Tongkat Ali 200 mg Ingredients & Drug Interactions
by NutraBio
What is this page for?
First and foremost: checking Tongkat Ali 200 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Tongkat Ali 200 mg is a dietary supplement by NutraBio with 1 active ingredient. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are LJ100. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Tongkat Ali 200 mg by NutraBio
Ask about any prescription or over-the-counter medication and we check it for interactions with Tongkat Ali 200 mg by NutraBio — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Tongkat Ali 200 mg by NutraBio
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: LJ100, a water-based extract of Eurycoma longifolia root, often called Tongkat Ali. It's a traditional herbal root used primarily for sexual health.
The capsule also contains two inactive ingredients—hypromellose and water—which are the capsule material and a processing agent.
Does it work?
Moderate evidence
The evidence for Eurycoma longifolia shows it is possibly effective for sexual desire. For athletic performance, the data suggests it is possibly ineffective.
For back pain, osteoporosis, and diabetes, there isn't enough reliable evidence in our data to say whether it works or doesn't.
How safe is it?
Well-documented data
Eurycoma longifolia is generally well tolerated in short-term studies, but long-term safety and quality control of products aren't well established. The main safety concern is testosterone — the supplement can raise your testosterone levels, and if they go too high, you could develop acne, insulin resistance, liver stress, and other testosterone-related side effects.
The safety data advises against use during pregnancy and breastfeeding because there isn't enough information to know whether it's safe for you or your baby.
Meds to double-check
Moderate interaction found
Before you take this, double-check with us if you're on propranolol (Inderal) — this is the most serious concern. Also let us know if you take any medications that use your liver's enzyme systems (CYP1A2, CYP2C19, or CYP2A6 substrates) or testosterone replacement therapy, since the supplement could affect how they work.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Tongkat Ali may help with sexual desire if you're interested in that use, but don't take it if you're on propranolol without checking with your pharmacist first. It's also not for pregnancy or breastfeeding, and anyone taking medications metabolized by the liver should verify their drug list before starting.
Talk to your pharmacist about whether it's right for your situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Tongkat Ali 200 mg, straight from the product label.
| Brand | NutraBio |
|---|---|
| Barcode (UPC) | 649908217266 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2024 |
| DSLD ID | 318091 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Tongkat Ali 200 mg by NutraBio, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: Take 1 capsule daily as needed.
Precautions
Warning: Keep out of reach of children. Not for use by individuals under the age of 18.
Do not use if pregnant or nursing. Consult a physician before use if you have a medical condition or are taking any medication.
Discontinue use two weeks prior to surgery.
Processed in a facility and/or manufacturing line that also produces milk, tree nuts, nuts and soy.
Formulation
Check. Verify. Trust. View independent lab results Checkmysupps.com No proprietary blends Fully transparent
Manufactured in our GMP & FDA Inspected Facility
No added color, flavor, sweetener, or preservatives. Manufactured without lactose or gluten.
Maximum strength
General Statements
Since 1996
Wellness
Seals/Symbols
Made in USA with ingredients sourced worldwide
OU (Kosher)
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formula
LJ100
OU (Kosher)
FDA Statement of Identity
Botanical Supplement
Storage
Store in a cool dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Tongkat Ali 200 mg by NutraBio label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Tongkat Ali 200 mg by NutraBio
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
LJ100
Interacts with248 drugs
Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...
LJ100 monograph & interactionsOther (inactive) ingredients: Hypromellose, Water. These complete the product’s ingredient list but are not active constituents.
Tongkat Ali 200 mg by NutraBio Drug Interactions
HelloPharmacist Interaction Report
NutraBio's Tongkat Ali 200 mg contains a single active ingredient, LJ100 (Eurycoma longifolia), which does interact with some medications.
The most serious interaction is with propranolol (Inderal), a heart and blood pressure medication — the supplement can reduce propranolol levels by about 29%, potentially weakening its effect on your heart rate and blood pressure. This is a Moderate severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Eurycoma longifolia also theoretically weakens several other drug classes through effects on your liver's enzyme systems (CYP1A2, CYP2C19, and CYP2A6 substrates are all Minor interactions). Additionally, the ingredient may raise testosterone levels further if you're already taking testosterone replacement therapy (Minor severity).
Although we hold data on interactions with these medications, the enzyme-related effects have only been shown in test tubes, not in people yet. Still, if you take propranolol or any medication metabolized by your liver, run your exact drugs through the checker below before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Tongkat Ali 200 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Tongkat Ali 200 mg interact with 248 drugs. Click any drug to see the details.
1 of the 1 ingredient in Tongkat Ali 200 mg interact with drugs. Each result below shows which ingredient is responsible. LJ100
Hydrochlorothiazide, PropranololInderide
How Hydrochlorothiazide, Propranolol interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Propranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Lj100 + Hydrochlorothiazide, Propranolol interactionPropranololAngilol, Bedranol SR, Beta Prograne, Half Beta Prograne, Half-Inderal LA, Inderal +6 more
How Propranolol interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Propranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Lj100 + Propranolol interactionPropranolol HydrochlorideHemangeol
How Propranolol Hydrochloride interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Propranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Lj100 + Propranolol Hydrochloride interactionAbrocitinibCibinqo
How Abrocitinib interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
Read the full Lj100 + Abrocitinib interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Tongkat Ali 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Lj100Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Tongkat Ali 200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
LJ100
Propranolol (Inderal)
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.
Cytochrome P450 2A6 (Cyp2A6) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.
Testosterone
Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.
Brand information
Manufacturer and brand details for Tongkat Ali 200 mg, from the product label.
NutraBio
See all NutraBio products- Name
- NutraBio Labs, Inc.
- Street Address
- 564 Lincoln Blvd.
- City
- Middlesex
- State
- NJ
- ZipCode
- 08846
- Phone Number
- 732-748-8606
Tongkat Ali 200 mg by NutraBio: Common Questions
Does Tongkat Ali 200 mg by NutraBio interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take Tongkat Ali if I'm pregnant or breastfeeding?
What exactly is LJ100?
Does Tongkat Ali actually work for sexual desire?
What are the side effects of Tongkat Ali?
Is this safe to take long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Tongkat Ali 200 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Tongkat Ali 200 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Tongkat Ali 200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Eurycoma Longifolia 4 references
- Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
- Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
- Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
- Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC