Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

TrueHNS Ingredients & Drug Interactions

by NatureCity

TrueHNS label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking TrueHNS against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

TrueHNS is a dietary supplement by NatureCity with 3 active ingredients. Its ingredients are commonly taken for source of silica for hair, skin, and nails, bone and joint support, general nutrition (cooked shoots as food).Based on those ingredients, 5 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Orgen-Si. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against TrueHNS by NatureCity

Ask about any prescription or over-the-counter medication and we check it for interactions with TrueHNS by NatureCity — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of TrueHNS by NatureCity

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

TrueHNS has 3 active ingredients. Orgen-Si is derived from bamboo and is included for dental health, though the evidence for that use isn't established in our data.

Orgen-Bio is biotin, a B vitamin that's proven effective for biotin deficiency. Cynatine HNS rounds out the formula, but we don't have detailed information on file about its purpose or effects.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: improve appearance and strength of hair, nails, skin.
  • We looked for evidence on: Biotin deficiency, Brittle nails, hair loss, nail health, skin health.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).
  • Also on file: Biotin is rated "Insufficient Reliable Evidence To Rate" for Brittle nails.

Biotin in this product is likely effective for biotin deficiency—a real condition where your body doesn't get enough of this B vitamin. For the other ingredients, the evidence we hold doesn't support their use.

Bamboo hasn't shown enough reliable evidence for dental caries (cavities), and biotin itself hasn't shown benefit for multiple sclerosis or seborrheic dermatitis. We have no effectiveness data for Cynatine HNS.

The evidence, ingredient by ingredient Bamboo Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at higher doses, because your body gets rid of the excess through urine. A small number of people taking high-dose biotin have reported mild diarrhea.

Bamboo shoots eaten as food are safe when properly cooked, but supplement safety isn't well studied. Bamboo is a source of cyanide compounds, though boiling and proper processing eliminate the risk in food—we just don't have solid data on concentrated supplements.

Raw shoots can be toxic. During pregnancy, there isn't enough safety data on bamboo supplements, so they're best avoided.

While breastfeeding, the safety of bamboo supplements isn't known; stick with food sources unless your doctor clears a concentrated extract. For biotin, the amounts in food and prenatal vitamins are fine, but check with your doctor before taking high-dose supplements while pregnant or nursing.

Side effects, ingredient by ingredient Bamboo Biotin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Bamboo.
  • The most serious interaction on file is rated Moderate.
  • For scale: 5 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antithyroid medications for overactive thyroid, double-check with us before using TrueHNS—the bamboo ingredient may increase their effects and side effects. No other interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product might interest someone with a documented biotin deficiency or anyone looking to support dental health, though the dental evidence is weak. If you take an antithyroid drug, talk to your pharmacist before starting—there's a documented interaction with the bamboo ingredient.

Pregnant or breastfeeding? Check with your doctor first, especially about the bamboo component.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about TrueHNS, straight from the product label.

Brand NatureCity
Barcode (UPC) 859003007307
Net contents 60 Veggie Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 320942
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for TrueHNS by NatureCity, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
859003007307
IngredientAmount% DV
Cynatine HNS500 mg--
Orgen-Si20 mg--
Orgen-Bio1000 mcg3333%

Other ingredients: Hypromellose, Rice Flour, Stearic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Each serving contains two (2) capsules. Take (1) one serving per day or as directed by a healthcare practitioner.

Formulation

TrueHNS helps improve the appearance and strength of hair, nails and skin from the inside.

Non GMO Soy free Gluten free BPA free

Precautions

Keep out of reach of children

Do not use if seal is broken or missing

Storage

Store in a cool dry place

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Blended & packaged in the USA

Formula

Keratin, Biotin & Bamboo Silica

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Cynatine HNS is a registered trademark of Roxlor, LLC. Orgen-Bio and Orgen-Si are trademarks of Orgenetics, Inc.

General Statements

To re-order call toll free 1-800-593-2563

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

TrueHNS by NatureCity label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

TrueHNS label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in TrueHNS by NatureCity

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Cynatine HNS

500 mg per serving Form: Soluble Keratin

Orgen-Si

Interacts with
5 drugs
20 mg per serving Form: Bamboo Extract

Bamboo is a giant grass whose shoots are eaten as food and whose leaves and silica-rich extracts are sold as supplements, often for hair, skin, nail,...

