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Dietary supplement

Super Beta Carotene 25,000 IU (7,500 mcg RAE) Ingredients & Drug Interactions

by Carlson

Softgel Capsule Category: Vitamin
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Super Beta Carotene 25,000 IU (7,500 mcg RAE) is a dietary supplement by Carlson with 1 active ingredient. Its ingredients are commonly taken for eye and vision health, skin health and acne, immune support.Based on those ingredients, 387 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin A. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Super Beta Carotene 25,000 IU (7,500 mcg RAE) by Carlson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is a single-ingredient supplement: vitamin A (as beta carotene), delivering 25,000 IU (7,500 mcg RAE — retinol activity equivalent) per softgel. The inactive ingredients are soybean oil, softgel shell, beeswax, and soy lecithin.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Vision support, immune function, and skin health.
  • We looked for evidence on: Night vision, Vitamin A deficiency, Cataracts, Corneal abrasion, Photoreactive keratectomy, Retinitis pigmentosa — and 4 related terms.
  • The strongest evidence on file: Vitamin A is rated "Effective" for Vitamin A deficiency (Natural Medicines).
  • Also on file: Vitamin A is rated "Possibly Effective" for Aging skin, Night vision, Retinitis pigmentosa.
  • Also on file: Vitamin A is rated "Insufficient Reliable Evidence To Rate" for Acne, Cataracts, Atopic dermatitis (eczema).

Vitamin A is effective for preventing and treating vitamin A deficiency. It's possibly effective for oral leukoplakia (a precancerous mouth condition), aging skin, measles, ulcerative colitis, and bronchopulmonary dysplasia (a chronic lung condition in premature infants).

The evidence for these other uses is less established than for deficiency.

The evidence, ingredient by ingredient Vitamin A

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin A is generally well tolerated at recommended doses, but it accumulates in your body and high doses are toxic. Serious effects from very high doses — though rare — include a condition called pseudotumor cerebri (swelling around the brain), liver damage, and in extreme cases, coma or death.

Chronic use of large amounts causes symptoms like fatigue, dry and cracking skin, hair loss, and brittle nails. Young children are more vulnerable to toxicity from a single large dose than adults are.

Vitamin A safety in pregnancy and lactation is mixed in the data we hold — some sources rate it likely safe and others possibly unsafe. Because high-dose vitamin A (especially as retinol) carries a real risk of birth defects, pregnant people or those planning pregnancy should talk with their doctor or pharmacist before taking any vitamin A supplement above the recommended dietary amount.

Side effects, ingredient by ingredient Vitamin A

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin A.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 388 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take retinoid drugs (Major severity) — these include prescription acne and skin medications like tretinoin and isotretinoin. Also confirm any use of blood thinners (Moderate), tetracycline antibiotics (Moderate), or medications that can affect your liver (Moderate).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This supplement is useful if you're deficient in vitamin A or treating one of the conditions it's shown to help. Because vitamin A toxicity is dose-dependent and builds up over time, stick to the recommended amount and avoid combining it with retinoid medications, blood thinners, or tetracycline antibiotics without guidance from your doctor or pharmacist.

If you're pregnant, breastfeeding, or take any prescription medications, check with your own healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Super Beta Carotene 25,000 IU (7,500 mcg RAE), straight from the product label.

Brand Carlson
Barcode (UPC) 088395011825
Net contents 250 Softgel(s)
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 241720
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Super Beta Carotene 25,000 IU (7,500 mcg RAE) by Carlson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
250
UPC/BARCODE
088395011825
IngredientAmount% DV
Vitamin A7500 mcg RAE833%

Other ingredients: Soybean Oil, Softgel Shell, Beeswax, Soy Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Formulation

Vision support Immune function Skin health

Gluten-free No artificial preservatives

Potency & quality guaranteed An FDA regulated facility

General Statements

Carlson providing the highest quality nutritional supplements since 1965

Suggested/Recommended/Usage/Directions

Directions: Adults: take one soft gel daily at mealtime.

Formula

Super Beta Carotene provides powerful antioxidant support for the whole body and boosts immune and vision health. Beta Carotene is a carotenoid found in many fruits and vegetables, and gives carrots their orange color. Beta Carotene can be converted to vitamin A by our body as needed, and does not accumulate in our liver-making it a safe, effective source of vitamin A.

See for yourself

Super Beta Carotene 25,000 IU (7,500 mcg RAE) by Carlson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Super Beta Carotene 25,000 IU (7,500 mcg RAE) by Carlson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container250 Amounts shown are per serving.

Vitamin A

Interacts with
387 drugs
7500 mcg RAE per serving Form: Beta-Carotene

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplemen...

