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Dietary supplement

Tongkat Ali 200:1 1200 mg Ingredients & Drug Interactions

by eXplicit Supplements

Tongkat Ali 200:1 1200 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Tongkat Ali 200:1 1200 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Tongkat Ali 200:1 1200 mg is a dietary supplement by eXplicit Supplements with 1 active ingredient. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Tongkat Ali Root Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Tongkat Ali 200:1 1200 mg by eXplicit Supplements

Ask about any prescription or over-the-counter medication and we check it for interactions with Tongkat Ali 200:1 1200 mg by eXplicit Supplements — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Tongkat Ali 200:1 1200 mg by eXplicit Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Tongkat Ali Root Extract at a 200:1 concentration, delivering 1,200 mg per capsule. Tongkat Ali (also called Eurycoma longifolia) is a traditional Southeast Asian herb used mainly for sexual health and male vitality.

The capsule also contains inactive ingredients — microcrystalline cellulose (a binder), magnesium stearate (a flow agent), and hypromellose (the capsule material itself).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Eurycoma Longifolia's overall clinical evidence instead.

Moderate

Some clinical evidence supports Eurycoma Longifolia for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Sexual desire — rated "Possibly Effective" (Natural Medicines).

The evidence supports Tongkat Ali for sexual desire, where it's rated Possibly Effective based on available research. For athletic performance, the data suggests it's Possibly Ineffective.

The evidence on back pain, osteoporosis, and diabetes is too weak or limited for us to rate it one way or the other — so we simply don't have enough reliable data yet.

The evidence, ingredient by ingredient Eurycoma Longifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tongkat Ali is generally well tolerated in short-term studies, but we don't have solid long-term safety data or consistent information about product quality across brands. The bigger concern is hormonal: the herb appears to increase testosterone levels, and if levels climb above the normal range, you could develop testosterone-related side effects including acne, insulin resistance, and liver stress.

Because of this and insufficient safety data, avoid it during pregnancy and while breastfeeding.

Side effects, ingredient by ingredient Eurycoma Longifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Eurycoma Longifolia.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist if you're on propranolol (Inderal) or any other blood-pressure or heart medication — Tongkat Ali can weaken propranolol's effect. Also double-check any drug that depends on CYP1A2, CYP2C19, or CYP2A6 enzymes to be cleared, and let us know if you're taking testosterone replacement or have low testosterone.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Consider Tongkat Ali if you're interested in boosting sexual desire and have checked your medications for interactions — especially if you take propranolol or rely on liver enzyme systems to clear your drugs. Skip it if you're pregnant, nursing, or have a history of hormonal sensitivity.

Talk to your pharmacist or doctor before starting, particularly if you take any blood pressure or heart medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tongkat Ali 200:1 1200 mg, straight from the product label.

Brand eXplicit Supplements
Barcode (UPC) 850032646994
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 310018
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tongkat Ali 200:1 1200 mg by eXplicit Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
850032646994
IngredientAmount% DV
Tongkat Ali Root Extract1200 mg--

Other ingredients: Microcrystalline Cellulose, Magnesium Stearate, Hypromellose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement take two (2) capsules per day with an 10 oz glass of water and food or as directed by your healthcare professional.

Precautions

Caution: Do not exceed recommended dose. Do not use if safety seal is damaged or missing.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Tongkat Ali 200:1 Eurycoma longifolia root 1200 mg per serving

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

GMP Good Manufacturing Practice FDA Registered Facility Made in the USA

Formulation

Made with all natural ingredients No artificial flavors No preservatives No soy, dairy or egg ingredients

General Statements

Come check out our other products: www.explicitsupplements.com

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Tongkat Ali 200:1 1200 mg by eXplicit Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Tongkat Ali 200:1 1200 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Tongkat Ali 200:1 1200 mg by eXplicit Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Tongkat Ali Root Extract

Interacts with
248 drugs
1200 mg per serving

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...

Tongkat Ali Root Extract monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Magnesium Stearate, Hypromellose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tongkat Ali 200:1 1200 mg by eXplicit Supplements Drug Interactions

Want to check YOUR meds against Tongkat Ali 200:1 1200 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
3 Moderate 245 Minor

Ingredients driving the most interactions

Tongkat Ali Root Extract 248

Individual Drug Interactions

The ingredients in Tongkat Ali 200:1 1200 mg interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in Tongkat Ali 200:1 1200 mg interact with drugs. Each result below shows which ingredient is responsible. Tongkat Ali Root Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Tongkat Ali 200:1 1200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Tongkat Ali Root Extract5 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
Tongkat Ali Root Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Tongkat Ali 200:1 1200 mg, from the product label.

eXplicit Supplements

See all eXplicit Supplements products
Name
iXanda Inc. dba explicit Supplements
City
Clarence
State
NY
ZipCode
14032
Phone Number
(716)-701-4092
Web Address
www.explicitsupplements.com
Pharmacist Counseling Corner

Tongkat Ali 200:1 1200 mg by eXplicit Supplements: Common Questions

Does Tongkat Ali 200:1 1200 mg by eXplicit Supplements interact with any medications?
Yes. Based on its ingredients, Tongkat Ali 200:1 1200 mg has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tongkat Ali 200:1 1200 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will Tongkat Ali actually improve my sexual desire?
The evidence suggests it possibly can — that's our rating based on available research. Results vary from person to person, and you'd need to try it to know if it works for you.
Is it safe to take long-term?
We don't have solid safety data for long-term use, so that's one reason to talk with your pharmacist before committing to it. Short-term studies show it's generally tolerated, but we need more information on extended use.
Can I take it while pregnant or breastfeeding?
No — there isn't enough safety data, and the herb's possible hormonal effects mean it's best to avoid it during pregnancy. Avoid it while breastfeeding as well until we know more.
What are the side effects of higher testosterone?
If Tongkat Ali pushes your testosterone above normal range, you might see acne, insulin resistance, or liver stress. That's why it matters to know your baseline and monitor how you feel.
Does Tongkat Ali help with athletic performance?
The evidence suggests it's probably not effective for that purpose, so there's no strong reason to use it specifically to boost your workouts.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Tongkat Ali 200:1 1200 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tongkat Ali 200:1 1200 mg label
Go deeper

The Full Monographs Behind Tongkat Ali 200:1 1200 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Eurycoma Longifolia

Interacts with 248 drugs

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....

Read the full Eurycoma Longifolia monograph →
Sources

Sources & How We Checked

Tongkat Ali 200:1 1200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eurycoma Longifolia 4 references
  1. Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
  2. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
  3. Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
  4. Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent

See these in context on the Eurycoma Longifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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