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Dietary supplement

Vitamin A 25,000 IU 7,500 mcg Ingredients & Drug Interactions

by Protocol For Life Balance

Vitamin A 25,000 IU 7,500 mcg label
See full label image
Softgel Capsule Category: Vitamin
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vitamin A 25,000 IU 7,500 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Vitamin A 25,000 IU 7,500 mcg is a dietary supplement by Protocol For Life Balance with 1 active ingredient. Its ingredients are commonly taken for eye and vision health, skin health and acne, immune support.Based on those ingredients, 387 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin A. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Vitamin A 25,000 IU 7,500 mcg by Protocol For Life Balance

Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin A 25,000 IU 7,500 mcg by Protocol For Life Balance — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Vitamin A 25,000 IU 7,500 mcg by Protocol For Life Balance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: vitamin A at 7,500 mcg (25,000 IU) per softgel. The remaining ingredients — bovine gelatin, glycerin, water, and extra virgin olive oil — are inactive excipients that help deliver the vitamin A.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Eye and vision health, skin health, immune support.
  • We looked for evidence on: Night vision, Cataracts, Corneal abrasion, Retinitis pigmentosa, Retinopathy of prematurity, Photoreactive keratectomy — and 4 related terms.
  • The strongest evidence on file: Vitamin A is rated "Possibly Effective" for Aging skin (Natural Medicines).
  • Also on file: Vitamin A is rated "Possibly Effective" for Night vision, Retinitis pigmentosa.
  • Also on file: Vitamin A is rated "Possibly Ineffective" for Melanoma.

The evidence shows vitamin A is effective for treating vitamin A deficiency itself. For other uses, the data in our files supports that it's possibly effective for oral leukoplakia (an abnormal mouth tissue condition), aging skin, measles, ulcerative colitis (a type of inflammatory bowel disease), and bronchopulmonary dysplasia (a lung condition in premature infants).

Outside of vitamin A deficiency, talk with your doctor or pharmacist about whether this dose is right for what you're trying to address.

The evidence, ingredient by ingredient Vitamin A

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

At recommended amounts, vitamin A is generally well tolerated. The catch is that it's fat-soluble, meaning your body stores it — it doesn't wash out in urine like water-soluble vitamins do.

This single dose of 25,000 IU is above the daily safe upper limit of 10,000 IU for adults, so it's crucial you don't exceed the label's directions and you're aware of vitamin A from other sources (like multivitamins or fortified foods). In high chronic doses, vitamin A can cause dry, cracking, itchy skin; hair loss; liver damage; and in very rare cases, serious neurological effects.

The safety data advises caution in pregnancy — especially with high-dose retinol, which carries a risk of birth defects. If you're pregnant, planning pregnancy, or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Vitamin A

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin A.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 388 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist if you're on retinoid medications (like isotretinoin or tretinoin), warfarin or other blood thinners, tetracycline antibiotics (like doxycycline), or any medications that can stress the liver. The interactions with retinoids are the most serious.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This supplement is appropriate for treating vitamin A deficiency and possibly for a handful of other conditions, but the dose is on the higher end and interactions with retinoid medications and blood thinners are Major concerns. Check your medications with the tool on this page before starting, avoid going over the label dose, and talk with your pharmacist if you're pregnant or on any prescription.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin A 25,000 IU 7,500 mcg, straight from the product label.

Brand Protocol For Life Balance
Barcode (UPC) 707359103405
Net contents 100 Softgel(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 337829
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Halal, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin A 25,000 IU 7,500 mcg by Protocol For Life Balance, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
100
UPC/BARCODE
707359103405
IngredientAmount% DV
Vitamin A7500 mcg833%

Other ingredients: Bovine Gelatin, Glycerin, Water, Extra Virgin Olive Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: Take 1 softgel daily with a meal, or as directed by your healthcare practitioner.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Cautions/Interactions: Not to be taken by pregnant or nursing women.

Vitamin A 25,000 IU is not for long-term usage; do not exceed recommended dose.

Consult your healthcare practitioner before taking this product if you are taking any medications (especially tretinoin or other retinoid medications, tetracycline antibiotics, hepatotoxic drugs, or anticoagulants) or if you have any health conditions.

Keep out of reach of children.

California Proposition 65 Warning: Consuming this product can expose you to chemicals including retinol, which is know to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov/food.

Healthy immune function Supports eye and skin health

Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, shellfish or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formula

Vitamin A 25,000 7,500 mcg (25,000 IU)

Cresent H (Halal)

Formulation

Non-GMO

Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, shellfish or sesame ingredients.

Natural color variation may occur in this product.

FDA Statement of Identity

A Dietary Supplement

Storage

Store in a cool, dry place after opening.

Seals/Symbols

Cresent H (Halal)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vitamin A 25,000 IU 7,500 mcg by Protocol For Life Balance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vitamin A 25,000 IU 7,500 mcg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vitamin A 25,000 IU 7,500 mcg by Protocol For Life Balance

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container100 Amounts shown are per serving.

Vitamin A

Interacts with
387 drugs
7500 mcg per serving Form: Fish Liver Oil, Retinyl Palmitate

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplemen...

Vitamin A monograph & interactions

Other (inactive) ingredients: Bovine Gelatin, Glycerin, Water, Extra Virgin Olive Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin A 25,000 IU 7,500 mcg by Protocol For Life Balance Drug Interactions

Want to check YOUR meds against Vitamin A 25,000 IU 7,500 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
387Drugs
9 Major 378 Moderate

Ingredients driving the most interactions

Vitamin A 387

Individual Drug Interactions

The ingredients in Vitamin A 25,000 IU 7,500 mcg interact with 387 drugs. Click any drug to see the details.

1 of the 1 ingredient in Vitamin A 25,000 IU 7,500 mcg interact with drugs. Each result below shows which ingredient is responsible. Vitamin A

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin A 25,000 IU 7,500 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin A4 drug types · 387 drugs

Retinoids

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.
Retinoids, which are vitamin A derivatives, could have additive toxic effects when taken with vitamin A supplements.

Likelihood Probable Evidence D
Hepatotoxic Drugs

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.
The tolerable upper intake level (UL) is the highest level of intake that is likely to pose no risk of adverse effects. Doses of vitamin A above the UL can cause hepatotoxicity, ranging from elevated liver enzymes to liver failure.

Likelihood Possible Evidence C
Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with high doses of vitamin A can increase the risk of pseudotumor cerebri.
Benign intracranial hypertension (pseudotumor cerebri) can occur with tetracyclines and with acute or chronic vitamin A toxicity. Case reports suggest that taking tetracyclines and vitamin A concurrently can increase the risk of this condition. Avoid high doses of vitamin A in people taking tetracyclines chronically.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, high doses of vitamin A could increase the risk of bleeding with warfarin.
Vitamin A toxicity is associated with hemorrhage and hypoprothrombinemia, possibly due to vitamin K antagonism. Advise patients taking warfarin to avoid doses of vitamin A above the tolerable upper intake level of 10,000 IU/day for adults.

Likelihood Possible Evidence D
Vitamin A full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vitamin A 25,000 IU 7,500 mcg, from the product label.

Protocol For Life Balance

See all Protocol For Life Balance products
Name
Protocol For Life Balance
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
protocolforlife.com
Pharmacist Counseling Corner

Vitamin A 25,000 IU 7,500 mcg by Protocol For Life Balance: Common Questions

Does Vitamin A 25,000 IU 7,500 mcg by Protocol For Life Balance interact with any medications?
Yes. Based on its ingredients, Vitamin A 25,000 IU 7,500 mcg has a known interaction with 387 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin A 25,000 IU 7,500 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this dose safe to take every day?
At 25,000 IU, this dose is above the recommended daily safe upper limit of 10,000 IU for adults. It's designed for short-term supplementation and shouldn't be taken daily without direction from your doctor. Stick to the label directions and don't combine it with other vitamin A sources.
Can I take this if I'm pregnant or breastfeeding?
The safety data shows mixed information — it's rated possibly unsafe in pregnancy because high-dose vitamin A can cause birth defects. If you're pregnant, planning to get pregnant, or breastfeeding, talk with your doctor or pharmacist before taking this product; they can advise you based on your individual situation.
What are the signs I'm taking too much vitamin A?
Early signs of too much vitamin A include dry, cracking skin and lips, itchy or peeling skin, headaches, dizziness, and blurred vision. In severe cases, you might experience fatigue, hair loss, or liver problems. If you notice any of these, stop taking it and contact your pharmacist or doctor right away.
Does this work for anti-aging or skin health?
The evidence in our data supports that vitamin A is possibly effective for aging skin. That said, this is a higher dose meant primarily for deficiency or other medical conditions, so talk with your dermatologist or pharmacist about whether it's the right choice for your skin goals.
What if I'm already taking a multivitamin with vitamin A?
You'll want to add up the total vitamin A from all your sources — your multivitamin, any other supplements, and this product. Going over 10,000 IU daily as an adult increases your risk of toxicity. Use the label to check your multivitamin's vitamin A content and talk with your pharmacist about your total intake.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vitamin A 25,000 IU 7,500 mcg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin A 25,000 IU 7,500 mcg label
Go deeper

The Full Monographs Behind Vitamin A 25,000 IU 7,500 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin A

Interacts with 387 drugs

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplements are mainly useful for correcting a tr...

Read the full Vitamin A monograph →
Sources

Sources & How We Checked

Vitamin A 25,000 IU 7,500 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 31 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin A 31 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Griffiths JK. The vitamin A paradox. J Pediatr 2000;137:604-7.. PubMed
  3. Hardman JG, Limbird LL, Molinoff PB, eds. Goodman and Gillman's The Pharmacological Basis of Therapeutics, 9th ed. New York, NY: McGraw-Hill, 1996.
  4. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  5. FDA Talk Paper. Vitamin A and birth defects (T95-56). Food and Drug Administration, U.S. Department of Health and Human Services, Rockville, MD. October 6, 1995.
  6. Russell RM. The vitamin A spectrum: from deficiency to toxicity. Am J Clin Nutr 2000;71:878-84. PubMed
  7. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  8. Feskanich D, Singh V, Willett WC, Colditz GA. Vitamin A intake and hip fractures among postmenopausal women. JAMA 2002;287:47-54. PubMed
  9. Melhus H, Michaelsson K, Kindmark A, et al. Excessive dietary intake of vitamin A is associated with reduced bone mineral density and increased risk for hip fracture. Ann Intern Med 1998;129:770-8. PubMed
  10. Michaelsson K, Lithell H, Vessby B, Melhus H. Serum retinol levels and the risk of fracture. N Engl J Med 2003;348:287-94.. PubMed
  11. Botterweck AA, van den Brandt PA, Goldbohm RA. Vitamins, carotenoids, dietary fiber, and the risk of gastric carcinoma: results from a prospective study after 6.3 years of follow-up. Cancer 2000;88:737-48.. DOI
  12. Meyskens FL Jr, Graham V, Chvapil M, et al. A phase I trial of beta-all-trans-retinoic acid delivered via a collagen sponge and a cervical cap for mild or moderate intraepithelial cervical neoplasia. J Natl Cancer Inst 1983;71:921-5..
  13. Hathcock JN, Hattan DG, Jenkins MY, et al. Evaluation of vitamin A toxicity. Am J Clin Nutr 1990;52:183-202.. PubMed
  14. Walters BN, Gubbay SS. Tetracycline and benign intracranial hypertension: report of five cases. Br Med J 1981;282:19-20.. PubMed
  15. Pearson MG, Littlewood SM, Bowden AN. Tetracycline and benign intracranial hypertension (letter). Br Med J 1981;282:568-9.. PubMed
  16. Azais-Braesco V, Pascal G. Vitamin A in pregnancy: requirements and safety limits. Am J Clin Nutr 2000;71:1325S-33S. PubMed
  17. Smedts HP, de Vries JH, Rakhshandehroo M, et al. High maternal vitamin E intake by diet or supplements is associated with congenital heart defects in the offspring. BJOG 2009;116:416-23. PubMed
  18. Grotto, I., Mimouni, M., Gdalevich, M., and Mimouni, D. Vitamin A supplementation and childhood morbidity from diarrhea and respiratory infections: a meta-analysis. J Pediatr 2003;142(3):297-304. PubMed
  19. Mahalanabis, D., Lahiri, M., Paul, D., Gupta, S., Gupta, A., Wahed, M. A., and Khaled, M. A. Randomized, double-blind, placebo-controlled clinical trial of the efficacy of treatment with zinc or vitamin A in infants and young children with severe acute l
  20. Long, K. Z., Montoya, Y., Hertzmark, E., Santos, J. I., and Rosado, J. L. A double-blind, randomized, clinical trial of the effect of vitamin A and zinc supplementation on diarrheal disease and respiratory tract infections in children in Mexico City, Mex
  21. Fritz, H., Kennedy, D., Fergusson, D., Fernandes, R., Doucette, S., Cooley, K., Seely, A., Sagar, S., Wong, R., and Seely, D. Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis. PLoS.One. 2011;6(6):e21107. PubMed
  22. Mayo-Wilson, E., Imdad, A., Herzer, K., Yakoob, M. Y., and Bhutta, Z. A. Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis. BMJ 2011;343:d5094. PubMed
  23. Mazumder S, Taneja S, Bhatia K, Yoshida S, Kaur J, Dube B, Toteja GS, Bahl R, Fontaine O, Martines J, Bhandari N; Neovita India Study Group. Efficacy of early neonatal supplementation with vitamin A to reduce mortality in infancy in Haryana, India (Neovit
  24. Baineni R, Gulati R, Delhi CK. Vitamin A toxicity presenting as bone pain. Arch Dis Child. 2017;102(6):556-8. PubMed
  25. Darlow BA, Graham PJ, Rojas-Reyes MX. Vitamin A supplementation to prevent mortality and short- and long-term morbidity in very low birth weight infants. Cochrane Database Syst Rev. 2016;(8):CD000501. PubMed
  26. Haider BA, Sharma R, Bhutta ZA. Neonatal vitamin A supplementation for the prevention of mortality and morbidity in term neonates in low and middle income countries. Cochrane Database Syst Rev. 2017;2:CD006980. PubMed
  27. Mohammad YM, Raslan IR, Al-Hussain FA. Idiopathic Intracranial Hypertension Induced by Topical Application of Vitamin A. J Neuroophthalmol. 2016;36(4):412-3. PubMed
  28. Masnadi Shirazi K, Nikniaz Z, Masnadi Shirazi A, Rohani M. Vitamin A supplementation decreases disease activity index in patients with ulcerative colitis: A randomized controlled clinical trial. Complement Ther Med. 2018 Dec;41:215-219. PubMed
  29. Ding Y, Hu P, Yang Y, et al. Impact of maternal daily oral low-dose vitamin A supplementation on the mother-infant pair: a randomised placebo-controlled trial in China. Nutrients 2021;13(7):2370. PubMed
  30. Knapik JJ, Hoedebecke SS. Vitamin A and bone fractures: systematic review and meta-analysis. J Spec Oper Med 2021;21(2):100-7. PubMed
  31. Imdad A, Mayo-Wilson E, Haykal MR, et al. Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age. Cochrane Database Syst Rev 2022;3(3):CD008524. PubMed

See these in context on the Vitamin A monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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