Interactions on record — worth a quick check against your medications. Based on 3 of 14 ingredients. Check your meds →
Dietary supplement

Super Strength Digestion Ingredients & Drug Interactions

by Theramedix BioSET

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Super Strength Digestion is a dietary supplement by Theramedix BioSET with 14 active ingredients. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Protease Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Super Strength Digestion by Theramedix BioSET

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 14 active ingredients.
  • “Proprietary Enzyme Blend” is a proprietary blend — the label gives one combined amount (484 mg) without saying how much of each component you get.

This product is a multi-enzyme digestive formula with 14 active ingredients. Lactase breaks down milk sugar (lactose); lipase works on fats; and the remaining enzymes target different carbohydrates and proteins in your food.

The capsule itself is made from hypromellose and water.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: broad-spectrum digestive aid for proteins, fats, carbohydrates, fiber.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, Indigestion, Bloating, Malabsorption, Food intolerance.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

Lactase is effective for lactose intolerance — that's well established. For everything else in this formula, the evidence isn't solid enough to rate.

Lipase and lactase have insufficient reliable evidence for colic and prematurity. The effectiveness of the other 12 enzymes in this product hasn't been established in the data we hold.

The evidence, ingredient by ingredient Lactase Papain Lipase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase is generally well tolerated, though a rare case of allergic reaction in a worker exposed to powdered lactase has been reported; if you have a known enzyme allergy, mention it to your pharmacist. Lactase is likely safe in pregnancy and lactation.

Lipase is generally well tolerated in supplement form, but people with serious digestive conditions should use it only under medical guidance. Safety data on lipase during pregnancy and breastfeeding is limited — if you're pregnant or nursing, talk with your doctor first.

Serious effects (like gastrointestinal damage) have been reported only in premature infants given a recombinant form in their formula or breast milk, not in adults taking oral supplements.

Side effects, ingredient by ingredient Lactase Papain Lipase

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 3 matched ingredients can interact with medications — Papain.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

No interactions are documented in our data for the ingredients we could check. However, we could not verify 12 of the 14 ingredients, so use the search tool on this page with your exact medication names to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a broad-spectrum digestive enzyme blend most useful if you have trouble digesting dairy (lactase is proven for that) or think you need enzyme support for other foods. If you have a serious digestive condition or are pregnant or breastfeeding, check with your doctor before starting.

Run any medications you take through the checker below.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 14 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Super Strength Digestion, straight from the product label.

Brand Theramedix BioSET
Barcode (UPC) 738676954098
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 321760
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Super Strength Digestion by Theramedix BioSET, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
738676954098
IngredientAmount% DV
Lactase0 NP--
Cellulase0 NP--
Invertase0 NP--
Glucoamylase0 NP--
Alpha-Galactosidase0 NP--
Xylanase0 NP--
Pectinase0 NP--
Beta-Glucanase0 NP--
Hemicellulase0 NP--
Diastase0 NP--
Proprietary Enzyme Blend484 mg--
Amylase0 NP--
Protease Blend0 NP--
Biodiastase 200085 mg--
Lipase0 NP--

Other ingredients: Hypromellose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Super Strength Digestion is the most powerful digestive enzyme on the market. It is a broad-spectrum digestive aid and has been formulated to assist in digesting proteins, fats, carbohydrates and fiber.

Absolutely no fillers added

Professional strength formula

Powerful digestive aid

Vegetarian

Optimizing enzyme potential

Suggested/Recommended/Usage/Directions

Recommended Usage: Take 1 capsule before each meal or snack.

Formula

Exclusive Thera-Blend formulation Thera-Blend is our exclusive process for formulating enzyme blends. These blends are formulated using multiple enzyme forms selected for their ability to break down numerous bonds in varying pH levels.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Keep out of reach of children

Storage

Store tightly closed in a cool, dry place.

Do not expose to excessive heat.

FDA Statement of Identity

Dietary Supplement

See for yourself

Super Strength Digestion by Theramedix BioSET label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Super Strength Digestion by Theramedix BioSET

These are the 14 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Enzyme Blend

484 mg per serving
  • Lactase
  • › Cellulase
  • › Invertase
  • › Glucoamylase
  • › Alpha-Galactosidase
  • › Xylanase
  • › Pectinase
  • › Beta-Glucanase
  • › Hemicellulase
  • › Diastase
  • › Amylase
  • Protease Blend
  • › Biodiastase 2000
  • Lipase

Other (inactive) ingredients: Hypromellose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Super Strength Digestion by Theramedix BioSET Drug Interactions

Want to check YOUR meds against Super Strength Digestion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2Drugs
2 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Super Strength Digestion with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Protease Blend1 drug type · 2 drugs

Warfarin (Coumadin)

Theoretically, papain might increase the effects and side effects of warfarin.
In one case report, a patient previously stable on warfarin was found to have an international normalization ratio (INR) of 7.4, which was attributed to ingestion of a supplement containing papain from papaya extract.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Super Strength Digestion, from the product label.

Theramedix BioSET

See all Theramedix BioSET products
Name
Theramedix BioSET
Street Address
2000 Highway 29 S
City
Anderson
State
SC
ZipCode
29626
Phone Number
877-246-7381
Web Address
www.theramedixbioset.com
Pharmacist Counseling Corner

Super Strength Digestion by Theramedix BioSET: Common Questions

Does Super Strength Digestion by Theramedix BioSET interact with any medications?
Yes. Based on its ingredients, Super Strength Digestion has a known interaction with 2 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Super Strength Digestion contains 14 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with lactose intolerance?
Yes — the lactase in this product is proven effective for lactose intolerance. The rest of the formula's effectiveness for other digestive issues isn't well established in the data we have.
Is lactase safe if I'm allergic to enzymes?
A rare case of allergic reaction to powdered lactase has been reported in someone occupationally exposed. If you have a known enzyme allergy, mention it to your pharmacist before taking this product.
Can I take this while pregnant?
Lactase is likely safe in pregnancy. Lipase has limited safety data during pregnancy, so if you're pregnant, talk with your doctor before starting to make sure it's right for you.
Is this safe for breastfeeding?
Lactase is likely safe while breastfeeding. Lipase safety during breastfeeding hasn't been well studied, so check with your healthcare provider first.
What do all these different enzymes do?
They break down different components of food — lactase handles milk sugar, lipase breaks down fats, and the others target various carbohydrates and proteins. Together they're meant to ease digestion.
Are there any side effects I should watch for?
Lactase and lipase are generally well tolerated with no common reported side effects in adults. If you have a serious digestive condition, use this only under medical guidance.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Super Strength Digestion is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Super Strength Digestion label
Sources

Sources & How We Checked

Super Strength Digestion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Papain 11 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Saf 1997;17:342-56.
  3. Shuttleworth D, Hill S, Marks R, Connelly DM. Relief of experimentally induced pruritus with a novel eutectic mixture of local anaesthetic agents. Br J Dermatol 1988;119:535-40.
  4. Mansfield LE, Ting S, Haverly RW, Yoo TJ. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge. Ann Allergy 1985;55:541-3.
  5. Martin, T., Uhder, K., Kurek, R., Roeddiger, S., Schneider, L., Vogt, H. G., Heyd, R., and Zamboglou, N. Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial PubMed
  6. Walker-Renard, P. Update on the medicinal management of phytobezoars. Am J Gastroenterol. 1993;88(10):1663-1666.
  7. Tymoszuk D, Wiszniewska M, Walusiak-Skorupa J. Papain-induced occupational rhinoconjunctivitis and asthma - A case report. Med Pr 2016;67(1):109-12. PubMed
  8. Soto-Mera MT, López-Rico MR, Filgueira JF, et al. Occupational allergy to papain. Allergy 2000;55(10):983-4. PubMed
  9. Tarlo SM, Shaikh W, Bell B, et al. Papain-induced allergic reactions. Clin Allergy 1978;8(3):207-15. PubMed
  10. Baur X, König G, Bencze K, Fruhmann G. Clinical symptoms and results of skin test, RAST and bronchial provocation test in thirty-three papain workers: Evidence for strong immunogenic potency and clinically relevant proteolytic e?ects of airborne papain. C
  11. Novey HS, Keenan WJ, Fairshter RD, Wells ID, Wilson AF, Culver BD. Pulmonary disease in workers exposed to papain: clinico-physiological and immunological studies. Clin Allergy 1980;10(6):721-31. PubMed

See these in context on the Papain monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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