Nefazodone

Generic name: Pronounced as (nef ay' zoe done)
Brand names
  • Serzone®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 02/15/2018

A small number of children, teenagers, and young adults (up to 24 years of age) who took antidepressants ('mood elevators') such as nefazodone during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). Children, teenagers, and young adults who take antidepressants to treat depression or other mental illnesses may be more likely to become suicidal than children, teenagers, and young adults who do not take antidepressants to treat these conditions. However, there are also risks when depression is not treated in children and teenagers. Talk to your child's doctor about these risks and whether your child should take an antidepressant. Children younger than 18 years of age should not normally take nefazodone, but in some cases, a doctor may decide that nefazodone is the best medication to treat a child's condition.

You should know that your mental health may change in unexpected ways when you take nefazodone or other antidepressants even if you are an adult over 24 years of age. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own.

Your healthcare provider will want to see you often while you are taking nefazodone, especially at the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor.

The doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with nefazodone. Read the information carefully and ask your doctor or pharmacist if you have any questions. You also can obtain the Medication Guide from the FDA website: http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm.

No matter what your age, before you take an antidepressant, you, your parent, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments. You should also talk about the risks and benefits of not treating your condition. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal. This risk is higher if you or anyone in your family has or has ever had bipolar disorder (mood that changes from depressed to abnormally excited) or mania (frenzied, abnormally excited mood) or has thought about or attempted suicide. Talk to your doctor about your condition, symptoms, and personal and family medical history. You and your doctor will decide what type of treatment is right for you.

Nefazodone may cause liver damage, which can be severe or life-threatening. Tell your doctor if you have or have ever had liver disease. If you experience any of the following symptoms, call your doctor immediately: nausea, vomiting, loss of appetite, extreme tiredness, lack of energy, yellowing of the skin or eyes, unusual bleeding or bruising, dark-colored urine, pain in the upper right part of the stomach, or flu-like symptoms.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain tests to check your body's response to nefazodone.

Nefazodone is used to treat depression. Nefazodone is in a class of medications called serotonin modulators. It works by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance.

Nefazodone comes as a tablet to take by mouth. It is usually taken two times a day with or without food. Take nefazodone at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take nefazodone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor may start you on a low dose of nefazodone and gradually increase your dose, not more than once every week.

It may take several weeks or longer for you to feel the full benefit of nefazodone. Continue to take nefazodone even if you feel well. Do not stop taking nefazodone without talking to your doctor. If your doctor tells you to stop taking nefazodone, your doctor will probably want to decrease your dose gradually.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking nefazodone,

  • tell your doctor and pharmacist if you are allergic to nefazodone, trazodone (Desyrel), or any other medications.

  • tell your doctor if you are taking astemizole (Hismanal) (not available in the U.S.), carbamazepine (Tegretol), cisapride (Propulsid) (not available in the U.S.), pimozide (Orap), terfenadine (Seldane) (not available in the U.S.);or triazolam (Halcion).Your doctor will probably tell you not to take nefazodone.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: alprazolam (Xanax), anticoagulants ('blood thinners') such as warfarin (Coumadin); buspirone (BuSpar); cholesterol-lowering medications (statins) such as atorvastatin (Lipitor), lovastatin (Mevacor), and simvastatin (Zocor); cyclosporine (Neoral, Sandimmune); digoxin (Lanoxin); haloperidol (Haldol); medications for high blood pressure, medications for seizures, medications to treat anxiety; muscle relaxants; propranolol (Inderal); sedatives; sleeping pills; tacrolimus (Prograf); or tranquilizers. . If you have recently stopped taking fluoxetine (Prozac, Sarafem), your doctor may tell you to wait several weeks before beginning to take nefazodone. Also tell your doctor or pharmacist if you are taking the following medications or have stopped taking them within the past two weeks: monoamine oxidase (MAO) inhibitors such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, EMSAM, Zelapar) or tranylcypromine (Parnate). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you have or have ever had seizures; a heart attack, chest pain, a stroke, or other types of heart disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking nefazodone, call your doctor.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking nefazodone.

  • you should know that this medication may make you drowsy or affect your judgment, thinking, or motor skills. Do not drive a car or operate machinery until you know how this medication affects you.

  • Avoid drinking alcohol while taking nefazodone.

  • you should know that nefazodone may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking nefazodone. To help avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

  • you should know that diarrhea, vomiting, not drinking enough fluids, and sweating a lot can cause a drop in blood pressure, which may cause lightheadedness and fainting. Tell your doctor if you have any of these problems or develop them during your treatment.

Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Nefazodone may cause side effects. Call your doctor if any of these symptoms are severe or do not go away:

    • headache

    • difficulty concentrating

    • dry mouth

    • heartburn

    • flushing or feeling warm

    • pain, burning, numbness, or tingling in the hands or feet

    • constipation

  • Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNINGS or SPECIAL PRECAUTIONS sections, call your doctor immediately:

