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Dietary supplement

Western Red Cedar Ingredients & Drug Interactions

by Hawaii Pharm

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Western Red Cedar is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for warts and skin growths, respiratory and immune support, cold and upper respiratory symptoms.Based on those ingredients, 576 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Western Red Cedar Leaf Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Western Red Cedar by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Western Red Cedar Leaf Extract (in dried form), also known as thuja. The liquid also includes alcohol, water, and glycerin as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Thuja product and its label doesn't state a use — see Thuja's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for Western Red Cedar against the common cold is insufficient — we don't have reliable data showing it works for that purpose.

The evidence, ingredient by ingredient Thuja

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Thuja contains thujone, a neurotoxic compound that can cause serious harm in large doses. High amounts have been reported to cause headache, nervous agitation, seizures, stomach upset, vomiting, abdominal pain, diarrhea, and in rare cases liver damage, kidney damage, and death.

Some people have also developed contact dermatitis (an itchy rash) from handling thuja plants due to limonene, one of its components. The safety data advises against use in pregnancy — thuja was traditionally used to trigger uterine contractions and menstruation.

It's also advised against while breastfeeding, as safety hasn't been established.

Side effects, ingredient by ingredient Thuja

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Thuja.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications; immunosuppressants / transplant drugs.
  • For scale: 576 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Do not use this product if you take seizure threshold lowering drugs (such as certain anesthetics), immunosuppressants (like cyclosporine, tacrolimus, or mycophenolate), or anticonvulsants (seizure medications). All three categories carry Moderate severity interactions with thuja's thujone content.

Check your exact medications with the tool on this page before considering it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Western Red Cedar is not recommended if you take seizure threshold lowering drugs, immunosuppressants, or anticonvulsants — the interactions are serious and we advise you to avoid it. Even outside of medications, thuja carries a real risk of toxicity at higher doses.

Talk to your pharmacist before using this product, and skip it entirely if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Western Red Cedar, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 840253654977
Net contents 4 Fluid Ounce(s); 120 Milliliter(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 332103
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Western Red Cedar by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 Milliliter(s)
Maximum serving Sizes:
1 Milliliter(s)
Servings per container
120
UPC/BARCODE
840253654977
IngredientAmount% DV
Western Red Cedar Leaf Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Hawaii Pharm Herbal Extract Highest quality since 2008

Suggested/Recommended/Usage/Directions

Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 ml, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.

Precautions

Warning: We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.

Keep out of the reach of children!

Storage

Store in a cool dry place.

Formulation

Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Only natural ingredients Identity and purity is laboratory verified

All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives

Organic alcohol based

Made in USA, Hawaii

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Scan this QR code to get more info or reorder www.Hawaiipharm.com

Formula

Thuja plicata

Organic alcohol based

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

USA Made in United States of America

See for yourself

Western Red Cedar by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Western Red Cedar by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 Milliliter(s) Dosage formLiquid Servings per container120 Amounts shown are per serving.

Western Red Cedar Leaf Extract, Dry

Interacts with
576 drugs
983 mg per serving

Thuja, also called northern white cedar or arborvitae, is a tree whose leaf and oil have a long history in folk and homeopathic medicine, especially f...

Western Red Cedar Leaf Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Western Red Cedar by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Western Red Cedar?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
576Drugs
576 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Western Red Cedar with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Western Red Cedar Leaf Extract, Dry3 drug types · 576 drugs

Anticonvulsants

Thuja products can contain thujone, which might lower the seizure threshold. Theoretically, this could decrease the effectiveness of anticonvulsants drugs.

Likelihood Possible Evidence D
Immunosuppressants

Thuja might stimulate immune function. Theoretically, taking thuja might decrease the effects of immunosuppressive therapy. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), and other corticosteroids (glucocorticoids).

Likelihood Possible Evidence D
Seizure Threshold Lowering Drugs

Thuja products can contains significant amounts of thujone, a neurotoxin. Theoretically, patients taking drugs that lower the seizure threshold might be at greater risk of seizure if they also take thuja. Advise patients taking these drugs to avoid thuja products. Some drugs that lower the seizure threshold include anesthetics (propofol, others), antiarrhythmics (mexiletine), antibiotics (amphotericin, penicillin, cephalosporins, imipenem), antidepressants (bupropion, others), antihistamines (cyproheptadine, others), immunosuppressants (cyclosporine), narcotics (fentanyl, others), stimulants (methylphenidate), theophylline, and others.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Western Red Cedar, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
Street Address
510 Sumner St STE 613
City
Honolulu
State
HI
ZipCode
96817
Phone Number
888-542-9244
Web Address
Hawaiipharm.com
Pharmacist Counseling Corner

Western Red Cedar by Hawaii Pharm: Common Questions

Does Western Red Cedar by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Western Red Cedar has a known interaction with 576 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Western Red Cedar contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. Thuja is traditionally used to stimulate the uterus and menstruation, so it's advised against in pregnancy. Safety hasn't been established for breastfeeding either, so you should avoid it then too. Talk with your doctor or pharmacist before use if you're pregnant, planning to become pregnant, or breastfeeding.
What are the side effects of thuja?
Large doses have been reported to cause headache, nervous agitation, seizures, stomach irritation, vomiting, abdominal pain, and diarrhea. In rare cases, thuja toxicity has caused liver damage, kidney damage, and death. Some people also develop an itchy rash (contact dermatitis) from handling thuja plants.
Does Western Red Cedar work for the common cold?
We don't have reliable evidence showing it works for that purpose. The data isn't established in what we hold.
What is thujone and why is it a concern?
Thujone is a neurotoxic compound found in thuja. It can be toxic if taken internally in large amounts, and it may lower your seizure threshold — a particular concern if you take seizure or seizure-prevention medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Western Red Cedar is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Western Red Cedar label
Go deeper

The Full Monographs Behind Western Red Cedar’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Western Red Cedar's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Thuja 10 references
  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Millet Y, Jouglard J, Steinmetz MD, et al. Toxicity of some essential plant oils. Clinical and experimental study. Clin Toxicol 1981;18:1485-98. PubMed
  4. Gohla SH, Haubeck HD, Neth RD. Mitogenic activity of high molecular polysaccharide fractions isolated from the Cupressaceae Thuja occidentale L. I. Macrophage-dependent induction of CD-4-positive T-helper (Th+) lymphocytes. Leukemia 1988;2:528-33.
  5. Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
  6. Henneicke-von Zepelin H, Hentschel C, Schnitker J, et al. Efficacy and safety of a fixed combination phytomedicine in the treatment of the common cold (acute viral respiratory tract infection): results of a randomised, double blind, placebo-controlled, m
  7. Naser, B., Bodinet, C., Tegtmeier, M., and Lindequist, U. Thuja occidentalis (Arbor vitae): A Review of its Pharmaceutical, Pharmacological and Clinical Properties. Evid.Based Complement Alternat.Med 2005;2(1):69-78.
  8. Patel R, Alavi F, Ortega S, Matela A. Herb-Induced Liver Injury by Cimicifuga racemosa and Thuja occidentalis Herbal Medications for Fertility. Case Rep Gastrointest Med 2021;2021:8858310. PubMed
  9. Ambooken B, Thomas M, Jisha KT. Papillary Eccrine Adenoma in a 5-year-old Girl Altered by Application of Thuja Ointment. J Cutan Aesthet Surg 2020;13(4):370-371. PubMed
  10. Badaoui A, Fougerousse AC. Contact dermatitis to linalool and limonene: Unusual sources of exposure. Ann Dermatol Venereol 2023;150(2):167-168. PubMed

See these in context on the Thuja monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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