Interactions on record — worth a quick check against your medications. Based on 4 of 7 ingredients. Check your meds →
Dietary supplement

Varicose Health & Circulation Ingredients & Drug Interactions

by New Sun

Varicose Health & Circulation label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Varicose Health & Circulation against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Varicose Health & Circulation is a dietary supplement by New Sun with 7 active ingredients. Its ingredients are commonly taken for diarrhea, sore throat and mouth irritation, minor skin inflammation and wounds.Based on those ingredients, 362 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Butcher's Broom, Horse Chestnut, Rutin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Varicose Health & Circulation by New Sun

Ask about any prescription or over-the-counter medication and we check it for interactions with Varicose Health & Circulation by New Sun — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Varicose Health & Circulation by New Sun

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 7 active ingredients.

Varicose Health & Circulation has 7 ingredients total. The active ones are white oak, butcher's broom, horse chestnut (listed twice, as both a standard form and a seed concentrate), rutin, and a proprietary blend.

White oak is traditionally used short-term for circulation support. Butcher's broom and horse chestnut are the primary herbs in circulation formulas — butcher's broom is thought to work on veins and tissues, while horse chestnut seed extract (with toxic parts removed) is studied for chronic venous insufficiency.

Rutin is a plant compound with antioxidant properties. The product also contains inactive ingredients including gelatin, rice flour, magnesium stearate, and silica, which serve as capsule material, filler, and flow agents.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: helps support healthy circulation.
  • We looked for evidence on: Chronic venous insufficiency (CVI), Varicose veins, Hemorrhoids, Lymphedema, Postoperative swelling, leg swelling — and 2 related terms.
  • The strongest evidence on file: Butcher's Broom is rated "Possibly Effective" for Chronic venous insufficiency (CVI) (Natural Medicines).
  • Also on file: Horse Chestnut is rated "Possibly Effective" for Chronic venous insufficiency (CVI).
  • Also on file: Rutin is rated "Insufficient Reliable Evidence To Rate" for Hemorrhoids, Lymphedema, Varicose veins, Postoperative swelling.

The evidence for this product's ingredients is mixed. Butcher's broom and horse chestnut are both rated possibly effective for chronic venous insufficiency — the condition where veins have trouble returning blood to your heart — based on available studies.

Rutin hasn't been studied enough in supplement doses to establish whether it works for the conditions listed (aging skin, diabetes, inflammatory bowel disease, and others). White oak has no effectiveness data on file.

The formula may support circulation, but we can't say it's proven to work for any specific condition, and the evidence is strongest for the vein-related uses.

The evidence, ingredient by ingredient White Oak Butcher's Broom Horse Chestnut Rutin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Butcher's broom and horse chestnut are generally well tolerated in the short term, but long-term safety data are limited for both. The most common side effects from butcher's broom are digestive — diarrhea, nausea, vomiting, heartburn, and indigestion.

Horse chestnut can cause dizziness, headache, itching, and gastrointestinal upset. White oak's high tannin content can irritate your digestive tract.

Rutin may cause headache, flushing, or rashes in some people and is likely safe in pregnancy but should be avoided at supplement doses unless your doctor says otherwise. Horse chestnut is unsafe in pregnancy and unsafe while breastfeeding.

Butcher's broom and white oak should be avoided during pregnancy and breastfeeding due to insufficient safety data. There isn't enough information on file about rutin's safety while breastfeeding.

Side effects, ingredient by ingredient White Oak Butcher's Broom Horse Chestnut Rutin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Rutin, Butcher's Broom, Horse Chestnut.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 362 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check if you're taking blood thinners or antiplatelet drugs (like warfarin or aspirin) — horse chestnut may increase bleeding risk. Also check antidiabetes drugs (rutin may lower blood sugar further), alpha-adrenergic antagonists like doxazosin or terazosin (butcher's broom may weaken them), and alpha-adrenergic agonists like pseudoephedrine (butcher's broom may strengthen them).

These are Moderate-severity concerns. We could not check the proprietary blend or enzyme blend for additional interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This formula is designed for circulation support using traditional vein-health herbs, with the strongest evidence for chronic venous insufficiency. If you take blood thinners, diabetes medications, or drugs for blood pressure or prostate symptoms, you need to check this with your pharmacist or doctor first — the interactions are real.

Pregnant and breastfeeding people should avoid it. It's generally well tolerated short-term, but long-term safety isn't well established.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Varicose Health & Circulation, straight from the product label.

