Interactions on record — worth a quick check against your medications. Based on 3 of 16 ingredients. Check your meds →
Dietary supplement

UriCare Ingredients & Drug Interactions

by Himalaya

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

UriCare is a dietary supplement by Himalaya with 16 active ingredients. Its ingredients are commonly taken for nausea and vomiting, digestive upset, gas, and diarrhea, calming or sedative effect.Based on those ingredients, 460 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cyperus, Didymocarpus extract, Shilajeet. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of UriCare by Himalaya

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 16 active ingredients.
  • “Proprietary Herbal Extract Blend” is a proprietary blend — the label gives one combined amount (840 mg) without saying how much of each component you get.

UriCare contains 16 ingredients, including a proprietary herbal extract blend. The active botanicals include shilajit (in two forms), didymocarpus extract, winter begonia, prickly chaff flower, little ironweed, Indian madder, onosma bracteatum, and cyperus.

The product also contains one inactive ingredient, plant-based cellulose.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: tone and comfort urinary tract kidney and bladder.
  • We looked for evidence on: Urinary Tract Infections (UTIs), Chronic kidney disease (CKD), Diabetic nephropathy, IgA nephropathy, Membranous nephropathy, Nephrotic syndrome — and 4 related terms.
  • The closest evidence on file: Astragalus is rated "Insufficient Reliable Evidence To Rate" for Diabetic nephropathy (Natural Medicines).
  • Also on file: Astragalus is rated "Insufficient Reliable Evidence To Rate" for Nephrotic syndrome, Urinary Tract Infections (UTIs), IgA nephropathy, Chronic kidney disease (CKD), and more.

The evidence we have on file for the ingredients in UriCare does not establish their effectiveness. Both shilajit and didymocarpus extract (linked to astragalus monograph data) are rated as having insufficient reliable evidence for the conditions they're traditionally used for — meaning we don't have enough quality research to know whether they work.

The evidence, ingredient by ingredient Adrue Shilajit Astragalus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Shilajit carries several safety cautions. Only use purified, tested brands, because unpurified products may contain heavy metals or other contaminants.

Rare side effects include headache and, in isolated cases, severe allergic reactions including anaphylaxis and hives (especially with doses above 400 mg or after exercise). There's also a case report of high blood pressure linked to shilajit during pregnancy, though a direct cause wasn't confirmed.

Didymocarpus extract (astragalus) is generally well tolerated short-term in healthy adults, though long-term human safety data is limited. Reported side effects are uncommon and include dizziness, rash, and eczema.

Side effects, ingredient by ingredient Adrue Shilajit Astragalus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Adrue, Astragalus, Shilajit.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 460 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications with the tool below if you take antidiabetes drugs (risk of low blood sugar), immunosuppressants, lithium, or cyclophosphamide — these have documented Moderate interactions with ingredients in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you take antidiabetes medications, immunosuppressants, lithium, or cyclophosphamide, check with your pharmacist before starting UriCare — the interactions are real and could affect how your drugs work. For everyone else, the main caution is using a purified, tested brand and being aware that the ingredients lack strong evidence of effectiveness.

Talk to your pharmacist about whether this supplement makes sense for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 16 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 20, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about UriCare, straight from the product label.

Brand Himalaya
Barcode (UPC) 605069002110
Net contents 240 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Nov 20, 2017
DSLD ID 80244
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for UriCare by Himalaya, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
120
UPC/BARCODE
605069002110
IngredientAmount% DV
Proprietary Herbal Extract Blend840 mg--
Cyperus0 NP--
Cyperus extract0 NP--
Shilajeet0 NP--
Shilajeet extract0 NP--
Didymocarpus0 NP--
Winter Begonia0 NP--
Prickly Chaff flower0 NP--
Little Ironweed0 NP--
Didymocarpus extract0 NP--
Onosma bracteatum0 NP--
Winter Begonia extract0 NP--
Indian Madder0 NP--
Indian Madder extract0 NP--
Prickly Chaff flower extract0 NP--
Onosma extract0 NP--
Little Ironweed extract0 NP--

Other ingredients: Plant Based Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

The kidneys play a major part in regulating fluid balance but also have a significant role in detox and balancing blood minerals like sodium and calcium. Several techniques and herbal applications, originally outlined by Ayurveda, are only now being understood by science.

cGMP

Happiness through wellness

Crafting traditional medicines based on Ayurveda, a 5,000 year old science that believes the journey back to wholeness begins with nurturing the capacity for joy.

Trusting the gifts of nature and the irreplaceable relationship between the plant and its native soil for consistent healing properties.

Contributing to the wellness of the earth by teaching our family of farmers to grow native plants sustainably on their land and reduce the demand on the local environment.

Building communities by advocating women in farming, protecting fair prices, providing maternal health, sponsoring clinical services and offering school wellness programs.

Believing that if wellness is the path to happiness, we must contribute to the wellness of all things. Wellness of people, wellness of the environment, wellness of our communities.

Family owned for more than 85 years

Since 1930

For normal urine flow & release Supports kidney & bladder performace

Happiness through wellness

2 Month supply

Mfg. Lic. No. AUS-83

Product of India

Questions? Please call 1-800-869-4640 or visit www.himalayausa.com

Formula

Shilajeet and Cyperus are among the ingredients included in UriCare, which tone and comfort the urinary tract, kidneys and bladder to promote ease of flow.

Featured herbs on front: Shilajeet (pitch), Little Ironweed (aerial parts) & Cyperus (aerial parts)

Brand IP Statement(s)

Shilajeet and Cyperus are among the ingredients included in UriCare, which tone and comfort the urinary tract, kidneys and bladder to promote ease of flow.

Formulation

Gluten free

Vegan friendly

Wheat, corn, soy, dairy

No ingredients of animal origin

Non-GMO Gluten free

General

HUS-5033395

Seals/Symbols

Non GMO Project Verified nongmoproject.org

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Recommended Use: Adults take 2 capsules twice daily with meals.

Precautions

Caution: As with any supplement, consult a healthcare practitioner before use if you are pregnant, nursing, taking medication, have a medical condition or are planning any medical procedure.

Discontinue use and consult a healthcare practitioner if any adverse reactions occur.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

UriCare by Himalaya label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in UriCare by Himalaya

These are the 16 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Herbal Extract Blend

840 mg per serving
  • Cyperus
  • Cyperus extract
  • Shilajeet
  • Shilajeet extract
  • › Didymocarpus
  • › Winter Begonia
  • › Prickly Chaff flower
  • › Little Ironweed
  • Didymocarpus extract
  • › Onosma bracteatum
  • › Winter Begonia extract
  • › Indian Madder
  • › Indian Madder extract
  • › Prickly Chaff flower extract
  • › Onosma extract
  • › Little Ironweed extract

Other (inactive) ingredients: Plant Based Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

UriCare by Himalaya Drug Interactions

Want to check YOUR meds against UriCare?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
460Drugs
460 Moderate

Ingredients driving the most interactions

Cyperus 256

Each ingredient & the kinds of drugs it affects

For each ingredient in UriCare with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Cyperus3 drug types · 256 drugs

Barbiturates

Animal research suggests that taking adrue in combination with sodium thiopental increases total sleep time three-fold compared to the effects of sodium thiopental alone. Theoretically, concomitant use of adrue and barbiturates might increase the risk of drowsiness and motor reflex depression. Some barbiturates include amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), and others.

Likelihood Possible Evidence D
Benzodiazepines

Animal research suggests that taking adrue in combination with diazepam increases total sleep time four-fold compared to the effects of diazepam alone. Theoretically, concomitant use adrue and benzodiazepines might increase the risk of drowsiness and motor reflex depression. Some benzodiazepines include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others.

Likelihood Possible Evidence D
Cns Depressants

Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone. Theoretically, concomitant use of adrue with CNS depressants might cause additive sedation. Some CNS depressants include benzodiazepines, such as diazepam (Valium), alprazolam (Xanax), triazolam (Halcion), and estazolam (ProSom); barbiturates, such as mephobarbital (Mebaral), phenobarbital (Luminal Sodium), and pentobarbital sodium (Nembutal); zolpidem (Ambien); and others.

Likelihood Possible Evidence D

Didymocarpus extract4 drug types · 208 drugs

Antidiabetes Drugs

Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.

Likelihood Probable Evidence A
Cyclophosphamide

Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D

Shilajeet1 drug type · 86 drugs

Antidiabetes Drugs

Taking shilajit with antidiabetes drugs might increase the risk of hypoglycemia.
Most human and animal research shows that shilajit can decrease fasting plasma glucose levels. In an animal model, shilajit 100 mg per kg daily enhanced the glucose-lowering ability of both glibenclamide and metformin when given in combination over a 4 week period. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for UriCare, from the product label.

Himalaya

See all Himalaya products
Name
The Himalaya Drug Company
City
Makali
State
Bangalore
ZipCode
562 162
Pharmacist Counseling Corner

UriCare by Himalaya: Common Questions

Does UriCare by Himalaya interact with any medications?
Yes. Based on its ingredients, UriCare has a known interaction with 460 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
UriCare contains 16 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take UriCare during pregnancy?
No. Shilajit and didymocarpus extract both have insufficient safety data for pregnancy and should be avoided. There's also a case report of high blood pressure in a pregnant woman taking shilajit. Talk to your doctor or pharmacist before considering this product if you're pregnant or planning to become pregnant.
Can I take UriCare while breastfeeding?
Safety while breastfeeding is unknown for both shilajit and didymocarpus extract, so it's best avoided. Speak with your pharmacist or doctor for personalized guidance if you're breastfeeding.
What is shilajit and what does it do?
Shilajit is a mineral-rich substance traditionally used in Ayurvedic medicine. In this product it's present in two forms. However, we don't have enough reliable evidence to say it works for any specific condition — ratings for sexual function, athletic performance, and other traditional uses are all marked insufficient evidence.
Does UriCare actually work?
The evidence we hold doesn't establish that the active ingredients in UriCare are effective. The ingredients lack sufficient reliable evidence to support their use for any specific condition.
Are there any fillers or other ingredients I should know about?
UriCare contains plant-based cellulose as an inactive ingredient. The 16 active ingredients include herbal extracts; most are part of a proprietary blend, which means their exact amounts aren't disclosed on the label.
Could shilajit cause an allergic reaction?
Yes, though it's rare. A documented case involved a woman who developed hives and then anaphylaxis (a severe whole-body allergic reaction) after taking shilajit, especially with exercise. If you have a history of allergies or if you experience hives, swelling, or difficulty breathing after taking this product, seek medical help right away.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if UriCare is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

UriCare label
Sources

Sources & How We Checked

UriCare's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Adrue 1 reference
  1. Rakotonirina, V. S., Bum, E. N., Rakotonirina, A., and Bopelet, M. Sedative properties of the decoction of the rhizome of Cyperus articulatus. Fitoterapia 2001;72(1):22-29. PubMed

See these in context on the Adrue monograph →

Shilajit 8 references
  1. Sadeghi SMH, Hosseini Khameneh SM, Khodadoost M, et al. Efficacy of momiai in tibia fracture repair: A randomized double-blinded placebo-controlled clinical trial. J Altern Complement Med 2020;26(6):521-528.
  2. Losa F, Deidda M, Firinu D, Martino MLD, Barca MP, Giacco SD. Exercise-induced anaphylaxis with an Ayurvedic drug as cofactor: A case report. World J Clin Cases 2019;7(5):623-627. PubMed
  3. Biswas TK, Pandit S, Mondal S, et al. Clinical evaluation of spermatogenic activity of processed Shilajit in oligospermia. Andrologia 2010;42(1):48-56. PubMed
  4. Stavropoulos K, Sotiriadis A, Patoulias D, et al. Pseudohyperaldosteronism due to mumijo consumption during pregnancy: a licorice-like syndrome. Gynecol Endocrinol 2018;34(12):1019-1021. PubMed
  5. Ghezelbash B, Shahrokhi N, Khaksari M, Ghaderi-Pakdel F, Asadikaram G. Hepatoprotective effects of shilajit on high fat-diet induced non-alcoholic fatty liver disease (NAFLD) in rats. Horm Mol Biol Clin Investig 2020;41(1):/j/hmbci. PubMed
  6. Ghezelbash B, Shahrokhi N, Khaksari M, Asadikaram G, Shahrokhi M, Shirazpour S. Protective roles of shilajit in modulating resistin, adiponectin, and cytokines in rats with non-alcoholic fatty liver disease. Chin J Integr Med 2022;28(6):531-537. PubMed
  7. Jafari M, Forootanfar H, Ameri A, et al. Antioxidant, cytotoxic and hyperalgesia-suppressing activity of a native Shilajit obtained from Bahr Aseman mountains. Pak J Pharm Sci 2019;32(5):2167-2173. DOI
  8. Trivedi NA, Mazumdar B, Bhatt JD, Hemavathi KG. Effect of shilajit on blood glucose and lipid profile in alloxan-induced diabetic rats. Ind. J. Pharmacol. 2004; 36(6):373-376.

See these in context on the Shilajit monograph →

Astragalus 13 references
  1. Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
  2. Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
  3. Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
  4. Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
  5. Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
  6. Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
  7. Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
  8. Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
  9. Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
  10. Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
  11. Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
  12. Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
  13. Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):

See these in context on the Astragalus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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