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Dietary supplement

Vitamin K2 50 mcg Ingredients & Drug Interactions

by Vitacost

Vitamin K2 50 mcg label
See full label image
Softgel Capsule Category: Vitamin
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vitamin K2 50 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Vitamin K2 50 mcg is a dietary supplement by Vitacost with 1 active ingredient. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Vitamin K2 50 mcg by Vitacost

Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin K2 50 mcg by Vitacost — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Vitamin K2 50 mcg by Vitacost

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 24, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains one active ingredient: vitamin K2 at 50 micrograms per softgel. Vitamin K2 is a fat-soluble vitamin that supports your body's ability to form clots and activate certain clotting proteins — roles your blood and bones both depend on.

The softgel also contains several inactive ingredients (sunflower seed oil, gelatin, glycerin, water, natural caramel color, and titanium dioxide) that help deliver and preserve the vitamin.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: bone health support.
  • We looked for evidence on: Osteoporosis, bone density, bone strength, fracture prevention.
  • The strongest evidence on file: Vitamin K is rated "Possibly Effective" for Osteoporosis (Natural Medicines).

The evidence supports vitamin K2 for correcting vitamin K deficiency, including low levels of clotting proteins and bleeding disorders. It is also considered effective when used alongside warfarin to manage anticoagulation — though that use requires medical supervision.

For bone health and osteoporosis, the evidence is less settled: vitamin K2 is rated possibly effective, meaning the research is promising but not yet conclusive.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, vitamin K2 is generally well tolerated in the amounts found in food and most supplements. The most common side effects are mild: nausea, stomach upset, abdominal pain, and diarrhea — affecting a small number of users.

Pregnancy and breastfeeding data rate vitamin K2 as likely safe. However, because this product is for supplementation beyond diet and the facts advise checking with your doctor before taking supplements, talk it over with your provider if you are pregnant or nursing to make sure it fits your situation.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take warfarin (Coumadin) or any other blood thinner (anticoagulant), check with your doctor or pharmacist before starting this supplement — vitamin K2 can reverse or weaken its effect and is a Major interaction. This is the one you cannot skip.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Vitamin K2 makes sense if your doctor has identified a vitamin K deficiency or if you're interested in bone health support based on early evidence. The major caveat: if you take warfarin or any blood thinner, you must clear this with your doctor or pharmacist first, because vitamin K can undermine how those drugs protect you.

A quick conversation with your own healthcare provider will make sure it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin K2 50 mcg, straight from the product label.

Brand Vitacost
Barcode (UPC) 844197019397
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD Jan 25, 2017
DSLD ID 70231
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin K2 50 mcg by Vitacost, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
30
UPC/BARCODE
844197019397
IngredientAmount% DV
Vitamin K250 mcg63%

Other ingredients: Sunflower seed Oil, Gelatin, Glycerin, Water, natural Caramel color, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions As a dietary supplement for adults 18 years of age and over, take 1 softgel daily or as directed by a healthcare professional.

Storage

Keep dry and at room temperature (59(0)-75(0)F [15(0)-24(0)C]).

Formulation

Free of Milk, eggs, peanuts, crustacean shellfish, fish, gluten.

FDA Disclaimer Statement

Disclaimer These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warnings Pregnant or lactating women, diabetics, hypoglycemics and people with known medical conditions and/or taking drugs should consult with a licensed physician and/or pharmacist prior to taking dietary supplements.

Warnings Pregnant or lactating women, diabetics, hypoglycemics and people with known medical conditions and/or taking drugs should consult with a licensed physician and/or pharmacist prior to taking dietary supplements. Individuals taking anticoagulants (e.g., warfarin, heparin) or aspirin and other salicylates should consult with their physician before taking supplemtents containing vitamin K.

Keep out of reach of children.

Contains: Soy.

Formula

Vitacost Vitamin K2 - MenaQ7 description Natural vitamin K2 supplement for bone health support. Featuring MenaQ7 - a premium, clinically studied form of vitamin K2.

With MenaQ7 - a clinically studied form of vitamin K2

Features clinically studied MenaQ7 natural vitamin K2

Contains: Soy.

