SuperImmune+ Ingredients & Drug Interactions
What is this page for?
First and foremost: checking SuperImmune+ against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
SuperImmune+ is a dietary supplement by Quantum Health with 3 active ingredients. Its ingredients are commonly taken for cold sores (herpes labialis), genital herpes outbreaks, supporting protein and collagen formation.Based on those ingredients, 209 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astragalus Root Extract, L-Lysine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against SuperImmune+ by Quantum Health
Ask about any prescription or over-the-counter medication and we check it for interactions with SuperImmune+ by Quantum Health — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of SuperImmune+ by Quantum Health
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
SuperImmune+ contains three active ingredients. L-Lysine is an amino acid studied most for cold sores (herpes labialis), where evidence suggests it may help.
Olive Leaf Extract is a concentrated form of compounds from the olive plant; the evidence for its health effects isn't well established yet. Astragalus Root Extract is derived from the astragalus plant and is traditionally used for immune support, though rigorous evidence for its specific benefits is limited.
The capsule also contains inactive ingredients—hypromellose, microcrystalline cellulose, magnesium stearate, and water—which are common binders and fillers that help form and preserve the capsule.
Does it work?
Not established
L-Lysine is possibly effective for cold sores (herpes labialis). For other uses listed—child growth, pressure ulcers, and diabetic foot ulcers—we don't have enough reliable evidence to rate how well it works.
For Olive Leaf Extract and Astragalus Root Extract, the evidence isn't established in the data we hold. Both are listed with multiple health claims—hay fever, asthma, angina, and others for astragalus—but all are rated insufficient reliable evidence.
That doesn't mean they don't work; it means the science isn't solid enough yet for us to say one way or the other.
How safe is it?
Well-documented data
L-Lysine is generally well tolerated at typical doses, though high amounts may cause stomach upset, diarrhea, or indigestion. Long-term safety hasn't been well studied.
One rare case report linked oral lysine to a kidney condition, but this is not common. Olive Leaf Extract is generally well tolerated; the most common side effects in trials were headache and stomach discomfort.
One person reported skin problems. Astragalus is generally well tolerated short-term in healthy adults, though human safety data is limited.
Reported effects include dizziness and, rarely, temporary heart palpitations, though these may not have been caused by astragalus itself. Pregnant or breastfeeding individuals should avoid astragalus—there isn't enough safety data.
For L-Lysine and Olive Leaf Extract during pregnancy and breastfeeding, the data isn't on file; talk with your doctor or pharmacist for personalized advice.
Meds to double-check
Moderate interaction found
Check your medications if you take immunosuppressants (including those used after organ transplant), lithium, cyclophosphamide (chemotherapy), or diabetes drugs—all carry Moderate-severity interactions with astragalus. Also check if you take 5-HT4 agonists (a Minor interaction with L-Lysine).
Use the interaction checker below with your full medication list.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
SuperImmune+ may help with cold sores if L-Lysine is your main reason for taking it. If you take immunosuppressants, lithium, diabetes medications, or 5-HT4 agonists, check your exact medications with the tool on this page before starting.
Pregnant or breastfeeding individuals should avoid the astragalus in this product. Talk to your pharmacist if you're unsure whether it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about SuperImmune+, straight from the product label.
| Brand | Quantum Health |
|---|---|
| Barcode (UPC) | 046985001120 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Dec 14, 2023 |
| DSLD ID | 299886 |
| Product type | Botanical With Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for SuperImmune+ by Quantum Health, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Lysine | 1.5 Gram(s) | -- |
| Olive Leaf Extract | 100 mg | -- |
| Astragalus Root Extract | 200 mg | -- |
Other ingredients: Hypromellose, Water, Microcrystalline Cellulose, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: Take 3 capsules daily.
Precautions
Warning: Keep out of reach of children.
If pregnant or breastfeeding or if you have a medical condition or if taking any medications or other supplements, consult a health professional before use.
Safety sealed for your protection
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
Vegetarian Power Formula
Vegetarian Power Formula
Formula
Lysine, Olive leaf, & Astragalus
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
SuperImmune+ by Quantum Health label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in SuperImmune+ by Quantum Health
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Lysine
Interacts with1 drug
Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...
L-Lysine monograph & interactionsOlive Leaf Extract
No knowninteractions
Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...
Olive Leaf Extract monograph & interactionsAstragalus Root Extract
Interacts with208 drugs
Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While...
Astragalus Root Extract monograph & interactionsOther (inactive) ingredients: Hypromellose, Water, Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
SuperImmune+ by Quantum Health Drug Interactions
HelloPharmacist Interaction Report
SuperImmune+ by Quantum Health contains three active ingredients, and two of them have documented interactions with medications.
The most serious concerns involve Astragalus Root Extract, which carries Moderate-severity interactions with several drug types.
Read the full breakdown — every affected drug type, severity by severity
Astragalus may interfere with immunosuppressants (drugs that weaken your immune system on purpose, often used after transplants or for autoimmune conditions) and cyclophosphamide, a chemotherapy agent. It may also increase lithium levels, which could lead to toxicity—astragalus appears to have mild diuretic properties that could reduce how your body clears lithium.
Additionally, astragalus might raise the risk of low blood sugar (hypoglycemia) if you're taking diabetes medications, since it seems to lower blood sugar on its own.
L-Lysine carries a Minor interaction with 5-HT4 agonists (a class of drugs used for certain bowel conditions), theoretically reducing their effects. Olive Leaf Extract has no known interactions documented in our data.
Altogether, these interactions span 204 individual medications. If you take any prescription medication—especially immunosuppressants, lithium, diabetes drugs, or 5-HT4 agonists—run it through the interaction checker on this page before you start SuperImmune+.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against SuperImmune+?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in SuperImmune+ interact with 209 drugs. Click any drug to see the details.
2 of the 3 ingredients in SuperImmune+ interact with drugs. Each result below shows which ingredient is responsible. Astragalus Root Extract L-Lysine
Betamethasone ValerateLuxiq
How Betamethasone Valerate interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Betamethasone Valerate interactionBimekizumab-bkzxBimzelx
How Bimekizumab-bkzx interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Bimekizumab-bkzx interactionCanagliflozinInvokana
How Canagliflozin interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Canagliflozin interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Canagliflozin, Metformin Hydrochloride interactionChlorpropamideChlorpropam, Diabinese
How Chlorpropamide interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Chlorpropamide interactionCiclesonideAlvesco, Omnaris, Zetonna
How Ciclesonide interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Ciclesonide interactionCisplatinPlatinol-AQ
How Cisplatin interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Cisplatin interactionCladribineLeustatin, Mavenclad
How Cladribine interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Cladribine interactionCopanlisibAliqopa
How Copanlisib interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Copanlisib interactionCortisone AcetateCortisone Tablets, Cortone
How Cortisone Acetate interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Cortisone Acetate interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants, Cyclophosphamide Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Cyclophosphamide interactionCyclosporineCequa, Ciclosporine, Gengraf, Neoral, Sandimmune, Verkazia +1 more
How Cyclosporine interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Cyclosporine interactionDaclizumabZenapax, Zinbryta
How Daclizumab interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Daclizumab interactionDapagliflozinFarxiga
How Dapagliflozin interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Dapagliflozin interactionDapagliflozin Propanediol, MetforminXigduo XR
How Dapagliflozin Propanediol, Metformin interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Dapagliflozin Propanediol, Metformin interactionDapagliflozin Propanediol, Saxagliptin HydrochlorideQtern
How Dapagliflozin Propanediol, Saxagliptin Hydrochloride interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interactionDapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
How Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionDasiglucagon HydrochlorideZegalogue
How Dasiglucagon Hydrochloride interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Dasiglucagon Hydrochloride interactionDeflazacortEmflaza
How Deflazacort interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Deflazacort interactionDenosumabProlia, XGEVA
How Denosumab interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Denosumab interactionDeucravacitinibSotyktu
How Deucravacitinib interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Deucravacitinib interactionDexamethasoneDecadron, Dexone, Dextenza, Dexycu, Hemady, Hexadrol +1 more
How Dexamethasone interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Dexamethasone interactionDiroximel FumarateVumerity
How Diroximel Fumarate interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Diroximel Fumarate interactionDulaglutideTrulicity
How Dulaglutide interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Dulaglutide interactionDurvalumabImfinzi
How Durvalumab interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Durvalumab interactionEculizumabSoliris
How Eculizumab interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Eculizumab interactionEfalizumabRaptiva
How Efalizumab interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Efalizumab interactionEfgartigimod Alfa-fcabVyvgart
How Efgartigimod Alfa-fcab interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Efgartigimod Alfa-fcab interactionElranatamabElrexfio
How Elranatamab interacts with SuperImmune+ — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Elranatamab interactionEach ingredient & the kinds of drugs it affects
For each ingredient in SuperImmune+ with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Astragalus Root Extract
Antidiabetes Drugs
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.
Cyclophosphamide
Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.
Immunosuppressants
Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.
Lithium
Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.
L-Lysine
5-Ht4 Agonists
Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.
Brand information
Manufacturer and brand details for SuperImmune+, from the product label.
Quantum Health
See all Quantum Health products- Name
- Quantum, Inc.
- Street Address
- PO Box 2791
- City
- Eugene
- State
- OR
- ZipCode
- 97402
- Phone Number
- 800-448-1448
- Web Address
- www.quantumhealth.com
SuperImmune+ by Quantum Health: Common Questions
Does SuperImmune+ by Quantum Health interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does L-Lysine really help with cold sores?
Can I take this if I'm pregnant or breastfeeding?
What are the most common side effects?
Is this safe to take long-term?
What does astragalus do in this product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if SuperImmune+ is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind SuperImmune+’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lysine
Interacts with 1 drugLysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to try to prevent or shorten cold sores, but...
Read the full Lysine monograph → Herb & supplement monographOlive
Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyrosol. Olive oil as part of a Mediterrane...
Read the full Olive monograph → Herb & supplement monographAstragalus
Interacts with 208 drugsAstragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...
Read the full Astragalus monograph →Sources & How We Checked
SuperImmune+'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 22 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lysine 7 references
- Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol 1984;58:659-66. PubMed
- McCune MA, Perry HO, Muller SA, O'Fallon WM. Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis 1984;34:366-73.
- DiGiovanna JJ, Blank H. Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Arch Dermatol 1984;120:48-51. DOI
- Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
- Griffith RS, Walsh DE, Myrmel KH, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Dermatologica 1987;175:183-90. DOI
- Lo JC, Chertow GM, Rennke H, Seifter JL. Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion. Am J Kidney Dis 1996;28:614-7. PubMed
- Smriga M, Torii K. L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15370-5.
Olive 2 references
- Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
- Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed
Astragalus 13 references
- Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
- Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
- Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
- Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
- Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
- Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
- Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
- Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
- Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
- Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
- Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
- Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
- Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC