Tri-Iodine Chocolate 500 mcg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Tri-Iodine Chocolate 500 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Tri-Iodine Chocolate 500 mcg is a dietary supplement by Terry Naturally with 1 active ingredient. Its ingredients are commonly taken for preventing iodine deficiency, supporting thyroid hormone production, general energy and metabolism support.Based on those ingredients, 7 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Iodine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
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HelloPharmacist Scorecard of Tri-Iodine Chocolate 500 mcg by Terry Naturally
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Tri-Iodine Chocolate contains 3 active iodine ingredients: potassium iodide, sodium iodide, and molecular iodine, delivering 500 micrograms of iodine total. The inactive ingredients include xylitol, natural chocolate and vanilla flavors, stearic acid, vegetable-source magnesium stearate, and silica—these are fillers and binders that help form and flavor the tablet.
Does it work?
Strong evidence
Based on the data we hold, iodine is likely effective for preventing or treating iodine deficiency and for radiation exposure (like after a nuclear event or certain medical procedures). It's rated possibly effective for oral mucositis (mouth sores) and periodontitis (gum disease).
For other uses, the evidence isn't established in our data.
How safe is it?
Well-documented data
Iodine is well tolerated in normal dietary amounts, but high doses can trigger thyroid problems like goiter (enlarged thyroid), hypothyroidism (underactive thyroid), or hyperthyroidism (overactive thyroid). Common side effects at higher intakes include nausea, abdominal upset, diarrhea, headache, and a metallic taste.
Rarely, some people can have a hypersensitivity reaction with symptoms like swelling, rash, or fever. Chronic high-dose use has also been linked to acneform skin lesions (iododerma).
In pregnancy, adequate iodine is important for the baby, but use only the amount your doctor advises and avoid high-dose products. During breastfeeding, some iodine passes into breast milk, so follow your doctor's guidance.
If you're unsure about dosing in pregnancy or while nursing, talk with your doctor or pharmacist.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your doctor or pharmacist if you're on lithium, any antithyroid medications (like propylthiouracil or methimazole), or amiodarone. These are the medication types with documented Moderate-severity interactions.
All three concern thyroid function, so your doctor may want to monitor you or adjust dosing.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This supplement is for people who need iodine to prevent deficiency or for specific medical uses like radiation protection—not for everyday wellness. If you take lithium, an antithyroid drug, or amiodarone, you need to check with your doctor or pharmacist before starting.
Even if you don't take those drugs, high-dose iodine can affect thyroid function, so it's worth discussing with your own healthcare provider, especially if you have a thyroid condition.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2018.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Tri-Iodine Chocolate 500 mcg, straight from the product label.
| Brand | Terry Naturally |
|---|---|
| Barcode (UPC) | 367703274467 |
| Net contents | 60 Chewable Tablet(s) |
| Market status | On market |
| Date entered into DSLD | May 24, 2018 |
| DSLD ID | 177291 |
| Product type | Mineral |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Tri-Iodine Chocolate 500 mcg by Terry Naturally, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Iodine | 500 mcg | 333% |
| Potassium Iodide | 189 mcg | -- |
| Sodium Iodide | 305 mcg | -- |
| molecular Iodine | 6 mcg | -- |
Other ingredients: Xylitol, natural Chocolate flavor, natural Vanilla flavor, Stearic Acid, Vegetable Source Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Money-back guarantee
Chewable Supports strong cellular defense and hormone balance For your good health Terry
Are you getting the iodine you need from diet alone? Iodine consumption has dropped 50% in the last 30 years. This “missing mineral” is critical for multiple reasons and reliable food sources can be difficult to find. Research has shown you need different forms of iodine to target different health systems.
You can't live without Iodine Every cell in your body requires iodine to keep it functioning properly. But each day, you are exposed to the iodine blockers: chlorine, bromide from bromated baked goods and soft drinks, and fluoride in tap water, just to name a few.
Breast, prostate and colon health Hormone balance Menopause relief Healthy detoxification Cellular defense
BX27446.01
Formula
Tri-Iodine provides three beneficial forms of iodine, an essential trace element. Each capsule supplies 0.5 mg total iodine (equivalent to 500 mcg).
Star-K
Three forms of Iodine for optimum support Potassium Iodide Sodium Iodide Molecular Iodine
Tri-Iodine provides three beneficial forms of iodine to nourish multiple body systems: a blend of potassium iodide, sodium iodide, and molecular iodine. Three forms of iodine provide a wider spectrum of benefits: - Potassium iodide and sodium iodide for hormone balance and immune health. - Molecular iodine for breast, prostate, colon, and cellular health.
Suggested/Recommended/Usage/Directions
Recommendations: 1 chocolate chewable tablet daily with food. For long term use, consult a healthcare practitioner.
Precautions
If pregnant or nursing, consult a healthcare practitioner before using.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General
JC 34 91 + 3(5,6)EP L27446.01
FDA Statement of Identity
Dietary Supplement
Formulation
No sugar, salt, yeast, wheat, gluten, soy, dairy products, artificial coloring, artificial flavoring, or artificial preservatives.
Vegan
Seals/Symbols
Star-K
Brand IP Statement(s)
Terry Naturally EuroPharma
Tri-Iodine can help. It supplies the crucial support you need for: - Breast, uterine, prostate, and colon health - Hormone balance and menopause relief - Detoxification of environmental stressors - Cellular defense throughout the body
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Tri-Iodine Chocolate 500 mcg by Terry Naturally label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Tri-Iodine Chocolate 500 mcg by Terry Naturally
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Chewable Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.
Iodine
Interacts with7 drugs
Iodine is an essential mineral your body needs to make thyroid hormones, and most people get enough from iodized salt, dairy, and seafood. Supplements...
Iodine monograph & interactionsOther (inactive) ingredients: Xylitol, Natural Chocolate flavor, Natural Vanilla flavor, Stearic Acid, Vegetable Source Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
Tri-Iodine Chocolate 500 mcg by Terry Naturally Drug Interactions
HelloPharmacist Interaction Report
Tri-Iodine Chocolate 500 mcg by Terry Naturally contains three forms of iodine—potassium iodide, sodium iodide, and molecular iodine—that share the same interaction profile.
The most serious documented interactions are Moderate in severity and involve lithium, antithyroid drugs, and amiodarone (a heart rhythm medication). Altogether, these interactions span 7 individual medications.
Read the full breakdown — every affected drug type, severity by severity
With lithium, the iodine in this product might add to lithium's effect on thyroid function and could reduce thyroid activity in otherwise healthy adults. Your thyroid function should be monitored if you're on both.
Antithyroid drugs (used to treat overactive thyroid) may have their effects altered by high-dose iodine, since iodine itself can swing thyroid function either direction depending on your history. If you take amiodarone, which already contains a high amount of iodine, adding this supplement could push iodine levels too high and hurt thyroid function—again, monitoring is key.
Use the medication checker below to verify your exact drugs before starting. If you're on any of these three categories, clear it with your doctor or pharmacist first.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Tri-Iodine Chocolate 500 mcg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Tri-Iodine Chocolate 500 mcg interact with 7 drugs. Click any drug to see the details.
1 of the 1 ingredient in Tri-Iodine Chocolate 500 mcg interact with drugs. Each result below shows which ingredient is responsible. Iodine
AmiodaroneCordarone, Pacerone
How Amiodarone interacts with Tri-Iodine Chocolate 500 mcg — through 1 ingredient. Tap an ingredient for the detail:
Molecular IodineAmiodarone (cordarone) Moderate
Interaction Summary
Combining iodine with amiodarone might cause excessively high iodine levels.
Read the full Molecular Iodine + Amiodarone interactionCarbimazoleNeo-Mercazole
How Carbimazole interacts with Tri-Iodine Chocolate 500 mcg — through 1 ingredient. Tap an ingredient for the detail:
Molecular IodineAntithyroid Drugs Moderate
Interaction Summary
Iodine might alter the effects of antithyroid drugs.
Read the full Molecular Iodine + Carbimazole interactionLithium Carbonate (prescription Drug)Eskalith, Lithium Carbonate
How Lithium Carbonate (prescription Drug) interacts with Tri-Iodine Chocolate 500 mcg — through 1 ingredient. Tap an ingredient for the detail:
Molecular IodineLithium Moderate
Interaction Summary
Combining iodine with lithium might have additive hypothyroid effects.
Read the full Molecular Iodine + Lithium Carbonate (prescription Drug) interactionMethenamine MandelateMandelamine, Methimazole
How Methenamine Mandelate interacts with Tri-Iodine Chocolate 500 mcg — through 1 ingredient. Tap an ingredient for the detail:
Molecular IodineAntithyroid Drugs Moderate
Interaction Summary
Iodine might alter the effects of antithyroid drugs.
Read the full Molecular Iodine + Methenamine Mandelate interactionMethimazoleTapazole
How Methimazole interacts with Tri-Iodine Chocolate 500 mcg — through 1 ingredient. Tap an ingredient for the detail:
Molecular IodineAntithyroid Drugs Moderate
Interaction Summary
Iodine might alter the effects of antithyroid drugs.
Read the full Molecular Iodine + Methimazole interactionPotassium Iodide (prescription Drug)Thyro-Block
How Potassium Iodide (prescription Drug) interacts with Tri-Iodine Chocolate 500 mcg — through 1 ingredient. Tap an ingredient for the detail:
Molecular IodineAntithyroid Drugs Moderate
Interaction Summary
Iodine might alter the effects of antithyroid drugs.
Read the full Molecular Iodine + Potassium Iodide (prescription Drug) interactionPropylthiouracil, PtuPropylthiouracil
How Propylthiouracil, Ptu interacts with Tri-Iodine Chocolate 500 mcg — through 1 ingredient. Tap an ingredient for the detail:
Molecular IodineAntithyroid Drugs Moderate
Interaction Summary
Iodine might alter the effects of antithyroid drugs.
Read the full Molecular Iodine + Propylthiouracil, Ptu interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Tri-Iodine Chocolate 500 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Iodine
Amiodarone (Cordarone)
Combining iodine with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with iodine might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.
Antithyroid Drugs
Iodine might alter the effects of antithyroid drugs.
Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking iodine while using antithyroid drugs could alter the effects of the antithyroid drugs.
Lithium
Combining iodine with lithium might have additive hypothyroid effects.
Lithium can inhibit thyroid function. Several case reports suggest that concomitant use of lithium and potassium iodide can reduce thyroid function in otherwise healthy adults. Monitor thyroid function.
Brand information
Manufacturer and brand details for Tri-Iodine Chocolate 500 mcg, from the product label.
Terry Naturally
See all Terry Naturally products- Name
- EuroPharma, Inc.
- City
- Green Bay
- State
- WI
- ZipCode
- 54311
- Phone Number
- (866) 807-2731
- Web Address
- EuroPharmaUSA.com
Tri-Iodine Chocolate 500 mcg by Terry Naturally: Common Questions
Does Tri-Iodine Chocolate 500 mcg by Terry Naturally interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What's iodine actually for?
Can I take this if I'm pregnant?
What are the most common side effects?
Can iodine affect my thyroid?
Is there anything in this supplement besides the iodine?
Will this help with iodine deficiency?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Tri-Iodine Chocolate 500 mcg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Tri-Iodine Chocolate 500 mcg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Tri-Iodine Chocolate 500 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 28 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Iodine 28 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
- Ghent WR, Eskin BA, Low DA, Hill LP. Iodine replacement in fibrocystic disease of the breast. Can J Surg 1993;36:453-60.
- Potassium iodide for nuclear exposure. Pharmacist's Letter/Prescriber's Letter 2001;17(12):171214.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Cabezas C, Bustamante B, Holgado W, Begue RE. Treatment of cutaneous sporotrichosis with one daily dose of potassium iodide. Pediatr Infect Dis J 1996;15:352-4. PubMed
- Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7. PubMed
- Yarrington CD, Pearce EN. Dietary iodine in pregnancy and postpartum. Clin Obstet Gynecol 2011;54:459-70. PubMed
- Teng, W., Shan, Z., Teng, X., Guan, H., Li, Y., Teng, D., Jin, Y., Yu, X., Fan, C., Chong, W., Yang, F., Dai, H., Yu, Y., Li, J., Chen, Y., Zhao, D., Shi, X., Hu, F., Mao, J., Gu, X., Yang, R., Tong, Y., Wang, W., Gao, T., and Li, C. Effect of iodine int
- Crawford, B. A., Cowell, C. T., Emder, P. J., Learoyd, D. L., Chua, E. L., Sinn, J., and Jack, M. M. Iodine toxicity from soy milk and seaweed ingestion is associated with serious thyroid dysfunction. Med J Aust. 10-4-2010;193(7):413-415. PubMed
- Ohkuma, M. Molluscum contagiosum treated with iodine solution and salicylic acid plaster. Int J Dermatol. 1990;29(6):443-445. PubMed
- Connelly KJ, Boston BA, Pearce EN, Sesser D, Snyder D, Braverman LE, Pino S, LaFranchi SH. Congenital hypothyroidism caused by excess prenatal maternal iodine ingestion. J Pediatr. 2012 Oct;161(4):760-2. PubMed
- Hoang TD, Mai VQ, Clyde PW, Shakir MK. Over-the-counter-drug-induced thyroid disorders. Endocr Pract. 2013 Mar-Apr;19(2):268-74. PubMed
- Kasahara T, Narumi S, Okasora K, Takaya R, Tamai H, Hasegawa T. Delayed onset congenital hypothyroidism in a patient with DUOX2 mutations and maternal iodine excess. Am J Med Genet A. 2013 Jan;161A(1):214-7.
- Murcia M, Rebagliato M, Iñiguez C, Lopez-Espinosa MJ, Estarlich M, Plaza B, Barona-Vilar C, Espada M, Vioque J, Ballester F. Effect of iodine supplementation during pregnancy on infant neurodevelopment at 1 year of age. Am J Epidemiol. 2011 Apr 1;173(7):8 PubMed
- Sang Z, Wang PP, Yao Z, Shen J, Halfyard B, Tan L, Zhao N, Wu Y, Gao S, Tan J, Liu J, Chen Z, Zhang W. Exploration of the safe upper level of iodine intake in euthyroid Chinese adults: a randomized double-blind trial. Am J Clin Nutr. 2012 Feb;95(2):367-73 PubMed
- Speeckaert MM, Speeckaert R, Wierckx K, Delanghe JR, Kaufman JM. Value and pitfalls in iodine fortification and supplementation in the 21st century. Br J Nutr. 2011 Oct;106(7):964-73. PubMed
- Yun SE, Kang Y, Bae EJ, Hwang K, Jang HN, Cho HS, Chang SH, Park DJ. Iodine-induced thyrotoxic hypokalemic paralysis after ingestion of Salicornia herbace. Ren Fail. 2014 Apr;36(3):461-3.
- Iodine Hypersensitivity. Pharmacist's Letter/Prescriber's Letter 2011; 27(5):270504.
- Hammel JA, Selby JC. Pustular eruption in a patient with cancer treated with complementary and alternative medicine. JAMA Dermatology 2017 October; E1. doi: 10.1001/jamadermatol.2017.3749. [Epub ahead of print] PubMed
- Gil GS, Smith BW, Guerra JR, Williams WT. Acute Delirium in a Hypothyroid Patient Precipitated by Iodine Supplements Use. Am J Ther. 2018;25(6):e717-e718. PubMed
- Hamby T, Kunnel N, Dallas JS, Wilson DP. Maternal iodine excess: an uncommon cause of acquired neonatal hypothyroidism. J Pediatr Endocrinol Metab. 2018;31(9):1061-1064. PubMed
- Censi S, Watutantrige-Fernando S, Groccia G, et al. The Effects of Iodine Supplementation in Pregnancy on Iodine Status, Thyroglobulin Levels and Thyroid Function Parameters: Results from a Randomized Controlled Clinical Trial in a Mild-to-Moderate Iodine
- Rovner MS, Wolf BJ, Rubin M, et al. Instillation of 5% Povidone-Iodine Ophthalmic Drops Decreases the Respiratory Rate in Children Undergoing Strabismus Surgery: A Randomized Controlled Trial. J Pediatr Ophthalmol Strabismus. 2019;56(6):378-382. PubMed
- Guenezan J, Garcia M, Strasters D, et al. Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Nasopharyngeal Viral Load in Patients With COVID-19: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2021;147(4):400-401. PubMed
- Fan L, Tian Q, Xiu C, et al. High Iodine Nutrition May Be a Risk Factor for Cervical Lymph Node Metastasis in Papillary Thyroid Cancer Patients. Ann Nutr Metab 2021;77(2):90-99. PubMed
- Li F, Wan S, Zhang L, et al. A Meta-Analysis of the Effect of Iodine Excess on the Intellectual Development of Children in Areas with High Iodine Levels in their Drinking Water. Biol Trace Elem Res 2022;200(4):1580-1590. PubMed
- Mou Y, Qu T, Wang R, Zhang Y, He Z, Gu S. The association of high-fluoride and high-iodine combined exposure with dental fluorosis and goiter: a meta-analysis. Environ Geochem Health 2023;45(6):3143-3153. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC