UriCare Ingredients & Drug Interactions
by Himalaya
What is this page for?
First and foremost: checking UriCare against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
UriCare is a dietary supplement by Himalaya with 16 active ingredients. Its ingredients are commonly taken for nausea and vomiting, digestive upset, gas, and diarrhea, calming or sedative effect.Based on those ingredients, 460 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cyperus, Didymocarpus extract, Shilajeet. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against UriCare by Himalaya
Ask about any prescription or over-the-counter medication and we check it for interactions with UriCare by Himalaya — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of UriCare by Himalaya
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
UriCare contains 16 ingredients, including a proprietary herbal extract blend. The active botanicals include shilajit (in two forms), didymocarpus extract, winter begonia, prickly chaff flower, little ironweed, Indian madder, onosma bracteatum, and cyperus.
The product also contains one inactive ingredient, plant-based cellulose.
Does it work?
Not established
The evidence we have on file for the ingredients in UriCare does not establish their effectiveness. Both shilajit and didymocarpus extract (linked to astragalus monograph data) are rated as having insufficient reliable evidence for the conditions they're traditionally used for — meaning we don't have enough quality research to know whether they work.
How safe is it?
Well-documented data
Shilajit carries several safety cautions. Only use purified, tested brands, because unpurified products may contain heavy metals or other contaminants.
Rare side effects include headache and, in isolated cases, severe allergic reactions including anaphylaxis and hives (especially with doses above 400 mg or after exercise). There's also a case report of high blood pressure linked to shilajit during pregnancy, though a direct cause wasn't confirmed.
Didymocarpus extract (astragalus) is generally well tolerated short-term in healthy adults, though long-term human safety data is limited. Reported side effects are uncommon and include dizziness, rash, and eczema.
Meds to double-check
Moderate interaction found
Check your medications with the tool below if you take antidiabetes drugs (risk of low blood sugar), immunosuppressants, lithium, or cyclophosphamide — these have documented Moderate interactions with ingredients in this product.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
If you take antidiabetes medications, immunosuppressants, lithium, or cyclophosphamide, check with your pharmacist before starting UriCare — the interactions are real and could affect how your drugs work. For everyone else, the main caution is using a purified, tested brand and being aware that the ingredients lack strong evidence of effectiveness.
Talk to your pharmacist about whether this supplement makes sense for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 16 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 20, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about UriCare, straight from the product label.
| Brand | Himalaya |
|---|---|
| Barcode (UPC) | 605069002110 |
| Net contents | 240 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Nov 20, 2017 |
| DSLD ID | 80244 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for UriCare by Himalaya, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Herbal Extract Blend | 840 mg | -- |
| Cyperus | 0 NP | -- |
| Cyperus extract | 0 NP | -- |
| Shilajeet | 0 NP | -- |
| Shilajeet extract | 0 NP | -- |
| Didymocarpus | 0 NP | -- |
| Winter Begonia | 0 NP | -- |
| Prickly Chaff flower | 0 NP | -- |
| Little Ironweed | 0 NP | -- |
| Didymocarpus extract | 0 NP | -- |
| Onosma bracteatum | 0 NP | -- |
| Winter Begonia extract | 0 NP | -- |
| Indian Madder | 0 NP | -- |
| Indian Madder extract | 0 NP | -- |
| Prickly Chaff flower extract | 0 NP | -- |
| Onosma extract | 0 NP | -- |
| Little Ironweed extract | 0 NP | -- |
Other ingredients: Plant Based Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
The kidneys play a major part in regulating fluid balance but also have a significant role in detox and balancing blood minerals like sodium and calcium. Several techniques and herbal applications, originally outlined by Ayurveda, are only now being understood by science.
cGMP
Happiness through wellness
Crafting traditional medicines based on Ayurveda, a 5,000 year old science that believes the journey back to wholeness begins with nurturing the capacity for joy.
Trusting the gifts of nature and the irreplaceable relationship between the plant and its native soil for consistent healing properties.
Contributing to the wellness of the earth by teaching our family of farmers to grow native plants sustainably on their land and reduce the demand on the local environment.
Building communities by advocating women in farming, protecting fair prices, providing maternal health, sponsoring clinical services and offering school wellness programs.
Believing that if wellness is the path to happiness, we must contribute to the wellness of all things. Wellness of people, wellness of the environment, wellness of our communities.
Family owned for more than 85 years
Since 1930
For normal urine flow & release Supports kidney & bladder performace
Happiness through wellness
2 Month supply
Mfg. Lic. No. AUS-83
Product of India
Questions? Please call 1-800-869-4640 or visit www.himalayausa.com
Formula
Shilajeet and Cyperus are among the ingredients included in UriCare, which tone and comfort the urinary tract, kidneys and bladder to promote ease of flow.
Featured herbs on front: Shilajeet (pitch), Little Ironweed (aerial parts) & Cyperus (aerial parts)
Brand IP Statement(s)
Shilajeet and Cyperus are among the ingredients included in UriCare, which tone and comfort the urinary tract, kidneys and bladder to promote ease of flow.
Formulation
Gluten free
Vegan friendly
Wheat, corn, soy, dairy
No ingredients of animal origin
Non-GMO Gluten free
General
HUS-5033395
Seals/Symbols
Non GMO Project Verified nongmoproject.org
FDA Statement of Identity
Herbal Supplement
Suggested/Recommended/Usage/Directions
Recommended Use: Adults take 2 capsules twice daily with meals.
Precautions
Caution: As with any supplement, consult a healthcare practitioner before use if you are pregnant, nursing, taking medication, have a medical condition or are planning any medical procedure.
Discontinue use and consult a healthcare practitioner if any adverse reactions occur.
Keep out of reach of children.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
UriCare by Himalaya label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in UriCare by Himalaya
These are the 16 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Herbal Extract Blend
- › Cyperus
- › Cyperus extract
- › Shilajeet
- › Shilajeet extract
- › Didymocarpus
- › Winter Begonia
- › Prickly Chaff flower
- › Little Ironweed
- › Didymocarpus extract
- › Onosma bracteatum
- › Winter Begonia extract
- › Indian Madder
- › Indian Madder extract
- › Prickly Chaff flower extract
- › Onosma extract
- › Little Ironweed extract
Other (inactive) ingredients: Plant Based Cellulose. These complete the product’s ingredient list but are not active constituents.
UriCare by Himalaya Drug Interactions
HelloPharmacist Interaction Report
UriCare by Himalaya contains ingredients that interact with medications.
The most serious concern is shilajit (present as both Shilajeet and Shilajeet extract), which can increase the risk of low blood sugar (hypoglycemia) when combined with diabetes medications — this is a Moderate severity interaction. Another ingredient, didymocarpus extract, has been linked to interactions with immunosuppressant drugs, lithium, cyclophosphamide, and antidiabetes drugs, all rated Moderate severity.
The immunosuppressant interaction is particularly important if you're taking drugs to prevent organ rejection or manage autoimmune conditions, as this ingredient may reduce their effectiveness. With lithium, there's a theoretical risk of increased lithium levels and side effects due to a diuretic effect.
We were unable to check several other ingredients in this formula — cyperus, winter begonia, prickly chaff flower, little ironweed, onosma bracteatum, Indian madder, and their extracts — because we don't have interaction data on file for them.
Read the full breakdown — every affected drug type, severity by severity
Altogether, these interactions span 203 individual medications. Before you start UriCare, run your exact medications through the interaction checker on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against UriCare?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in UriCare interact with 460 drugs. Click any drug to see the details.
3 of the 16 ingredients in UriCare interact with drugs. Each result below shows which ingredient is responsible. Cyperus Didymocarpus extract Shilajeet
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Didymocarpus ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Didymocarpus Extract + 6-mercaptopurine interactionAbrocitinibCibinqo
How Abrocitinib interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Didymocarpus ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Didymocarpus Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with UriCare — through 2 ingredients. Tap an ingredient for the detail:
Didymocarpus ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Didymocarpus Extract + Acarbose interactionShilajeet ExtractAntidiabetes Drugs Moderate
Interaction Summary
Taking shilajit with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Shilajeet Extract + Acarbose interactionAcepromazineAtravet
How Acepromazine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acepromazine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractBarbiturates Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental increases total sleep time three-fold compared to the effects of sodium thiopental alone.
Read the full Cyperus Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractBarbiturates Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental increases total sleep time three-fold compared to the effects of sodium thiopental alone.
Read the full Cyperus Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractBarbiturates, Cns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental increases total sleep time three-fold compared to the effects of sodium thiopental alone.
Read the full Cyperus Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, Dichloralantipyrine, IsomethepteneAmidrine, Midchlor, Migquin, Migratine
How Acetaminophen, Dichloralantipyrine, Isometheptene interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Dichloralantipyrine, Isometheptene interactionAcetaminophen, Dichloralphenazone, IsomethepteneMidrin
How Acetaminophen, Dichloralphenazone, Isometheptene interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Dichloralphenazone, Isometheptene interactionAcetaminophen, Dichlorophenazone, IsometheptaneIsocom
How Acetaminophen, Dichlorophenazone, Isometheptane interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Dichlorophenazone, Isometheptane interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Hydrocodone interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Meperidine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Oxycodone interactionAcetaminophen, PentazocineTalacen
How Acetaminophen, Pentazocine interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Pentazocine interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetaminophen, Propoxyphene interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with UriCare — through 1 ingredient. Tap an ingredient for the detail:
Cyperus ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Extract + Acetazolamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in UriCare with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Cyperus
Barbiturates
Animal research suggests that taking adrue in combination with sodium thiopental increases total sleep time three-fold compared to the effects of sodium thiopental alone. Theoretically, concomitant use of adrue and barbiturates might increase the risk of drowsiness and motor reflex depression. Some barbiturates include amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), and others.
Benzodiazepines
Animal research suggests that taking adrue in combination with diazepam increases total sleep time four-fold compared to the effects of diazepam alone. Theoretically, concomitant use adrue and benzodiazepines might increase the risk of drowsiness and motor reflex depression. Some benzodiazepines include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others.
Cns Depressants
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone. Theoretically, concomitant use of adrue with CNS depressants might cause additive sedation. Some CNS depressants include benzodiazepines, such as diazepam (Valium), alprazolam (Xanax), triazolam (Halcion), and estazolam (ProSom); barbiturates, such as mephobarbital (Mebaral), phenobarbital (Luminal Sodium), and pentobarbital sodium (Nembutal); zolpidem (Ambien); and others.
Didymocarpus extract
Antidiabetes Drugs
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.
Cyclophosphamide
Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.
Immunosuppressants
Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.
Lithium
Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.
Shilajeet
Antidiabetes Drugs
Taking shilajit with antidiabetes drugs might increase the risk of hypoglycemia.
Most human and animal research shows that shilajit can decrease fasting plasma glucose levels. In an animal model, shilajit 100 mg per kg daily enhanced the glucose-lowering ability of both glibenclamide and metformin when given in combination over a 4 week period. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Brand information
Manufacturer and brand details for UriCare, from the product label.
Himalaya
See all Himalaya products- Name
- The Himalaya Drug Company
- City
- Makali
- State
- Bangalore
- ZipCode
- 562 162
UriCare by Himalaya: Common Questions
Does UriCare by Himalaya interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is it safe to take UriCare during pregnancy?
Can I take UriCare while breastfeeding?
What is shilajit and what does it do?
Does UriCare actually work?
Are there any fillers or other ingredients I should know about?
Could shilajit cause an allergic reaction?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if UriCare is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind UriCare’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Adrue
Interacts with 256 drugsAdrue (Cyperus articulatus) is a sedge whose rhizome has long been used in traditional medicine for nausea and other stomach complaints, and as a mild calming agent. Solid human studies are...
Read the full Adrue monograph → Herb & supplement monographShilajit
Interacts with 86 drugsShilajit is a sticky, tar-like substance found in rocks of mountain ranges like the Himalayas, used in traditional Ayurvedic medicine for energy and vitality. Human evidence is limited and m...
Read the full Shilajit monograph → Herb & supplement monographAstragalus
Interacts with 208 drugsAstragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...
Read the full Astragalus monograph →Sources & How We Checked
UriCare's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 22 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Adrue 1 reference
- Rakotonirina, V. S., Bum, E. N., Rakotonirina, A., and Bopelet, M. Sedative properties of the decoction of the rhizome of Cyperus articulatus. Fitoterapia 2001;72(1):22-29. PubMed
Shilajit 8 references
- Sadeghi SMH, Hosseini Khameneh SM, Khodadoost M, et al. Efficacy of momiai in tibia fracture repair: A randomized double-blinded placebo-controlled clinical trial. J Altern Complement Med 2020;26(6):521-528.
- Losa F, Deidda M, Firinu D, Martino MLD, Barca MP, Giacco SD. Exercise-induced anaphylaxis with an Ayurvedic drug as cofactor: A case report. World J Clin Cases 2019;7(5):623-627. PubMed
- Biswas TK, Pandit S, Mondal S, et al. Clinical evaluation of spermatogenic activity of processed Shilajit in oligospermia. Andrologia 2010;42(1):48-56. PubMed
- Stavropoulos K, Sotiriadis A, Patoulias D, et al. Pseudohyperaldosteronism due to mumijo consumption during pregnancy: a licorice-like syndrome. Gynecol Endocrinol 2018;34(12):1019-1021. PubMed
- Ghezelbash B, Shahrokhi N, Khaksari M, Ghaderi-Pakdel F, Asadikaram G. Hepatoprotective effects of shilajit on high fat-diet induced non-alcoholic fatty liver disease (NAFLD) in rats. Horm Mol Biol Clin Investig 2020;41(1):/j/hmbci. PubMed
- Ghezelbash B, Shahrokhi N, Khaksari M, Asadikaram G, Shahrokhi M, Shirazpour S. Protective roles of shilajit in modulating resistin, adiponectin, and cytokines in rats with non-alcoholic fatty liver disease. Chin J Integr Med 2022;28(6):531-537. PubMed
- Jafari M, Forootanfar H, Ameri A, et al. Antioxidant, cytotoxic and hyperalgesia-suppressing activity of a native Shilajit obtained from Bahr Aseman mountains. Pak J Pharm Sci 2019;32(5):2167-2173. DOI
- Trivedi NA, Mazumdar B, Bhatt JD, Hemavathi KG. Effect of shilajit on blood glucose and lipid profile in alloxan-induced diabetic rats. Ind. J. Pharmacol. 2004; 36(6):373-376.
Astragalus 13 references
- Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
- Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
- Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
- Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
- Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
- Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
- Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
- Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
- Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
- Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
- Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
- Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
- Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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