Edoxaban

Generic name: Pronounced as (e dox' a ban)
Brand names
  • Savaysa®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 06/15/2020

If you have atrial fibrillation (a condition in which the heart beats irregularly, increasing the chance of clots forming in the body, and possibly causing strokes) and are taking edoxaban to help prevent strokes or serious blood clots, you are at a higher risk of having a stroke after you stop taking this medication. Do not stop taking edoxaban without talking to your doctor. Continue to take edoxaban even if you feel well. Be sure to refill your prescription before you run out of medication so that you will not miss any doses of edoxaban. If you need to stop taking edoxaban, your doctor may prescribe another anticoagulant (''blood thinner'') to help prevent a blood clot from forming and causing you to have a stroke.

If you have epidural or spinal anesthesia or a spinal puncture while taking a 'blood thinner' such as edoxaban, you are at risk of having a blood clot form in or around your spine that could cause you to become paralyzed. Tell your doctor if you have an epidural catheter that is left in your body or have or have ever had repeated epidural or spinal punctures, spinal deformity, or spinal surgery. Tell your doctor and pharmacist if you are taking anagrelide (Agrylin); aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others), indomethacin (Indocin, Tivorbex), ketoprofen, and naproxen (Aleve, Anaprox, others); cilostazol (Pletal); clopidogrel (Plavix); dipyridamole (Persantine); eptifibatide (Integrilin); heparin; prasugrel (Effient); ticagrelor (Brilinta); ticlopidine; tirofiban (Aggrastat), and warfarin (Coumadin, Jantoven). If you experience any of the following symptoms, call your doctor immediately: back pain, muscle weakness, numbness or tingling (especially in your legs), loss of control of your bowels or bladder, or inability to move your legs.

Keep all appointments with your doctor and the laboratory. Your doctor will order a test to check how well your kidneys are working before and periodically during your treatment with edoxaban.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with edoxaban and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/downloads/Drugs/DrugSafety/) or the manufacturer's website to obtain the Medication Guide.

Talk to your doctor about the risk of taking edoxaban.

Edoxaban is used help prevent strokes or blood clots in people who have atrial fibrillation (a condition in which the heart beats irregularly, increasing the chance of clots forming in the body and possibly causing strokes) that is not caused by heart valve disease. Edoxaban is also used to prevent deep vein thrombosis (DVT; a blood clot, usually in the leg) and pulmonary embolism (PE; a blood clot in the lung) in people who have been treated with an injectable blood thinner medicine for 5 to 10 days. Edoxaban is in a class of medications called factor Xa inhibitors. It works by blocking the action of a certain natural substance that helps blood clots to form.

Edoxaban comes as a tablet to take by mouth. It is usually taken with or without food once a day. Take edoxaban at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take edoxaban exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If you are unable to swallow the tablets, crush and mix them with 2 to 3 ounces (60 to 90 mL) of water or applesauce. Take the mixture immediately.

If you have a gastric tube, the tablets can be crushed and mixed in water and given through the tube. Ask your doctor or pharmacist how you should take the medication. Follow those directions carefully.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking edoxaban,

  • tell your doctor and pharmacist if you are allergic to edoxaban, any other medications, or any of the ingredients in edoxaban tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: amiodarone (Cordarone, Pacerone), atorvastatin (Lipitor, in Caduet, in Liptruzet), cyclosporine (Gengraf, Neoral), digoxin (Lanoxin), dronedarone (Multaq), erythromycin (E.E.S., E-Mycin, Erythrocin), esomeprazole (Nexium, in Vimovo), ketoconazole (Nizoral), quinidine, rifampin (Rifadin, in Rifamate, in Rifater, Rimactane), selective serotonin-reuptake inhibitors such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Selfemra), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), and sertraline (Zoloft); serotonin–norepinephrine reuptake inhibitors (SNRI) such as desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), levomilnacipran (Fetzima), milnacipran (Savella), and venlafaxine (Effexor); and verapamil (Calan, Covera, Isoptin, Verelan, in Tarka). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with edoxaban, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you have heavy bleeding anywhere in your body that cannot be stopped. Your doctor will probably tell you not to take edoxaban.

  • tell your doctor if you weigh 132 pounds (60 kilograms) or less and if you have or have ever had any type of bleeding problem, a mechanical heart valve, antiphospholipid syndrome (an autoimmune disorder that causes blood clots), cancer of the stomach or intestine, or heart, kidney or liver disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking edoxaban, call your doctor.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking edoxaban.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it on the same day. However, if it is the next day, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Edoxaban may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • rash

    • unusual tiredness or weakness

    • dizziness

    • pale skin

  • Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, stop taking edoxaban and call your doctor immediately:

    • bleeding gums

    • nosebleeds

    • heavy vaginal bleeding

    • red, pink, or brown urine

    • red or black, tarry stools

    • coughing up or vomiting blood or material that looks like coffee grounds

  • Edoxaban may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

  • unusual bleeding or bruising

  • bloody, black, or tarry stools

  • blood in urine

  • coughing up or vomiting blood or material that looks like coffee grounds

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking edoxaban.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Anagrelide Anagrelide The risk or severity of bleeding can be increased when Anagrelide is combined with Edoxaban.
Calcium Carbonate Calcium Carbonate The therapeutic efficacy of Calcium carbonate can be decreased when used in combination with Edoxaban.
Cilostazol Cilostazol The risk or severity of bleeding can be increased when Cilostazol is combined with Edoxaban.
Clopidogrel Clopidogrel The risk or severity of bleeding can be increased when Clopidogrel is combined with Edoxaban.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The serum concentration of Edoxaban can be increased when it is combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Conjugated estrogens may decrease the anticoagulant activities of Edoxaban.
Fenofibrate Fenofibrate Fenofibrate may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Guanfacine Guanfacine Guanfacine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Magnesium Hydroxide Magnesium Hydroxide Edoxaban may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Mycophenolate Mycophenolate Mycophenolic acid may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Olsalazine Olsalazine The risk or severity of bleeding and hemorrhage can be increased when Olsalazine is combined with Edoxaban.
Paregoric Paregoric The serum concentration of Edoxaban can be increased when it is combined with Morphine.
Potassium Potassium Potassium cation may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone Prednisone Prednisone may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ranitidine Ranitidine Ranitidine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Reserpine Reserpine The serum concentration of Edoxaban can be increased when it is combined with Reserpine.
Rizatriptan Rizatriptan Rizatriptan may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Sumatriptan Sumatriptan Sumatriptan may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Tacrolimus Tacrolimus The serum concentration of Edoxaban can be increased when it is combined with Tacrolimus.
Triamcinolone Triamcinolone The therapeutic efficacy of Edoxaban can be decreased when used in combination with Triamcinolone.
Ampicillin Injection Ampicillin Injection Ampicillin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection The risk or severity of bleeding can be increased when Doxycycline is combined with Edoxaban.
Fluconazole Injection Fluconazole Injection The serum concentration of Edoxaban can be increased when it is combined with Fluconazole.
Foscarnet Injection Foscarnet Injection Foscarnet may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Hydromorphone Injection Hydromorphone Injection Hydromorphone may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Interferon Beta-1b Injection Interferon Beta-1b Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Interferon beta-1b.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Interferon gamma-1b.
Levofloxacin Injection Levofloxacin Injection Levofloxacin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Meperidine Injection Meperidine Injection Meperidine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Metoclopramide Injection Metoclopramide Injection Metoclopramide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Morphine Injection Morphine Injection The serum concentration of Edoxaban can be increased when it is combined with Morphine.
Pamidronate Injection Pamidronate Injection Pamidronic acid may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Vancomycin Injection Vancomycin Injection Edoxaban may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Zidovudine Injection Zidovudine Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Zidovudine.
Altretamine Altretamine The risk or severity of bleeding and hemorrhage can be increased when Amphetamine is combined with Edoxaban.
Cefuroxime Cefuroxime Cefuroxime may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Cyclosporine Cyclosporine The serum concentration of Cyclosporine can be increased when it is combined with Edoxaban.
Enoxaparin Injection Enoxaparin Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Enoxaparin.
Torsemide Torsemide Torasemide may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Meloxicam Meloxicam The risk or severity of bleeding and hemorrhage can be increased when Meloxicam is combined with Edoxaban.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Temozolomide Temozolomide Temozolomide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Zaleplon Zaleplon Zaleplon may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Linezolid Linezolid The risk or severity of bleeding and hemorrhage can be increased when Linezolid is combined with Edoxaban.
Pentosan Polysulfate Pentosan Polysulfate The risk or severity of bleeding can be increased when Edoxaban is combined with Pentosan polysulfate.
Trimipramine Trimipramine The serum concentration of Trimipramine can be increased when it is combined with Edoxaban.
Perindopril Perindopril Perindopril may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Tenofovir Tenofovir The serum concentration of Tenofovir can be increased when it is combined with Edoxaban.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate The risk or severity of bleeding and hemorrhage can be increased when Choline magnesium trisalicylate is combined with Edoxaban.
Sirolimus Sirolimus The serum concentration of Sirolimus can be increased when it is combined with Edoxaban.
Epirubicin Epirubicin The risk or severity of bleeding can be increased when Edoxaban is combined with Epirubicin.
Eplerenone Eplerenone Eplerenone may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Escitalopram Escitalopram The risk or severity of bleeding can be increased when Escitalopram is combined with Edoxaban.
Zonisamide Zonisamide The serum concentration of Edoxaban can be increased when it is combined with Zonisamide.
Atomoxetine Atomoxetine Atomoxetine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Atazanavir Atazanavir Atazanavir may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Almotriptan Almotriptan Almotriptan may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Vardenafil Vardenafil The serum concentration of Edoxaban can be increased when it is combined with Vardenafil.
Emtricitabine Emtricitabine Emtricitabine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Memantine Memantine Memantine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Tegaserod Tegaserod The serum concentration of Edoxaban can be increased when it is combined with Tegaserod.
Tadalafil Tadalafil Tadalafil may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Progesterone Progesterone The therapeutic efficacy of Edoxaban can be decreased when used in combination with Progesterone.
Duloxetine Duloxetine The risk or severity of hemorrhage can be increased when Duloxetine is combined with Edoxaban.
Norethindrone Norethindrone Norethisterone may decrease the anticoagulant activities of Edoxaban.
Tinidazole Tinidazole Tinidazole may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Cefditoren Cefditoren Cefdinir may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Cyanocobalamin Injection Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Eszopiclone Eszopiclone Eszopiclone may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ganciclovir Ganciclovir Ganciclovir may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ribavirin Ribavirin Ribavirin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Valganciclovir Valganciclovir Valganciclovir may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Adefovir Adefovir Adefovir may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Dextroamphetamine Dextroamphetamine The risk or severity of bleeding and hemorrhage can be increased when Amphetamine is combined with Edoxaban.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Peginterferon alfa-2a.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The risk or severity of bleeding can be increased when Edoxaban is combined with Peginterferon alfa-2b.
Isocarboxazid Isocarboxazid The risk or severity of bleeding and hemorrhage can be increased when Isocarboxazid is combined with Edoxaban.
Ramelteon Ramelteon Ramelteon may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Fentanyl Fentanyl Fentanyl may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Pregabalin Pregabalin Pregabalin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Deferasirox Deferasirox The risk or severity of gastrointestinal bleeding can be increased when Edoxaban is combined with Deferasirox.
Tipranavir Tipranavir The serum concentration of Edoxaban can be increased when it is combined with Tipranavir.
Ranolazine Ranolazine The serum concentration of Edoxaban can be increased when it is combined with Ranolazine.
Rasagiline Rasagiline The risk or severity of bleeding and hemorrhage can be increased when Rasagiline is combined with Edoxaban.
Imatinib Imatinib The risk or severity of bleeding can be increased when Edoxaban is combined with Imatinib.
Sitagliptin Sitagliptin The serum concentration of Edoxaban can be increased when it is combined with Sitagliptin.
Varenicline Varenicline Varenicline may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Albuterol Albuterol Salbutamol may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Paliperidone Paliperidone The serum concentration of Edoxaban can be increased when it is combined with Paliperidone.
Bortezomib Bortezomib The serum concentration of Bortezomib can be increased when it is combined with Edoxaban.
Clofarabine Injection Clofarabine Injection Clofarabine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Lubiprostone Lubiprostone Lubiprostone may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Oxaliplatin.
Posaconazole Posaconazole The serum concentration of Edoxaban can be increased when it is combined with Posaconazole.
Rituximab Injection Rituximab Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Rituximab.
Bismuth Subsalicylate Bismuth Subsalicylate The risk or severity of bleeding can be increased when Bismuth subsalicylate is combined with Edoxaban.
Pemetrexed Injection Pemetrexed Injection Edoxaban may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Vorinostat Vorinostat The risk or severity of bleeding can be increased when Edoxaban is combined with Vorinostat.
Sorafenib Sorafenib The serum concentration of Edoxaban can be increased when it is combined with Sorafenib.
Lapatinib Lapatinib The serum concentration of Edoxaban can be increased when it is combined with Lapatinib.
Levocetirizine Levocetirizine Levocetirizine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Pegaptanib Injection Pegaptanib Injection Pegaptanib may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Dasatinib Dasatinib The risk or severity of bleeding and hemorrhage can be increased when Dasatinib is combined with Edoxaban.
Omega-3 Fatty Acids Omega-3 Fatty Acids Omega-3 fatty acids may increase the anticoagulant activities of Edoxaban.
Azacitidine Injection Azacitidine Injection Azacitidine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Temsirolimus Temsirolimus The serum concentration of Edoxaban can be increased when it is combined with Temsirolimus.
Nelarabine Injection Nelarabine Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Nelarabine.
Lenalidomide Lenalidomide Lenalidomide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Nilotinib Nilotinib The serum concentration of Edoxaban can be increased when it is combined with Nilotinib.
Toremifene Toremifene The serum concentration of Edoxaban can be increased when it is combined with Toremifene.
Bexarotene Bexarotene The risk or severity of bleeding can be increased when Edoxaban is combined with Bexarotene.
Budesonide Budesonide Budesonide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Chloramphenicol Injection Chloramphenicol Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Chloramphenicol.
Decitabine Injection Decitabine Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Decitabine.
Desmopressin Desmopressin Desmopressin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Doripenem Injection Doripenem Injection Doripenem may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Arsenic Trioxide Injection Arsenic Trioxide Injection Arsenic trioxide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Mitoxantrone Injection Mitoxantrone Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Mitoxantrone.
Desvenlafaxine Desvenlafaxine The risk or severity of hemorrhage can be increased when Desvenlafaxine is combined with Edoxaban.
Cevimeline Cevimeline Cevimeline may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Bendamustine Injection Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Edoxaban.
Certolizumab Injection Certolizumab Injection Certolizumab pegol may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ixabepilone Injection Ixabepilone Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Ixabepilone.
Irinotecan Injection Irinotecan Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Irinotecan.
Daptomycin Injection Daptomycin Injection Daptomycin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Methylnaltrexone Injection Methylnaltrexone Injection Methylnaltrexone may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of bleeding can be increased when Edoxaban is combined with Alemtuzumab.
Silodosin Silodosin The serum concentration of Edoxaban can be increased when it is combined with Silodosin.
Midazolam Midazolam Midazolam may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Dexrazoxane Injection Dexrazoxane Injection Dexrazoxane may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ibritumomab Injection Ibritumomab Injection The risk or severity of adverse effects can be increased when Edoxaban is combined with Ibritumomab tiuxetan.
Milnacipran Milnacipran The risk or severity of hemorrhage can be increased when Milnacipran is combined with Edoxaban.
Plerixafor Injection Plerixafor Injection Plerixafor may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Fesoterodine Fesoterodine Fesoterodine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Prasugrel Prasugrel The risk or severity of bleeding can be increased when Edoxaban is combined with Prasugrel.
Everolimus Everolimus The serum concentration of Edoxaban can be increased when it is combined with Everolimus.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The serum concentration of Edoxaban can be increased when it is combined with Tolvaptan.
Dronedarone Dronedarone The serum concentration of Edoxaban can be increased when it is combined with Dronedarone.
Pralatrexate Injection Pralatrexate Injection Pralatrexate may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection Palonosetron may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Saxagliptin Saxagliptin Saxagliptin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Telavancin Injection Telavancin Injection Telavancin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Romidepsin Injection Romidepsin Injection The serum concentration of Edoxaban can be increased when it is combined with Romidepsin.
Topotecan Topotecan The serum concentration of Edoxaban can be increased when it is combined with Topotecan.
Pazopanib Pazopanib The serum concentration of Edoxaban can be increased when it is combined with Pazopanib.
Ulipristal Ulipristal The therapeutic efficacy of Edoxaban can be decreased when used in combination with Ulipristal.
Levonorgestrel Levonorgestrel Levonorgestrel may decrease the anticoagulant activities of Edoxaban.
Dabigatran Dabigatran The risk or severity of bleeding can be increased when Edoxaban is combined with Dabigatran.
Dalfampridine Dalfampridine Dalfampridine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Eribulin Injection Eribulin Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Eribulin.
Cabazitaxel Injection Cabazitaxel Injection The serum concentration of Edoxaban can be increased when it is combined with Cabazitaxel.
Ceftaroline Injection Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Acetaminophen Injection Acetaminophen Injection Acetaminophen may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ipilimumab Injection Ipilimumab Injection Ipilimumab may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection Aldesleukin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Terbutaline Injection Terbutaline Injection Terbutaline may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Busulfan Injection Busulfan Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Busulfan.