General Statements

Natural bone health support

Naturally derived from Japanese natto (fermented soybeans) Superior to K2 supplements made with the synthetic (MK-4) form Supplies 50 mcg per serving

What is Vitamin K? Vitamin K is a group of compounds known as quinones, needed by the body to make certain types of proteins required for normal blood coagulation and bone health. Vitamin K1 (phylloquinone) is found primarily in leafy green vegetables such as spinach and kale, while vitamin K2 (menaquinone) is produced by bacteria in both human and animal intestines.

How does Vitamin K support health? Vitamin K's primary function in the body is to aid in the production of Gla (gamma carboxyglutamic acid) proteins, which play a part in coagulation and anti-coagulation of blood. Vitamin K is also necessary for osteoblasts (bone-forming cells) to activate osteocalcin, a protein that binds calcium to bones. Therefore, adequate amounts of vitamin K make certain calcium is properly delivered to bones and arterial health is maintained.

Why choose Vitacost Vitamin K?

Derived from the Japanese food natto, not synthetically made. 50 mcg per single-softgel serving 30 serving per bottle Incredible quality at an everyday low, affordable price

About Vitacost Vitacost nutritional products are manufactured to high standards of quality, efficacy and saftey. Each Vitacost product meets or exceeds the standards and requirements set forth in the FDA's code or Federal Regulation (21 CFR, 111) Current Good Manufacturing Practices (cGMP).

Brand IP Statement(s)

With MenaQ7 - a clinically studied form of vitamin K2

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vitamin K2 50 mcg by Vitacost label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vitamin K2 50 mcg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vitamin K2 50 mcg by Vitacost

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Vitamin K2

Interacts with
2 drugs
50 mcg per serving Form: MenaQ7, Menaquinone

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 monograph & interactions

Other (inactive) ingredients: Sunflower seed Oil, Gelatin, Glycerin, Water, Natural Caramel color, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin K2 50 mcg by Vitacost Drug Interactions

Want to check YOUR meds against Vitamin K2 50 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

Vitamin K2 2

Individual Drug Interactions

The ingredients in Vitamin K2 50 mcg interact with 2 drugs. Click any drug to see the details.

1 of the 1 ingredient in Vitamin K2 50 mcg interact with drugs. Each result below shows which ingredient is responsible. Vitamin K2

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin K2 50 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K21 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
Vitamin K2 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vitamin K2 50 mcg, from the product label.

Vitacost

See all Vitacost products
Name
Vitacost
Pharmacist Counseling Corner

Vitamin K2 50 mcg by Vitacost: Common Questions

Does Vitamin K2 50 mcg by Vitacost interact with any medications?
Yes. Based on its ingredients, Vitamin K2 50 mcg has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin K2 50 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on warfarin?
Not without talking to your doctor first. Vitamin K2 directly opposes warfarin's blood-thinning effect and can make the drug less effective at preventing clots. Your provider may need to adjust your warfarin dose or monitor you differently if you decide to take it.
Will this upset my stomach?
Most people tolerate it fine. In those who do have side effects, the most common are mild — nausea, stomach upset, abdominal pain, or diarrhea. Taking it with food may help.
Is vitamin K2 safe if I'm pregnant or nursing?
The data rates it as likely safe during pregnancy and breastfeeding. That said, supplements go beyond what you get from diet, so talk with your doctor or midwife to confirm it's right for you before you start.
What does vitamin K2 actually do in my body?
It helps your body form blood clots and activate proteins your blood needs to work properly. Early evidence also suggests it may support bone health, though more research is needed there.
Does this product have a lot of fillers?
The softgel contains sunflower seed oil, gelatin, glycerin, water, caramel color, and titanium dioxide — typical ingredients used to make and deliver the vitamin. There are no unnecessary fillers beyond what's needed for the capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vitamin K2 50 mcg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin K2 50 mcg label
Go deeper

The Full Monographs Behind Vitamin K2 50 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin K

Interacts with 2 drugs

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but supplements are sometimes used for deficiency...

Read the full Vitamin K monograph →
Sources

Sources & How We Checked

Vitamin K2 50 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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