    • rash

    • hives

    • itching

    • difficulty breathing or swallowing

    • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

    • hoarseness

    • slow heartbeat

    • memory problems

    • blurred vision or vision changes

    • confusion

    • seizures

    • painful erection of the penis lasting more than 4 hours

  • Nefazodone may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

  • nausea

  • vomiting

  • drowsiness

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Repaglinide Repaglinide The risk or severity of hypoglycemia can be increased when Repaglinide is combined with Nefazodone.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection The risk or severity of hypoglycemia can be increased when Insulin glargine is combined with Nefazodone.
Delavirdine Delavirdine The metabolism of Nefazodone can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Nefazodone can be decreased when combined with Nevirapine.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Nefazodone.
Dolasetron Dolasetron The risk or severity of adverse effects can be increased when Nefazodone is combined with Dolasetron.
Aminophylline Aminophylline The metabolism of Aminophylline can be decreased when combined with Nefazodone.
Anagrelide Anagrelide The risk or severity of hemorrhage can be increased when Nefazodone is combined with Anagrelide.
Candesartan Candesartan Nefazodone may decrease the antihypertensive activities of Candesartan.
Cilostazol Cilostazol The metabolism of Cilostazol can be decreased when combined with Nefazodone.
Clopidogrel Clopidogrel The risk or severity of hemorrhage can be increased when Nefazodone is combined with Clopidogrel.
Diphenoxylate Diphenoxylate The risk or severity of serotonin syndrome can be increased when Diphenoxylate is combined with Nefazodone.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole Nefazodone may decrease the excretion rate of Erythromycin which could result in a higher serum level.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Nefazodone may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Fenofibrate Fenofibrate The metabolism of Fenofibrate can be decreased when combined with Nefazodone.
Guanfacine Guanfacine The metabolism of Guanfacine can be decreased when combined with Nefazodone.
Magnesium Hydroxide Magnesium Hydroxide Nefazodone may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Methylergonovine Methylergonovine The risk or severity of hypertension can be increased when Methylergometrine is combined with Nefazodone.
Miglitol Miglitol The risk or severity of hypoglycemia can be increased when Miglitol is combined with Nefazodone.
Mycophenolate Mycophenolate Mycophenolic acid may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Naratriptan Naratriptan The risk or severity of adverse effects can be increased when Naratriptan is combined with Nefazodone.
Olsalazine Olsalazine The risk or severity of gastrointestinal bleeding can be increased when Olsalazine is combined with Nefazodone.
Paregoric Paregoric The risk or severity of serotonin syndrome can be increased when Nefazodone is combined with Morphine.
Penbutolol Penbutolol The serum concentration of Acebutolol can be increased when it is combined with Nefazodone.
Pentazocine Pentazocine The risk or severity of serotonin syndrome can be increased when Pentazocine is combined with Nefazodone.
Potassium Potassium Potassium may increase the excretion rate of Nefazodone which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone Prednisone The metabolism of Prednisone can be decreased when combined with Nefazodone.
Ranitidine Ranitidine The metabolism of Nefazodone can be decreased when combined with Ranitidine.
Reserpine Reserpine The risk or severity of adverse effects can be increased when Reserpine is combined with Nefazodone.
Rizatriptan Rizatriptan The risk or severity of adverse effects can be increased when Rizatriptan is combined with Nefazodone.
Sumatriptan Sumatriptan The risk or severity of adverse effects can be increased when Sumatriptan is combined with Nefazodone.
Tacrolimus Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Nefazodone.
Tizanidine Tizanidine The risk or severity of adverse effects can be increased when Tizanidine is combined with Nefazodone.
Triamcinolone Triamcinolone The metabolism of Triamcinolone can be decreased when combined with Nefazodone.
Zolmitriptan Zolmitriptan The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Nefazodone.
Ampicillin Injection Ampicillin Injection Ampicillin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection Doxycycline may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Fluconazole Injection Fluconazole Injection Fluconazole may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Foscarnet Injection Foscarnet Injection Foscarnet may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Hydromorphone Injection Hydromorphone Injection The risk or severity of serotonin syndrome can be increased when Nefazodone is combined with Hydromorphone.
Levofloxacin Injection Levofloxacin Injection Levofloxacin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Meperidine Injection Meperidine Injection The risk or severity of serotonin syndrome can be increased when Nefazodone is combined with Meperidine.
Methylprednisolone Injection Methylprednisolone Injection The metabolism of Methylprednisolone can be decreased when combined with Nefazodone.
Metoclopramide Injection Metoclopramide Injection The risk or severity of adverse effects can be increased when Metoclopramide is combined with Nefazodone.
Morphine Injection Morphine Injection The risk or severity of serotonin syndrome can be increased when Nefazodone is combined with Morphine.
Pamidronate Injection Pamidronate Injection Pamidronic acid may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Vancomycin Injection Vancomycin Injection Nefazodone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Altretamine Altretamine Amphetamine may increase the serotonergic activities of Nefazodone.
Cefuroxime Cefuroxime Cefuroxime may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Cyclosporine Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Nefazodone.
Ondansetron Ondansetron The risk or severity of adverse effects can be increased when Ondansetron is combined with Nefazodone.
Enoxaparin Injection Enoxaparin Injection The risk or severity of hemorrhage can be increased when Nefazodone is combined with Enoxaparin.
Granisetron Granisetron The risk or severity of adverse effects can be increased when Nefazodone is combined with Granisetron.
Torsemide Torsemide Torasemide may increase the excretion rate of Nefazodone which could result in a lower serum level and potentially a reduction in efficacy.
Olanzapine Olanzapine Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Alosetron Alosetron The risk or severity of adverse effects can be increased when Nefazodone is combined with Alosetron.
Dofetilide Dofetilide The metabolism of Dofetilide can be decreased when combined with Nefazodone.
Entacapone Entacapone The risk or severity of adverse effects can be increased when Entacapone is combined with Nefazodone.
Eprosartan Eprosartan Nefazodone may decrease the antihypertensive activities of Eprosartan.
Hydroxychloroquine Hydroxychloroquine The metabolism of Nefazodone can be decreased when combined with Hydroxychloroquine.
Meloxicam Meloxicam The risk or severity of gastrointestinal bleeding can be increased when Nefazodone is combined with Meloxicam.
Oxcarbazepine Oxcarbazepine The risk or severity of adverse effects can be increased when Oxcarbazepine is combined with Nefazodone.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Telmisartan Telmisartan Telmisartan may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Temozolomide Temozolomide Temozolomide may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Zaleplon Zaleplon The risk or severity of adverse effects can be increased when Nefazodone is combined with Zaleplon.
Anakinra Anakinra The metabolism of Nefazodone can be increased when combined with Anakinra.
Desloratadine Desloratadine The risk or severity of adverse effects can be increased when Desloratadine is combined with Nefazodone.
Linezolid Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Nefazodone.
Pentosan Polysulfate Pentosan Polysulfate The risk or severity of hemorrhage can be increased when Nefazodone is combined with Pentosan polysulfate.
Trimipramine Trimipramine Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Etanercept Injection Etanercept Injection The metabolism of Nefazodone can be increased when combined with Etanercept.
Glycopyrrolate Glycopyrrolate Nefazodone may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Perindopril Perindopril Perindopril may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Tenofovir Tenofovir The metabolism of Tenofovir can be decreased when combined with Nefazodone.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate The risk or severity of gastrointestinal bleeding can be increased when Choline magnesium trisalicylate is combined with Nefazodone.
Sirolimus Sirolimus The metabolism of Sirolimus can be decreased when combined with Nefazodone.
Dutasteride Dutasteride The risk or severity of hypertension can be increased when Dutasteride is combined with Nefazodone.
Epinephrine Injection Epinephrine Injection The therapeutic efficacy of Epinephrine can be decreased when used in combination with Nefazodone.
Eplerenone Eplerenone The metabolism of Eplerenone can be decreased when combined with Nefazodone.
Escitalopram Escitalopram The risk or severity of serotonin syndrome can be increased when Nefazodone is combined with Escitalopram.
Olmesartan Olmesartan Olmesartan may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Zonisamide Zonisamide The risk or severity of adverse effects can be increased when Nefazodone is combined with Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Nefazodone can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole Nefazodone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole.
Atomoxetine Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Nefazodone.
Dexmethylphenidate Dexmethylphenidate The risk or severity of adverse effects can be increased when Dexmethylphenidate is combined with Nefazodone.
Ezetimibe Ezetimibe Ezetimibe may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Teriparatide Injection Teriparatide Injection The therapeutic efficacy of Teriparatide can be decreased when used in combination with Nefazodone.
Atazanavir Atazanavir The metabolism of Nefazodone can be decreased when combined with Atazanavir.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Nefazodone.
Eletriptan Eletriptan The metabolism of Eletriptan can be decreased when combined with Nefazodone.
Mefloquine Mefloquine The metabolism of Nefazodone can be decreased when combined with Mefloquine.
Rosuvastatin Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Nefazodone.
Vardenafil Vardenafil The metabolism of Vardenafil can be decreased when combined with Nefazodone.
Alfuzosin Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Nefazodone.
Emtricitabine Emtricitabine Emtricitabine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Memantine Memantine Memantine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Tegaserod Tegaserod The metabolism of Tegaserod can be decreased when combined with Nefazodone.
Tadalafil Tadalafil The serum concentration of Tadalafil can be increased when it is combined with Nefazodone.
Frovatriptan Frovatriptan The risk or severity of adverse effects can be increased when Frovatriptan is combined with Nefazodone.
