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Dietary supplement

Wild Cherry 2,000 mg Ingredients & Drug Interactions

by Nature's Answer

Wild Cherry 2,000 mg label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Wild Cherry 2,000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Wild Cherry 2,000 mg is a dietary supplement by Nature's Answer with 1 active ingredient. Its ingredients are commonly taken for cough, bronchitis and respiratory irritation, sore throat.Based on those ingredients, 643 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Wild Cherry bark (Dioscorea villosa) root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Wild Cherry 2,000 mg by Nature's Answer

Ask about any prescription or over-the-counter medication and we check it for interactions with Wild Cherry 2,000 mg by Nature's Answer — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Wild Cherry 2,000 mg by Nature's Answer

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 24, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Wild Cherry 2,000 mg contains one active ingredient: wild cherry bark extract from the Dioscorea villosa root. The liquid formula also includes purified water, vegetable glycerin, and 12–15% certified organic alcohol as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Wild Cherry product and its label doesn't state a use — see Wild Cherry's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The data we hold does not include effectiveness ratings for wild cherry in this product. We cannot tell you what clinical evidence, if any, supports its use.

The evidence, ingredient by ingredient Wild Cherry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Wild cherry is generally considered safe in small amounts as found in commercial cough products, but the plant contains compounds that can form cyanide in the body, especially at high doses. Large amounts of wild cherry can lead to cyanide toxicity, which can be fatal.

A reported case involved a 56-year-old woman who consumed about 300 grams of wild cherries steeped in alcohol and presented to the hospital with headache, nausea, vomiting, confusion, severe shortness of breath, and eventually coma and muscle weakness. Because of these cyanide-producing compounds and the lack of established safety data, this product should be avoided during pregnancy and breastfeeding.

Side effects, ingredient by ingredient Wild Cherry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Wild Cherry.
  • The most serious interaction on file is rated Moderate.
  • For scale: 644 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Wild cherry may increase levels of drugs metabolized by cytochrome P450 3A4 (CYP3A4), a liver enzyme that processes many common medications including certain statins and antifungals. This is a Moderate-severity interaction that hasn't been observed in actual patients yet, but it's worth checking your medications before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is marketed at high doses (2,000 mg), so cyanide risk is a genuine concern you should discuss with your doctor or pharmacist before starting. It also may interact with hundreds of medications through effects on liver metabolism, though that interaction hasn't been confirmed in humans yet.

Check your exact medications with the tool on this page, and talk it over with your own healthcare provider before taking it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wild Cherry 2,000 mg, straight from the product label.

Brand Nature's Answer
Barcode (UPC) 083000005480
Net contents 2 fl. Oz.; 60 mL
Market status On market
Date entered into DSLD Jun 24, 2016
DSLD ID 60798
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wild Cherry 2,000 mg by Nature's Answer, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 mL
Maximum serving Sizes:
1 mL
Servings per container
60
UPC/BARCODE
083000005480
IngredientAmount% DV
Wild Cherry bark (Dioscorea villosa) root extract1000 mg--

Other ingredients: purified Water, Vegetable Glycerin, 12-15% certified organic Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Gluten Free

K Parve

Formula

K Parve

Prunis serotina

Low Alcohol

Brand IP Statement(s)

Bio-Chelated Cold Extraction Process

Advanced Botanical Fingerprint

Discover Nature's Answer

Our organic alcohol extracts are produced using our cold Bio-Chelated proprietary extraction process, yielding a Holistically Balanced Advanced Botanical Fingerprint extract in the same synergistic ratios as in the plant.

2015 Nature's Answer

General

9301A Rev. 515 1159

General Statements

Since 1972

Super concentrated 2,000 mg

Our facility is cGMP certified, organic and kosher certified.

Formulation

Gluten-Free

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1/2-1 mL (14-28 drops) three (3) times a day in a small amount of water. Shake well.

Precautions

Keep out of reach of children.

Warning: Do not use if pregnant or nursing.

