No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

SynovoDerma Ingredients & Drug Interactions

by Allergy Research Group

Softgel Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

SynovoDerma is a dietary supplement by Allergy Research Group with 1 active ingredient. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of SynovoDerma by Allergy Research Group

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

SynovoDerma contains one active ingredient: hyaluronic acid powder. Hyaluronic acid is a compound your body naturally makes—it's found in connective tissues and helps hold water, which supports skin hydration and joint function.

This softgel also includes rice bran oil, gelatin, glycerin, purified water, yellow beeswax, and titanium dioxide as inactive ingredients that help deliver and preserve the product.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: skin hydration and joint comfort support.
  • We looked for evidence on: Aging skin, Dry eye, Osteoarthritis, Wound healing, Gingivitis, Oral mucositis — and 4 related terms.
  • The strongest evidence on file: Hyaluronic Acid is rated "Possibly Effective" for Dry eye (Natural Medicines).
  • Also on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Gingivitis, Oral mucositis, Osteoarthritis, and more.

Hyaluronic acid is possibly effective for dry eye and venous leg ulcers (slow-healing wounds in the legs). For aging skin, hay fever, and sexual dysfunction, the evidence available isn't reliable enough to rate it one way or the other—we simply don't have enough solid data to say whether it works for those uses.

The evidence, ingredient by ingredient Hyaluronic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally and topically, hyaluronic acid is generally well tolerated by most adults. When applied to skin, some people have reported eczema, redness, itching, or in rare cases wound bleeding or infection.

Ocular pain has been reported rarely in patients using eye drops containing hyaluronic acid. Because long-term safety of oral hyaluronic acid supplements hasn't been fully studied, the available safety data suggests caution—talk with your doctor before starting if you're considering this for an ongoing condition.

Side effects, ingredient by ingredient Hyaluronic Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check in SynovoDerma. That said, it's always smart to confirm your specific medications with your pharmacist before adding any supplement.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you're interested in hyaluronic acid for dry eye or venous leg ulcers, this may be worth discussing with your pharmacist or doctor. The ingredient is generally well tolerated, but long-term safety isn't fully established.

Check with your healthcare provider to make sure it fits your health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about SynovoDerma, straight from the product label.

Brand Allergy Research Group
Barcode (UPC) 713947747401
Net contents 150 Softgel(s)
Market status On market
Date entered into DSLD Aug 23, 2020
DSLD ID 233441
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for SynovoDerma by Allergy Research Group, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Softgel(s)
Maximum serving Sizes:
3 Softgel(s)
Servings per container
50
UPC/BARCODE
713947747401
IngredientAmount% DV
Hyaluronic Acid powder210 mg--

Other ingredients: Rice Bran Oil, Gelatin, Glycerin, purified Water, yellow Beeswax, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

A patented hyaluronic acid (HA) formula, prepared using a proprietary enzymatic process to reduce the molecular weight to between 50-200 Kilodaltons. HA is extracted from cockscomb.

Patented Hyaluronic Acid

Suggested/Recommended/Usage/Directions

Suggested Use As a dietary supplement, 6 softgels daily for 20 days, then reduce dosage to 3 softgels daily, or as directed by a healthcare practitioner. May be taken with or without food.

Storage

Keep in a cool, dry place, tightly capped.

FDA Statement of Identity

Dietary Supplement

Formulation

Hypoallergenic

See for yourself

SynovoDerma by Allergy Research Group label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in SynovoDerma by Allergy Research Group

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Softgel(s) Dosage formSoftgel Capsule Servings per container50 Amounts shown are per serving.

Hyaluronic Acid powder

No known
interactions
210 mg per serving Form: Hyaluronic Acid

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...

Hyaluronic Acid powder monograph & interactions

Other (inactive) ingredients: Rice Bran Oil, Gelatin, Glycerin, Purified Water, Yellow Beeswax, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

SynovoDerma by Allergy Research Group Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in SynovoDerma. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for SynovoDerma, from the product label.

Allergy Research Group

See all Allergy Research Group products
Name
Allergy Research Group
City
South Salt Lake
State
UT
ZipCode
84115
Phone Number
800.545.9960
Web Address
www.allergyresearchgroup.com
Pharmacist Counseling Corner

SynovoDerma by Allergy Research Group: Common Questions

Does SynovoDerma by Allergy Research Group interact with any medications?
We do not currently list a known interaction for the mapped ingredients in SynovoDerma. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
SynovoDerma contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is hyaluronic acid, and what does it do in this product?
Hyaluronic acid is a naturally occurring compound in your body that acts like a sponge—it holds water and keeps tissues hydrated. In this supplement, it's meant to support skin moisture and joint health.
Does SynovoDerma actually work?
For dry eye and venous leg ulcers, hyaluronic acid is possibly effective based on available evidence. For aging skin, hay fever, and sexual dysfunction, we don't have enough reliable data to say whether it works.
Can I take this if I have sensitive skin?
Hyaluronic acid is generally well tolerated, but topical application has been reported to cause eczema, redness, and itching in some people. This is an oral supplement, so topical side effects are less likely—but if you have very sensitive skin, mention it to your pharmacist or doctor first.
Are there any side effects I should know about?
Taken by mouth, hyaluronic acid appears well tolerated with minimal reported side effects. Eye drops containing hyaluronic acid have rarely caused ocular pain, though this product is an oral softgel, not an eye drop.
Is this safe to take long-term?
Hyaluronic acid is generally well tolerated for most adults. However, long-term safety of oral supplements hasn't been fully studied, so talk with your doctor before taking it regularly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if SynovoDerma is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

SynovoDerma label
Go deeper

The Full Monographs Behind SynovoDerma’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

SynovoDerma's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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