Progesterone Progesterone Nefazodone may decrease the excretion rate of Progesterone which could result in a higher serum level.
Apomorphine Injection Apomorphine Injection The risk or severity of adverse effects can be increased when Apomorphine is combined with Nefazodone.
Infliximab Injection Infliximab Injection The metabolism of Nefazodone can be increased when combined with Infliximab.
Protriptyline Protriptyline The risk or severity of adverse effects can be increased when Protriptyline is combined with Nefazodone.
Duloxetine Duloxetine The metabolism of Nefazodone can be decreased when combined with Duloxetine.
Norethindrone Norethindrone The metabolism of Norethisterone can be decreased when combined with Nefazodone.
Tinidazole Tinidazole Tinidazole may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Trospium Trospium Nefazodone may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Bosentan Bosentan Nefazodone may decrease the excretion rate of Bosentan which could result in a higher serum level.
Cefditoren Cefditoren Cefdinir may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Cinacalcet Cinacalcet The metabolism of Nefazodone can be decreased when combined with Cinacalcet.
Cyanocobalamin Injection Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Erlotinib Erlotinib The metabolism of Erlotinib can be decreased when combined with Nefazodone.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Nefazodone is combined with Eszopiclone.
Ganciclovir Ganciclovir Ganciclovir may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Insulin Aspart (rDNA Origin) Injection Insulin Aspart (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Insulin aspart.
Ribavirin Ribavirin Ribavirin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Solifenacin Solifenacin Nefazodone may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Valganciclovir Valganciclovir Nefazodone may decrease the excretion rate of Valganciclovir which could result in a higher serum level.
Adefovir Adefovir Adefovir may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Dextroamphetamine Dextroamphetamine Amphetamine may increase the serotonergic activities of Nefazodone.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The metabolism of Nefazodone can be decreased when combined with Peginterferon alfa-2b.
Pramlintide Injection Pramlintide Injection The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Pramlintide.
Sodium Oxybate Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Nefazodone.
Exenatide Injection Exenatide Injection The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Exenatide.
Isocarboxazid Isocarboxazid Nefazodone may increase the serotonergic activities of Isocarboxazid.
Ramelteon Ramelteon The risk or severity of adverse effects can be increased when Nefazodone is combined with Ramelteon.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Nefazodone.
Fentanyl Fentanyl The metabolism of Fentanyl can be decreased when combined with Nefazodone.
Pregabalin Pregabalin The therapeutic efficacy of Nefazodone can be increased when used in combination with Pregabalin.
Phenylephrine Phenylephrine The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Nefazodone.
Tipranavir Tipranavir The metabolism of Tipranavir can be decreased when combined with Nefazodone.
Felbamate Felbamate The risk or severity of adverse effects can be increased when Nefazodone is combined with Felbamate.
Insulin Detemir (rDNA Origin) Injection Insulin Detemir (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Insulin detemir.
Ranolazine Ranolazine The metabolism of Ranolazine can be decreased when combined with Nefazodone.
Abatacept Injection Abatacept Injection The metabolism of Nefazodone can be increased when combined with Abatacept.
Rasagiline Rasagiline Rasagiline may increase the serotonergic activities of Nefazodone.
Imatinib Imatinib Imatinib may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Sitagliptin Sitagliptin The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Sitagliptin.
Varenicline Varenicline Nefazodone may decrease the excretion rate of Varenicline which could result in a higher serum level.
Gefitinib Gefitinib The metabolism of Nefazodone can be decreased when combined with Gefitinib.
Albuterol Albuterol The therapeutic efficacy of Salbutamol can be decreased when used in combination with Nefazodone.
Paliperidone Paliperidone Paliperidone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Bortezomib Bortezomib The metabolism of Bortezomib can be decreased when combined with Nefazodone.
Clofarabine Injection Clofarabine Injection Clofarabine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Insulin glulisine.
Lubiprostone Lubiprostone Lubiprostone may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Primaquine Primaquine The metabolism of Primaquine can be decreased when combined with Nefazodone.
Aliskiren Aliskiren Nefazodone may decrease the antihypertensive activities of Aliskiren.
Pemetrexed Injection Pemetrexed Injection Nefazodone may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Dimenhydrinate Dimenhydrinate The risk or severity of adverse effects can be increased when Dimenhydrinate is combined with Nefazodone.
Lisdexamfetamine Lisdexamfetamine The therapeutic efficacy of Nefazodone can be decreased when used in combination with Lisdexamfetamine.
Nabilone Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Nefazodone.
Retapamulin Retapamulin The metabolism of Retapamulin can be decreased when combined with Nefazodone.
Sorafenib Sorafenib The metabolism of Nefazodone can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Sunitinib can be decreased when combined with Nefazodone.
Dronabinol Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Nefazodone.
Lapatinib Lapatinib The metabolism of Lapatinib can be decreased when combined with Nefazodone.
Levocetirizine Levocetirizine The risk or severity of adverse effects can be increased when Nefazodone is combined with Levocetirizine.
Pegaptanib Injection Pegaptanib Injection Nefazodone may decrease the excretion rate of Pegaptanib which could result in a higher serum level.
Dasatinib Dasatinib The metabolism of Dasatinib can be decreased when combined with Nefazodone.
Mexiletine Mexiletine The metabolism of Mexiletine can be decreased when combined with Nefazodone.
Azacitidine Injection Azacitidine Injection Azacitidine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Temsirolimus Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Nefazodone.
Maraviroc Maraviroc The metabolism of Maraviroc can be decreased when combined with Nefazodone.
Lenalidomide Lenalidomide Lenalidomide may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Nilotinib Nilotinib The metabolism of Nilotinib can be decreased when combined with Nefazodone.
Budesonide Budesonide The metabolism of Budesonide can be decreased when combined with Nefazodone.
Desmopressin Desmopressin The risk or severity of hyponatremia can be increased when Nefazodone is combined with Desmopressin.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Nefazodone.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Nefazodone.
Doripenem Injection Doripenem Injection Nefazodone may decrease the excretion rate of Doripenem which could result in a higher serum level.
Arsenic Trioxide Injection Arsenic Trioxide Injection Nefazodone may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level.
Desvenlafaxine Desvenlafaxine The risk or severity of adverse effects can be increased when Nefazodone is combined with Desvenlafaxine.
Cevimeline Cevimeline Nefazodone may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Nebivolol Nebivolol The serum concentration of Nebivolol can be increased when it is combined with Nefazodone.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Nefazodone.
Certolizumab Injection Certolizumab Injection The metabolism of Certolizumab pegol can be increased when combined with Nefazodone.
Ixabepilone Injection Ixabepilone Injection The metabolism of Ixabepilone can be decreased when combined with Nefazodone.
Irinotecan Injection Irinotecan Injection The serum concentration of SN-38, an active metabolite of Irinotecan, can be increased when used in combination with Nefazodone.
Daptomycin Injection Daptomycin Injection Daptomycin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Methylnaltrexone Injection Methylnaltrexone Injection Nefazodone may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
Rufinamide Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Nefazodone.
Silodosin Silodosin Nefazodone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Silodosin.
Midazolam Midazolam The serum concentration of Midazolam can be increased when it is combined with Nefazodone.
Naltrexone Injection Naltrexone Injection The risk or severity of serotonin syndrome can be increased when Naltrexone is combined with Nefazodone.
Dexrazoxane Injection Dexrazoxane Injection Dexrazoxane may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Milnacipran Milnacipran The metabolism of Milnacipran can be decreased when combined with Nefazodone.
Plerixafor Injection Plerixafor Injection Nefazodone may decrease the excretion rate of Plerixafor which could result in a higher serum level.
Fesoterodine Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Nefazodone.
Betaxolol Betaxolol The serum concentration of Betaxolol can be increased when it is combined with Nefazodone.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Nefazodone.
Prasugrel Prasugrel The risk or severity of hemorrhage can be increased when Nefazodone is combined with Prasugrel.
Lacosamide Lacosamide The metabolism of Lacosamide can be decreased when combined with Nefazodone.
Everolimus Everolimus The metabolism of Everolimus can be decreased when combined with Nefazodone.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The metabolism of Nefazodone can be decreased when combined with Tolvaptan.
Dronedarone Dronedarone The metabolism of Dronedarone can be decreased when combined with Nefazodone.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Nefazodone.
Pralatrexate Injection Pralatrexate Injection Nefazodone may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection The risk or severity of adverse effects can be increased when Nefazodone is combined with Palonosetron.
Saxagliptin Saxagliptin The metabolism of Saxagliptin can be decreased when combined with Nefazodone.
Telavancin Injection Telavancin Injection Nefazodone may decrease the excretion rate of Telavancin which could result in a higher serum level.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Nefazodone.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Nefazodone.
Topotecan Topotecan Topotecan may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Golimumab Injection Golimumab Injection The metabolism of Nefazodone can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Pazopanib can be decreased when combined with Nefazodone.
Asenapine Asenapine Nefazodone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Asenapine.
Vigabatrin Vigabatrin The risk or severity of adverse effects can be increased when Vigabatrin is combined with Nefazodone.
Pitavastatin Pitavastatin Nefazodone may decrease the excretion rate of Pitavastatin which could result in a higher serum level.
Albendazole Albendazole The metabolism of Albendazole can be decreased when combined with Nefazodone.
Oxymorphone Oxymorphone The risk or severity of serotonin syndrome can be increased when Nefazodone is combined with Oxymorphone.
Dabigatran Dabigatran The risk or severity of hemorrhage can be increased when Nefazodone is combined with Dabigatran.