Roflumilast Roflumilast Roflumilast may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Linagliptin Linagliptin The serum concentration of Edoxaban can be increased when it is combined with Linagliptin.
Telaprevir Telaprevir The serum concentration of Edoxaban can be increased when it is combined with Glecaprevir.
Potassium Iodide Potassium Iodide Potassium Iodide may increase the anticoagulant activities of Edoxaban.
Cyclophosphamide Injection Cyclophosphamide Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Cyclophosphamide.
Rivaroxaban Rivaroxaban The risk or severity of bleeding can be increased when Edoxaban is combined with Rivaroxaban.
Ticagrelor Ticagrelor The risk or severity of bleeding can be increased when Edoxaban is combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The serum concentration of Brentuximab vedotin can be increased when it is combined with Edoxaban.
Ruxolitinib Ruxolitinib Ruxolitinib may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Vandetanib Vandetanib The serum concentration of Edoxaban can be increased when it is combined with Vandetanib.
Clobazam Clobazam The serum concentration of Edoxaban can be increased when it is combined with Clobazam.
Vemurafenib Vemurafenib The serum concentration of Edoxaban can be increased when it is combined with Vemurafenib.
Ivacaftor Ivacaftor The serum concentration of Edoxaban can be increased when it is combined with Ivacaftor.
Deferiprone Deferiprone Deferiprone may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Axitinib Axitinib The serum concentration of Axitinib can be increased when it is combined with Edoxaban.
Crizotinib Crizotinib The serum concentration of Edoxaban can be increased when it is combined with Crizotinib.
Melphalan Injection Melphalan Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Melphalan.
Cabergoline Cabergoline The serum concentration of Cabergoline can be increased when it is combined with Edoxaban.
Naloxone Injection Naloxone Injection Naloxone may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ambrisentan Ambrisentan The serum concentration of Edoxaban can be increased when it is combined with Ambrisentan.
Fondaparinux Injection Fondaparinux Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Fondaparinux.
Collagenase Clostridium Histolyticum Injection Collagenase Clostridium Histolyticum Injection The risk or severity of adverse effects can be increased when Edoxaban is combined with Collagenase clostridium histolyticum.
Carfilzomib Injection Carfilzomib Injection The serum concentration of Edoxaban can be increased when it is combined with Carfilzomib.
Iloprost Iloprost The risk or severity of bleeding can be increased when Edoxaban is combined with Iloprost.
Enzalutamide Enzalutamide The serum concentration of Edoxaban can be increased when it is combined with Enzalutamide.
Mirabegron Mirabegron The serum concentration of Edoxaban can be increased when it is combined with Mirabegron.
Regorafenib Regorafenib The serum concentration of Edoxaban can be increased when it is combined with Regorafenib.
Bosutinib Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Edoxaban.
Teduglutide Injection Teduglutide Injection Teduglutide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Icosapent Ethyl Icosapent Ethyl The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Edoxaban.
Tofacitinib Tofacitinib The risk or severity of bleeding can be increased when Edoxaban is combined with Tofacitinib.
Alogliptin Alogliptin Alogliptin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ponatinib Ponatinib The serum concentration of Edoxaban can be increased when it is combined with Ponatinib.
Pomalidomide Pomalidomide The serum concentration of Edoxaban can be increased when it is combined with Pomalidomide.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The serum concentration of Edoxaban can be increased when it is combined with Trastuzumab emtansine.
Apixaban Apixaban Apixaban may increase the anticoagulant activities of Edoxaban.
Canagliflozin Canagliflozin The serum concentration of Edoxaban can be increased when it is combined with Canagliflozin.
Methazolamide Methazolamide Methazolamide may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Dabrafenib Dabrafenib The serum concentration of Edoxaban can be increased when it is combined with Dabrafenib.
Trametinib Trametinib Trametinib may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Dolutegravir Dolutegravir The serum concentration of Edoxaban can be increased when it is combined with Dolutegravir.
Afatinib Afatinib The serum concentration of Edoxaban can be increased when it is combined with Afatinib.
Levomilnacipran Levomilnacipran The risk or severity of hemorrhage can be increased when Levomilnacipran is combined with Edoxaban.
Ertapenem Injection Ertapenem Injection Ertapenem may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Vortioxetine Vortioxetine Vortioxetine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ibrutinib Ibrutinib The risk or severity of bleeding and hemorrhage can be increased when Ibrutinib is combined with Edoxaban.
Lomitapide Lomitapide The serum concentration of Edoxaban can be increased when it is combined with Lomitapide.
Ketorolac Injection Ketorolac Injection The risk or severity of bleeding and hemorrhage can be increased when Ketorolac is combined with Edoxaban.
Obinutuzumab Injection Obinutuzumab Injection The risk or severity of bleeding and hemorrhage can be increased when Edoxaban is combined with Obinutuzumab.
Simeprevir Simeprevir The serum concentration of Edoxaban can be increased when it is combined with Simeprevir.
Sofosbuvir Sofosbuvir The serum concentration of Edoxaban can be increased when it is combined with Sofosbuvir.
