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Dietary supplement

Superior Omega-3 Krill Oil Ultra Concentrate 750 mg Ingredients & Drug Interactions

by Schiff MegaRed

Superior Omega-3 Krill Oil Ultra Concentrate 750 mg label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Superior Omega-3 Krill Oil Ultra Concentrate 750 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Superior Omega-3 Krill Oil Ultra Concentrate 750 mg is a dietary supplement by Schiff MegaRed with 1 active ingredient. Its ingredients are commonly taken for heart and cholesterol support, high triglycerides, joint pain and inflammation.Based on those ingredients, 838 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Krill Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Superior Omega-3 Krill Oil Ultra Concentrate 750 mg by Schiff MegaRed

Ask about any prescription or over-the-counter medication and we check it for interactions with Superior Omega-3 Krill Oil Ultra Concentrate 750 mg by Schiff MegaRed — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Superior Omega-3 Krill Oil Ultra Concentrate 750 mg by Schiff MegaRed

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 2 of its 4 active ingredients.
  • “Krill Oil” is listed as a grouped ingredient — the label gives one combined amount (750 mg) without saying how much of each component you get.
  • “Total Omega-3 Fatty Acids” is listed as a grouped ingredient — the label gives one combined amount (225 mg) without saying how much of each component you get.
  • “Total EPA and DHA” is listed as a grouped ingredient — the label gives one combined amount (183 mg) without saying how much of each component you get.

This softgel delivers krill oil and its active omega-3 fatty acids (EPA and DHA), which are the compounds your body uses from seafood-based supplements. The product also contains astaxanthin, a natural pigment from krill that gives it a reddish color.

It has 4 active ingredients total. The softgel itself is made from gelatin, glycerin, water, ethyl vanillin (for flavor), sorbitol, and sulfur dioxide as inactive ingredients.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Heart and cholesterol support.
  • We looked for evidence on: Cardiovascular disease (CVD), Hyperlipidemia, Hypertriglyceridemia, Hypertension, Heart failure, Stroke — and 2 related terms.
  • The closest evidence on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Heart failure (Natural Medicines).
  • Also on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Hyperlipidemia, Hypertension, Stroke.

The data we hold on astaxanthin — one of the active components — shows insufficient evidence to rate its effectiveness for age-related cognitive decline, macular degeneration, skin aging, Alzheimer's disease, athletic performance, or carpal tunnel syndrome. The omega-3 fatty acids (EPA and DHA) from krill are well-studied in general, but effectiveness information specific to this product isn't included in the facts we have on file.

The evidence, ingredient by ingredient Krill Oil Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects are abdominal pain, diarrhea, and red-colored stools — the latter is harmless and related to the pigment itself.

A small number of people taking doses around 6 mg reported increased bowel movements and red stools, while rare cases at higher doses (40 mg) involved severe stomach pain. There isn't enough safety data to know whether this product is safe during pregnancy or breastfeeding — talk with your doctor or pharmacist for personalized advice if you're pregnant, planning pregnancy, or nursing.

Side effects, ingredient by ingredient Krill Oil Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check whether you're on any medications broken down by your liver's CYP3A4 or CYP2B6 enzymes — astaxanthin may lower their levels. This is a theoretical risk seen in lab work but not yet confirmed in humans.

Your doctor or pharmacist can tell you if your medications fall into these categories and whether it's safe to combine them with this supplement.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is an omega-3 supplement for people looking to add krill-based EPA and DHA to their routine. If you take medications metabolized by your liver — especially statins, blood pressure drugs, or immunosuppressants — check with your doctor or pharmacist before starting, because astaxanthin may affect how your body processes them.

Expect possible mild digestive changes and harmless red stools. It's worth a conversation with your own healthcare provider if you're unsure whether it fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Superior Omega-3 Krill Oil Ultra Concentrate 750 mg, straight from the product label.

Brand Schiff MegaRed
Barcode (UPC) 020525951861
Net contents 40 Softgel(s)
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 241053
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Superior Omega-3 Krill Oil Ultra Concentrate 750 mg by Schiff MegaRed, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
020525951861
IngredientAmount% DV
Calories10 Calorie(s)--
Krill Oil750 mg--
Eicosapentaenoic Acid0 NP--
Docosahexaenoic Acid0 NP--
Total Fat1 Gram(s)1%
Total Omega-3 Fatty Acids225 mg--
Phospholipids390 mg--
Astaxanthin60 mcg--
Total EPA and DHA183 mg--

Other ingredients: Gelatin, Glycerin, Water, Ethyl Vanillin, Sorbitol, Sulfur Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Eco-Friendly. Krill is one of earth’s most abundant and sustainable organisms. The harvest of krill is well below conservative international catch guidelines. MegaRed goes a step further by only sourcing krill from the Antarctic where krill is most abundant. This helps the ecosystem maintain a healthy, sustainable krill population.

This product comes from a fishery that has been independently certified to the MSC’s standard for a well-managed and sustainable fishery. www.msc.org Schiff Sure Dissolve softgels are formulated to disintegrate within one hour.