Liraglutide Injection Liraglutide Injection The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Liraglutide.
Tocilizumab Injection Tocilizumab Injection The metabolism of Nefazodone can be increased when combined with Tocilizumab.
Dalfampridine Dalfampridine Nefazodone may decrease the excretion rate of Dalfampridine which could result in a higher serum level.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Nefazodone.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Nefazodone.
Ceftaroline Injection Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Lurasidone Lurasidone Nefazodone may increase the hypotensive activities of Lurasidone.
Acetaminophen Injection Acetaminophen Injection Nefazodone may decrease the excretion rate of Acetaminophen which could result in a higher serum level.
Vilazodone Vilazodone The metabolism of Vilazodone can be decreased when combined with Nefazodone.
Ipilimumab Injection Ipilimumab Injection Nefazodone may decrease the excretion rate of Ipilimumab which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection Aldesleukin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Terbutaline Injection Terbutaline Injection The therapeutic efficacy of Terbutaline can be decreased when used in combination with Nefazodone.
Busulfan Injection Busulfan Injection The metabolism of Busulfan can be decreased when combined with Nefazodone.
Roflumilast Roflumilast The metabolism of Roflumilast can be decreased when combined with Nefazodone.
Linagliptin Linagliptin The metabolism of Linagliptin can be decreased when combined with Nefazodone.
Rilpivirine Rilpivirine The metabolism of Nefazodone can be decreased when combined with Rilpivirine.
Telaprevir Telaprevir The excretion of Glecaprevir can be decreased when combined with Nefazodone.
Potassium Iodide Potassium Iodide The therapeutic efficacy of Potassium Iodide can be decreased when used in combination with Nefazodone.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Nefazodone.
Abiraterone Abiraterone The metabolism of Abiraterone can be decreased when combined with Nefazodone.
Rivaroxaban Rivaroxaban The risk or severity of hemorrhage can be increased when Nefazodone is combined with Rivaroxaban.
Ticagrelor Ticagrelor The risk or severity of hemorrhage can be increased when Nefazodone is combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be decreased when combined with Nefazodone.
Ruxolitinib Ruxolitinib The metabolism of Ruxolitinib can be decreased when combined with Nefazodone.
Vandetanib Vandetanib The metabolism of Vandetanib can be decreased when combined with Nefazodone.
Clobazam Clobazam The metabolism of Nefazodone can be decreased when combined with Clobazam.
Vemurafenib Vemurafenib The metabolism of Nefazodone can be decreased when combined with Vemurafenib.
Ivacaftor Ivacaftor The metabolism of Ivacaftor can be decreased when combined with Nefazodone.
Deferiprone Deferiprone Nefazodone may decrease the excretion rate of Deferiprone which could result in a higher serum level.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Nefazodone.
Crizotinib Crizotinib The metabolism of Crizotinib can be decreased when combined with Nefazodone.
Cabergoline Cabergoline The metabolism of Cabergoline can be decreased when combined with Nefazodone.
Naloxone Injection Naloxone Injection Nefazodone may decrease the excretion rate of Naloxone which could result in a higher serum level.
Ambrisentan Ambrisentan The excretion of Ambrisentan can be decreased when combined with Nefazodone.
Fondaparinux Injection Fondaparinux Injection The risk or severity of hemorrhage can be increased when Nefazodone is combined with Fondaparinux.
Ezogabine Ezogabine The risk or severity of adverse effects can be increased when Nefazodone is combined with Tiagabine.
Iloprost Iloprost The risk or severity of hemorrhage can be increased when Nefazodone is combined with Iloprost.
Enzalutamide Enzalutamide Nefazodone may decrease the excretion rate of Enzalutamide which could result in a higher serum level.
Mirabegron Mirabegron The metabolism of Mirabegron can be decreased when combined with Nefazodone.
Regorafenib Regorafenib The metabolism of Regorafenib can be decreased when combined with Nefazodone.
Bosutinib Bosutinib The metabolism of Bosutinib can be decreased when combined with Nefazodone.
Corticotropin, Repository Injection Corticotropin, Repository Injection The metabolism of Corticotropin can be decreased when combined with Nefazodone.
Lorcaserin Lorcaserin The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Mecasermin.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Nefazodone.
Teduglutide Injection Teduglutide Injection Nefazodone may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Bedaquiline Bedaquiline The metabolism of Bedaquiline can be decreased when combined with Nefazodone.
Icosapent Ethyl Icosapent Ethyl The risk or severity of hemorrhage can be increased when Nefazodone is combined with Icosapent ethyl.
Tofacitinib Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Nefazodone.
Alogliptin Alogliptin The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Alogliptin.
Ponatinib Ponatinib The metabolism of Ponatinib can be decreased when combined with Nefazodone.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Nefazodone.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Nefazodone.
Apixaban Apixaban The risk or severity of hemorrhage can be increased when Nefazodone is combined with Apixaban.
Canagliflozin Canagliflozin The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Canagliflozin.
Methazolamide Methazolamide Methazolamide may increase the excretion rate of Nefazodone which could result in a lower serum level and potentially a reduction in efficacy.
Dabrafenib Dabrafenib The metabolism of Dabrafenib can be decreased when combined with Nefazodone.
Ospemifene Ospemifene The metabolism of Nefazodone can be decreased when combined with Ospemifene.
Trametinib Trametinib Nefazodone may decrease the excretion rate of Trametinib which could result in a higher serum level.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Nefazodone.
Ertapenem Injection Ertapenem Injection Ertapenem may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Vortioxetine Vortioxetine The risk or severity of adverse effects can be increased when Nefazodone is combined with Vortioxetine.
Perampanel Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Nefazodone.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Nefazodone.
Lomitapide Lomitapide The metabolism of Lomitapide can be decreased when combined with Nefazodone.
Avanafil Avanafil The risk or severity of hypotension, dyspepsia, and headache can be increased when Avanafil is combined with Nefazodone.
Ketorolac Injection Ketorolac Injection The risk or severity of gastrointestinal bleeding can be increased when Ketorolac is combined with Nefazodone.
Simeprevir Simeprevir Nefazodone may decrease the excretion rate of Simeprevir which could result in a higher serum level.
Sofosbuvir Sofosbuvir Nefazodone may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Dapagliflozin.
Apremilast Apremilast The metabolism of Apremilast can be increased when combined with Nefazodone.
Droxidopa Droxidopa The therapeutic efficacy of Droxidopa can be decreased when used in combination with Nefazodone.
Ceritinib Ceritinib The metabolism of Ceritinib can be decreased when combined with Nefazodone.
Siltuximab Injection Siltuximab Injection The metabolism of Nefazodone can be increased when combined with Siltuximab.
Albiglutide Injection Albiglutide Injection The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Albiglutide.
Eslicarbazepine Eslicarbazepine The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Nefazodone.
Idelalisib Idelalisib The metabolism of Idelalisib can be decreased when combined with Nefazodone.
Testosterone Injection Testosterone Injection Nefazodone may decrease the excretion rate of Testosterone which could result in a higher serum level.
Oritavancin Injection Oritavancin Injection The metabolism of Nefazodone can be decreased when combined with Oritavancin.
Empagliflozin Empagliflozin The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Empagliflozin.
Vorapaxar Vorapaxar The risk or severity of hemorrhage can be increased when Nefazodone is combined with Vorapaxar.
Hydrocodone Hydrocodone The metabolism of Hydrocodone can be decreased when combined with Nefazodone.
Suvorexant Suvorexant Nefazodone may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Dulaglutide Injection Dulaglutide Injection The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Dulaglutide.
Edoxaban Edoxaban The risk or severity of hemorrhage can be increased when Nefazodone is combined with Edoxaban.
Olaparib Olaparib The metabolism of Olaparib can be decreased when combined with Nefazodone.
Caspofungin Injection Caspofungin Injection The excretion of Caspofungin can be decreased when combined with Nefazodone.
Methamphetamine Methamphetamine The therapeutic efficacy of Nefazodone can be decreased when used in combination with Metamfetamine.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Nefazodone.
Riociguat Riociguat The serum concentration of Riociguat can be increased when it is combined with Nefazodone.
Lanreotide Injection Lanreotide Injection The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Lanreotide.
Nintedanib Nintedanib The metabolism of Nintedanib can be decreased when combined with Nefazodone.
Secukinumab Injection Secukinumab Injection The metabolism of Nefazodone can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection Risperidone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Palbociclib Palbociclib The metabolism of Palbociclib can be decreased when combined with Nefazodone.
Insulin Human Inhalation Insulin Human Inhalation The risk or severity of hypoglycemia can be increased when Insulin human is combined with Nefazodone.
Lenvatinib Lenvatinib The metabolism of Nefazodone can be decreased when combined with Lenvatinib.
Naloxegol Naloxegol The metabolism of Nefazodone can be decreased when combined with Naloxegol.
Panobinostat Panobinostat The metabolism of Panobinostat can be decreased when combined with Nefazodone.
Haloperidol Injection Haloperidol Injection The risk or severity of CNS depression can be increased when Haloperidol is combined with Nefazodone.
Deoxycholic Acid Injection Deoxycholic Acid Injection Deoxycholic acid may increase the excretion rate of Nefazodone which could result in a lower serum level and potentially a reduction in efficacy.
Amiloride Amiloride Amiloride may increase the excretion rate of Nefazodone which could result in a lower serum level and potentially a reduction in efficacy.
Isavuconazonium Injection Isavuconazonium Injection The serum concentration of Isavuconazonium can be increased when it is combined with Nefazodone.
Macitentan Macitentan Nefazodone may decrease the excretion rate of Macitentan which could result in a higher serum level.
Sonidegib Sonidegib The metabolism of Sonidegib can be decreased when combined with Nefazodone.
Flibanserin Flibanserin The metabolism of Flibanserin can be decreased when combined with Nefazodone.
Rolapitant Rolapitant The metabolism of Rolapitant can be decreased when combined with Nefazodone.
Prednisolone Prednisolone The metabolism of Prednisolone can be decreased when combined with Nefazodone.
Daclatasvir Daclatasvir The metabolism of Daclatasvir can be decreased when combined with Nefazodone.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Nefazodone.
