9 drug types · 910 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro evidence suggests that grape extracts might decrease platelet aggregation.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

Ingesting grape juice with cyclosporine can reduce cyclosporine absorption.
A small pharmacokinetic study in healthy young adults shows that intake of purple grape juice 200 mL along with cyclosporine can decrease the absorption of cyclosporine by up to 30% when compared with water. Separate doses of grape juice and cyclosporine by at least 2 hours to avoid this interaction.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
A small pharmacokinetic study in healthy adults shows that ingestion of 200 mL of grape juice decreases phenacetin plasma levels. This is thought to be due to induction of CYP1A2.

Likelihood Possible Evidence B
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, grape seed extract may increase the levels of CYP2D6 substrates.
In vitro evidence suggests that grape seed extract might inhibit CYP2D6 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
In vitro and animal research suggests that grape seed proanthocyanidin extract inhibits CYP2E1 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
In vitro evidence suggests that grape seed extract might inhibit CYP3A4 enzymes. However, evidence from animal research shows that grape seed extract may induce CYP3A4 in the liver. So far, these interactions have not been reported in humans.

Likelihood Possible Evidence D
Midazolam (Versed)

Theoretically, long-term intake of grape seed extract might decrease the effects of midazolam.
Animal research shows that subchronic ingestions of grape seed extract can increase the elimination of intravenous midazolam by increasing hepatic CYP3A4 activity. Single doses of grape seed extract do not appear to affect midazolam elimination.

Likelihood Possible Evidence D
Phenacetin

Grape juice might decrease phenacetin absorption.
A small pharmacokinetic study in healthy adults shows that ingestion of 200 mL of grape juice decreases phenacetin plasma levels. This is thought to be due to induction of cytochrome P450 1A2 (CYP1A2).

Likelihood Possible Evidence B
Cytochrome P450 2C9 (Cyp2C9) Substrates

It is unclear if grape juice or grape seed extract inhibits CYP2C9; research is conflicting.
In vitro evidence shows that grape seed extract or grape juice might inhibit CYP2C9 enzymes. However, a small pharmacokinetic study in healthy adults shows that drinking 8 ounces of grape juice once does not affect the clearance of flurbiprofen, a probe-drug for CYP2C9 metabolism. The effects of continued grape juice consumption are unclear.

Likelihood Unlikely Evidence D

Beet, Powder3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D

Coenzyme Q-103 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Super Beets Acai Berry Flavor, from the product label.

Human N

See all Human N products
Name
Human Power of N
Street Address
1250 S. Capital of Texas Hwy, Building 1 Suite 360
City
Austin
State
TX
ZipCode
78746
Phone Number
855-636-4040
Web Address
HumanN.com
Pharmacist Counseling Corner

Super Beets Acai Berry Flavor by Human N: Common Questions

Does Super Beets Acai Berry Flavor by Human N interact with any medications?
Yes. Based on its ingredients, Super Beets Acai Berry Flavor has a known interaction with 1,041 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Super Beets Acai Berry Flavor contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does coenzyme Q-10 actually do in my body?
Coenzyme Q-10 is a compound your cells naturally produce and use to generate energy. It also acts as an antioxidant. Your body makes less of it as you age, which is why some people supplement it — especially for heart health, migraines, and muscle disorders. The evidence is strongest for treating an actual Q-10 deficiency.
Will this product lower my blood pressure?
Possibly, though the evidence is mixed. Coenzyme Q-10 and beet both contain compounds that may lower blood pressure in some people. If you already take blood pressure medication, that's one reason to discuss this product with your pharmacist first — the combined effect could be too strong.
Why are my stools red after taking this?
That's the beet powder. Beets contain natural pigments that turn your stool red or even black — it's completely harmless and normal. The color will go away once you stop taking the product.
Is it safe to take this while breastfeeding?
There isn't enough safety data on concentrated supplements of any of these three ingredients while breastfeeding. Talk with your doctor or pharmacist about whether it's right for you — they can give you personalized advice based on your situation.
Can I take this with my statin or heart medication?
That depends on your specific drug. Coenzyme Q-10 and beet both interact with medications processed through your liver in ways that can raise or lower drug levels. Use the interaction checker on this page with your exact medication names, or ask your pharmacist to review it for you.
What does the 'Enovita' ingredient do?
Enovita is a grape extract containing polyphenols and other compounds. In the data we hold, it's rated possibly effective for chronic venous insufficiency, a circulation condition. Like other grape extracts, it can interact with several medications, so it's important to check before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Super Beets Acai Berry Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Super Beets Acai Berry Flavor label
Sources

Sources & How We Checked

Super Beets Acai Berry Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 88 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Coenzyme Q10 40 references
  1. Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
  2. Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
  3. Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
  4. Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
  5. Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
  6. Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
  7. Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
  8. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  9. Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
  10. Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
  11. Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
  12. The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
  13. Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
  14. Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
  15. Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
  16. Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
  17. Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
  18. Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
  19. Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
  20. Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
  21. Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
  22. Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
  23. Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
  24. Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
  25. Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
  26. Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
  27. Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
  28. Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
  29. Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
  30. Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
  31. Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
  32. Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
  33. Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
  34. Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
  35. Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
  36. Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
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  38. Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: A systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2022;13:883251. PubMed
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Beet 14 references
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  10. Schaefer, E., Peil, H., Ambrosetti, L., and Petrini, O. Oedema protective properties of the red vine leaf extract AS 195 (Folia vitis viniferae) in the treatment of chronic venous insufficiency. A 6-week observational clinical trial. Arzneimittelforschun PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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