Guaranteed: No added salt (sodium chloride), yeast, wheat or milk. No artificial colors.

Schiff Quality Guarantee Guaranteed for purity, freshness and labeled potency.

Supports three markers of cardiovascular health

Seals/Symbols

MSC-C-52013 Certified Sustainable Seafood MSC www.msc.org

Brand IP Statement(s)

Superba Boost is a trademark of the Aker Group.

2019 RB Health rb Health Hygiene Home Patents: www. rb.com/patents

General Statements

Join, earn points & get rewards MegaRed rewards www.megaredrewards.com See cap sticker for details Valid for US residents only. Schiff since 1936 Easily absorbed

Formula

35% more Omega-3s Than standard krill oil

Gelatin is derived from bovine sources. More Omega-3s per MG MegaRed is the first to give you 35% more Omega-3s per milligram compared to what you can find in standard krill oil supplements. All in just one, easy to swallow softgel. Purity MegaRed with PureTech is 3X more pure than standard krill oil, with the removal of salts and other impurities providing the purest krill oil on the market. You can see the difference with a lighter more translucent softgel. Absorption MegaRed is easily recognized and utilized by your body's cell membranes, which are also phospholipid, allowing easy absorption. Just one MegaRed softgel provides an unique combination of Omega-3 fatty acids and the powerful antioxidant astaxanthin to support your health.

MegaRed Superior Omega-3 Krill Oil Ultra Concentrate contains ingredients that support three markers of cardiovascular health: Omega-3 index: The amount of omega-3 fatty acids, EPA and DHA in blood cells Triglycerides: A type of fat measured in the blood C-Reactive Protein (CRP): An important marker of systemic inflammation More Omega-3s in one softgel One 750 mg MegaRed Ultra Concentrate Softgel Two 500 mg Standard Pure Krill Oil Softgels

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take one (1) softgel daily. Consult your healthcare professional for the proper amount for you.

Precautions

Contains shellfish (krill). This product contains sulfites.

Caution: If you are pregnant, breastfeeding, allergic to seafood, have existing medical conditions, taking medications (including blood thinners) or are planning a medical or surgical procedure, consult a healthcare professional before use.

Caution: If you are pregnant, breastfeeding, allergic to seafood, have existing medical conditions, taking medications (including blood thinners) or are planning a medical or surgical procedure, consult a healthcare professional before use.

Keep out of reach of children.

Protected with a tamper evident seal. Do not use if seal under cap is broken or missing.

Storage

Store in a cool, dry place with lid tightly closed. Do not remove freshness pack from bottle.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Superior Omega-3 Krill Oil Ultra Concentrate 750 mg by Schiff MegaRed label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Superior Omega-3 Krill Oil Ultra Concentrate 750 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Superior Omega-3 Krill Oil Ultra Concentrate 750 mg by Schiff MegaRed

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Krill Oil

Interacts with
208 drugs
750 mg per serving

Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglyce...

Krill Oil monograph & interactions
  • › Total Omega-3 Fatty Acids
  • › Phospholipids
  • › Astaxanthin

Other (inactive) ingredients: Gelatin, Glycerin, Water, Ethyl Vanillin, Sorbitol, Sulfur Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Superior Omega-3 Krill Oil Ultra Concentrate 750 mg by Schiff MegaRed Drug Interactions

Want to check YOUR meds against Superior Omega-3 Krill Oil Ultra Concentrate 750 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
838Drugs
838 Moderate

Ingredients driving the most interactions

Krill Oil 208

Individual Drug Interactions

The ingredients in Superior Omega-3 Krill Oil Ultra Concentrate 750 mg interact with 838 drugs. Click any drug to see the details.

1 of the 1 ingredient in Superior Omega-3 Krill Oil Ultra Concentrate 750 mg interact with drugs. Each result below shows which ingredient is responsible. Krill Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Superior Omega-3 Krill Oil Ultra Concentrate 750 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Krill Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, krill oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Taking high doses of omega-3 fatty acids from fish oil can modestly decrease platelet aggregation. Since krill oil also contains these fatty acids, taking high doses of krill oil might also inhibit platelet aggregation. Theoretically, taking high doses of krill oil with antiplatelet or anticoagulant drugs might increase the risk of bleeding. However, the omega-3 content of krill oil is much lower than that of fish oil.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking krill oil with antidiabetes drugs might increase the risk of hypoglycemia.
Some research in animals and humans shows that krill oil might lower blood glucose levels. However, a small study shows that taking krill oil does not reduce blood glucose levels in patients with type 2 diabetes, most of whom were taking antidiabetes drugs.

Likelihood Possible Evidence B
Krill Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Superior Omega-3 Krill Oil Ultra Concentrate 750 mg, from the product label.

Schiff MegaRed

See all Schiff MegaRed products
Name
RB Health (US) LLC
City
Parsippany
State
NJ
ZipCode
07054-0224
Phone Number
1-800-526-6251
Web Address
www.megared.com
Pharmacist Counseling Corner

Superior Omega-3 Krill Oil Ultra Concentrate 750 mg by Schiff MegaRed: Common Questions

Does Superior Omega-3 Krill Oil Ultra Concentrate 750 mg by Schiff MegaRed interact with any medications?
Yes. Based on its ingredients, Superior Omega-3 Krill Oil Ultra Concentrate 750 mg has a known interaction with 838 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Superior Omega-3 Krill Oil Ultra Concentrate 750 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are EPA and DHA, and why are they in krill oil?
EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are omega-3 fatty acids that krill naturally contain. They're the compounds your body actually uses from seafood-based supplements, so companies include them to show you what you're getting in each dose.
Will this product turn my stools red?
Yes — red or reddish stools are possible because of astaxanthin, the natural pigment in krill. It's harmless and expected; the color comes from the supplement itself, not a sign of bleeding or a problem.
Is astaxanthin safe to take during pregnancy or while breastfeeding?
There isn't enough safety data to know either way. The safety information we have advises against it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist to get personalized advice for your situation.
What does the astaxanthin in this product do?
We don't have reliable evidence in our data that astaxanthin works for the conditions it's often marketed for — like age-related cognitive decline, macular degeneration, or skin aging. More research is needed.
Does this product have a lot of fillers or other ingredients I don't need?
The softgel capsule itself is made from gelatin, glycerin, water, and a few other inactive ingredients to hold and flavor it. That's typical for a softgel — they're not fillers in the sense of padding; they're part of how the supplement is delivered.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Superior Omega-3 Krill Oil Ultra Concentrate 750 mg label
Go deeper

The Full Monographs Behind Superior Omega-3 Krill Oil Ultra Concentrate 750 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Krill Oil

Interacts with 208 drugs

Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglycerides and supporting heart health, but t...

Read the full Krill Oil monograph → Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Superior Omega-3 Krill Oil Ultra Concentrate 750 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Krill Oil 13 references
  1. Leaf A. On the reanalysis of the GISSI-Prevenzione. Circulation 2002;105:1874-5. PubMed
  2. Connor WE. n-3 Fatty acids from fish and fish oil: panacea or nostrum? Am J Clin Nutr 2001;74;415-6. PubMed
  3. Calder PC. N-3 polyunsaturated fatty acids, inflammation and immunity: pouring oil on troubled waters or another fishy tale? Nutr Res 2001;21:309-41. DOI
  4. Bunea R, El Farrah K, Deutsch L. Evaluation of the effects of Neptune Krill Oil on the clinical course of hyperlipidemia. Altern Med Rev 2004;9:420-8.
  5. Sampalis F, Bunea R, Pelland MF, et al. Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea. Altern Med Rev 2003;8:171-9.
  6. Harris WS, Miller M, Tighe AP, et al. Omega-3 fatty acids and coronary heart disease risk: clinical and mechanistic perspectives. Atherosclerosis 2008;197:12-24. PubMed
  7. Tandy S, Chung RW, Wat E, et al. Dietary krill oil supplementation reduces hepatic steatosis, glycemia, and hypercholesterolemia in high-fat-fed mice. J Agric Food Chem 10-14-2009;57:9339-45. PubMed
  8. Maki, K. C., Reeves, M. S., Farmer, M., Griinari, M., Berge, K., Vik, H., Hubacher, R., and Rains, T. M. Krill oil supplementation increases plasma concentrations of eicosapentaenoic and docosahexaenoic acids in overweight and obese men and women. Nutr.R PubMed
  9. Albert BB, Derraik JG, Brennan CM, et al. Supplementation with a blend of krill and salmon oil is associated with increased metabolic risk in overweight men. Am J Clin Nutr 2015;102(1):49-57.
  10. Berge K, Musa-Veloso K, Harwood M, Hoem N, Burri L. Krill oil supplementation lowers serum triglycerides without increasing low-density lipoprotein cholesterol in adults with borderline high or high triglyceride levels. Nutr Res 2014;34(2):126-33. PubMed
  11. Lobraico JM, DiLello LC, Butler AD, Cordisco ME, Petrini JR, Ahmadi R. Effects of krill oil on endothelial function and other cardiovascular risk factors in participants with type 2 diabetes, a randomized controlled trial. BMJ Open Diabetes Res Care. 2015 PubMed
  12. van der Wurff ISM, von Schacky C, Bergeland T, Zeegers MP, Kirschner PA, de Groot RHM. Krill oil supplementation's effect on school grades in typically developing adolescents. Prostaglandins Leukot Essent Fatty Acids 2023;191:102553. PubMed
  13. van der Wurff ISM, von Schacky C, Bergeland T, et al. Effect of 1 year krill oil supplementation on cognitive achievement of Dutch adolescents: A double-blind randomized controlled trial. Nutrients. 2019;11(6):1230. PubMed

See these in context on the Krill Oil monograph →

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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