Ziprasidone Injection Ziprasidone Injection The risk or severity of adverse effects can be increased when Ziprasidone is combined with Nefazodone.
Cariprazine Cariprazine The risk or severity of adverse effects can be increased when Nefazodone is combined with Cariprazine.
Penicillin G Procaine Injection Penicillin G Procaine Injection Nefazodone may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Eluxadoline Eluxadoline The risk or severity of serotonin syndrome can be increased when Nefazodone is combined with Eluxadoline.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Insulin degludec.
Cobimetinib Cobimetinib The metabolism of Cobimetinib can be decreased when combined with Nefazodone.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Nefazodone.
Osimertinib Osimertinib The metabolism of Osimertinib can be decreased when combined with Nefazodone.
Alectinib Alectinib The metabolism of Alectinib can be decreased when combined with Nefazodone.
Ixazomib Ixazomib The metabolism of Ixazomib can be decreased when combined with Nefazodone.
Lesinurad Lesinurad Nefazodone may decrease the excretion rate of Lesinurad which could result in a higher serum level.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Dexamethasone Injection Dexamethasone Injection The metabolism of Nefazodone can be decreased when combined with Dexamethasone.
Defibrotide Injection Defibrotide Injection The risk or severity of hemorrhage can be increased when Nefazodone is combined with Defibrotide.
Brivaracetam Injection Brivaracetam Injection The risk or severity of adverse effects can be increased when Nefazodone is combined with Brivaracetam.
Venetoclax Venetoclax The metabolism of Venetoclax can be decreased when combined with Nefazodone.
Cobicistat Cobicistat The metabolism of Nefazodone can be decreased when combined with Cobicistat.
Midodrine Midodrine The therapeutic efficacy of Midodrine can be decreased when used in combination with Nefazodone.
Selexipag Selexipag The excretion of Selexipag can be decreased when combined with Nefazodone.
Pimavanserin Pimavanserin The risk or severity of adverse effects can be increased when Nefazodone is combined with Pimavanserin.
Diphenhydramine Injection Diphenhydramine Injection The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Nefazodone.
Furosemide Injection Furosemide Injection Furosemide may increase the excretion rate of Nefazodone which could result in a lower serum level and potentially a reduction in efficacy.
Rucaparib Rucaparib The metabolism of Rucaparib can be decreased when combined with Nefazodone.
Lixisenatide Injection Lixisenatide Injection The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Lixisenatide.
Ribociclib Ribociclib The metabolism of Ribociclib can be decreased when combined with Nefazodone.
Parathyroid Hormone Injection Parathyroid Hormone Injection The therapeutic efficacy of Parathyroid hormone can be decreased when used in combination with Nefazodone.
Brigatinib Brigatinib The metabolism of Brigatinib can be decreased when combined with Nefazodone.
Doxepin (Insomnia) Doxepin (Insomnia) Doxepin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Deutetrabenazine Deutetrabenazine Nefazodone may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level.
Valbenazine Valbenazine Nefazodone may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Deflazacort Deflazacort The serum concentration of Deflazacort can be increased when it is combined with Nefazodone.
Safinamide Safinamide Safinamide may increase the serotonergic activities of Nefazodone.
Naldemedine Naldemedine Nefazodone may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Midostaurin Midostaurin The metabolism of Nefazodone can be decreased when combined with Midostaurin.
Neratinib Neratinib The serum concentration of Neratinib can be increased when it is combined with Nefazodone.
Abaloparatide Injection Abaloparatide Injection The therapeutic efficacy of Abaloparatide can be decreased when used in combination with Nefazodone.
Enasidenib Enasidenib The metabolism of Nefazodone can be decreased when combined with Enasidenib.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be decreased when combined with Nefazodone.
Benznidazole Benznidazole Nefazodone may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Nefazodone.
Delafloxacin Delafloxacin Nefazodone may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Abemaciclib Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Nefazodone.
Betrixaban Betrixaban The risk or severity of bleeding can be increased when Nefazodone is combined with Betrixaban.
Acalabrutinib Acalabrutinib The metabolism of Acalabrutinib can be decreased when combined with Nefazodone.
Letermovir Letermovir Letermovir may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Semaglutide Injection Semaglutide Injection The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Semaglutide.
Tetrabenazine Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Nefazodone.
Ertugliflozin Ertugliflozin The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Ertugliflozin.
Buprenorphine Injection Buprenorphine Injection Nefazodone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Apalutamide Apalutamide The metabolism of Nefazodone can be decreased when combined with Apalutamide.
Fostamatinib Fostamatinib The risk or severity of hypotension, dyspepsia, and headache can be increased when Fostamatinib is combined with Nefazodone.
Baricitinib Baricitinib The metabolism of Baricitinib can be decreased when combined with Nefazodone.
Lofexidine Lofexidine The therapeutic efficacy of Nefazodone can be increased when used in combination with Lofexidine.
Plazomicin Injection Plazomicin Injection Nefazodone may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Eliglustat Eliglustat The metabolism of Eliglustat can be decreased when combined with Nefazodone.
Encorafenib Encorafenib The metabolism of Encorafenib can be decreased when combined with Nefazodone.
Ivosidenib Ivosidenib The metabolism of Ivosidenib can be decreased when combined with Nefazodone.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Nefazodone.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Nefazodone.
Cannabidiol Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Nefazodone.
Dacomitinib Dacomitinib The metabolism of Dacomitinib can be decreased when combined with Nefazodone.
Duvelisib Duvelisib The metabolism of Duvelisib can be decreased when combined with Nefazodone.
Stiripentol Stiripentol The risk or severity of adverse effects can be increased when Stiripentol is combined with Nefazodone.
Gilteritinib Gilteritinib The therapeutic efficacy of Nefazodone can be decreased when used in combination with Gilteritinib.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Nefazodone.
Rifamycin Rifamycin The metabolism of Nefazodone can be decreased when combined with Rifamycin.
Prucalopride Prucalopride The metabolism of Prucalopride can be decreased when combined with Nefazodone.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Nefazodone can be increased when combined with Emapalumab.
Siponimod Siponimod The risk or severity of adverse effects can be increased when Nefazodone is combined with Siponimod.
Acyclovir Ophthalmic Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Caplacizumab-yhdp Injection Caplacizumab-yhdp Injection The risk or severity of hemorrhage can be increased when Nefazodone is combined with Caplacizumab.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Nefazodone.
Alpelisib Alpelisib The metabolism of Alpelisib can be decreased when combined with Nefazodone.
Brexanolone Injection Brexanolone Injection The risk or severity of adverse effects can be increased when Brexanolone is combined with Nefazodone.
Polatuzumab vedotin-piiq Injection Polatuzumab vedotin-piiq Injection The risk or severity of adverse effects can be increased when Nefazodone is combined with Polatuzumab vedotin.
Solriamfetol Solriamfetol The risk or severity of hypertension can be increased when Solriamfetol is combined with Nefazodone.
Darolutamide Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Nefazodone.
Triclabendazole Triclabendazole The metabolism of Nefazodone can be decreased when combined with Triclabendazole.
Entrectinib Entrectinib The metabolism of Entrectinib can be decreased when combined with Nefazodone.
Pexidartinib Pexidartinib The metabolism of Pexidartinib can be decreased when combined with Nefazodone.
Upadacitinib Upadacitinib The metabolism of Upadacitinib can be decreased when combined with Nefazodone.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Nefazodone.
Pitolisant Pitolisant The serum concentration of Nefazodone can be decreased when it is combined with Pitolisant.
Pretomanid Pretomanid The serum concentration of Pretomanid can be increased when it is combined with Nefazodone.
Fedratinib Fedratinib The metabolism of Nefazodone can be decreased when combined with Fedratinib.
Lefamulin Lefamulin The serum concentration of Lefamulin can be increased when it is combined with Nefazodone.
Phenytoin Injection Phenytoin Injection The risk or severity of adverse effects can be increased when Phenytoin is combined with Nefazodone.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Nefazodone.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Nefazodone.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Nefazodone.
Voxelotor Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Nefazodone.
Lumateperone Lumateperone The serum concentration of Nefazodone can be increased when it is combined with Lumateperone.
Lasmiditan Lasmiditan The risk or severity of serotonin syndrome can be increased when Lasmiditan is combined with Nefazodone.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Nefazodone.
Tazemetostat Tazemetostat The metabolism of Tazemetostat can be decreased when combined with Nefazodone.
Bempedoic Acid Bempedoic Acid The excretion of Bempedoic acid can be decreased when combined with Nefazodone.
Cenobamate Cenobamate The serum concentration of Nefazodone can be decreased when it is combined with Cenobamate.
Pemigatinib Pemigatinib The metabolism of Pemigatinib can be decreased when combined with Nefazodone.
Selumetinib Selumetinib The serum concentration of Selumetinib can be increased when it is combined with Nefazodone.
Rimegepant Rimegepant The metabolism of Rimegepant can be decreased when combined with Nefazodone.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Nefazodone.
Ripretinib Ripretinib The serum concentration of Ripretinib can be increased when it is combined with Nefazodone.
Selpercatinib Selpercatinib The serum concentration of Selpercatinib can be increased when it is combined with Nefazodone.
Capmatinib Capmatinib The serum concentration of Capmatinib can be increased when it is combined with Nefazodone.
Lemborexant Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Nefazodone.
Fenfluramine Fenfluramine The risk or severity of serotonin syndrome can be increased when Fenfluramine is combined with Nefazodone.
Lurbinectedin Injection Lurbinectedin Injection The serum concentration of Lurbinectedin can be increased when it is combined with Nefazodone.
Octreotide Octreotide The risk or severity of hypoglycemia can be increased when Octreotide is combined with Nefazodone.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection Nefazodone may decrease the excretion rate of Belantamab mafodotin which could result in a higher serum level.
Pralsetinib Pralsetinib The serum concentration of Nefazodone can be increased when it is combined with Pralsetinib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Nefazodone can be decreased when it is combined with Satralizumab.
