Interactions on record — worth a quick check against your medications. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

Superfood Ingredients & Drug Interactions

by FX Chocolate

Superfood label
See full label image
Bar Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Superfood against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Superfood is a dietary supplement by FX Chocolate with 6 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,138 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Muscadine Grape, Alpine Blueberry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Superfood by FX Chocolate

Ask about any prescription or over-the-counter medication and we check it for interactions with Superfood by FX Chocolate — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Superfood by FX Chocolate

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 6 active ingredients.
  • “AuroraBlue Wild Blueberry Blend” is a proprietary blend — the label gives one combined amount (200 mg) without saying how much of each component you get.

This bar has 5 active ingredients: Alaska Blueberry, Oval-leaf Blueberry, Alpine Blueberry, AuroraBlue Wild Blueberry Blend, and Vaccinium cespitosum Michx. (wild blueberry species), plus Muscadine Grape. These are whole-food superfruits — the bar also contains cacao, allulose, and cocoa butter as inactive ingredients.

Blueberries and related bilberry species are rich in anthocyanins and polyphenols. Muscadine grape adds proanthocyanidins and resveratrol.

Together they're positioned as antioxidant and cardiovascular-support ingredients, though the evidence for specific health claims varies.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: cellular protection with phytonutrients.
  • We looked for evidence on: Aging, Cardiovascular disease (CVD), Hypercholesterolemia, Hyperlipidemia, Hypertension, Metabolic syndrome — and 3 related terms.
  • The closest evidence on file: Blueberry is rated "Possibly Ineffective" for Hypertension (Natural Medicines).
  • Also on file: Black Psyllium is rated "Insufficient Reliable Evidence To Rate" for Hypertension.
  • Also on file: Bilberry is rated "Insufficient Reliable Evidence To Rate" for Atherosclerosis, Hyperlipidemia, Hypertension, Metabolic syndrome.

The evidence for what these ingredients can actually do is mixed. For blueberry, we don't have reliable evidence to rate its use for age-related thinking changes, anxiety, athletic performance, cholesterol (hyperlipidemia), or heart disease — and it appears possibly ineffective for high blood pressure.

For bilberry (Alpine Blueberry and Vaccinium cespitosum), the picture is similar: evidence is insufficient for thinking changes, eye health including age-related macular degeneration, heart disease, and cholesterol, and it's possibly ineffective for night vision. Muscadine grape appears possibly effective for chronic venous insufficiency (leg circulation problems), but possibly ineffective for nausea from chemotherapy, hay fever, and weight loss.

Overall, this bar's health claims rest on food-level consumption and traditional use rather than strong clinical trial data.

The evidence, ingredient by ingredient Black Psyllium Blueberry Bilberry Grape

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blueberry whole fruit is generally well tolerated and widely eaten as food. The main side effects from freeze-dried blueberries in studies were gastrointestinal — constipation, diarrhea, nausea, and vomiting; in one trial, 26% of participants taking 50 grams daily dropped out in the first week due to stomach complaints.

Bilberry fruit as food is safe, but concentrated bilberry supplements have limited safety research. Common side effects include dark-colored stools, flatulence, and stomach discomfort; in one study, 50% of people taking bilberry extract reported dark green stools.

Grape as whole fruit is safe; grape extracts are generally well tolerated, with occasional reports of stomach pain, diarrhea, dry mouth, headache, and joint pain. Rarely, anaphylaxis to grape skin has been reported.

For pregnancy and breastfeeding: blueberry is rated Likely Safe, but concentrated supplements have not been well studied. Bilberry is rated Likely Safe, though the safety data for high-dose extracts is limited.

Grape is rated Likely Safe, but concentrated grape supplements and wine should be avoided during pregnancy due to limited safety data. There isn't enough information on concentrated grape supplements while breastfeeding.

Talk with your doctor or pharmacist about whether this bar fits your pregnancy or breastfeeding plans.

