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Dietary supplement

Tongkat Ali 200 mg Ingredients & Drug Interactions

by NutraBio

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Tongkat Ali 200 mg is a dietary supplement by NutraBio with 1 active ingredient. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are LJ100. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Tongkat Ali 200 mg by NutraBio

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: LJ100, a water-based extract of Eurycoma longifolia root, often called Tongkat Ali. It's a traditional herbal root used primarily for sexual health.

The capsule also contains two inactive ingredients—hypromellose and water—which are the capsule material and a processing agent.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: male vitality and testosterone support.
  • We looked for evidence on: Age-related testosterone deficiency, Athletic performance, Erectile dysfunction (ED), Male Infertility, Muscle strength, Sexual desire — and 4 related terms.
  • The strongest evidence on file: Eurycoma Longifolia is rated "Possibly Effective" for Sexual desire (Natural Medicines).
  • Also on file: Eurycoma Longifolia is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Eurycoma Longifolia is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED), Muscle strength, Age-related testosterone deficiency, Male Infertility.

The evidence for Eurycoma longifolia shows it is possibly effective for sexual desire. For athletic performance, the data suggests it is possibly ineffective.

For back pain, osteoporosis, and diabetes, there isn't enough reliable evidence in our data to say whether it works or doesn't.

The evidence, ingredient by ingredient Eurycoma Longifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Eurycoma longifolia is generally well tolerated in short-term studies, but long-term safety and quality control of products aren't well established. The main safety concern is testosterone — the supplement can raise your testosterone levels, and if they go too high, you could develop acne, insulin resistance, liver stress, and other testosterone-related side effects.

The safety data advises against use during pregnancy and breastfeeding because there isn't enough information to know whether it's safe for you or your baby.

Side effects, ingredient by ingredient Eurycoma Longifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Eurycoma Longifolia.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check with us if you're on propranolol (Inderal) — this is the most serious concern. Also let us know if you take any medications that use your liver's enzyme systems (CYP1A2, CYP2C19, or CYP2A6 substrates) or testosterone replacement therapy, since the supplement could affect how they work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Tongkat Ali may help with sexual desire if you're interested in that use, but don't take it if you're on propranolol without checking with your pharmacist first. It's also not for pregnancy or breastfeeding, and anyone taking medications metabolized by the liver should verify their drug list before starting.

Talk to your pharmacist about whether it's right for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tongkat Ali 200 mg, straight from the product label.

Brand NutraBio
Barcode (UPC) 649908217266
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 318091
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tongkat Ali 200 mg by NutraBio, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
Servings per container
60
UPC/BARCODE
649908217266
IngredientAmount% DV
LJ100200 mg--

Other ingredients: Hypromellose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Take 1 capsule daily as needed.

Precautions

Warning: Keep out of reach of children. Not for use by individuals under the age of 18.

Do not use if pregnant or nursing. Consult a physician before use if you have a medical condition or are taking any medication.

Discontinue use two weeks prior to surgery.

Processed in a facility and/or manufacturing line that also produces milk, tree nuts, nuts and soy.

Formulation

Check. Verify. Trust. View independent lab results Checkmysupps.com No proprietary blends Fully transparent

Manufactured in our GMP & FDA Inspected Facility

No added color, flavor, sweetener, or preservatives. Manufactured without lactose or gluten.

Maximum strength

General Statements

Since 1996

Wellness

Seals/Symbols

Made in USA with ingredients sourced worldwide

OU (Kosher)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

LJ100

OU (Kosher)

FDA Statement of Identity

Botanical Supplement

Storage

Store in a cool dry place.

See for yourself

Tongkat Ali 200 mg by NutraBio label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Tongkat Ali 200 mg by NutraBio

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

LJ100

Interacts with
248 drugs
200 mg per serving Form: Tongkat Ali Root Extract

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...

LJ100 monograph & interactions

Other (inactive) ingredients: Hypromellose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tongkat Ali 200 mg by NutraBio Drug Interactions

Want to check YOUR meds against Tongkat Ali 200 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

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248Drugs
3 Moderate 245 Minor

Ingredients driving the most interactions

LJ100 248

Each ingredient & the kinds of drugs it affects

For each ingredient in Tongkat Ali 200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

LJ1005 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Tongkat Ali 200 mg, from the product label.

NutraBio

See all NutraBio products
Name
NutraBio Labs, Inc.
Street Address
564 Lincoln Blvd.
City
Middlesex
State
NJ
ZipCode
08846
Phone Number
732-748-8606
Pharmacist Counseling Corner

Tongkat Ali 200 mg by NutraBio: Common Questions

Does Tongkat Ali 200 mg by NutraBio interact with any medications?
Yes. Based on its ingredients, Tongkat Ali 200 mg has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tongkat Ali 200 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Tongkat Ali if I'm pregnant or breastfeeding?
No — the safety data advises against it in both cases. There isn't enough information to know whether it's safe for you or your baby, so talk with your doctor or pharmacist about your options.
What exactly is LJ100?
LJ100 is a water-based extract of Eurycoma longifolia root, the plant commonly called Tongkat Ali. It's the active ingredient in this supplement.
Does Tongkat Ali actually work for sexual desire?
The evidence says it's possibly effective for sexual desire, meaning there's some support for it but it's not a sure thing. Individual results vary.
What are the side effects of Tongkat Ali?
The main concern is that it can raise testosterone levels. If testosterone goes too high, you might develop acne, insulin resistance, liver stress, and other hormone-related effects.
Is this safe to take long-term?
The studies show it's generally well tolerated short-term, but long-term safety isn't well established, and product quality can vary. Your pharmacist can discuss whether long-term use makes sense for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Tongkat Ali 200 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tongkat Ali 200 mg label
Sources

Sources & How We Checked

Tongkat Ali 200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eurycoma Longifolia 4 references
  1. Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
  2. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
  3. Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
  4. Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent

See these in context on the Eurycoma Longifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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