Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Trifal Ingredients & Drug Interactions

by Ayush Herbs

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Trifal is a dietary supplement by Ayush Herbs with 3 active ingredients. Its ingredients are commonly taken for antioxidant support, cholesterol and heart health, immune support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Indian gooseberry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Trifal by Ayush Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Trifal contains three active ingredients: Indian gooseberry, chebulic myrobalan, and beleric myrobalan. This combination is a traditional Ayurvedic formulation.

The product is delivered in a vegetarian capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Indian Gooseberry's overall clinical evidence instead.

Moderate

Some clinical evidence supports Indian Gooseberry for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Dyslipidemia — rated "Possibly Effective" (Natural Medicines).
  • On file: Gastroesophageal reflux disease (GERD) — rated "Possibly Effective" (Natural Medicines).

Indian gooseberry in this formula has been rated possibly effective for gastroesophageal reflux disease (GERD) and dyslipidemia (abnormal blood lipid levels). For high cholesterol (hypercholesterolemia) and hair loss (androgenic alopecia), the evidence we hold is insufficient to rate it.

We have no effectiveness data on file for the other two ingredients in this product.

The evidence, ingredient by ingredient Indian Gooseberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Indian gooseberry is generally well tolerated when used as food, but its safety at supplement doses is less studied. The safety data available advises against it during pregnancy, and there is too little reliable safety information during breastfeeding to recommend its use.

In clinical trials, stomach discomfort or indigestion occurred in a small number of participants; fatigue and musculoskeletal pain were each reported by very few individuals.

Side effects, ingredient by ingredient Indian Gooseberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Indian Gooseberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before adding this product if you take blood thinners or antiplatelet drugs (anticoagulants), diabetes medications, aspirin, or clopidogrel (Plavix). All carry a Moderate interaction with Indian gooseberry.

We could not check interactions for the other two ingredients, so run your full medication list through the tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you take blood thinners, diabetes medications, or aspirin, talk to your pharmacist or doctor before starting Trifal — the Indian gooseberry in it may affect how these work. If you're pregnant or breastfeeding, the safety data advises against this product.

For everyone else, it's generally well tolerated, though stomach upset is possible.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Trifal, straight from the product label.

Brand Ayush Herbs
Barcode (UPC) 891501001371
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD May 24, 2013
DSLD ID 21532
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Trifal by Ayush Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
891501001371
IngredientAmount% DV
Indian gooseberry167 mg--
Chebulic myrobalan167 mg--
Beleric myrobalan167 mg--

Other ingredients: Vegetarian Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep Away From Reach Of Children

DO NOT USE IF SEAL IS BROKEN.

Warning: If pregnant, consult your physician before using this or any other product.

General Statements

Ayurveda ~ Wealth of Health

ADH 020910 02 2013

Formulation

Vegetarian

FDA Statement of Identity

DIETARY SUPPLEMENT

Suggested/Recommended/Usage/Directions

SUGGESTED USE: One capsule three times daily with a meal or as directed by your physician.

See for yourself

Trifal by Ayush Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Trifal by Ayush Herbs

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Indian gooseberry

Interacts with
208 drugs
167 mg per serving

Indian gooseberry (amla) is a vitamin C-rich fruit used in Ayurvedic medicine for many purposes, from antioxidant support to cholesterol and digestion...

Indian gooseberry monograph & interactions

Chebulic myrobalan

167 mg per serving

Beleric myrobalan

167 mg per serving

Other (inactive) ingredients: Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Trifal by Ayush Herbs Drug Interactions

Want to check YOUR meds against Trifal?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Trifal with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Indian gooseberry4 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking Indian gooseberry 500 mg along with clopidogrel 75 mg or ecosprin 75 mg, as a single dose or for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg or ecosprin 75 mg alone. Until more is known, use caution when taking Indian gooseberry in combination with anticoagulant/antiplatelet drugs.

Likelihood Possible Evidence B
Antidiabetes Drugs

Taking Indian gooseberry with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking Indian gooseberry fruit or fruit extract alone or in conjunction with antidiabetes medications can lower blood glucose levels. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Aspirin

Theoretically, Indian gooseberry may increase the risk of bleeding if used with aspirin; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with ecosprin 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus ecosprin 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with ecosprin 75 mg alone.

Likelihood Possible Evidence B
Clopidogrel (Plavix)

Theoretically, Indian gooseberry may increase the risk of bleeding if used with clopidogrel; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with clopidogrel 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus clopidogrel 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg alone.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Trifal, from the product label.

Ayush Herbs

See all Ayush Herbs products
Name
Ayush Herbs, Inc.
City
Redmond
State
WA
ZipCode
98052
Web Address
www.ayush.com
Pharmacist Counseling Corner

Trifal by Ayush Herbs: Common Questions

Does Trifal by Ayush Herbs interact with any medications?
Yes. Based on its ingredients, Trifal has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Trifal contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Trifal used for?
This formula contains Indian gooseberry, which has been studied for GERD (acid reflux) and high blood lipids — both are rated possibly effective. The other ingredients haven't been rated for effectiveness in our data. Talk to your pharmacist about whether it's right for your goals.
Is it safe to take while pregnant or breastfeeding?
No — the safety data advises against Indian gooseberry during pregnancy, and there isn't enough reliable information during breastfeeding. Talk with your doctor before considering it.
What side effects has it caused in trials?
Stomach discomfort or indigestion were reported by a small number of people in clinical trials. Fatigue and muscle or joint pain each occurred in very few individuals. Most people tolerate it well.
Can I take it with my diabetes medication?
Indian gooseberry may lower your blood sugar further, so it's a Moderate interaction. Your doctor may need to adjust your diabetes medication dose. Check with them before starting.
What are chebulic myrobalan and beleric myrobalan?
They're the other two active ingredients in this traditional Ayurvedic blend, but we hold no interaction or effectiveness data for them. Your pharmacist can tell you more about their traditional uses.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Trifal label
Sources

Sources & How We Checked

Trifal's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Indian Gooseberry 6 references
  1. Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
  2. Fatima N, Pingali U, Muralidhar N. Study of pharmacodynamic interaction of Phyllanthus emblica extract with clopidogrel and ecosprin in patients with type II diabetes mellitus. Phytomedicine. 2014;21(5):579-85. PubMed
  3. Shanmugarajan D, Girish C, Harivenkatesh N, Chanaveerappa B, Prasanna Lakshmi NC. Antihypertensive and pleiotropic effects of Phyllanthus emblica extract as an add-on therapy in patients with essential hypertension-A randomized double-blind placebo-contro
  4. Akhtar MS, Ramzan A, Ali A, Ahmad M. Effect of amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients. Int J Food Sci Nutr. 2011;62(6):609-16.
  5. Usharani P, Fatima N, Muralidhar N. Effects of Phyllanthus emblica extract on endothelial dysfunction and biomarkers of oxidative stress in patients with type 2 diabetes mellitus: a randomized, double-blind, controlled study. Diabetes Metab Syndr Obes. 20 PubMed
  6. Majeed M, Mundkur L, Paulose S, Nagabhushanam K. Novel Emblica officinalis extract containing ß-glucogallin vs. metformin: a randomized, open-label, comparative efficacy study in newly diagnosed type 2 diabetes mellitus patients with dyslipidemia. Food Fu

See these in context on the Indian Gooseberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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