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Dietary supplement

Vitamin K2 MK-7 50 Ingredients & Drug Interactions

by ProCaps Laboratories

Vitamin K2 MK-7 50 label
See full label image
Capsule Category: Vitamin
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vitamin K2 MK-7 50 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Vitamin K2 MK-7 50 is a dietary supplement by ProCaps Laboratories with 1 active ingredient. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K Complex. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Vitamin K2 MK-7 50 by ProCaps Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin K2 MK-7 50 by ProCaps Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Vitamin K2 MK-7 50 by ProCaps Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 24, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “Vitamin K Complex” is a proprietary blend — the label gives one combined amount (100 mcg) without saying how much of each component you get.

This product contains 2 active ingredients: vitamin K1 and vitamin K2 (MK-7). Both are forms of vitamin K, a nutrient that supports blood clotting and bone health.

The capsule itself is made from extra virgin olive oil and a soft-gelatin shell.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Promotes bone and heart health.
  • We looked for evidence on: Cardiovascular disease (CVD), Osteoporosis, Warfarin anticoagulation, Vascular calcification, Bone mineral density.
  • The strongest evidence on file: Vitamin K is rated "Effective" for Warfarin anticoagulation (Natural Medicines).
  • Also on file: Vitamin K is rated "Possibly Effective" for Osteoporosis.
  • Also on file: Vitamin K is rated "Insufficient Reliable Evidence To Rate" for Cardiovascular disease (CVD).

The data shows vitamin K1 and K2 are both effective for treating vitamin K deficiency and clotting disorders, and both are effective for managing warfarin anticoagulation (blood thinner therapy) — though, as noted, taking a supplement can interfere with that therapy. Both forms are possibly effective for osteoporosis.

The evidence for bone health is not as strong as for clotting support.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, vitamin K is generally well tolerated. The most common side effects are mild gastrointestinal upset: nausea, stomach pain, and diarrhea.

Serious reactions are rare and have only been documented with intravenous (IV) forms, not oral supplements. The data supports that vitamin K is likely safe in pregnancy and while breastfeeding.

Because normal dietary amounts are fine but supplement doses carry interaction risk with certain medications, check with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Warfarin (Coumadin) and related blood thinners (anticoagulants): this is a Major interaction. Vitamin K can block warfarin's effects and lower your bleeding protection.

Do not start this product if you take warfarin without talking to your doctor or pharmacist first.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Vitamin K2 MK-7 50 is straightforward for someone who wants bone and blood-clotting support and isn't on blood thinners. If you take warfarin, this product is not something to start on your own — talk it over with your doctor or pharmacist first, since the supplement can reduce how well your blood thinner works.

Even if you're not on warfarin, run your medication list through the checker on this page before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin K2 MK-7 50, straight from the product label.

Brand ProCaps Laboratories
Barcode (UPC) 215978
Net contents 360 Easy-To-Swallow Capsule(s)
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 220469
Product type Vitamin
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin K2 MK-7 50 by ProCaps Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
360
UPC/BARCODE
215978
IngredientAmount% DV
Vitamin K150 mcg--
Vitamin K250 mcg--
Vitamin K Complex100 mcg83%

Other ingredients: extra virgin Olive Oil, Soft-Gelatin Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use Consume one capsule daily or as recommended by a health care professional. This product is most effective as part of a healthy diet and active lifestyle, along with one of Andrew Lessman's multi-vitamin-mineral formulas. For questions about the use of this product call 800.808.7311.

Precautions

Warning Unless directed by a physician, vitamin K is not for use with any anticoagulant drugs (Coumadin, Warfarin, Heparin, etc). If you have ever experienced any blood clotting abnormalities, consult with a health professional before using this or any Vitamin K-containing product.

General Statements

HSN www.HSN.com 800.944.9999 www.QVC.com 800.345.1515

All-solar manufacturing

Brand IP Statement(s)

2020 ProCaps Labs

Formula

Highest activity vitamin K2

Andrew Lessman’s Vitamin K2 MK-7 50 provides a high potency blend of Vitamin K in the form of Vitamin K-1 (Phytonadione) and, most importantly, as vitamin K-2 menaquinone-7 (MK-7) to deliver newly recognized and essential benefits to bone and heart health. Vitamin K's name originates from the role of vitamin K-1 in blood clotting (koagulation in German) but, today, its most important function centers around vitamin K-2 MK-7 and its now recognized role in the utilization of calcium within the body and, as a result, its indispensable role in both bone health, as well as heart and cardiovascular health. These far-reaching benefits to skeletal and cardiovascular health have now been consistently observed and established in the scientific literature. Our Vitamin K2 MK-7 50 is formulated to deliver an unsurpassed source of vitamin K-2 for optimum bone and heart health. Plus, for any person consuming calcium and vitamin D, vitamin K-2 MK-7 has been shown to ensure the greatest benefits of those essential nutrients. It is also important to note that the best source of vitamin K-2 is the unusual Japanese food called fermented natto from soybeans, which virtually no Americans consume. Fortunately, our Vitamin K2 MK-7 50 makes it easy and economical to obtain all the benefits of vitamin K-2 in a small easy-to-swallow capsule.

Formulation

Promotes bone and heart health

Contains no milk, soy, yeast, corn, wheat, gluten, sodium, salt, sugar, fat, cholesterol, color, preservative, common allergens or manufacturing additives. Contains no additives of any kind.

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vitamin K2 MK-7 50 by ProCaps Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vitamin K2 MK-7 50 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vitamin K2 MK-7 50 by ProCaps Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container360 Amounts shown are per serving.

Vitamin K Complex

Interacts with
2 drugs
100 mcg per serving

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K Complex monograph & interactions

Other (inactive) ingredients: Extra virgin Olive Oil, Soft-Gelatin Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin K2 MK-7 50 by ProCaps Laboratories Drug Interactions

Want to check YOUR meds against Vitamin K2 MK-7 50?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

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2Drugs
2 Major

Ingredients driving the most interactions

Vitamin K Complex 2

Individual Drug Interactions

The ingredients in Vitamin K2 MK-7 50 interact with 2 drugs. Click any drug to see the details.

1 of the 1 ingredient in Vitamin K2 MK-7 50 interact with drugs. Each result below shows which ingredient is responsible. Vitamin K Complex

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin K2 MK-7 50 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K Complex1 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
Vitamin K Complex full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vitamin K2 MK-7 50, from the product label.

ProCaps Laboratories

See all ProCaps Laboratories products
Name
ProCaps Laboratories
City
Henderson
State
NV
ZipCode
89011
Phone Number
800.800.1200
Web Address
www.ProCapsLabs.com
Pharmacist Counseling Corner

Vitamin K2 MK-7 50 by ProCaps Laboratories: Common Questions

Does Vitamin K2 MK-7 50 by ProCaps Laboratories interact with any medications?
Yes. Based on its ingredients, Vitamin K2 MK-7 50 has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin K2 MK-7 50 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on warfarin?
No — not without talking to your doctor or pharmacist first. Vitamin K directly interferes with how warfarin works and can make your blood thinner less effective, putting you at risk. Your provider may be able to adjust your warfarin dose or monitor you more closely, but you need their guidance before starting.
What's the difference between vitamin K1 and K2 in this product?
Both are forms of vitamin K and both have similar effects on blood clotting and bone health. K2 (specifically MK-7, the form in this product) is thought to be better absorbed and stay in your body longer than K1, but the data shows both are effective for clotting support.
Will this give me stomach problems?
Some people experience mild gastrointestinal side effects like nausea, stomach pain, or diarrhea when taking vitamin K by mouth. These are the most common adverse effects reported, but they're usually mild. Taking it with food may help.
Is it safe to take while I'm pregnant or breastfeeding?
Yes — vitamin K is rated as likely safe during pregnancy and while breastfeeding. The data supports its use in those situations.
Does this actually help osteoporosis?
The data rates vitamin K as possibly effective for osteoporosis, which means there's some evidence but it's not as strong as for other uses like blood clotting. If bone health is your main goal, talk with your doctor about whether this is the right choice for you.
What are the inactive ingredients?
The capsule is made from extra virgin olive oil and soft-gelatin material. There are no other fillers or binders in this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vitamin K2 MK-7 50 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin K2 MK-7 50 label
Go deeper

The Full Monographs Behind Vitamin K2 MK-7 50’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin K

Interacts with 2 drugs

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but supplements are sometimes used for deficiency...

Read the full Vitamin K monograph →
Sources

Sources & How We Checked

Vitamin K2 MK-7 50's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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