Side effects, ingredient by ingredient Black Psyllium Blueberry Bilberry Grape

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Black Psyllium, Bilberry, Grape, Blueberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 2,139 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start this bar, double-check with your doctor or pharmacist if you take anticoagulant or antiplatelet drugs (blood thinners like warfarin, clopidogrel, or aspirin) — the bilberry and grape may increase bleeding risk. Also check if you take antidiabetes drugs (diabetes medications), erlotinib (Tarceva, a cancer drug), buspirone (BuSpar, an anxiety medication), cyclosporine (an immunosuppressant), midazolam (Versed, a sedative), or phenacetin — grape and bilberry may raise or lower their levels.

Lastly, if you take any drug that your liver clears via CYP1A2, CYP2D6, CYP3A4, or CYP2E1 enzyme systems, flag this bar with your pharmacist, because grape extracts may interfere.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This is a whole-food chocolate bar with superfruits — fine as a snack if you're looking for antioxidants and don't take blood thinners, diabetes medications, or certain other drugs. If you take any medications, especially blood thinners, diabetes drugs, cancer drugs, or anything your liver has to break down, check with your doctor or pharmacist before adding this bar to your routine.

The side effects reported in studies were mostly mild and gastrointestinal.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Superfood, straight from the product label.

Brand FX Chocolate
Net contents 15 Square(s); 2.38 Ounce(s); 67.5 Gram(s)
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 286842
Product type Botanical
Supplement form Bar
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Superfood by FX Chocolate, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4.5 Gram(s)
Maximum serving Sizes:
4.5 Gram(s)
Servings per container
15
IngredientAmount% DV
Calories15 Calorie(s)--
Total Carbohydrates3 Gram(s)1%
Added Sugars0 Gram(s)--
Total Sugars0 Gram(s)--
Total Fat1 Gram(s)1%
Saturated Fat0.5 Gram(s)3%
Dietary Fiber1 Gram(s)4%
Alaska Blueberry0 NP--
Oval-leaf Blueberry0 NP--
Alpine Blueberry0 NP--
AuroraBlue Wild Blueberry Blend200 mg--
Vaccinium cespitosum Michx.0 NP--
Muscadine Grape200 mg--

Other ingredients: Cacao, Allulose, Cocoa Butter

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Blueberry & grape phytonutrients + smooth cacao

Chocolate just got upgraded! Hand picked, AuroraBlue wild blueberries containing flavonoids support cellular protection. Mix that with muscadine grape and it ramps up the natural, beneficial nutrients found in chocolate, delivering super-power phytonutrients.

Keto

Small batch chocolate We've got chocolate down to a science.

FDA Statement of Identity

Dietary Supplement

General Statements

15 - 0.16 oz (4.5 g) squares net wt. 2.38 oz (67.5 g)

Precautions

Made on equipment shared with nuts and milk.

Report any adverse reactions to: (860) 498-2236

Suggested/Recommended/Usage/Directions

Recommended use: Take one square per day. Can take up to four squares per day as needed.

Brand IP Statement(s)

AuroraBlue is a registered trademark of Denali BioTechnologies, Inc.

Storage

Store in a cool, dry place.

Formulation

Vegan

Gluten free Non GMO

2X potency tested

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Superfood by FX Chocolate label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Superfood label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Superfood by FX Chocolate

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size4.5 Gram(s) Dosage formBar Servings per container15 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
1 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

AuroraBlue Wild Blueberry Blend

200 mg per serving

Muscadine Grape

Interacts with
910 drugs
200 mg per serving Form: Vitis rotundifolia, Vitis rotundifolia

Grapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support heart and b...

Muscadine Grape monograph & interactions

Other (inactive) ingredients: Cacao, Allulose, Cocoa Butter. These complete the product’s ingredient list but are not active constituents.

Interaction report

Superfood by FX Chocolate Drug Interactions

Want to check YOUR meds against Superfood?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,138Drugs
949 Moderate 1,189 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
Muscadine Grape 910
Alpine Blueberry 275
Alaska Blueberry 88

Individual Drug Interactions

The ingredients in Superfood interact with 2,138 drugs. Click any drug to see the details.

