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Dietary supplement

SuperPure Astaxanthin Ingredients & Drug Interactions

by Pure Synergy

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

SuperPure Astaxanthin is a dietary supplement by Pure Synergy with 2 active ingredients. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic, SuperPure Astaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of SuperPure Astaxanthin by Pure Synergy

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “organic, SuperPure Astaxanthin” is listed as a grouped ingredient — the label gives one combined amount (6 mg) without saying how much of each component you get.
  • “organic, SuperPure Phospholipids” is listed as a grouped ingredient — the label gives one combined amount (30 mg) without saying how much of each component you get.

This product contains two active ingredients in a blend designed to deliver astaxanthin with enhanced absorption. The astaxanthin comes from certified organic Haematococcus pluvialis algae — a microalga rich in this carotenoid antioxidant — and is paired with organic phospholipids to help your body take it up more effectively.

The formula also includes sunflower lecithin, an organic emulsifier (a substance that helps mix ingredients). The capsule itself is vegetarian, and you'll find a touch of organic grape in the formula as well.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lecithin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Ultimate antioxidant support.
  • We looked for evidence on: Age-related macular degeneration (AMD), Aging skin, Exercise-induced muscle damage, Exercise-induced muscle soreness, Heart failure, Hyperlipidemia — and 4 related terms.
  • The closest evidence on file: Lecithin is rated "Insufficient Reliable Evidence To Rate" for Hyperlipidemia (Natural Medicines).

Our data doesn't establish whether this astaxanthin product works for any particular health goal — no effectiveness ratings are listed for astaxanthin itself in the facts we hold. Sunflower lecithin, which makes up part of the formula, has been studied for several uses; the evidence shows it's likely ineffective for Alzheimer disease, while for age-related cognitive decline, anxiety, bipolar disorder, and liver fat buildup from IV nutrition, there isn't enough reliable evidence to know either way.

If you're considering this product for a specific reason, talk with us about what the broader research shows.

The evidence, ingredient by ingredient Astaxanthin Lecithin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sunflower lecithin, the ingredient we have the most safety data on, is generally well tolerated. The most common side effects people report are abdominal pain, diarrhea, a feeling of fullness, and nausea — though these are not frequent.

If you have an egg or soy allergy, know that lecithin can trigger allergic skin reactions in sensitive people. The product is rated likely safe in pregnancy and lactation.

We don't hold safety data on the Haematococcus pluvialis algae, so if you're pregnant, nursing, or have a known algae allergy, check with your doctor or pharmacist before starting.

Side effects, ingredient by ingredient Astaxanthin Lecithin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check in this product. That said, always confirm your exact medications in the interaction tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

If you're after an astaxanthin supplement without documented drug interactions, this one fits the bill — and the sunflower lecithin may help your body absorb it. Anyone taking prescription medications should still run them through the checker here just to be thorough.

If you're pregnant, nursing, or have any algae sensitivities, talk with your pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about SuperPure Astaxanthin, straight from the product label.

Brand Pure Synergy
Barcode (UPC) 852971004781
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 246681
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for SuperPure Astaxanthin by Pure Synergy, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
852971004781
IngredientAmount% DV
organic, SuperPure Astaxanthin6 mg--
certified organic Haematococcus pluvialis Algae150 mg--
organic, SuperPure Phospholipids30 mg--
certified organic Sunflower lecithin50 mg--

Other ingredients: certified organic Grape, Vegetarian Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Ultimate Antioxidant

Oregon Tilth Certified Organic (OTCO)

Non GMO

No GMO's, dairy or gluten

Formula

Our SuperPure Astaxanthin raises one of the strongest natural antioxidants on the planet to the peak of purity with our exclusive formula made with organic algae. With its organic phospholipids, it optimizes absorption for the ultimate in skin and eye health, brain and cardiovascular support optimal athletic performance and much more.

Made with organic algae

Verified Natural Algae Astaxanthin NAXA

SuperPure

Suggested/Recommended/Usage/Directions

Suggested Use: 1 capsule once or twice daily preferably with food for best absoprtion.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Oregon Tilth Certified Organic (OTCO)

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

The NAXA verified seal is a registered trademark of the Natural Algae Astaxanthin Association

See for yourself

SuperPure Astaxanthin by Pure Synergy label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in SuperPure Astaxanthin by Pure Synergy

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Organic, SuperPure Astaxanthin

Interacts with
671 drugs
6 mg per serving

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Organic, SuperPure Astaxanthin monograph & interactions
  • › Certified organic Haematococcus pluvialis Algae

Organic, SuperPure Phospholipids

30 mg per serving

Other (inactive) ingredients: Certified organic Grape, Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

SuperPure Astaxanthin by Pure Synergy Drug Interactions

Want to check YOUR meds against SuperPure Astaxanthin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in SuperPure Astaxanthin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic, SuperPure Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for SuperPure Astaxanthin, from the product label.

Pure Synergy

See all Pure Synergy products
Name
The Synergy Company
City
Moab
State
Utah
ZipCode
84532
Phone Number
800-723-0277
Web Address
thesynergycompany.com
Pharmacist Counseling Corner

SuperPure Astaxanthin by Pure Synergy: Common Questions

Does SuperPure Astaxanthin by Pure Synergy interact with any medications?
Yes. Based on its ingredients, SuperPure Astaxanthin has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
SuperPure Astaxanthin contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this give me stomach upset?
Sunflower lecithin is well tolerated overall, but some people do report abdominal pain, diarrhea, bloating, or nausea — they're not common, but they can happen. If you're prone to stomach sensitivities, start with a lower dose or take it with food.
Is it safe if I'm allergic to eggs or soy?
Lecithin can cause allergic skin reactions in people with egg or soy allergies, so if either is a concern for you, talk with us before taking this product.
Can I take this while pregnant or breastfeeding?
Sunflower lecithin is rated likely safe in pregnancy and lactation. We don't have safety data on the algae source of the astaxanthin, though, so check with your doctor or pharmacist for personalized advice before starting.
What's the Haematococcus pluvialis algae in here?
It's a freshwater microalga that's naturally rich in astaxanthin, a potent antioxidant. It's the source of the astaxanthin in this formula.
What does the lecithin do?
Sunflower lecithin acts as an emulsifier — it helps the oil-based components mix together and may improve how well your body absorbs the astaxanthin.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if SuperPure Astaxanthin is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

SuperPure Astaxanthin label
Sources

Sources & How We Checked

SuperPure Astaxanthin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Lecithin 9 references
  1. Buchman AL, Dubin M, Jenden D, et al. Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients. Gastroenterology 1992;102:1363-70.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Chatellier G, Lacomblez L. Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Francais d'Etude de la Tetrahydroaminoacridine. BMJ 1990;300:495-9.
  4. Gelenberg AJ, Dorer DJ, Wojcik JD, et al. A crossover study of lecithin treatment of tardive dyskinesia. J Clin Psychiatry 1990;51:149-53.
  5. Little A, Levy R, Chuaqui-Kidd P, Hand D. A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease. J Neurol Neurosurg Psychiatry 1985;48:736-42. PubMed
  6. Palm M, Moneret-Vautrin DA, Kanny G, et al. Food allergy to egg and soy lecithins. Allergy 1999;54:1116-7. PubMed
  7. Drachman DA, Glosser G, Fleming P, et al. Memory decline in the aged: treatment with lecithin and physostigmine. Neurology 1982;32:944-50. PubMed
  8. Gelenberg, A. J., Doller-Wojcik, J. C., and Growdon, J. H. Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study. Am J Psychiatry 1979;136(6):772-776. PubMed
  9. Electronic Code of Federal Regulations. Title 21, Chapter 1, Subchapter B, Part 184: Direct food substances affirmed as Generally Recognized as Safe. Subpart B - listing of specific substances affirmed as GRAS. Sec. 184.1400 Lecithin. Available at: https:

See these in context on the Lecithin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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