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Dietary supplement

Vitamin B1 (Thiamine Mononitrate) Ingredients & Drug Interactions

by BulkSupplements.com

Vitamin B1 (Thiamine Mononitrate) label
See full label image
Powder Category: Vitamin
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vitamin B1 (Thiamine Mononitrate) against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Vitamin B1 (Thiamine Mononitrate) is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for preventing or treating thiamine deficiency, beriberi, wernicke-korsakoff syndrome (alcohol-related).Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Thiamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Vitamin B1 (Thiamine Mononitrate) by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin B1 (Thiamine Mononitrate) by BulkSupplements.com — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Vitamin B1 (Thiamine Mononitrate) by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: thiamine (also called vitamin B1), a B vitamin your body needs to turn food into energy and keep your nerves working properly. The powder form means there are no inactive fillers or binders.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Thiamine (Vitamin B1) supplementation.
  • We looked for evidence on: Thiamine deficiency, Wernicke-Korsakoff syndrome (WKS), Beriberi, Energy metabolism.
  • The strongest evidence on file: Thiamine is rated "Effective" for Thiamine deficiency (Natural Medicines).
  • Also on file: Thiamine is rated "Effective" for Wernicke-Korsakoff syndrome (WKS).

Thiamine is effective for treating thiamine deficiency and for Wernicke-Korsakoff syndrome (a serious neurological condition linked to severe thiamine shortage). It's possibly effective for dysmenorrhea (menstrual cramping).

For mosquito repellent and heart failure, the evidence suggests it's possibly ineffective.

The evidence, ingredient by ingredient Thiamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Thiamine is generally very safe when you take it by mouth in normal amounts. Allergic reactions are rare — oral use might rarely cause dermatitis or other skin reactions, and injected thiamine can rarely trigger severe allergic responses, but these are uncommon.

Thiamine is needed during pregnancy and while breastfeeding; if you're using a supplement, take it only at the dose your doctor or midwife recommends.

Side effects, ingredient by ingredient Thiamine

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Thiamine.
  • The most serious interaction on file is rated Minor.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take trimethoprim (Proloprim) or related antibiotics, let your pharmacist know before adding this supplement — it can raise your thiamine levels. Check your full medication list with the search tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

This is a straightforward B1 supplement, useful if you have a deficiency or Wernicke-Korsakoff syndrome. If you take trimethoprim or other antibiotics, check with us first — we'll make sure the dose and timing work with your medications.

Talk to your pharmacist before starting if you're pregnant, breastfeeding, or on any prescription drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin B1 (Thiamine Mononitrate), straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X000HUZ4F5
Net contents 1 Kilogram(s); 35.3 Ounce(s)
Market status On market
Date entered into DSLD Apr 23, 2024
DSLD ID 311763
Product type Vitamin
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult Female (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin B1 (Thiamine Mononitrate) by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
100 mg
Maximum serving Sizes:
100 mg
Servings per container
10000
UPC/BARCODE
X000HUZ4F5
IngredientAmount% DV
Thiamine92 mg7667%

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

BulkSupplements.com Clean & Pure Bulk Supplements

Formulation

Free of: Soy, dairy, yeast, gluten

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 100 mg once daily, or as directed by a physician.

Storage

Store in a dry, cool, dark place.

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

General Statements

Use an accurate milligram scale to measure. Contents are sold by weight, not volume. Settling may occur. New

Formula

Vitamins for energy and tiredness for women

Vitamins for energy and tiredness for women VIT B

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vitamin B1 (Thiamine Mononitrate) by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vitamin B1 (Thiamine Mononitrate) label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vitamin B1 (Thiamine Mononitrate) by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size100 mg Dosage formPowder Servings per container10000 Amounts shown are per serving.

Thiamine

Interacts with
3 drugs
92 mg per serving Form: Vitamin B1

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get eno...

Thiamine monograph & interactions
Interaction report

Vitamin B1 (Thiamine Mononitrate) by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Vitamin B1 (Thiamine Mononitrate)?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Thiamine 3

Individual Drug Interactions

The ingredients in Vitamin B1 (Thiamine Mononitrate) interact with 3 drugs. Click any drug to see the details.

1 of the 1 ingredient in Vitamin B1 (Thiamine Mononitrate) interact with drugs. Each result below shows which ingredient is responsible. Thiamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin B1 (Thiamine Mononitrate) with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Thiamine1 drug type · 3 drugs

Trimethoprim (Proloprim)

Trimethoprim might increase blood levels of thiamine.
In vitro, animal, and clinical research suggest that trimethoprim inhibits intestinal thiamine transporter ThTR-2, hepatic transporter OCT1, and renal transporters OCT2, MATE1, and MATE2, resulting in paradoxically increased thiamine plasma concentrations.

Likelihood Probable Evidence B
Thiamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vitamin B1 (Thiamine Mononitrate), from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
bulksupplements.com
Pharmacist Counseling Corner

Vitamin B1 (Thiamine Mononitrate) by BulkSupplements.com: Common Questions

Does Vitamin B1 (Thiamine Mononitrate) by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Vitamin B1 (Thiamine Mononitrate) has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin B1 (Thiamine Mononitrate) contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is thiamine safe to take if I'm pregnant or breastfeeding?
Thiamine is needed during both pregnancy and breastfeeding. If you want to use a supplement, stick to the dose your doctor or midwife recommends rather than taking more on your own.
Will this help with my menstrual cramps?
There's possibly effective evidence for thiamine in dysmenorrhea — that's the medical term for painful periods. It's not a guarantee, but it's worth discussing with your doctor if cramps are a real problem for you.
Can I take thiamine if I'm on antibiotics?
Most antibiotics are fine, but trimethoprim (Proloprim) is a minor concern — it can raise how much thiamine stays in your body. Check with your pharmacist before combining them.
What are the side effects of thiamine?
Thiamine is very safe at normal doses. Allergic reactions are rare when taken by mouth — you might rarely see dermatitis or other skin reactions. Injected thiamine can rarely cause severe allergic responses, but that's uncommon too.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vitamin B1 (Thiamine Mononitrate) is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin B1 (Thiamine Mononitrate) label
Go deeper

The Full Monographs Behind Vitamin B1 (Thiamine Mononitrate)’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Thiamine

Interacts with 3 drugs

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get enough from food, but supplements are clear...

Read the full Thiamine monograph →
Sources

Sources & How We Checked

Vitamin B1 (Thiamine Mononitrate)'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Thiamine 7 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  4. Rogovik, A. L., Vohra, S., and Goldman, R. D. Safety considerations and potential interactions of vitamins: should vitamins be considered drugs? Ann.Pharmacother. 2010;44(2):311-324. PubMed
  5. Arruti N, Bernedo N, Audicana MT, Villarreal O, Uriel O, Muñoz D. Systemic allergic dermatitis caused by thiamine after iontophoresis. Contact Dermatitis. 2013 Dec;69(6):375-6. PubMed
  6. Thiamine hydrochloride injection package insert. Lake Zurich, IL: Fresenius Kabi, LLC; September 2019.
  7. Vora B, Wen A, Yee SW, et al. The Effect of Trimethoprim on Thiamine Absorption: A Transporter-Mediated Drug-Nutrient Interaction. Clin Pharmacol Ther 2023;114(2):381-392.

See these in context on the Thiamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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