4 of the 6 ingredients in Superfood interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Muscadine Grape Alpine Blueberry Alaska Blueberry

Each ingredient & the kinds of drugs it affects

For each ingredient in Superfood with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Muscadine Grape9 drug types · 910 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro evidence suggests that grape extracts might decrease platelet aggregation.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

Ingesting grape juice with cyclosporine can reduce cyclosporine absorption.
A small pharmacokinetic study in healthy young adults shows that intake of purple grape juice 200 mL along with cyclosporine can decrease the absorption of cyclosporine by up to 30% when compared with water. Separate doses of grape juice and cyclosporine by at least 2 hours to avoid this interaction.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
A small pharmacokinetic study in healthy adults shows that ingestion of 200 mL of grape juice decreases phenacetin plasma levels. This is thought to be due to induction of CYP1A2.

Likelihood Possible Evidence B
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, grape seed extract may increase the levels of CYP2D6 substrates.
In vitro evidence suggests that grape seed extract might inhibit CYP2D6 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
In vitro and animal research suggests that grape seed proanthocyanidin extract inhibits CYP2E1 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
In vitro evidence suggests that grape seed extract might inhibit CYP3A4 enzymes. However, evidence from animal research shows that grape seed extract may induce CYP3A4 in the liver. So far, these interactions have not been reported in humans.

Likelihood Possible Evidence D
Midazolam (Versed)

Theoretically, long-term intake of grape seed extract might decrease the effects of midazolam.
Animal research shows that subchronic ingestions of grape seed extract can increase the elimination of intravenous midazolam by increasing hepatic CYP3A4 activity. Single doses of grape seed extract do not appear to affect midazolam elimination.

Likelihood Possible Evidence D
Phenacetin

Grape juice might decrease phenacetin absorption.
A small pharmacokinetic study in healthy adults shows that ingestion of 200 mL of grape juice decreases phenacetin plasma levels. This is thought to be due to induction of cytochrome P450 1A2 (CYP1A2).

Likelihood Possible Evidence B
Cytochrome P450 2C9 (Cyp2C9) Substrates

It is unclear if grape juice or grape seed extract inhibits CYP2C9; research is conflicting.
In vitro evidence shows that grape seed extract or grape juice might inhibit CYP2C9 enzymes. However, a small pharmacokinetic study in healthy adults shows that drinking 8 ounces of grape juice once does not affect the clearance of flurbiprofen, a probe-drug for CYP2C9 metabolism. The effects of continued grape juice consumption are unclear.

Likelihood Unlikely Evidence D
Muscadine Grape full monograph & interactions

Alpine Blueberry4 drug types · 275 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro, animal, and clinical research suggest that anthocyanidin extracts from bilberry can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that bilberry leaf extract might have blood glucose-lowering activity. Also, one small clinical trial in patients with type 2 diabetes shows that taking bilberry fruit extract 470 mg as a single dose prior to an oral glucose tolerance test lowers plasma glucose levels when compared with placebo.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Animal research shows that exposure to small concentrations of bilberry extract in drinking water for around one month increased CYP2E1 activity by 31%. However, exposure over a 2-month period did not increase CYP2E1 activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Erlotinib (Tarceva)

Theoretically, bilberry fruit extract might reduce the efficacy of erlotinib.
In vitro research suggests that bilberry fruit extract and its constituents, delphinidin and delphinidin-3-O-glucoside, inhibit the activity of erlotinib. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Alpine Blueberry full monograph & interactions

Alaska Blueberry3 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
Alaska Blueberry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Superfood, from the product label.