Do not use if safety seal is damaged or missing.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Wild Cherry 2,000 mg by Nature's Answer label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Wild Cherry 2,000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Wild Cherry 2,000 mg by Nature's Answer

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.5 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Wild Cherry bark (Dioscorea villosa) root extract

Interacts with
643 drugs
1000 mg per serving

Wild cherry bark is a traditional cough remedy found in many old-fashioned cough syrups and lozenges, but there is little modern scientific evidence p...

Wild Cherry bark (Dioscorea villosa) root extract monograph & interactions

Other (inactive) ingredients: Purified Water, Vegetable Glycerin, 12-15% certified organic Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Wild Cherry 2,000 mg by Nature's Answer Drug Interactions

Want to check YOUR meds against Wild Cherry 2,000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
643Drugs
643 Moderate

Ingredients driving the most interactions

Wild Cherry bark (Dioscorea villosa) root extract 643

Individual Drug Interactions

The ingredients in Wild Cherry 2,000 mg interact with 643 drugs. Click any drug to see the details.

1 of the 1 ingredient in Wild Cherry 2,000 mg interact with drugs. Each result below shows which ingredient is responsible. Wild Cherry bark (Dioscorea villosa) root extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Wild Cherry 2,000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wild Cherry bark (Dioscorea villosa) root extract1 drug type · 643 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes. Theoretically, wild cherry might increase levels of drugs metabolized by CYP3A4. However, so far, this interaction has not been reported in humans.
Some drugs metabolized by CYP3A4 include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and others.

Likelihood Possible Evidence D
Wild Cherry bark (Dioscorea villosa) root extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Wild Cherry 2,000 mg, from the product label.

Nature's Answer

See all Nature's Answer products
Name
Nature's Answer
City
Hauppauge
State
NY
ZipCode
11788-3943
Phone Number
(800) 439-2324
Web Address
www.naturesanswer.com
Pharmacist Counseling Corner

Wild Cherry 2,000 mg by Nature's Answer: Common Questions

Does Wild Cherry 2,000 mg by Nature's Answer interact with any medications?
Yes. Based on its ingredients, Wild Cherry 2,000 mg has a known interaction with 643 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wild Cherry 2,000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is wild cherry safe to take while pregnant or breastfeeding?
No. The safety data advises against use during pregnancy (it's rated likely unsafe), and there isn't enough information to know whether it's safe while breastfeeding, so you should avoid it. Talk with your doctor or pharmacist about what's safe for you during these times.
Can I take too much wild cherry?
Yes. Large amounts of wild cherry can cause cyanide toxicity, which can be dangerous or fatal. A documented case involved a woman who consumed about 300 grams of wild cherries steeped in alcohol and became seriously ill with confusion, severe breathing problems, and coma. Because this product is a 2,000 mg dose, you should not exceed the recommended amount and should talk with your doctor before starting.
What is wild cherry used for?
Traditionally, wild cherry has been used in cough products, but we don't have effectiveness data on file for this specific supplement to tell you whether the evidence supports that use.
Why does the label say it interacts with 644 medications?
Wild cherry may inhibit an enzyme (CYP3A4) in your liver that breaks down many different drugs. That enzyme is responsible for metabolizing 644 different medications across many categories—cholesterol drugs, antifungals, and many others. Even though the interaction hasn't been seen in actual patients yet, it's important to check whether any of your medications depend on that enzyme.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Wild Cherry 2,000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wild Cherry 2,000 mg label
Go deeper

The Full Monographs Behind Wild Cherry 2,000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Wild Cherry

Interacts with 643 drugs

Wild cherry bark is a traditional cough remedy found in many old-fashioned cough syrups and lozenges, but there is little modern scientific evidence proving it works. The bark, leaves, and s...

Read the full Wild Cherry monograph →
Sources

Sources & How We Checked

Wild Cherry 2,000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wild Cherry 4 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  4. Pentore, R., Venneri, A., and Nichelli, P. Accidental choke-cherry poisoning: early symptoms and neurological sequelae of an unusual case of cyanide intoxication. Ital.J Neurol.Sci. 1996;17(3):233-235. PubMed

See these in context on the Wild Cherry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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