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Dietary supplement

Tangerine Fruit Ingredients & Drug Interactions

by TerraVita Premium Collection

Powder Category: Botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Tangerine Fruit is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for source of vitamin c, digestive support, aromatherapy and relaxation.Based on those ingredients, 643 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Tangerine, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Tangerine Fruit by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

TerraVita Premium Collection Tangerine Fruit Powder contains one active ingredient: tangerine powder. That's it—no other active ingredients are listed.

There are no inactive fillers or other ingredients to report.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Tangerine product and its label doesn't state a use — see Tangerine's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The effectiveness data we hold for tangerine fruit rates it as having insufficient reliable evidence for cancer prevention—meaning the evidence isn't strong enough to say whether it works for that purpose. We don't have effectiveness ratings for other uses on file for this product.

The evidence, ingredient by ingredient Tangerine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tangerine fruit is generally well tolerated when you eat it as food. The safety data does flag a caution: while the fruit itself is fine, concentrated extracts and essential oils of tangerine should be used only with caution and under medical advice, since safety of those concentrated forms hasn't been thoroughly studied.

Very few adverse effects have been reported from eating tangerine, though a complete safety review hasn't been done. One case report linked tangerine essential oil in fragrance to contact dermatitis (a skin reaction), but that's a specific topical exposure, not something you'd expect from eating tangerine powder.

Pregnancy and lactation safety data isn't on file for tangerine, so there's not enough information to know either way. Talk with your doctor or pharmacist if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Tangerine

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Tangerine.
  • The most serious interaction on file is rated Minor.
  • For scale: 644 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking TerraVita Premium Collection Tangerine Fruit Powder, double-check if you take midazolam (Versed) or other CYP3A4 substrate medications—drugs your liver processes with a specific enzyme. The documented interactions are Minor, but a quick search of your exact medications on this page will confirm whether any of yours are affected.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

If you take midazolam or other medications processed by your liver's CYP3A4 enzyme, check your exact drugs before starting this product—the interaction is Minor, but it's still worth confirming. Tangerine fruit eaten as food is generally well tolerated, though we don't have established evidence it works for cancer prevention.

If you're pregnant or breastfeeding, ask your pharmacist or doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tangerine Fruit, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435218836
Net contents 1 Ounce(s)
Market status On market
Date entered into DSLD Feb 21, 2023
DSLD ID 284728
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tangerine Fruit by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 Teaspoon(s)
Maximum serving Sizes:
0.25 Teaspoon(s)
Servings per container
28
UPC/BARCODE
064435218836
IngredientAmount% DV
Tangerine, Powder1000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2017 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Stir 1/4 of a teaspoon into a glass of water and consume 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Tangerine Fruit by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Tangerine Fruit by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container28 Amounts shown are per serving.

Tangerine, Powder

Interacts with
643 drugs
1000 mg per serving

Tangerine is a sweet citrus fruit that is a good source of vitamin C and other nutrients, and is widely enjoyed as food. While the peel and essential...

Tangerine, Powder monograph & interactions
Interaction report

Tangerine Fruit by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Tangerine Fruit?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
643Drugs
643 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Tangerine Fruit with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Tangerine, Powder2 drug types · 643 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4). This suggests that tangeretin may stimulate CYP3A4 activity. However, in humans, drinking tangerine juice 200 mL slightly delayed the absorption, but did not affect the metabolism, of midazolam, a CYP3A4 substrate. Theoretically, tangerine juice might increase CYP3A4 activity and decrease levels of drugs metabolized by this enzyme. However, this effect is unlikely.
Some drugs metabolized by CYP3A4 include amitriptyline (Elavil), amiodarone (Cordarone), citalopram (Celexa), felodipine (Plendil), lansoprazole (Prevacid), ondansetron (Zofran), prednisone (Deltasone, Orasone), sertraline (Zoloft), sibutramine (Meridia), and many others.

Likelihood Unlikely Evidence B
Midazolam (Versed)

In vitro, tangeretin, a constituent of tangerine, appears to increase the metabolism of midazolam in human liver microsomes by up to 52%. However, in humans, drinking tangerine juice 200 mL slightly delayed the absorption, but did not affect the metabolism, of midazolam. Theoretically, tangerine juice might increase the metabolism and reduce the effects of midazolam. However, this effect is unlikely.

Likelihood Unlikely Evidence B
The maker

Brand information

Manufacturer and brand details for Tangerine Fruit, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Tangerine Fruit by TerraVita Premium Collection: Common Questions

Does Tangerine Fruit by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Tangerine Fruit has a known interaction with 643 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tangerine Fruit contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is tangerine powder safe to use if I'm taking other medications?
Tangerine fruit has Minor interactions documented with midazolam and other CYP3A4 substrate medications, but real-world studies on tangerine juice showed the effect was very small. Use the medication checker on this page to see if any of your specific drugs are listed. If you're not sure, ask your pharmacist.
Can I use this if I'm pregnant or breastfeeding?
We don't have safety data on file for tangerine in pregnancy or while breastfeeding. Talk with your doctor or pharmacist for personalized advice before starting this product if you're pregnant, planning to become pregnant, or nursing.
Does tangerine powder help prevent cancer?
The evidence we have rates tangerine as insufficient to say whether it prevents cancer. There's not enough reliable data to claim it works for that purpose.
What are the side effects of tangerine powder?
Very few adverse effects have been reported when tangerine is eaten as food. One case report linked tangerine essential oil in fragrance to a skin reaction, but that's a topical exposure, not relevant to eating the powder. A thorough safety review hasn't been done, so uncommon effects might not be documented.
Is this concentrated tangerine extract or just the whole fruit powder?
This is tangerine fruit powder. The safety caution we have on file advises that concentrated extracts and essential oils of tangerine should be used with caution and medical advice. The fruit itself, as food, is fine.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tangerine Fruit label
Sources

Sources & How We Checked

Tangerine Fruit's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tangerine 3 references
  1. Yuan, J. M., Wang, X. L., Xiang, Y. B., Gao, Y. T., Ross, R. K., and Yu, M. C. Preserved foods in relation to risk of nasopharyngeal carcinoma in Shanghai, China. Int J Cancer 2000;85(3):358-363. DOI
  2. Backman, J. T., Maenpaa, J., Belle, D. J., Wrighton, S. A., Kivisto, K. T., and Neuvonen, P. J. Lack of correlation between in vitro and in vivo studies on the effects of tangeretin and tangerine juice on midazolam hydroxylation. Clin Pharmacol Ther 2000; PubMed
  3. Vilaplana, J. and Romaguera, C. Contact dermatitis from the essential oil of tangerine in fragrance. Contact Dermatitis 2002;46(2):108. PubMed

See these in context on the Tangerine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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