Dapagliflozin Dapagliflozin Dapagliflozin may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Apremilast Apremilast Apremilast may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Droxidopa Droxidopa Droxidopa may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ceritinib Ceritinib The serum concentration of Edoxaban can be increased when it is combined with Ceritinib.
Belinostat Injection Belinostat Injection The serum concentration of Edoxaban can be increased when it is combined with Belinostat.
Idelalisib Idelalisib The serum concentration of Edoxaban can be increased when it is combined with Idelalisib.
Testosterone Injection Testosterone Injection Testosterone may increase the anticoagulant activities of Edoxaban.
Vorapaxar Vorapaxar The risk or severity of bleeding can be increased when Edoxaban is combined with Vorapaxar.
Suvorexant Suvorexant The serum concentration of Edoxaban can be increased when it is combined with Suvorexant.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Peginterferon beta-1a.
Olaparib Olaparib The risk or severity of bleeding can be increased when Edoxaban is combined with Olaparib.
Blinatumomab Injection Blinatumomab Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Blinatumomab.
Methamphetamine Methamphetamine Metamfetamine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Tasimelteon Tasimelteon Tasimelteon may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Nintedanib Nintedanib The risk or severity of bleeding can be increased when Edoxaban is combined with Nintedanib.
Palbociclib Palbociclib The serum concentration of Edoxaban can be increased when it is combined with Palbociclib.
Lenvatinib Lenvatinib The serum concentration of Lenvatinib can be increased when it is combined with Edoxaban.
Panobinostat Panobinostat The serum concentration of Edoxaban can be increased when it is combined with Panobinostat.
Dinutuximab Injection Dinutuximab Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Dinutuximab.
Haloperidol Injection Haloperidol Injection Haloperidol may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Deoxycholic Acid Injection Deoxycholic Acid Injection The risk or severity of bleeding and bruising can be increased when Edoxaban is combined with Deoxycholic acid.
Amiloride Amiloride Amiloride may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Isavuconazonium Injection Isavuconazonium Injection The serum concentration of Edoxaban can be increased when it is combined with Isavuconazonium.
Macitentan Macitentan Macitentan may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Flibanserin Flibanserin The serum concentration of Edoxaban can be increased when it is combined with Flibanserin.
Rolapitant Rolapitant The serum concentration of Edoxaban can be increased when it is combined with Rolapitant.
Daclatasvir Daclatasvir The serum concentration of Edoxaban can be increased when it is combined with Daclatasvir.
Penicillin G Procaine Injection Penicillin G Procaine Injection Edoxaban may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Cobimetinib Cobimetinib The serum concentration of Edoxaban can be increased when it is combined with Cobimetinib.
Trabectedin Injection Trabectedin Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Trabectedin.
Osimertinib Osimertinib The serum concentration of Osimertinib can be increased when it is combined with Edoxaban.
Ixazomib Ixazomib Edoxaban may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lesinurad Lesinurad Edoxaban may decrease the excretion rate of Lesinurad which could result in a higher serum level.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Defibrotide Injection Defibrotide Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Defibrotide.
Brivaracetam Injection Brivaracetam Injection Brivaracetam may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Venetoclax Venetoclax The serum concentration of Edoxaban can be increased when it is combined with Venetoclax.
Cobicistat Cobicistat The serum concentration of Edoxaban can be increased when it is combined with Cobicistat.
Selexipag Selexipag The serum concentration of Selexipag can be increased when it is combined with Edoxaban.
Obeticholic Acid Obeticholic Acid The risk or severity of bleeding and bruising can be increased when Edoxaban is combined with Obeticholic acid.
Furosemide Injection Furosemide Injection Furosemide may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Rucaparib Rucaparib The serum concentration of Edoxaban can be increased when it is combined with Rucaparib.
Lixisenatide Injection Lixisenatide Injection Edoxaban may decrease the excretion rate of Lixisenatide which could result in a higher serum level.
Doxepin (Insomnia) Doxepin (Insomnia) Doxepin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Deutetrabenazine Deutetrabenazine Edoxaban may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level.
Valbenazine Valbenazine Edoxaban may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Safinamide Safinamide The risk or severity of bleeding and hemorrhage can be increased when Safinamide is combined with Edoxaban.
Naldemedine Naldemedine Edoxaban may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Neratinib Neratinib The serum concentration of Edoxaban can be increased when it is combined with Neratinib.
Enasidenib Enasidenib The serum concentration of Edoxaban can be increased when it is combined with Enasidenib.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The serum concentration of Edoxaban can be increased when it is combined with Inotuzumab ozogamicin.
Benznidazole Benznidazole Edoxaban may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Copanlisib Injection Copanlisib Injection The serum concentration of Copanlisib can be increased when it is combined with Edoxaban.
Delafloxacin Delafloxacin Edoxaban may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Abemaciclib Abemaciclib The serum concentration of Abemaciclib can be increased when it is combined with Edoxaban.