Naxitamab-gqgk Injection Naxitamab-gqgk Injection The risk or severity of hypertension can be increased when Nefazodone is combined with Naxitamab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be decreased when combined with Nefazodone.
Viloxazine Viloxazine The risk or severity of adverse effects can be increased when Nefazodone is combined with Viloxazine.
Tobramycin Injection Tobramycin Injection Tobramycin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Theophylline Theophylline The metabolism of Theophylline can be decreased when combined with Nefazodone.
Fenoprofen Fenoprofen The risk or severity of gastrointestinal bleeding can be increased when Fenoprofen is combined with Nefazodone.
Indomethacin Indomethacin The risk or severity of gastrointestinal bleeding can be increased when Indomethacin is combined with Nefazodone.
Mefenamic Acid Mefenamic Acid The risk or severity of gastrointestinal bleeding can be increased when Mefenamic acid is combined with Nefazodone.
Naproxen Naproxen The risk or severity of gastrointestinal bleeding can be increased when Naproxen is combined with Nefazodone.
Tolmetin Tolmetin The risk or severity of gastrointestinal bleeding can be increased when Tolmetin is combined with Nefazodone.
Sulindac Sulindac The risk or severity of gastrointestinal bleeding can be increased when Sulindac is combined with Nefazodone.
Trazodone Trazodone The serum concentration of Nefazodone can be increased when it is combined with Trazodone.
Isotretinoin Isotretinoin Isotretinoin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Sucralfate Sucralfate Sucralfate may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Hydroxyurea Hydroxyurea The metabolism of Nefazodone can be decreased when combined with Hydroxyurea.
Floxuridine Floxuridine Floxuridine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Phenobarbital Phenobarbital The risk or severity of adverse effects can be increased when Phenobarbital is combined with Nefazodone.
Metaxalone Metaxalone The risk or severity of adverse effects can be increased when Metaxalone is combined with Nefazodone.
Methotrexate Injection Methotrexate Injection The metabolism of Methotrexate can be decreased when combined with Nefazodone.
Levorphanol Levorphanol The risk or severity of serotonin syndrome can be increased when Levorphanol is combined with Nefazodone.
Primidone Primidone The risk or severity of adverse effects can be increased when Primidone is combined with Nefazodone.
Methsuximide Methsuximide The risk or severity of adverse effects can be increased when Methsuximide is combined with Nefazodone.
Diethylpropion Diethylpropion The therapeutic efficacy of Nefazodone can be decreased when used in combination with Diethylpropion.
Chlorpromazine Chlorpromazine Chlorpromazine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Diazepam Diazepam The risk or severity of adverse effects can be increased when Diazepam is combined with Nefazodone.
Oxazepam Oxazepam The risk or severity of adverse effects can be increased when Oxazepam is combined with Nefazodone.
Flurazepam Flurazepam The risk or severity of adverse effects can be increased when Flurazepam is combined with Nefazodone.
Clorazepate Clorazepate The risk or severity of adverse effects can be increased when Clorazepic acid is combined with Nefazodone.
Lorazepam Lorazepam The metabolism of Nefazodone can be decreased when combined with Lorazepam.
Phenoxybenzamine Phenoxybenzamine Phenoxybenzamine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Carmustine Carmustine Carmustine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Amantadine Amantadine The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Nefazodone.
Codeine Codeine The risk or severity of serotonin syndrome can be increased when Nefazodone is combined with Codeine.
Meprobamate Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Nefazodone.
Chlordiazepoxide Chlordiazepoxide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Nefazodone.
Bromocriptine Bromocriptine Bromocriptine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Metaproterenol Metaproterenol The therapeutic efficacy of Orciprenaline can be decreased when used in combination with Nefazodone.
Tranylcypromine Tranylcypromine Tranylcypromine may increase the serotonergic activities of Nefazodone.
Phenelzine Phenelzine Phenelzine may increase the serotonergic activities of Nefazodone.
Procarbazine Procarbazine Procarbazine may increase the serotonergic activities of Nefazodone.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of adverse effects can be increased when Nefazodone is combined with Ergoloid mesylate.
Tetracycline Tetracycline Tetracycline may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Nefazodone.
Prochlorperazine Prochlorperazine The metabolism of Nefazodone can be decreased when combined with Prochlorperazine.
Thioridazine Thioridazine Thioridazine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Trifluoperazine Trifluoperazine Trifluoperazine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Bleomycin Bleomycin Bleomycin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Sulfadiazine Sulfadiazine The risk or severity of hypoglycemia can be increased when Sulfadiazine is combined with Nefazodone.
Oxycodone Oxycodone The risk or severity of serotonin syndrome can be increased when Nefazodone is combined with Oxycodone.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Nefazodone.
Oxybutynin Oxybutynin The metabolism of Nefazodone can be decreased when combined with Oxybutynin.
Benztropine Benztropine Benzatropine may increase the central nervous system depressant (CNS depressant) activities of Nefazodone.
Maprotiline Maprotiline The risk or severity of adverse effects can be increased when Maprotiline is combined with Nefazodone.
Ibuprofen Ibuprofen The risk or severity of gastrointestinal bleeding can be increased when Ibuprofen is combined with Nefazodone.
Trihexyphenidyl Trihexyphenidyl Nefazodone may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine Orphenadrine Nefazodone may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine Perphenazine The risk or severity of adverse effects can be increased when Perphenazine is combined with Nefazodone.
Azathioprine Azathioprine Azathioprine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Fluphenazine Fluphenazine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Nefazodone.
Phentermine Phentermine The therapeutic efficacy of Nefazodone can be decreased when used in combination with Phentermine.
Methylphenidate Methylphenidate Methylphenidate may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Amoxapine Amoxapine Amoxapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Sulfasalazine Sulfasalazine The risk or severity of gastrointestinal bleeding can be increased when Sulfasalazine is combined with Nefazodone.
Hydrocortisone Hydrocortisone The metabolism of Hydrocortisone can be decreased when combined with Nefazodone.
Doxorubicin Doxorubicin The metabolism of Nefazodone can be decreased when combined with Doxorubicin.
Phenazopyridine Phenazopyridine Phenazopyridine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Carbamazepine Carbamazepine The serum concentration of Nefazodone can be decreased when it is combined with Carbamazepine.
Molindone Molindone The risk or severity of adverse effects can be increased when Nefazodone is combined with Molindone.
Methyldopa Methyldopa Methyldopa may increase the tachycardic activities of Nefazodone.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Nefazodone.
Prazosin Prazosin Prazosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Hydralazine Hydralazine Nefazodone may decrease the excretion rate of Hydralazine which could result in a higher serum level.
Cimetidine Cimetidine The metabolism of Nefazodone can be decreased when combined with Cimetidine.
Gentamicin Injection Gentamicin Injection Gentamicin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Warfarin Warfarin The serum concentration of Warfarin can be increased when it is combined with Nefazodone.
Clonazepam Clonazepam The risk or severity of adverse effects can be increased when Nefazodone is combined with Clonazepam.
Loperamide Loperamide The risk or severity of hypotension can be increased when Nefazodone is combined with Loperamide.
Promethazine Promethazine The risk or severity of adverse effects can be increased when Promethazine is combined with Nefazodone.
Meclofenamate Meclofenamate The risk or severity of gastrointestinal bleeding can be increased when Meclofenamic acid is combined with Nefazodone.
Daunorubicin Daunorubicin Daunorubicin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Nitrofurantoin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Digoxin Digoxin The serum concentration of Digoxin can be increased when it is combined with Nefazodone.
Loxapine Loxapine The risk or severity of adverse effects can be increased when Loxapine is combined with Nefazodone.
Chloroquine Chloroquine The metabolism of Chloroquine can be decreased when combined with Nefazodone.
Quinine Quinine The metabolism of Quinine can be decreased when combined with Nefazodone.
Ethosuximide Ethosuximide The risk or severity of adverse effects can be increased when Ethosuximide is combined with Nefazodone.
Triamterene Triamterene Triamterene may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Sulfinpyrazone Sulfinpyrazone Sulfinpyrazone may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Chlorothiazide Chlorothiazide The risk or severity of hyponatremia can be increased when Nefazodone is combined with Chlorothiazide.
Chlorthalidone Chlorthalidone The risk or severity of hyponatremia can be increased when Nefazodone is combined with Chlorthalidone.
Metolazone Metolazone The risk or severity of hyponatremia can be increased when Nefazodone is combined with Metolazone.
Isosorbide Isosorbide Isosorbide may increase the excretion rate of Nefazodone which could result in a lower serum level and potentially a reduction in efficacy.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Nefazodone.
Secobarbital Secobarbital The risk or severity of adverse effects can be increased when Secobarbital is combined with Nefazodone.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Nefazodone.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Nefazodone.
Imipramine Imipramine Imipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Probenecid Probenecid Probenecid may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Quinidine Quinidine Nefazodone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Quinidine.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Nefazodone.
Isoniazid Isoniazid The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Nefazodone.
Pyrazinamide Pyrazinamide Pyrazinamide may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Rifampin Rifampin Nefazodone may decrease the excretion rate of Rifampicin which could result in a higher serum level.
Disopyramide Disopyramide The risk or severity of hypoglycemia can be increased when Disopyramide is combined with Nefazodone.
Valproic Acid Valproic Acid The risk or severity of adverse effects can be increased when Valproic acid is combined with Nefazodone.
Tamoxifen Tamoxifen The metabolism of Nefazodone can be decreased when combined with Tamoxifen.
Butabarbital Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Nefazodone.
Levothyroxine Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Nefazodone.
Liothyronine Liothyronine Liothyronine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Methimazole Methimazole The metabolism of Nefazodone can be decreased when combined with Methimazole.