Vitamin A monograph & interactions

Other (inactive) ingredients: Soybean Oil, Softgel Shell, Beeswax, Soy Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Super Beta Carotene 25,000 IU (7,500 mcg RAE) by Carlson Drug Interactions

Want to check YOUR meds against Super Beta Carotene 25,000 IU (7,500 mcg RAE)?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
387Drugs
9 Major 378 Moderate

Ingredients driving the most interactions

Vitamin A 387

Each ingredient & the kinds of drugs it affects

For each ingredient in Super Beta Carotene 25,000 IU (7,500 mcg RAE) with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin A4 drug types · 387 drugs

Retinoids

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.
Retinoids, which are vitamin A derivatives, could have additive toxic effects when taken with vitamin A supplements.

Likelihood Probable Evidence D
Hepatotoxic Drugs

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.
The tolerable upper intake level (UL) is the highest level of intake that is likely to pose no risk of adverse effects. Doses of vitamin A above the UL can cause hepatotoxicity, ranging from elevated liver enzymes to liver failure.

Likelihood Possible Evidence C
Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with high doses of vitamin A can increase the risk of pseudotumor cerebri.
Benign intracranial hypertension (pseudotumor cerebri) can occur with tetracyclines and with acute or chronic vitamin A toxicity. Case reports suggest that taking tetracyclines and vitamin A concurrently can increase the risk of this condition. Avoid high doses of vitamin A in people taking tetracyclines chronically.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, high doses of vitamin A could increase the risk of bleeding with warfarin.
Vitamin A toxicity is associated with hemorrhage and hypoprothrombinemia, possibly due to vitamin K antagonism. Advise patients taking warfarin to avoid doses of vitamin A above the tolerable upper intake level of 10,000 IU/day for adults.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Super Beta Carotene 25,000 IU (7,500 mcg RAE), from the product label.

Carlson

See all Carlson products
Name
Carlson Division of J.R. Carlson Laboratories, Inc.
City
Arlington Heights
State
IL
ZipCode
60004
Phone Number
888-234-5656
Web Address
www.carlsonlabs.com
Pharmacist Counseling Corner

Super Beta Carotene 25,000 IU (7,500 mcg RAE) by Carlson: Common Questions

Does Super Beta Carotene 25,000 IU (7,500 mcg RAE) by Carlson interact with any medications?
Yes. Based on its ingredients, Super Beta Carotene 25,000 IU (7,500 mcg RAE) has a known interaction with 387 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Super Beta Carotene 25,000 IU (7,500 mcg RAE) contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The data we hold is mixed — some sources rate it likely safe and others possibly unsafe in pregnancy. High-dose vitamin A (especially as retinol) carries a real risk of birth defects, so talk with your doctor or pharmacist before taking any vitamin A supplement above normal dietary amounts if you're pregnant, trying to conceive, or breastfeeding.
What does vitamin A do in the body?
Vitamin A is essential for vision, immune function, skin health, and growth. This product is effective for treating vitamin A deficiency and possibly helpful for oral leukoplakia, aging skin, measles, ulcerative colitis, and bronchopulmonary dysplasia.
What are the side effects of taking too much?
Vitamin A builds up in your body, and high doses cause toxicity with symptoms like fatigue, dry cracking skin, hair loss, brittle nails, and skin rashes. In very high doses, it can cause a condition called pseudotumor cerebri (swelling around the brain), liver damage, and rarely, coma or death. Young children are especially vulnerable to toxicity.
How much vitamin A is safe?
The tolerable upper intake level (UL) — the highest amount unlikely to cause harm — is 10,000 IU per day for adults. This product contains 25,000 IU, so it should only be taken as directed or under a healthcare provider's guidance, not as a daily multivitamin.
Does this product contain soy?
Yes — the inactive ingredients include soybean oil and soy lecithin. If you have a soy allergy, talk with your pharmacist before taking it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Super Beta Carotene 25,000 IU (7,500 mcg RAE) is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Super Beta Carotene 25,000 IU (7,500 mcg RAE) label
Go deeper

