Major interaction on record — check this product against your medications before combining. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Vegan D3 5000 IU + K2 90 mcg Ingredients & Drug Interactions

by Enzymedica

Vegan D3 5000 IU + K2 90 mcg label
See full label image
Capsule Category: Fiber And Other Nutrients
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vegan D3 5000 IU + K2 90 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Vegan D3 5000 IU + K2 90 mcg is a dietary supplement by Enzymedica with 3 active ingredients. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are MenaQ7. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Vegan D3 5000 IU + K2 90 mcg by Enzymedica

Ask about any prescription or over-the-counter medication and we check it for interactions with Vegan D3 5000 IU + K2 90 mcg by Enzymedica — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Vegan D3 5000 IU + K2 90 mcg by Enzymedica

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains three active ingredients. MenaQ7 is a form of vitamin K, a nutrient your body uses to support bone health and normal blood clotting.

You're also getting vitamin D3 (cholecalciferol), which helps your body absorb calcium and maintain bone strength. The third active ingredient is prebiotic fiber, which feeds the beneficial bacteria in your gut.

The capsule itself is made from cellulose and water.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: immune health and bone strength.
  • We looked for evidence on: Osteoporosis, Vitamin K-dependent clotting factors deficiency (VKCFD), Hemorrhagic disease, Hypoprothrombinemia, Warfarin anticoagulation, calcium absorption — and 3 related terms.
  • The strongest evidence on file: Vitamin K is rated "Effective" for Hemorrhagic disease (Natural Medicines).
  • Also on file: Vitamin K is rated "Effective" for Hypoprothrombinemia, Warfarin anticoagulation, Vitamin K-dependent clotting factors deficiency (VKCFD).
  • Also on file: Vitamin K is rated "Possibly Effective" for Osteoporosis.

Vitamin K (MenaQ7) is effective for treating bleeding disorders tied to vitamin K deficiency and for maintaining the blood-clotting factors your body depends on. It's also possibly effective for osteoporosis — the data suggests it may help, but more research would strengthen that claim.

We don't have established effectiveness ratings in our data for vitamin D3 or prebiotic fiber in this product.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin K taken by mouth is generally well tolerated. The most common side effects are mild — nausea, diarrhea, stomach upset, and abdominal pain — and they're not the norm.

Vitamin K is rated likely safe in pregnancy and while breastfeeding. The safety notes on file advise that normal dietary amounts are fine, but you should check with your doctor before taking supplements, especially if you have any health conditions or take medications.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Vitamin K in this product has a Major interaction with warfarin and other blood thinners that depend on vitamin K metabolism to work. If you take warfarin, do not start this supplement without talking to your pharmacist or doctor first.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This is a vitamin K and D3 supplement that works well if you're looking to support bone health and normal clotting. If you take warfarin or any other blood thinner, stop and talk to your pharmacist first — vitamin K can interfere with how these drugs work.

Everyone else should still run their medications through our checker before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vegan D3 5000 IU + K2 90 mcg, straight from the product label.

Brand Enzymedica
Barcode (UPC) 670480220382
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2023
DSLD ID 296564
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vegan D3 5000 IU + K2 90 mcg by Enzymedica, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
670480220382
IngredientAmount% DV
MenaQ790 mcg75%
Vitamin D3125 mcg625%
Prebiotic Fiber150 mg--

Other ingredients: Cellulose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Enzymedica Natural Digestive Health & Wellness

MenaQ7 is a registered trademark of NattoPharma, Norway.

Formulation

Whole Food Source Immune Health Bone Strength Digestive Support

NON GMO

Vegan Dietary Supplement

Whole Food Sourced

3 Benefits in 1 Immune Health Shiitake mushrooms provide a vegan, whole food source of vitamin D3. Bone Strength Vitamin D3, combined with our soy-free K2 from chickpeas, plus inulin helps proper absorption of calcium into the bones. Digestive Support Inulin, a low glycemic agave prebiotic, helps to support the microbiome, which houses 70% of the immune system.

Contains NO: Gluten, milk, casein, soy, egg, artificial colors or flavors

Why mushrooms? Enzymedica's whole food sourced vegan vitamins D3 + K2 feeds a healthy immune and digestive system with beneficial nutrients to support strong bones.

Formula

USA grown mushrooms

Vegan Vitamins D3 + K2

Our D3 is naturally derived from USA grown shiitake mushrooms. When exposed to sunshine, shiitake naturally responds by producing plentiful vitamin D3. This unique mushroom food source delivers a powerful dose of 5,000 IU that is easy to digest and assimilate. When combined with vitamin D3, our soy-free K2 supports the proper absorption of calcium into the bones by activating osteocalcin. Our chickpea sourced vitamin K2 is the MK-7 form (MenaQ7), which has been proven to deliver the highest bioavailability. Inulin, a naturally occurring prebiotic derived from agave, is known to nourish the microbiome, which supports a healthy immune system, and has a low glycemic index.

FDA Statement of Identity

Vegan Dietary Supplement

Suggested/Recommended/Usage/Directions

Recommended Use: Take 1 capsule daily with food.

Precautions

For adults only.

Consult physician prior to use if pregnant, nursing, taking medications or have a medical condition. Warning: If taking blood-thinning medication, consult a healthcare practitioner before using.

Do not use if safety seal is broken or missing.

Please keep out of reach of children.

Storage

Keep closed in dry place; avoid excessive heat.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vegan D3 5000 IU + K2 90 mcg by Enzymedica label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vegan D3 5000 IU + K2 90 mcg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vegan D3 5000 IU + K2 90 mcg by Enzymedica

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

MenaQ7

Interacts with
2 drugs
90 mcg per serving Form: Vitamin K2

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

MenaQ7 monograph & interactions

Vitamin D3

125 mcg per serving Form: Cholecalciferol, Shiitake Mushroom

Prebiotic Fiber

150 mg per serving Form: Inulin

Other (inactive) ingredients: Cellulose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vegan D3 5000 IU + K2 90 mcg by Enzymedica Drug Interactions

Want to check YOUR meds against Vegan D3 5000 IU + K2 90 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

MenaQ7 2

Individual Drug Interactions

The ingredients in Vegan D3 5000 IU + K2 90 mcg interact with 2 drugs. Click any drug to see the details.

1 of the 3 ingredients in Vegan D3 5000 IU + K2 90 mcg interact with drugs. Each result below shows which ingredient is responsible. MenaQ7

Each ingredient & the kinds of drugs it affects

For each ingredient in Vegan D3 5000 IU + K2 90 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

MenaQ71 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
MenaQ7 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vegan D3 5000 IU + K2 90 mcg, from the product label.

Enzymedica

See all Enzymedica products
Name
Enzymedica, Inc.
Street Address
771 Commerce Drive
City
Venice
State
FL
ZipCode
34292
Phone Number
1-888-918-1118
Web Address
enzymedica.com
Pharmacist Counseling Corner

Vegan D3 5000 IU + K2 90 mcg by Enzymedica: Common Questions

Does Vegan D3 5000 IU + K2 90 mcg by Enzymedica interact with any medications?
Yes. Based on its ingredients, Vegan D3 5000 IU + K2 90 mcg has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vegan D3 5000 IU + K2 90 mcg contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on warfarin?
Not without talking to your doctor or pharmacist first. Vitamin K in this product can reduce how well warfarin works to keep your blood from clotting. Your prescriber may need to adjust your warfarin dose if you do take both, and your blood clotting levels will need to be checked regularly.
What are the side effects of vitamin K?
When taken by mouth, vitamin K is generally well tolerated. Some people experience mild nausea, diarrhea, stomach upset, or abdominal pain, but these aren't common. Serious side effects are very rare.
Is vitamin K safe during pregnancy or breastfeeding?
Yes, vitamin K is rated likely safe during pregnancy and while breastfeeding.
What does the vitamin K in this supplement do?
Vitamin K supports normal blood clotting and bone health. It's effective for treating bleeding disorders caused by vitamin K deficiency and may help with osteoporosis, though more research is needed on that last one.
Does this product have any fillers?
The capsule contains cellulose and water as inactive ingredients. Those are standard capsule materials.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vegan D3 5000 IU + K2 90 mcg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vegan D3 5000 IU + K2 90 mcg label
Go deeper

The Full Monographs Behind Vegan D3 5000 IU + K2 90 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin K

Interacts with 2 drugs

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but supplements are sometimes used for deficiency...

Read the full Vitamin K monograph →
Sources

Sources & How We Checked

Vegan D3 5000 IU + K2 90 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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