Brand New Sun
Barcode (UPC) 39-3
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2012
DSLD ID 11597
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Varicose Health & Circulation by New Sun, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
45
UPC/BARCODE
39-3
IngredientAmount% DV
Proprietary Blend1200 mg--
White Oak0 NP--
Butcher's Broom0 NP--
Horse Chestnut0 NP--
Horse Chestnut (seed) Concentrate0 NP--
Rutin0 NP--
Enzyme Blend0 NP--

Other ingredients: Gelatin, Rice Flour, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Helps support healthy circulation.*

Precautions

Keep out of reach of children.

Do not use if safety seal is missing or broken.

Warning: If you are pregnant, nursing, taking any medications, or experiencing health issues, consult your doctor before use.

Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Recommendation: As a dietary supplement, take two capsules with meala twice daily.

FDA Disclaimer Statement

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General

Product No. 39-3 V3.0

FDA Statement of Identity

Dietary Supplement

Formulation

This product does not contain: yeast, corn, wheat, egg, starch, preservatives, artificial coloring or sweeteners.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Varicose Health & Circulation by New Sun label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Varicose Health & Circulation label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Varicose Health & Circulation by New Sun

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

1200 mg per serving

White Oak

No known
interactions
0 NP per serving

White oak bark is a traditional herbal remedy rich in tannins, used mostly as a tea or skin wash for diarrhea, sore throat, and minor skin problems. S...

White Oak monograph & interactions

Butcher's Broom

Interacts with
158 drugs
0 NP per serving

Butcher's broom is a plant extract most often used for circulation problems in the legs, such as chronic venous insufficiency, where some evidence sug...

Butcher's Broom monograph & interactions

Horse Chestnut

Interacts with
122 drugs
0 NP per serving

Horse chestnut seed extract is most often used for chronic venous insufficiency, where standardized products may help reduce leg swelling, pain, and h...

Horse Chestnut monograph & interactions

Horse Chestnut (seed) Concentrate

Interacts with
122 drugs
0 NP per serving

Horse chestnut seed extract is most often used for chronic venous insufficiency, where standardized products may help reduce leg swelling, pain, and h...

Horse Chestnut (seed) Concentrate monograph & interactions

Rutin

Interacts with
86 drugs
0 NP per serving Form: Buckwheat

Rutin is a plant flavonoid (often taken from buckwheat or citrus) that people use mainly for blood vessel and circulation problems like varicose veins...

Rutin monograph & interactions

Enzyme Blend

0 NP per serving Form: Amylase, Lipase, Protease

Other (inactive) ingredients: Gelatin, Rice Flour, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Varicose Health & Circulation by New Sun Drug Interactions

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 Go to the checker
362Drugs
362 Moderate

Ingredients driving the most interactions

Butcher's Broom 158
Horse Chestnut 122
Rutin 86

Individual Drug Interactions

The ingredients in Varicose Health & Circulation interact with 362 drugs. Click any drug to see the details.

3 of the 7 ingredients in Varicose Health & Circulation interact with drugs. Each result below shows which ingredient is responsible. Butcher's Broom Horse Chestnut Rutin

Each ingredient & the kinds of drugs it affects

For each ingredient in Varicose Health & Circulation with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Butcher's Broom2 drug types · 158 drugs

Alpha-Adrenergic Agonists

Theoretically, butcher's broom might increase the effects and adverse effects of alpha-adrenergic agonists.
Animal and in vitro studies show that butcher's broom has alpha-adrenergic agonist effects.

Likelihood Possible Evidence D
Alpha-Adrenergic Antagonists

Theoretically, butcher's broom might reduce the effects of alpha-adrenergic antagonists.
Animal and in vitro studies show that butcher's broom has alpha-adrenergic agonist effects.

Likelihood Possible Evidence D
Butcher's Broom full monograph & interactions

Horse Chestnut1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Horse chestnut may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Horse chestnut contains the constituent esculin which has been shown to have antithrombotic effects. Therefore, horse chestnut might have antiplatelet effects. This has not been shown in humans.

Likelihood Possible Evidence D
Horse Chestnut full monograph & interactions

Rutin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking rutin with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that rutin has hypoglycemic effects.

Likelihood Possible Evidence D
Rutin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Varicose Health & Circulation, from the product label.

New Sun

See all New Sun products
Name
New Sun
City
Hendersonville
State
NC
ZipCode
28792
Phone Number
1-800-544-0777
Web Address
www.newsun.net
Pharmacist Counseling Corner

Varicose Health & Circulation by New Sun: Common Questions

Does Varicose Health & Circulation by New Sun interact with any medications?
Yes. Based on its ingredients, Varicose Health & Circulation has a known interaction with 362 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Varicose Health & Circulation contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while I'm pregnant?
No. Horse chestnut is unsafe in pregnancy, and butcher's broom and white oak should be avoided because there isn't enough safety data. Talk with your doctor about whether circulation support is something you need right now.
What does rutin do in this formula?
Rutin is a plant compound with antioxidant properties. We don't have strong evidence it works for any specific condition at supplement doses, but it's included here as part of the circulation-support blend. It's the one ingredient that's likely safe in pregnancy, though you'd want to discuss it with your doctor if you're expecting.
Can I take this if I'm on blood thinners?
Probably not without checking first. Horse chestnut (which is in this formula twice) may have antiplatelet effects and could theoretically increase your bleeding risk. Don't start this without talking to your pharmacist or doctor about your blood thinner specifically.
What are the most common side effects?
Digestive upset is the main one — nausea, vomiting, diarrhea, heartburn, and indigestion from butcher's broom and white oak. Horse chestnut may cause dizziness, headache, itching, or gastrointestinal discomfort. These are usually mild and short-term, but if they persist, stop and let your pharmacist know.
Is this something I can take long-term?
The safety data are limited for long-term use. Butcher's broom and horse chestnut are studied and generally well tolerated for short-term use, but we don't have strong evidence they're safe to use indefinitely. Check with your pharmacist about how long it's reasonable to take this.
Can I breastfeed while taking this?
The safety data don't support it. Horse chestnut is unsafe while breastfeeding, butcher's broom and white oak haven't been studied enough to know, and rutin's safety isn't established at supplement doses. Talk with your doctor or lactation consultant before starting any circulation formula while nursing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Varicose Health & Circulation is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Varicose Health & Circulation label
Go deeper

The Full Monographs Behind Varicose Health & Circulation’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

White Oak

White oak bark is a traditional herbal remedy rich in tannins, used mostly as a tea or skin wash for diarrhea, sore throat, and minor skin problems. Solid human evidence is very limited, and...

Read the full White Oak monograph → Herb & supplement monograph

Butcher's Broom

Interacts with 158 drugs

Butcher's broom is a plant extract most often used for circulation problems in the legs, such as chronic venous insufficiency, where some evidence suggests it may help reduce swelling and di...

Read the full Butcher's Broom monograph → Herb & supplement monograph

Horse Chestnut

Interacts with 122 drugs

Horse chestnut seed extract is most often used for chronic venous insufficiency, where standardized products may help reduce leg swelling, pain, and heaviness. Raw, unprocessed horse chestnu...

Read the full Horse Chestnut monograph → Herb & supplement monograph

Rutin

Interacts with 86 drugs

Rutin is a plant flavonoid (often taken from buckwheat or citrus) that people use mainly for blood vessel and circulation problems like varicose veins and hemorrhoids. The evidence is limite...

Read the full Rutin monograph →
Sources

Sources & How We Checked

Varicose Health & Circulation's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 33 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

White Oak 2 references
  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbs and Supplements — MedlinePlus Source

See these in context on the White Oak monograph →

Butcher's Broom 8 references
  1. Beltramino R, Penenory A, Buceta AM. An open-label, randomized multicenter study comparing the efficacy and safety of Cyclo 3 Fort versus hydroxyethyl rutoside in chronic venous lymphatic insufficiency. Angiology 2000;51:535-44.. PubMed
  2. Redman DA. Ruscus aculeatus (butcher's broom) as a potential treatment for orthostatic hypotension, with a case report. J Altern Complement Med 2000;6:539-49..
  3. Landa, N., Aguirre, A., Goday, J., Raton, J. A., and Diaz-Perez, J. L. Allergic contact dermatitis from a vasoconstrictor cream. Contact Dermatitis 1990;22(5):290-291. PubMed
  4. Cluzan, R. V., Alliot, F., Ghabboun, S., and Pascot, M. Treatment of secondary lymphedema of the upper limb with CYCLO 3 FORT. Lymphology 1996;29(1):29-35.
  5. Parrado F, Buzzi A. A study of the efficacy and tolerability of a preparation containing Ruscus aculeatus in the treatment of chronic venous insufficiency of the lower limbs. Clin Drug Invest 1999;18(4):255-61. DOI
  6. Sadarmin PP, Timperley J. An unusual case of Butcher's Broom precipitating diabetic ketoacidosis. J Emerg Med 2013;45(3):e63-e65. PubMed
  7. Ramirez-Hernandez M, Garcia-Selles J, Merida-Fernandez C, Martinez-Escribano JA. Allergic contact dermatitis to ruscogenins. Contact Dermatitis 2006;54(1):60. PubMed
  8. European Medicines Agency. Assessment report on Ruscus Aculeatus L rhizome. EMEA/HMPC/261939/2007. London, September 4, 2008. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/Herbal_-_HMPC_assessment_report/2009/12/WC500018288.pdf. Acces