Propylthiouracil Propylthiouracil The therapeutic efficacy of Propylthiouracil can be decreased when used in combination with Nefazodone.
Chlorpropamide Chlorpropamide The risk or severity of hypoglycemia can be increased when Chlorpropamide is combined with Nefazodone.
Tolbutamide Tolbutamide The risk or severity of hypoglycemia can be increased when Tolbutamide is combined with Nefazodone.
Tolazamide Tolazamide The risk or severity of hypoglycemia can be increased when Tolazamide is combined with Nefazodone.
Dextromethorphan Dextromethorphan The risk or severity of adverse effects can be increased when Nefazodone is combined with Dextromethorphan.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Nefazodone is combined with Cyclobenzaprine.
Niacin Niacin The metabolism of Nefazodone can be decreased when combined with Niacin.
Baclofen Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Nefazodone.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Nefazodone.
Cyproheptadine Cyproheptadine The therapeutic efficacy of Nefazodone can be decreased when used in combination with Cyproheptadine.
Clemastine Clemastine The risk or severity of adverse effects can be increased when Clemastine is combined with Nefazodone.
Chlorpheniramine Chlorpheniramine The risk or severity of adverse effects can be increased when Nefazodone is combined with Chlorpheniramine.
Brompheniramine Brompheniramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Nefazodone.
Meclizine Meclizine The risk or severity of adverse effects can be increased when Meclizine is combined with Nefazodone.
Ethambutol Ethambutol Ethambutol may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Methyclothiazide Methyclothiazide The risk or severity of hyponatremia can be increased when Nefazodone is combined with Methyclothiazide.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of hyponatremia can be increased when Nefazodone is combined with Hydrochlorothiazide.
Dantrolene Dantrolene The risk or severity of adverse effects can be increased when Dantrolene is combined with Nefazodone.
Chlorzoxazone Chlorzoxazone The risk or severity of adverse effects can be increased when Nefazodone is combined with Chlorzoxazone.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Nefazodone.
Methocarbamol Methocarbamol The risk or severity of adverse effects can be increased when Methocarbamol is combined with Nefazodone.
Pyridoxine Pyridoxine Pyridoxine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Folic Acid Folic Acid Folic acid may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Disulfiram Disulfiram Disulfiram may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The serum concentration of Nefazodone can be increased when it is combined with Propranolol.
Minoxidil Minoxidil Nefazodone may decrease the antihypertensive activities of Minoxidil.
Pseudoephedrine Pseudoephedrine The therapeutic efficacy of Nefazodone can be decreased when used in combination with Pseudoephedrine.
Nortriptyline Nortriptyline Nortriptyline may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Spironolactone Spironolactone Spironolactone may increase the excretion rate of Nefazodone which could result in a lower serum level and potentially a reduction in efficacy.
Amphotericin B Injection Amphotericin B Injection Amphotericin B may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Phytonadione Phytonadione Phylloquinone may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Amikacin Injection Amikacin Injection Amikacin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Nadolol Nadolol The serum concentration of Nadolol can be increased when it is combined with Nefazodone.
Butorphanol Injection Butorphanol Injection The risk or severity of serotonin syndrome can be increased when Butorphanol is combined with Nefazodone.
Nalbuphine Injection Nalbuphine Injection The risk or severity of serotonin syndrome can be increased when Nalbuphine is combined with Nefazodone.
Allopurinol Allopurinol Allopurinol may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Trimethobenzamide Trimethobenzamide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Nefazodone.
Flavoxate Flavoxate Flavoxate may increase the central nervous system depressant (CNS depressant) activities of Nefazodone.
Colchicine Colchicine The metabolism of Colchicine can be decreased when combined with Nefazodone.
Cefaclor Cefaclor Cefaclor may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Cefadroxil Cefadroxil Cefadroxil may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection Cefazolin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Cephalexin Cephalexin The metabolism of Cephalexin can be decreased when combined with Nefazodone.
Cefoxitin Injection Cefoxitin Injection Cefoxitin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Dacarbazine Dacarbazine Dacarbazine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Acetazolamide is combined with Nefazodone.
Cefotaxime Injection Cefotaxime Injection Cefotaxime may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Calcitonin Salmon Injection Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Ketoconazole Ketoconazole The metabolism of Nefazodone can be decreased when combined with Ketoconazole.
Pyrantel Pyrantel The risk or severity of adverse effects can be increased when Pyrantel is combined with Nefazodone.
Thiotepa Injection Thiotepa Injection The metabolism of Thiotepa can be decreased when combined with Nefazodone.
Vincristine Injection Vincristine Injection The metabolism of Nefazodone can be decreased when combined with Vincristine.
Captopril Captopril Nefazodone may decrease the antihypertensive activities of Captopril.
Dipyridamole Dipyridamole The risk or severity of hemorrhage can be increased when Dipyridamole is combined with Nefazodone.
Isoxsuprine Isoxsuprine The therapeutic efficacy of Isoxsuprine can be decreased when used in combination with Nefazodone.
Vinblastine Vinblastine The metabolism of Nefazodone can be decreased when combined with Vinblastine.
Ethacrynic Acid Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Colistimethate Injection Colistimethate Injection Colistimethate may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Metoprolol Metoprolol The metabolism of Metoprolol can be decreased when combined with Nefazodone.
Hydroxyzine Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Nefazodone.
Thiothixene Thiothixene The risk or severity of adverse effects can be increased when Nefazodone is combined with Thiothixene.
Aspirin Aspirin Nefazodone may increase the antiplatelet activities of Acetylsalicylic acid.
Salsalate Salsalate The risk or severity of gastrointestinal bleeding can be increased when Salsalate is combined with Nefazodone.
Alprazolam Alprazolam The metabolism of Alprazolam can be decreased when combined with Nefazodone.
Temazepam Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Nefazodone.
Triazolam Triazolam The risk or severity of adverse effects can be increased when Triazolam is combined with Nefazodone.
Dicyclomine Dicyclomine Dicyclomine may increase the central nervous system depressant (CNS depressant) activities of Nefazodone.
Hyoscyamine Hyoscyamine Nefazodone may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline Propantheline Propantheline may increase the central nervous system depressant (CNS depressant) activities of Nefazodone.
Trimethoprim Trimethoprim Trimethoprim may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Diltiazem Diltiazem The risk or severity of hypotension can be increased when Nefazodone is combined with Diltiazem.
Nifedipine Nifedipine The metabolism of Nefazodone can be decreased when combined with Nifedipine.
Timolol Timolol The metabolism of Timolol can be decreased when combined with Nefazodone.
Verapamil Verapamil Verapamil may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Atenolol Atenolol The serum concentration of Atenolol can be increased when it is combined with Nefazodone.
Pindolol Pindolol The risk or severity of adverse effects can be increased when Pindolol is combined with Nefazodone.
Cisplatin Injection Cisplatin Injection Nefazodone may decrease the excretion rate of Cisplatin which could result in a higher serum level.
Diflunisal Diflunisal The risk or severity of gastrointestinal bleeding can be increased when Diflunisal is combined with Nefazodone.
Piroxicam Piroxicam The risk or severity of gastrointestinal bleeding can be increased when Piroxicam is combined with Nefazodone.
Bumetanide Bumetanide Bumetanide may increase the excretion rate of Nefazodone which could result in a lower serum level and potentially a reduction in efficacy.
Etoposide Etoposide The metabolism of Etoposide can be decreased when combined with Nefazodone.
Glyburide Glyburide The risk or severity of hypoglycemia can be increased when Glyburide is combined with Nefazodone.
Glipizide Glipizide The risk or severity of hypoglycemia can be increased when Glipizide is combined with Nefazodone.
Indapamide Indapamide Nefazodone may increase the excretion rate of Indapamide which could result in a lower serum level and potentially a reduction in efficacy.
Amoxicillin Amoxicillin Amoxicillin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Oxacillin Injection Oxacillin Injection Oxacillin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Pentoxifylline Pentoxifylline The risk or severity of hypotension, dyspepsia, and headache can be increased when Pentoxifylline is combined with Nefazodone.
Pentamidine Injection Pentamidine Injection Nefazodone may decrease the excretion rate of Pentamidine which could result in a higher serum level.
Ceftriaxone Injection Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Labetalol Labetalol Labetalol may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Auranofin Auranofin Auranofin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection Leuprolide may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Gemfibrozil Gemfibrozil Nefazodone may decrease the excretion rate of Gemfibrozil which could result in a higher serum level.
Guanabenz Guanabenz The therapeutic efficacy of Guanabenz can be decreased when used in combination with Nefazodone.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Ceftazidime Injection Ceftazidime Injection Ceftazidime may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Ketoprofen Ketoprofen The risk or severity of gastrointestinal bleeding can be increased when Ketoprofen is combined with Nefazodone.
Cefotetan Injection Cefotetan Injection Cefotetan may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Pimozide Pimozide The risk or severity of QTc prolongation can be increased when Nefazodone is combined with Pimozide.
Enalapril Enalapril Nefazodone may decrease the antihypertensive activities of Enalapril.
Flurbiprofen Flurbiprofen The risk or severity of gastrointestinal bleeding can be increased when Flurbiprofen is combined with Nefazodone.
Amiodarone Amiodarone The metabolism of Amiodarone can be decreased when combined with Nefazodone.
Aztreonam Injection Aztreonam Injection Aztreonam may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Buspirone Buspirone The serum concentration of Buspirone can be increased when it is combined with Nefazodone.
Lovastatin Lovastatin The serum concentration of Lovastatin can be increased when it is combined with Nefazodone.
Ciprofloxacin Ciprofloxacin Ciprofloxacin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Mesalamine Mesalamine The risk or severity of gastrointestinal bleeding can be increased when Mesalazine is combined with Nefazodone.