The Full Monographs Behind Super Beta Carotene 25,000 IU (7,500 mcg RAE)’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Super Beta Carotene 25,000 IU (7,500 mcg RAE)'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 31 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin A 31 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Griffiths JK. The vitamin A paradox. J Pediatr 2000;137:604-7.. PubMed
  3. Hardman JG, Limbird LL, Molinoff PB, eds. Goodman and Gillman's The Pharmacological Basis of Therapeutics, 9th ed. New York, NY: McGraw-Hill, 1996.
  4. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  5. FDA Talk Paper. Vitamin A and birth defects (T95-56). Food and Drug Administration, U.S. Department of Health and Human Services, Rockville, MD. October 6, 1995.
  6. Russell RM. The vitamin A spectrum: from deficiency to toxicity. Am J Clin Nutr 2000;71:878-84. PubMed
  7. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  8. Feskanich D, Singh V, Willett WC, Colditz GA. Vitamin A intake and hip fractures among postmenopausal women. JAMA 2002;287:47-54. PubMed
  9. Melhus H, Michaelsson K, Kindmark A, et al. Excessive dietary intake of vitamin A is associated with reduced bone mineral density and increased risk for hip fracture. Ann Intern Med 1998;129:770-8. PubMed
  10. Michaelsson K, Lithell H, Vessby B, Melhus H. Serum retinol levels and the risk of fracture. N Engl J Med 2003;348:287-94.. PubMed
  11. Botterweck AA, van den Brandt PA, Goldbohm RA. Vitamins, carotenoids, dietary fiber, and the risk of gastric carcinoma: results from a prospective study after 6.3 years of follow-up. Cancer 2000;88:737-48.. DOI
  12. Meyskens FL Jr, Graham V, Chvapil M, et al. A phase I trial of beta-all-trans-retinoic acid delivered via a collagen sponge and a cervical cap for mild or moderate intraepithelial cervical neoplasia. J Natl Cancer Inst 1983;71:921-5..
  13. Hathcock JN, Hattan DG, Jenkins MY, et al. Evaluation of vitamin A toxicity. Am J Clin Nutr 1990;52:183-202.. PubMed
  14. Walters BN, Gubbay SS. Tetracycline and benign intracranial hypertension: report of five cases. Br Med J 1981;282:19-20.. PubMed
  15. Pearson MG, Littlewood SM, Bowden AN. Tetracycline and benign intracranial hypertension (letter). Br Med J 1981;282:568-9.. PubMed
  16. Azais-Braesco V, Pascal G. Vitamin A in pregnancy: requirements and safety limits. Am J Clin Nutr 2000;71:1325S-33S. PubMed
  17. Smedts HP, de Vries JH, Rakhshandehroo M, et al. High maternal vitamin E intake by diet or supplements is associated with congenital heart defects in the offspring. BJOG 2009;116:416-23. PubMed
  18. Grotto, I., Mimouni, M., Gdalevich, M., and Mimouni, D. Vitamin A supplementation and childhood morbidity from diarrhea and respiratory infections: a meta-analysis. J Pediatr 2003;142(3):297-304. PubMed
  19. Mahalanabis, D., Lahiri, M., Paul, D., Gupta, S., Gupta, A., Wahed, M. A., and Khaled, M. A. Randomized, double-blind, placebo-controlled clinical trial of the efficacy of treatment with zinc or vitamin A in infants and young children with severe acute l
  20. Long, K. Z., Montoya, Y., Hertzmark, E., Santos, J. I., and Rosado, J. L. A double-blind, randomized, clinical trial of the effect of vitamin A and zinc supplementation on diarrheal disease and respiratory tract infections in children in Mexico City, Mex
  21. Fritz, H., Kennedy, D., Fergusson, D., Fernandes, R., Doucette, S., Cooley, K., Seely, A., Sagar, S., Wong, R., and Seely, D. Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis. PLoS.One. 2011;6(6):e21107. PubMed
  22. Mayo-Wilson, E., Imdad, A., Herzer, K., Yakoob, M. Y., and Bhutta, Z. A. Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis. BMJ 2011;343:d5094. PubMed
  23. Mazumder S, Taneja S, Bhatia K, Yoshida S, Kaur J, Dube B, Toteja GS, Bahl R, Fontaine O, Martines J, Bhandari N; Neovita India Study Group. Efficacy of early neonatal supplementation with vitamin A to reduce mortality in infancy in Haryana, India (Neovit
  24. Baineni R, Gulati R, Delhi CK. Vitamin A toxicity presenting as bone pain. Arch Dis Child. 2017;102(6):556-8. PubMed
  25. Darlow BA, Graham PJ, Rojas-Reyes MX. Vitamin A supplementation to prevent mortality and short- and long-term morbidity in very low birth weight infants. Cochrane Database Syst Rev. 2016;(8):CD000501. PubMed
  26. Haider BA, Sharma R, Bhutta ZA. Neonatal vitamin A supplementation for the prevention of mortality and morbidity in term neonates in low and middle income countries. Cochrane Database Syst Rev. 2017;2:CD006980. PubMed
  27. Mohammad YM, Raslan IR, Al-Hussain FA. Idiopathic Intracranial Hypertension Induced by Topical Application of Vitamin A. J Neuroophthalmol. 2016;36(4):412-3. PubMed
  28. Masnadi Shirazi K, Nikniaz Z, Masnadi Shirazi A, Rohani M. Vitamin A supplementation decreases disease activity index in patients with ulcerative colitis: A randomized controlled clinical trial. Complement Ther Med. 2018 Dec;41:215-219. PubMed
  29. Ding Y, Hu P, Yang Y, et al. Impact of maternal daily oral low-dose vitamin A supplementation on the mother-infant pair: a randomised placebo-controlled trial in China. Nutrients 2021;13(7):2370. PubMed
  30. Knapik JJ, Hoedebecke SS. Vitamin A and bone fractures: systematic review and meta-analysis. J Spec Oper Med 2021;21(2):100-7. PubMed
  31. Imdad A, Mayo-Wilson E, Haykal MR, et al. Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age. Cochrane Database Syst Rev 2022;3(3):CD008524. PubMed

See these in context on the Vitamin A monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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