FX Chocolate

See all FX Chocolate products
Name
FX Chocolate
Street Address
14 Commerce Blvd.
City
Palm Coast
State
FL
ZipCode
32164
Phone Number
(860) 498-2236
Web Address
fxchocolate.com/coa
Pharmacist Counseling Corner

Superfood by FX Chocolate: Common Questions

Does Superfood by FX Chocolate interact with any medications?
Yes. Based on its ingredients, Superfood has a known interaction with 2,138 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Superfood contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Eating blueberries and grapes as whole fruit is fine, and both are rated Likely Safe in pregnancy and lactation. However, this bar is a concentrated supplement form, and the safety data for high-dose extracts isn't complete — especially for bilberry. Talk with your doctor or pharmacist about whether it's right for you during pregnancy or while breastfeeding.
Will this bar actually help my cholesterol or blood pressure?
The evidence doesn't support it. Blueberry appears possibly ineffective for high blood pressure, and we don't have reliable evidence that it lowers cholesterol. Bilberry is also rated insufficient evidence for cholesterol. While these are nutrient-rich superfruits, this bar isn't proven for those specific goals.
What are the most common side effects?
In studies, the main complaints were gastrointestinal: constipation, diarrhea, nausea, vomiting, and flatulence. Bilberry and grape can also turn your stools dark green or black, which is harmless but noticeable. In one freeze-dried blueberry study, about a quarter of people dropped out in the first week due to stomach upset.
Is it safe to eat this every day?
Blueberries as whole fruit are safe daily. Bilberry fruit and grape as whole fruit are generally safe, but long-term supplement safety data is limited. If you eat this bar regularly, watch for any stomach issues and mention it to your doctor or pharmacist at your next visit.
What's in this bar besides the berries?
The active ingredients are five blueberry/bilberry varieties and muscadine grape. The inactive ingredients are cacao, allulose (a sugar substitute), and cocoa butter — no artificial fillers or binders.
Can this help with age-related memory or thinking?
We don't have reliable evidence to say whether it can or can't. Blueberry and bilberry are both rated insufficient evidence for age-related cognitive decline. While these fruits are nutrient-rich and traditional brain-health foods, clinical trials haven't confirmed that benefit yet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Superfood label
Go deeper

The Full Monographs Behind Superfood’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Blueberry

Interacts with 88 drugs

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most people. Concentrated supplements are mark...

Read the full Blueberry monograph → Herb & supplement monograph

Bilberry

Interacts with 275 drugs

Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye health, circulation, and mild diarrhea. While...

Read the full Bilberry monograph → Herb & supplement monograph

Grape

Interacts with 910 drugs

Grapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support heart and blood vessel health. While the food is he...

Read the full Grape monograph →
Sources

Sources & How We Checked

Superfood's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 73 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
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See these in context on the Black Psyllium monograph →

Blueberry 7 references
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See these in context on the Blueberry monograph →

Bilberry 14 references
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  9. Biedermann L, Mwinyi J, Scharl M, Frei P, Zeitz J, Kullak-Ublick GA, et al. Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis-an open pilot study. 2013 May;7(4):271-9. PubMed
  10. Hoggard N, Cruickshank M, Moar KM, Bestwick C, Holst J, Russell W, et al. A single supplement of a standardized bilberry (Vaccinium myrtillus L.) extract (36% wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes control
  11. Aichinger G, Pahlke G, Nagel LJ, Berger W, Marko D. Bilberry extract, its major phenolic compounds, and soy isoflavone genistein antagonize the cytostatic drug erlotinib in human epithelial cells. Food Funct 2016;7(8):3628-36.
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See these in context on the Bilberry monograph →

Grape 34 references
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  8. Ray, S. D., Parikh, H., Hickey, E., Bagchi, M., and Bagchi, D. Differential effects of IH636 grape seed proanthocyanidin extract and a DNA repair modulator 4-aminobenzamide on liver microsomal cytochrome 4502E1-dependent aniline hydroxylation. Mol Cell B PubMed
  9. O'Byrne, D. J., Devaraj, S., Grundy, S. M., and Jialal, I. Comparison of the antioxidant effects of Concord grape juice flavonoids alpha-tocopherol on markers of oxidative stress in healthy adults. Am J Clin.Nutr. 2002;76(6):1367-1374.
  10. Schaefer, E., Peil, H., Ambrosetti, L., and Petrini, O. Oedema protective properties of the red vine leaf extract AS 195 (Folia vitis viniferae) in the treatment of chronic venous insufficiency. A 6-week observational clinical trial. Arzneimittelforschun PubMed
  11. Nishikawa, M., Ariyoshi, N., Kotani, A., Ishii, I., Nakamura, H., Nakasa, H., Ida, M., Nakamura, H., Kimura, N., Kimura, M., Hasegawa, A., Kusu, F., Ohmori, S., Nakazawa, K., and Kitada, M. Effects of continuous ingestion of green tea or grape seed extra
  12. de Lange, D. W., Scholman, W. L., Kraaijenhagen, R. J., Akkerman, J. W., and van de Wiel, A. Alcohol and polyphenolic grape extract inhibit platelet adhesion in flowing blood. Eur.J Clin.Invest 2004;34(12):818-824. PubMed
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  15. de Lange, D. W., Verhoef, S., Gorter, G., Kraaijenhagen, R. J., van de Wiel, A., and Akkerman, J. W. Polyphenolic grape extract inhibits platelet activation through PECAM-1: an explanation for the French paradox. Alcohol Clin.Exp.Res 2007;31(8):1308-1314 PubMed
  16. Etheridge, A. S., Black, S. R., Patel, P. R., So, J., and Mathews, J. M. An in vitro evaluation of cytochrome P450 inhibition and P-glycoprotein interaction with goldenseal, Ginkgo biloba, grape seed, milk thistle, and ginseng extracts and their constitu
  17. Krikorian, R., Nash, T. A., Shidler, M. D., Shukitt-Hale, B., and Joseph, J. A. Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment. Br J Nutr. 2010;103(5):730-734. PubMed
  18. Ingersoll, G. L., Wasilewski, A., Haller, M., Pandya, K., Bennett, J., He, H., Hoffmire, C., and Berry, C. Effect of concord grape juice on chemotherapy-induced nausea and vomiting: results of a pilot study. Oncol.Nurs.Forum 2010;37(2):213-221. PubMed
  19. Oliveira-Freitas, V. L., Dalla, Costa T., Manfro, R. C., Cruz, L. B., and Schwartsmann, G. Influence of purple grape juice in cyclosporine bioavailability. J Ren Nutr. 2010;20(5):309-313. PubMed
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  22. Rabe, E., Stucker, M., Esperester, A., Schafer, E., and Ottillinger, B. Efficacy and tolerability of a red-vine-leaf extract in patients suffering from chronic venous insufficiency--results of a double-blind placebo-controlled study. Eur.J Vasc.Endovasc. PubMed
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  30. Brito, FF., Martinez, A., Palacios, R., Mur, P., Gomez, E., Galindo, P. A., Borja, J., and Martinez, J. Rhinoconjunctivitis and asthma caused by vine pollen: a case report. J Allergy Clin Immunol 1999;103(2 Pt 1):262-266. PubMed
  31. Ras RT, Zock PL, Zebregs YE, et al. Effect of polyphenol-rich grape seed extract on ambulatory blood pressure in subjects with pre- and stage I hypertension. Br J Nutr 2013;110(12):2234-41. PubMed
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  33. Martínez-Maqueda D, Zapatera B, Gallego-Narbón A, Vaquero MP, Saura-Calixto F, Pérez-Jiménez J. A 6-week supplementation with grape pomace to subjects at cardiometabolic risk ameliorates insulin sensitivity, without affecting other metabolic syndrome mark
  34. Moon SW, Shin YU, Cho H, Bae SH, Kim HK; and for the Mogen Study Group. Effect of grape seed proanthocyanidin extract on hard exudates in patients with non-proliferative diabetic retinopathy. Medicine (Baltimore) 2019;98(21):e15515. PubMed

See these in context on the Grape monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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