Diclofenac Diclofenac The risk or severity of gastrointestinal bleeding can be increased when Nefazodone is combined with Diclofenac.
Fluoxetine Fluoxetine The serum concentration of Nefazodone can be increased when it is combined with Fluoxetine.
Nimodipine Nimodipine The risk or severity of hypotension can be increased when Nefazodone is combined with Nimodipine.
Clozapine Clozapine Clozapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Estazolam Estazolam The risk or severity of adverse effects can be increased when Nefazodone is combined with Estazolam.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Nefazodone.
Ofloxacin Ofloxacin Nefazodone may decrease the excretion rate of Ofloxacin which could result in a higher serum level.
Didanosine Didanosine Didanosine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Pentostatin Injection Pentostatin Injection Pentostatin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Clarithromycin Clarithromycin Nefazodone may decrease the excretion rate of Clarithromycin which could result in a higher serum level.
Benazepril Benazepril Nefazodone may decrease the antihypertensive activities of Benazepril.
Etodolac Etodolac The risk or severity of gastrointestinal bleeding can be increased when Etodolac is combined with Nefazodone.
Felodipine Felodipine The risk or severity of hypotension can be increased when Nefazodone is combined with Felodipine.
Fosinopril Fosinopril Fosinopril may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Nabumetone Nabumetone The risk or severity of gastrointestinal bleeding can be increased when Nabumetone is combined with Nefazodone.
Pravastatin Pravastatin Nefazodone may decrease the excretion rate of Pravastatin which could result in a higher serum level.
Quinapril Quinapril Nefazodone may decrease the antihypertensive activities of Quinapril.
Ramipril Ramipril Nefazodone may decrease the antihypertensive activities of Ramipril.
Simvastatin Simvastatin Nefazodone may decrease the excretion rate of Simvastatin which could result in a higher serum level.
Amlodipine Amlodipine The metabolism of Amlodipine can be decreased when combined with Nefazodone.
Teniposide Injection Teniposide Injection The metabolism of Teniposide can be decreased when combined with Nefazodone.
Lisinopril Lisinopril Lisinopril may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Oxaprozin Oxaprozin The risk or severity of gastrointestinal bleeding can be increased when Oxaprozin is combined with Nefazodone.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Nefazodone.
Bisoprolol Bisoprolol The serum concentration of Bisoprolol can be increased when it is combined with Nefazodone.
Zolpidem Zolpidem Nefazodone may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin Doxazosin The metabolism of Doxazosin can be decreased when combined with Nefazodone.
Terazosin Terazosin Nefazodone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Terazosin.
Isradipine Isradipine Nefazodone may decrease the excretion rate of Isradipine which could result in a higher serum level.
Omeprazole Omeprazole The metabolism of Nefazodone can be decreased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Nefazodone can be decreased when combined with Cisapride.
Gabapentin Gabapentin The risk or severity of adverse effects can be increased when Gabapentin is combined with Nefazodone.
Fluvastatin Fluvastatin The excretion of Fluvastatin can be decreased when combined with Nefazodone.
Venlafaxine Venlafaxine The metabolism of Nefazodone can be decreased when combined with Venlafaxine.
Famciclovir Famciclovir The metabolism of Famciclovir can be decreased when combined with Nefazodone.
Fluvoxamine Fluvoxamine The metabolism of Nefazodone can be decreased when combined with Fluvoxamine.
Lamotrigine Lamotrigine The risk or severity of adverse effects can be increased when Lamotrigine is combined with Nefazodone.
Losartan Losartan Losartan may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Valacyclovir Valacyclovir Valaciclovir may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Tramadol Tramadol The risk or severity of serotonin syndrome can be increased when Nefazodone is combined with Tramadol.
Vinorelbine Injection Vinorelbine Injection The metabolism of Nefazodone can be decreased when combined with Vinorelbine.
Carboplatin Injection Carboplatin Injection Carboplatin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Moexipril Moexipril Nefazodone may decrease the antihypertensive activities of Moexipril.
Lansoprazole Lansoprazole The metabolism of Nefazodone can be decreased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Nefazodone.
Nicardipine Nicardipine Nicardipine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Bupropion Bupropion The metabolism of Bupropion can be decreased when combined with Nefazodone.
Ticlopidine Ticlopidine The metabolism of Ticlopidine can be decreased when combined with Nefazodone.
Saquinavir Saquinavir Nefazodone may decrease the excretion rate of Saquinavir which could result in a higher serum level.
Metformin Metformin The risk or severity of hypoglycemia can be increased when Metformin is combined with Nefazodone.
Dalteparin Injection Dalteparin Injection The risk or severity of hemorrhage can be increased when Nefazodone is combined with Dalteparin.
Nisoldipine Nisoldipine The risk or severity of hypotension can be increased when Nefazodone is combined with Nisoldipine.
Lamivudine Lamivudine Lamivudine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Riluzole Riluzole The risk or severity of adverse effects can be increased when Riluzole is combined with Nefazodone.
Acarbose Acarbose The risk or severity of hypoglycemia can be increased when Acarbose is combined with Nefazodone.
Glimepiride Glimepiride Glimepiride may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Gemcitabine Injection Gemcitabine Injection Gemcitabine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Indinavir Indinavir Indinavir may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Ritonavir Ritonavir The serum concentration of Ritonavir can be increased when it is combined with Nefazodone.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Nefazodone.
Cidofovir Injection Cidofovir Injection Cidofovir may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Meropenem Injection Meropenem Injection Meropenem may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Clomipramine Clomipramine The metabolism of Nefazodone can be decreased when combined with Clomipramine.
Zafirlukast Zafirlukast The metabolism of Nefazodone can be decreased when combined with Zafirlukast.
Fosfomycin Fosfomycin Fosfomycin may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Mirtazapine Mirtazapine Nefazodone may increase the serotonergic activities of Mirtazapine.
Trandolapril Trandolapril Nefazodone may decrease the antihypertensive activities of Trandolapril.
Topiramate Topiramate The risk or severity of adverse effects can be increased when Nefazodone is combined with Topiramate.
Valsartan Valsartan The excretion of Valsartan can be decreased when combined with Nefazodone.
Insulin Lispro Injection Insulin Lispro Injection The risk or severity of hypoglycemia can be increased when Insulin lispro is combined with Nefazodone.
Pramipexole Pramipexole Nefazodone may increase the sedative activities of Pramipexole.
Donepezil Donepezil The risk or severity of adverse effects can be increased when Nefazodone is combined with Donepezil.
Nelfinavir Nelfinavir The metabolism of Nefazodone can be decreased when combined with Nelfinavir.
Fexofenadine Fexofenadine The excretion of Fexofenadine can be decreased when combined with Nefazodone.
Azithromycin Azithromycin The metabolism of Azithromycin can be decreased when combined with Nefazodone.
Loratadine Loratadine Loratadine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Carvedilol Carvedilol Carvedilol may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Nilutamide Nilutamide Nilutamide may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Flutamide Flutamide Flutamide may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Selegiline Selegiline Selegiline may increase the serotonergic activities of Nefazodone.
Bicalutamide Bicalutamide The metabolism of Nefazodone can be decreased when combined with Bicalutamide.
Sertraline Sertraline The risk or severity of adverse effects can be increased when Sertraline is combined with Nefazodone.
Propafenone Propafenone The metabolism of Propafenone can be decreased when combined with Nefazodone.
Raloxifene Raloxifene The excretion of Raloxifene can be decreased when combined with Nefazodone.
Irbesartan Irbesartan Nefazodone may decrease the antihypertensive activities of Irbesartan.
Tamsulosin Tamsulosin Tamsulosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Ropinirole Ropinirole Nefazodone may increase the sedative activities of Ropinirole.
Finasteride Finasteride The risk or severity of hypertension can be increased when Nefazodone is combined with Finasteride.
Quetiapine Quetiapine The serum concentration of Quetiapine can be increased when it is combined with Nefazodone.
Cefepime Injection Cefepime Injection Cefepime may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Cefprozil Cefprozil Cefprozil may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Cefpodoxime Cefpodoxime Cefpodoxime may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Cetirizine Cetirizine The risk or severity of adverse effects can be increased when Cetirizine is combined with Nefazodone.
Paroxetine Paroxetine The metabolism of Nefazodone can be decreased when combined with Paroxetine.
Tolcapone Tolcapone The risk or severity of adverse effects can be increased when Tolcapone is combined with Nefazodone.
Citalopram Citalopram The risk or severity of adverse effects can be increased when Citalopram is combined with Nefazodone.
Capecitabine Capecitabine Capecitabine may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Efavirenz Efavirenz The risk or severity of adverse effects can be increased when Efavirenz is combined with Nefazodone.
Abacavir Abacavir Abacavir may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Sildenafil Sildenafil The metabolism of Sildenafil can be decreased when combined with Nefazodone.
Pioglitazone Pioglitazone The risk or severity of hypoglycemia can be increased when Pioglitazone is combined with Nefazodone.
Celecoxib Celecoxib The risk or severity of bleeding can be increased when Celecoxib is combined with Nefazodone.
Rosiglitazone Rosiglitazone The metabolism of Nefazodone can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine The serum concentration of Tolterodine can be increased when it is combined with Nefazodone.
Thalidomide Thalidomide Nefazodone may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Oseltamivir Oseltamivir Oseltamivir may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Balsalazide Balsalazide The risk or severity of gastrointestinal bleeding can be increased when Balsalazide is combined with Nefazodone.
Nateglinide Nateglinide The risk or severity of hypoglycemia can be increased when Nateglinide is combined with Nefazodone.
Galantamine Galantamine The metabolism of Galantamine can be decreased when combined with Nefazodone.
Levetiracetam Levetiracetam The risk or severity of adverse effects can be increased when Nefazodone is combined with Levetiracetam.
Rabeprazole Rabeprazole Rabeprazole may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Terbinafine Terbinafine The metabolism of Terbinafine can be decreased when combined with Nefazodone.

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