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Dietary supplement

SuperImmune+ Ingredients & Drug Interactions

by Quantum Health

Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

SuperImmune+ is a dietary supplement by Quantum Health with 3 active ingredients. Its ingredients are commonly taken for cold sores (herpes labialis), genital herpes outbreaks, supporting protein and collagen formation.Based on those ingredients, 209 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astragalus Root Extract, L-Lysine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of SuperImmune+ by Quantum Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

SuperImmune+ contains three active ingredients. L-Lysine is an amino acid studied most for cold sores (herpes labialis), where evidence suggests it may help.

Olive Leaf Extract is a concentrated form of compounds from the olive plant; the evidence for its health effects isn't well established yet. Astragalus Root Extract is derived from the astragalus plant and is traditionally used for immune support, though rigorous evidence for its specific benefits is limited.

The capsule also contains inactive ingredients—hypromellose, microcrystalline cellulose, magnesium stearate, and water—which are common binders and fillers that help form and preserve the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: immune support and general wellness.
  • We looked for evidence on: Exercise-induced respiratory infections, Influenza, Upper respiratory tract infection (URTI), Common cold, Respiratory health, Immune function.
  • The closest evidence on file: Olive is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced respiratory infections (Natural Medicines).
  • Also on file: Olive is rated "Insufficient Reliable Evidence To Rate" for Influenza.
  • Also on file: Astragalus is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI).

L-Lysine is possibly effective for cold sores (herpes labialis). For other uses listed—child growth, pressure ulcers, and diabetic foot ulcers—we don't have enough reliable evidence to rate how well it works.

For Olive Leaf Extract and Astragalus Root Extract, the evidence isn't established in the data we hold. Both are listed with multiple health claims—hay fever, asthma, angina, and others for astragalus—but all are rated insufficient reliable evidence.

That doesn't mean they don't work; it means the science isn't solid enough yet for us to say one way or the other.

The evidence, ingredient by ingredient Lysine Olive Astragalus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Lysine is generally well tolerated at typical doses, though high amounts may cause stomach upset, diarrhea, or indigestion. Long-term safety hasn't been well studied.

One rare case report linked oral lysine to a kidney condition, but this is not common. Olive Leaf Extract is generally well tolerated; the most common side effects in trials were headache and stomach discomfort.

One person reported skin problems. Astragalus is generally well tolerated short-term in healthy adults, though human safety data is limited.

Reported effects include dizziness and, rarely, temporary heart palpitations, though these may not have been caused by astragalus itself. Pregnant or breastfeeding individuals should avoid astragalus—there isn't enough safety data.

For L-Lysine and Olive Leaf Extract during pregnancy and breastfeeding, the data isn't on file; talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Lysine Olive Astragalus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Lysine, Astragalus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 209 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take immunosuppressants (including those used after organ transplant), lithium, cyclophosphamide (chemotherapy), or diabetes drugs—all carry Moderate-severity interactions with astragalus. Also check if you take 5-HT4 agonists (a Minor interaction with L-Lysine).

Use the interaction checker below with your full medication list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

SuperImmune+ may help with cold sores if L-Lysine is your main reason for taking it. If you take immunosuppressants, lithium, diabetes medications, or 5-HT4 agonists, check your exact medications with the tool on this page before starting.

Pregnant or breastfeeding individuals should avoid the astragalus in this product. Talk to your pharmacist if you're unsure whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about SuperImmune+, straight from the product label.

Brand Quantum Health
Barcode (UPC) 046985001120
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 299886
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for SuperImmune+ by Quantum Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
046985001120
IngredientAmount% DV
L-Lysine1.5 Gram(s)--
Olive Leaf Extract100 mg--
Astragalus Root Extract200 mg--

Other ingredients: Hypromellose, Water, Microcrystalline Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take 3 capsules daily.

Precautions

Warning: Keep out of reach of children.

If pregnant or breastfeeding or if you have a medical condition or if taking any medications or other supplements, consult a health professional before use.

Safety sealed for your protection

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Vegetarian Power Formula

Vegetarian Power Formula

Formula

Lysine, Olive leaf, & Astragalus

FDA Statement of Identity

Dietary Supplement

See for yourself

SuperImmune+ by Quantum Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in SuperImmune+ by Quantum Health

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Lysine

Interacts with
1 drug
1.5 Gram(s) per serving Form: L-Lysine Hydrochloride

Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...

L-Lysine monograph & interactions

Olive Leaf Extract

No known
interactions
100 mg per serving

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...

Olive Leaf Extract monograph & interactions

Astragalus Root Extract

Interacts with
208 drugs
200 mg per serving Form: Astragalus membranaceus Root Extract

Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While...

Astragalus Root Extract monograph & interactions

Other (inactive) ingredients: Hypromellose, Water, Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

SuperImmune+ by Quantum Health Drug Interactions

Want to check YOUR meds against SuperImmune+?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
209Drugs
208 Moderate 1 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in SuperImmune+ with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Astragalus Root Extract4 drug types · 208 drugs

Antidiabetes Drugs

Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.

Likelihood Probable Evidence A
Cyclophosphamide

Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D

L-Lysine1 drug type · 1 drug

5-Ht4 Agonists

Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for SuperImmune+, from the product label.

Quantum Health

See all Quantum Health products
Name
Quantum, Inc.
Street Address
PO Box 2791
City
Eugene
State
OR
ZipCode
97402
Phone Number
800-448-1448
Web Address
www.quantumhealth.com
Pharmacist Counseling Corner

SuperImmune+ by Quantum Health: Common Questions

Does SuperImmune+ by Quantum Health interact with any medications?
Yes. Based on its ingredients, SuperImmune+ has a known interaction with 209 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
SuperImmune+ contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does L-Lysine really help with cold sores?
The evidence suggests it may help with cold sores (herpes labialis)—that's the one use where we rate it possibly effective. For other conditions like wound healing or growth, we don't have enough reliable evidence yet.
Can I take this if I'm pregnant or breastfeeding?
You should avoid the astragalus in this product during pregnancy and breastfeeding—there isn't enough safety data. For L-Lysine and Olive Leaf Extract, we don't have pregnancy/breastfeeding safety information on file, so talk with your doctor or pharmacist for personalized advice.
What are the most common side effects?
L-Lysine may cause stomach upset, diarrhea, or indigestion at high doses. Olive Leaf Extract may cause headache or stomach discomfort. Astragalus is generally well tolerated, though dizziness has been reported rarely.
Is this safe to take long-term?
Long-term safety data for L-Lysine and astragalus is limited. Olive Leaf Extract seems well tolerated, but concentrated supplements are less studied than whole food. Talk with your pharmacist about how long you plan to take it.
What does astragalus do in this product?
Astragalus Root Extract is included for immune support, though the evidence for specific health benefits isn't well established yet. It's been used traditionally, but rigorous science is still catching up.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if SuperImmune+ is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

SuperImmune+ label
Sources

Sources & How We Checked

SuperImmune+'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lysine 7 references
  1. Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol 1984;58:659-66. PubMed
  2. McCune MA, Perry HO, Muller SA, O'Fallon WM. Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis 1984;34:366-73.
  3. DiGiovanna JJ, Blank H. Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Arch Dermatol 1984;120:48-51. DOI
  4. Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
  5. Griffith RS, Walsh DE, Myrmel KH, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Dermatologica 1987;175:183-90. DOI
  6. Lo JC, Chertow GM, Rennke H, Seifter JL. Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion. Am J Kidney Dis 1996;28:614-7. PubMed
  7. Smriga M, Torii K. L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15370-5.

See these in context on the Lysine monograph →

Olive 2 references
  1. Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
  2. Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed

See these in context on the Olive monograph →

Astragalus 13 references
  1. Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
  2. Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
  3. Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
  4. Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
  5. Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
  6. Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
  7. Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
  8. Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
  9. Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
  10. Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
  11. Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
  12. Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
  13. Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):

See these in context on the Astragalus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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