Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Fat/High Lipase Digestion Ingredients & Drug Interactions

by Theramedix BioSET

Fat/High Lipase Digestion label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Fat/High Lipase Digestion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Fat/High Lipase Digestion is a dietary supplement by Theramedix BioSET with 4 active ingredients. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Protease Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Fat/High Lipase Digestion by Theramedix BioSET

Ask about any prescription or over-the-counter medication and we check it for interactions with Fat/High Lipase Digestion by Theramedix BioSET — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Fat/High Lipase Digestion by Theramedix BioSET

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Proprietary Enzyme Blend” is a proprietary blend — the label gives one combined amount (302 mg) without saying how much of each component you get.

This product has four active ingredients designed to help break down fats and other nutrients. Lactase works on lactose (milk sugar), Lipase targets fats, Amylase breaks down starches, and Protease handles proteins.

The Proprietary Enzyme Blend combines some of these into a single concentrated formula. Two inactive ingredients — Hypromellose and water — are used to form and fill the capsule.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: aids proper digestion of fats, carbs, protein, dairy.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, Pancreatic enzyme insufficiency, Fat malabsorption, Postprandial bloating.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

Lactase is effective for lactose intolerance, the difficulty digesting milk sugar. For the other ingredients and uses listed — Lipase and Amylase for dyspepsia (indigestion) or inflammatory bowel disease, and Lactase for colic or premature infant digestion — the evidence we hold is insufficient to rate whether they work.

If you're considering this for one of those conditions, talk with your pharmacist or doctor about what the current evidence shows.

The evidence, ingredient by ingredient Lactase Papain Lipase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase is rated likely safe in pregnancy and lactation. Lipase has little safety data in pregnancy, so use only if your doctor advises it, and safety while breastfeeding hasn't been well studied — check with your healthcare provider first.

In adults, Lactase is generally well tolerated; a rare case of allergic reaction (contact dermatitis and allergic rhinitis) has been reported in someone exposed to powdered lactase. Lipase is generally well tolerated in supplement form, though no serious adverse effects in adults have been formally documented.

In premature infants, a specific recombinant lipase added to formula or breast milk has caused gastrointestinal problems including abdominal pain, constipation, vomiting, and in rare cases necrotizing enterocolitis (a serious bowel condition); this product is not intended for premature infants unless under medical guidance.

Side effects, ingredient by ingredient Lactase Papain Lipase

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 3 matched ingredients can interact with medications — Papain.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

No interactions are documented in our data for the ingredients we could verify. We couldn't check Protease Blend and Amylase, so if you take medications, use the search tool below to be thorough.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a digestive enzyme blend that may help if you have trouble digesting lactose or fats. If you have serious digestive conditions or are pregnant or breastfeeding, talk with your doctor before starting — especially about Lipase.

Run your medications through the checker on this page before you begin, and let your pharmacist know if you have any concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Fat/High Lipase Digestion, straight from the product label.

Brand Theramedix BioSET
Barcode (UPC) 738676954104
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 321759
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Fat/High Lipase Digestion by Theramedix BioSET, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
738676954104
IngredientAmount% DV
Lactase0 NP--
Proprietary Enzyme Blend302 mg--
Protease Blend0 NP--
Lipase0 NP--
Amylase0 NP--

Other ingredients: Hypromellose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Fat/High Lipase Digestion aids in the proper digestion of fats, carbs, protein, and dairy, while promoting cholesterol metabolism.

Absolutely no fillers added

Professional strength formula

Fat digestion/Cholesterol metabolism

Vegetarian

Optimizing enzyme potential

Suggested/Recommended/Usage/Directions

Recommended usage: Take 1 capsule before each meal or snack.

Formula

Exclusive Thera-Blend formulation Thera-Blend is our exclusive process for formulating enzyme blends. These blends are formulated using multiple enzyme forms selected for their ability to break down numerous bonds in varying pH levels.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Keep out of reach of children

Storage

Store tightly closed in a cool, dry place.

Do not expose to excessive heat.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Fat/High Lipase Digestion by Theramedix BioSET label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Fat/High Lipase Digestion label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Fat/High Lipase Digestion by Theramedix BioSET

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Enzyme Blend

302 mg per serving

Other (inactive) ingredients: Hypromellose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Fat/High Lipase Digestion by Theramedix BioSET Drug Interactions

Want to check YOUR meds against Fat/High Lipase Digestion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Moderate

Ingredients driving the most interactions

Protease Blend 2

Individual Drug Interactions

The ingredients in Fat/High Lipase Digestion interact with 2 drugs. Click any drug to see the details.

1 of the 4 ingredients in Fat/High Lipase Digestion interact with drugs. Each result below shows which ingredient is responsible. Protease Blend

Each ingredient & the kinds of drugs it affects

For each ingredient in Fat/High Lipase Digestion with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Protease Blend1 drug type · 2 drugs

Warfarin (Coumadin)

Theoretically, papain might increase the effects and side effects of warfarin.
In one case report, a patient previously stable on warfarin was found to have an international normalization ratio (INR) of 7.4, which was attributed to ingestion of a supplement containing papain from papaya extract.

Likelihood Possible Evidence D
Protease Blend full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Fat/High Lipase Digestion, from the product label.

Theramedix BioSET

See all Theramedix BioSET products
Name
Theramedix BioSET
Street Address
2000 Highway 29 S
City
Anderson
State
SC
ZipCode
29626
Phone Number
877-246-7381
Web Address
www.theramedixbioset.com
Pharmacist Counseling Corner

Fat/High Lipase Digestion by Theramedix BioSET: Common Questions

Does Fat/High Lipase Digestion by Theramedix BioSET interact with any medications?
Yes. Based on its ingredients, Fat/High Lipase Digestion has a known interaction with 2 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Fat/High Lipase Digestion contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with my lactose intolerance?
Lactase, one of the active ingredients, is effective for lactose intolerance. The product also contains other digestive enzymes, so it may support overall digestion as well.
Is Lactase safe if I'm pregnant?
Yes — Lactase is rated likely safe in pregnancy and lactation. The other enzymes in this product haven't been well studied in pregnancy, so check with your doctor before taking it.
Can I take this if I have inflammatory bowel disease?
The evidence that Lipase and Amylase help with inflammatory bowel disease isn't established in our data. Because you have a serious digestive condition, use this only under medical guidance — talk to your doctor before starting.
What are the inactive ingredients?
The capsule contains Hypromellose and water. These are excipients that hold the active enzymes together.
Has anyone had side effects from this product?
In adults, no adverse effects have been reported. One rare case of allergic reaction to powdered Lactase (contact dermatitis and allergic rhinitis) was documented in someone with direct occupational exposure — not from taking a supplement. If you have concerns about side effects, let your pharmacist know.
Can my premature infant take this?
This product is not intended for premature infants unless under medical guidance. Specific recombinant lipase products given to premature infants have caused serious gastrointestinal problems; talk to your pediatrician about what's safe for your infant.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Fat/High Lipase Digestion is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Fat/High Lipase Digestion label
Go deeper

The Full Monographs Behind Fat/High Lipase Digestion’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactase

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...

Read the full Lactase monograph → Herb & supplement monograph

Papain

Interacts with 2 drugs

Papain is a protein-digesting enzyme from the papaya plant that is used in digestive supplements and some topical products. While it has clear food and laboratory uses, strong human evidence...

Read the full Papain monograph → Herb & supplement monograph

Lipase

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...

Read the full Lipase monograph →
Sources

Sources & How We Checked

Fat/High Lipase Digestion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Papain 11 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Saf 1997;17:342-56.
  3. Shuttleworth D, Hill S, Marks R, Connelly DM. Relief of experimentally induced pruritus with a novel eutectic mixture of local anaesthetic agents. Br J Dermatol 1988;119:535-40.
  4. Mansfield LE, Ting S, Haverly RW, Yoo TJ. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge. Ann Allergy 1985;55:541-3.
  5. Martin, T., Uhder, K., Kurek, R., Roeddiger, S., Schneider, L., Vogt, H. G., Heyd, R., and Zamboglou, N. Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial PubMed
  6. Walker-Renard, P. Update on the medicinal management of phytobezoars. Am J Gastroenterol. 1993;88(10):1663-1666.
  7. Tymoszuk D, Wiszniewska M, Walusiak-Skorupa J. Papain-induced occupational rhinoconjunctivitis and asthma - A case report. Med Pr 2016;67(1):109-12. PubMed
  8. Soto-Mera MT, López-Rico MR, Filgueira JF, et al. Occupational allergy to papain. Allergy 2000;55(10):983-4. PubMed
  9. Tarlo SM, Shaikh W, Bell B, et al. Papain-induced allergic reactions. Clin Allergy 1978;8(3):207-15. PubMed
  10. Baur X, König G, Bencze K, Fruhmann G. Clinical symptoms and results of skin test, RAST and bronchial provocation test in thirty-three papain workers: Evidence for strong immunogenic potency and clinically relevant proteolytic e?ects of airborne papain. C
  11. Novey HS, Keenan WJ, Fairshter RD, Wells ID, Wilson AF, Culver BD. Pulmonary disease in workers exposed to papain: clinico-physiological and immunological studies. Clin Allergy 1980;10(6):721-31. PubMed

See these in context on the Papain monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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