Orgen-Si monograph & interactions

Orgen-Bio

No known
interactions
1000 mcg per serving Form: Biotin

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Orgen-Bio monograph & interactions

Other (inactive) ingredients: Hypromellose, Rice Flour, Stearic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

TrueHNS by NatureCity Drug Interactions

Want to check YOUR meds against TrueHNS?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
5Drugs
5 Moderate

Ingredients driving the most interactions

Orgen-Si 5

Individual Drug Interactions

The ingredients in TrueHNS interact with 5 drugs. Click any drug to see the details.

1 of the 3 ingredients in TrueHNS interact with drugs. Each result below shows which ingredient is responsible. Orgen-Si

Each ingredient & the kinds of drugs it affects

For each ingredient in TrueHNS with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Orgen-Si1 drug type · 5 drugs

Antithyroid Drugs

Theoretically, long-term bamboo use might increase the effects and adverse effects of antithyroid drugs, possibly leading to hypothyroidism.
Animal research suggests that long-term consumption of bamboo shoot can decrease thyroid peroxidase activity, as well as levels of thyroxine (T4) and triiodothyronine (T3). This effect has not yet been reported in humans.

Likelihood Possible Evidence D
Orgen-Si full monograph & interactions
The maker

Brand information

Manufacturer and brand details for TrueHNS, from the product label.

NatureCity

See all NatureCity products
Name
NatureCity
Street Address
900 Broken Sound Parkway NW
City
Boca Raton
State
FL
ZipCode
33487
Phone Number
1-800-593-2563
Web Address
www.naturecity.com
Pharmacist Counseling Corner

TrueHNS by NatureCity: Common Questions

Does TrueHNS by NatureCity interact with any medications?
Yes. Based on its ingredients, TrueHNS has a known interaction with 5 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
TrueHNS contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is biotin in this product safe at higher doses?
Biotin is generally well tolerated even at fairly high doses because excess is filtered out through urine. That said, high-dose supplements are worth discussing with your doctor first—normal dietary and prenatal amounts are fine on their own.
Can I take this while pregnant?
The biotin in this product is likely safe in amounts from food and prenatal vitamins. But bamboo isn't recommended during pregnancy because there isn't enough safety data on supplements. Talk with your doctor or pharmacist about whether this product is right for you.
Can I take this while breastfeeding?
Biotin from food and normal supplements should be fine. The safety of bamboo supplements while breastfeeding isn't known, so avoid concentrated extracts unless your doctor says it's okay.
Does this product really help prevent cavities?
The bamboo ingredient is included for dental caries, but we don't hold enough reliable evidence to say whether it works for that purpose.
What's biotin actually for?
Biotin is a B vitamin that your body needs for normal function. This product's biotin is proven effective if you have a biotin deficiency, a real but uncommon condition. It hasn't shown benefit for multiple sclerosis or seborrheic dermatitis.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if TrueHNS is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

TrueHNS label
Go deeper

The Full Monographs Behind TrueHNS’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bamboo

Interacts with 5 drugs

Bamboo is a giant grass whose shoots are eaten as food and whose leaves and silica-rich extracts are sold as supplements, often for hair, skin, nail, and bone support. Solid human evidence f...

Read the full Bamboo monograph → Herb & supplement monograph

Biotin

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get plenty from a normal diet, and true defi...

Read the full Biotin monograph →
Sources

Sources & How We Checked

TrueHNS's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bamboo 4 references
  1. Chandra AK, Ghosh D, Mukhopadhyay S, et al. Effect of bamboo shoot, Bambusa arundinacea (Retz.) Willd. on thyroid status under conditions of varying iodine intake in rats. Indian J Exp Biol 2004;42(8):781-786.
  2. Kitajima T. Contact allergy caused by bamboo shoots. Contact Dermatitis 1986;15(2):100-102. PubMed
  3. Sang-A-Gad P, Guharat S, Wananukul W. A mass cyanide poisoning from pickling bamboo shoots. Clin Toxicol (Phila). 2011 Nov;49(9):834-9. PubMed
  4. Satya S, Bal LM, Singhal P, Naik SN. Bamboo shoot processing: food quality and safety aspect (a review). Trends in Food Sci. Technol. 2010;21(4):181-9. DOI

See these in context on the Bamboo monograph →

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team