See these in context on the Butcher's Broom monograph →

Horse Chestnut 21 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Greeske K, Pohlmann BK. Horse chestnut seed extract-an effective therapy principle in general practice. Drug therapy of chronic venous insufficiency. Fortschr Med 1996;114:196-200.
  6. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  7. Takegoshi K, Tohyama T, Okuda K, et al. A case of Venoplant-induced hepatic injury. Gastroenterol Jpn 1986;21:62-5.
  8. Jaspersen-Schib R, Theus L, Guirguis-Oeschger M, et al. [Serious plant poisonings in Switzerland 1966-1994. Case analysis from the Swiss Toxicology Information Center]. Schweiz Med Wochenschr 1996;126:1085-98.
  9. Popp W, Horak F, Jager S, et al. Horse chestnut (Aesculus hippocastanum) pollen: a frequent cause of allergic sensitization in urban children. Allergy 1992;47:380-3.
  10. Diaz-Perales A, Collada C, Blanco C, et al. Cross-reactions in the latex-fruit syndrome: A relevant role of chitinases but not of complex asparagine-linked glycans. J Allergy Clin Immunol 1999;104:681-7. PubMed
  11. Blanco C, Diaz-Perales A, Collada C, et al. Class I chitinases as potential panallergens involved in the latex-fruit syndrome. J Allergy Clin Immunol 1999;103:507-13. PubMed
  12. Comaish JS, Kersey PJ. Contact dermatitis to extract of horse chestnut (esculin). Contact Dermatitis 1980;6:150-1. PubMed
  13. Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency (Cochrane Review). In: The Cochrane Library, Issue 3, 2004. Chichester, UK: John Wiley & Sons, Ltd. PubMed
  14. Ottillinger, B. and Greeske, K. Rational therapy of chronic venous insufficiency--chances and limits of the therapeutic use of horse-chestnut seeds extract. BMC.Cardiovasc.Disord. 2001;1(1):5. PubMed
  15. Pittler, M. H. and Ernst, E. Horse chestnut seed extract for chronic venous insufficiency. Cochrane.Database.Syst.Rev. 2004;(2):CD003230. PubMed
  16. Fang, Y., Zhao, L., Yan, F., Xia, X., Xu, D., and Cui, X. Escin improves sperm quality in male patients with varicocele-associated infertility. Phytomedicine. 2010;17(3-4):192-196. PubMed
  17. De Smet, P. A., Van den Eertwegh, A. J., Lesterhuis, W., and Stricker, B. H. Hepatotoxicity associated with herbal tablets. BMJ 7-13-1996;313(7049):92.
  18. Rehn, D., Unkauf, M., Klein, P., Jost, V., and Lucker, P. W. Comparative clinical efficacy and tolerability of oxerutins and horse chestnut extract in patients with chronic venous insufficiency. Arzneimittelforschung 1996;46(5):483-487.
  19. Edem E, Kahyaoglu B, Çakar MA. Acute Effusive Pericarditis due to Horse Chestnut Consumption. Am J Case Rep. 2016;17:305-8. PubMed
  20. Costa Santos D, Lérias G, Madruga I. Drug-induced Liver Injury Due to a Horse Chestnut Dietary Supplement. Eur J Case Rep Intern Med 2021;8(3):002389. PubMed
  21. Yi HY, Lee JY. Poisoning due to consumption of horse chestnut seed. Clin Exp Emerg Med 2021;8(4):333-335. PubMed

See these in context on the Horse Chestnut monograph →

Rutin 2 references
  1. Mehta DK (Ex Ed). British National Formulary, Number 37. British Medical Association and Royal Pharmaceutical Society of Great Britain: London, England, March 1999.
  2. Sun C, Wang L, Sun J, Wang Z, Tang Z. Hypoglycemic and hypolipidemic effects of rutin on hyperglycemic rats. J Tradit Chin Med. 2020;40(4):640-645.

See these in context on the Rutin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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