Betrixaban Betrixaban The risk or severity of bleeding can be increased when Edoxaban is combined with Betrixaban.
Gemtuzumab Ozogamicin Injection Gemtuzumab Ozogamicin Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Gemtuzumab ozogamicin.
Ertugliflozin Ertugliflozin The serum concentration of Ertugliflozin can be increased when it is combined with Edoxaban.
Apalutamide Apalutamide The serum concentration of Edoxaban can be decreased when it is combined with Apalutamide.
Penicillamine Penicillamine The risk or severity of bleeding can be increased when Edoxaban is combined with Penicillamine.
Avatrombopag Avatrombopag The serum concentration of Avatrombopag can be increased when it is combined with Edoxaban.
Baricitinib Baricitinib The serum concentration of Baricitinib can be increased when it is combined with Edoxaban.
Lofexidine Lofexidine Lofexidine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Plazomicin Injection Plazomicin Injection Edoxaban may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Eliglustat Eliglustat The serum concentration of Edoxaban can be increased when it is combined with Eliglustat.
Binimetinib Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Edoxaban.
Ivosidenib Ivosidenib The serum concentration of Edoxaban can be increased when it is combined with Ivosidenib.
Lusutrombopag Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Edoxaban.
Elagolix Elagolix The serum concentration of Elagolix can be increased when it is combined with Edoxaban.
Dacomitinib Dacomitinib The serum concentration of Edoxaban can be increased when it is combined with Dacomitinib.
Duvelisib Duvelisib The serum concentration of Duvelisib can be increased when it is combined with Edoxaban.
Omadacycline Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Edoxaban.
Sarecycline Sarecycline The serum concentration of Edoxaban can be increased when it is combined with Sarecycline.
Stiripentol Stiripentol Edoxaban may decrease the excretion rate of Stiripentol which could result in a higher serum level.
Talazoparib Talazoparib The serum concentration of Talazoparib can be increased when it is combined with Edoxaban.
Gilteritinib Gilteritinib The serum concentration of Gilteritinib can be increased when it is combined with Edoxaban.
Glasdegib Glasdegib The serum concentration of Edoxaban can be increased when it is combined with Glasdegib.
Larotrectinib Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Edoxaban.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Paclitaxel.
Rifamycin Rifamycin The serum concentration of Edoxaban can be increased when it is combined with Rifamycin.
Prucalopride Prucalopride Prucalopride may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Acyclovir Ophthalmic Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Caplacizumab-yhdp Injection Caplacizumab-yhdp Injection The risk or severity of bleeding can be increased when Caplacizumab is combined with Edoxaban.
Erdafitinib Erdafitinib The serum concentration of Edoxaban can be increased when it is combined with Erdafitinib.
Cladribine Cladribine The risk or severity of bleeding can be increased when Edoxaban is combined with Cladribine.
Solriamfetol Solriamfetol Edoxaban may decrease the excretion rate of Solriamfetol which could result in a higher serum level.
Darolutamide Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Edoxaban.
Entrectinib Entrectinib The serum concentration of Edoxaban can be increased when it is combined with Entrectinib.
Istradefylline Istradefylline The serum concentration of Edoxaban can be increased when it is combined with Istradefylline.
Pitolisant Pitolisant The serum concentration of Edoxaban can be increased when it is combined with Pitolisant.
Fedratinib Fedratinib The serum concentration of Edoxaban can be increased when it is combined with Fedratinib.
Lefamulin Lefamulin The serum concentration of Lefamulin can be increased when it is combined with Edoxaban.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Edoxaban.
Lasmiditan Lasmiditan The serum concentration of Edoxaban can be increased when it is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Edoxaban.
Calcium Acetate Calcium Acetate The therapeutic efficacy of Calcium acetate can be decreased when used in combination with Edoxaban.
Tazemetostat Tazemetostat The serum concentration of Tazemetostat can be increased when it is combined with Edoxaban.
Selumetinib Selumetinib The serum concentration of Selumetinib can be increased when it is combined with Edoxaban.
Rimegepant Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Edoxaban.
Tucatinib Tucatinib Edoxaban may decrease the excretion rate of Tucatinib which could result in a higher serum level.
Remdesivir Injection Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Edoxaban.
Ripretinib Ripretinib The serum concentration of Edoxaban can be increased when it is combined with Ripretinib.
Lemborexant Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Edoxaban.
Fostemsavir Fostemsavir The serum concentration of Fostemsavir can be increased when it is combined with Edoxaban.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Edoxaban.
Pralsetinib Pralsetinib The serum concentration of Edoxaban can be increased when it is combined with Pralsetinib.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives Drospirenone may decrease the anticoagulant activities of Edoxaban.
Viloxazine Viloxazine Edoxaban may decrease the excretion rate of Viloxazine which could result in a higher serum level.
Vitamin E (Alpha-Tocopherol) Vitamin E (Alpha-Tocopherol) Vitamin E may increase the anticoagulant activities of Edoxaban.
Tobramycin Injection Tobramycin Injection Tobramycin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Fenoprofen Fenoprofen The risk or severity of bleeding and hemorrhage can be increased when Fenoprofen is combined with Edoxaban.
Indomethacin Indomethacin The risk or severity of bleeding and hemorrhage can be increased when Indomethacin is combined with Edoxaban.
Mefenamic Acid Mefenamic Acid The risk or severity of bleeding and hemorrhage can be increased when Mefenamic acid is combined with Edoxaban.
Naproxen Naproxen The risk or severity of bleeding and hemorrhage can be increased when Naproxen is combined with Edoxaban.
Tolmetin Tolmetin The risk or severity of bleeding and hemorrhage can be increased when Tolmetin is combined with Edoxaban.
Sulindac Sulindac The risk or severity of bleeding and hemorrhage can be increased when Sulindac is combined with Edoxaban.
Trazodone Trazodone The risk or severity of bleeding can be increased when Trazodone is combined with Edoxaban.
Isotretinoin Isotretinoin Isotretinoin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Sucralfate Sucralfate Sucralfate may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Hydroxyurea Hydroxyurea The risk or severity of bleeding can be increased when Edoxaban is combined with Hydroxyurea.
Floxuridine Floxuridine Floxuridine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Metaxalone Metaxalone Metaxalone may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Methotrexate Injection Methotrexate Injection Methotrexate may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Chlorpromazine Chlorpromazine Chlorpromazine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Diazepam Diazepam Diazepam may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Oxazepam Oxazepam Oxazepam may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Flurazepam Flurazepam Flurazepam may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Clorazepate Clorazepate Clorazepic acid may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Lorazepam Lorazepam Lorazepam may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Carmustine Carmustine Carmustine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Amantadine Amantadine Amantadine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Codeine Codeine Codeine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Tranylcypromine Tranylcypromine The risk or severity of bleeding and hemorrhage can be increased when Tranylcypromine is combined with Edoxaban.
Phenelzine Phenelzine The risk or severity of bleeding and hemorrhage can be increased when Phenelzine is combined with Edoxaban.
Procarbazine Procarbazine The risk or severity of bleeding and hemorrhage can be increased when Procarbazine is combined with Edoxaban.
Tetracycline Tetracycline Tetracycline may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Thioguanine Thioguanine The risk or severity of bleeding can be increased when Edoxaban is combined with Tioguanine.
Bleomycin Bleomycin Bleomycin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Sulfadiazine Sulfadiazine Sulfadiazine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Methadone Methadone Methadone may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Benztropine Benztropine Benzatropine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Maprotiline Maprotiline Maprotiline may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ibuprofen Ibuprofen Ibuprofen may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Azathioprine Azathioprine Azathioprine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Methylphenidate Methylphenidate Methylphenidate may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Sulfasalazine Sulfasalazine The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Edoxaban.
Lomustine Lomustine The risk or severity of bleeding can be increased when Edoxaban is combined with Lomustine.
Doxorubicin Doxorubicin The risk or severity of bleeding can be increased when Edoxaban is combined with Doxorubicin.
Cytarabine Cytarabine The risk or severity of bleeding can be increased when Edoxaban is combined with Cytarabine.
Mechlorethamine Mechlorethamine The risk or severity of bleeding can be increased when Edoxaban is combined with Mechlorethamine.
Dactinomycin Dactinomycin The serum concentration of Edoxaban can be increased when it is combined with Dactinomycin.
Phenazopyridine Phenazopyridine Phenazopyridine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Carbamazepine Carbamazepine Edoxaban may decrease the excretion rate of Carbamazepine which could result in a higher serum level.
Methyldopa Methyldopa Methyldopa may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Hydralazine Hydralazine Hydralazine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Cimetidine Cimetidine Cimetidine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Gentamicin Injection Gentamicin Injection Gentamicin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Warfarin Warfarin The risk or severity of bleeding can be increased when Edoxaban is combined with Warfarin.
Clonazepam Clonazepam Clonazepam may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Loperamide Loperamide The serum concentration of Edoxaban can be increased when it is combined with Loperamide.
Promethazine Promethazine Promethazine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Meclofenamate Meclofenamate The risk or severity of bleeding and hemorrhage can be increased when Meclofenamic acid is combined with Edoxaban.
Daunorubicin Daunorubicin The risk or severity of bleeding can be increased when Edoxaban is combined with Daunorubicin.
Nitrofurantoin Nitrofurantoin Nitrofurantoin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Digoxin Digoxin Edoxaban may decrease the excretion rate of Digoxin which could result in a higher serum level.
Loxapine Loxapine The serum concentration of Edoxaban can be increased when it is combined with Loxapine.
Chloroquine Chloroquine Chloroquine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Quinine Quinine The serum concentration of Edoxaban can be increased when it is combined with Quinine.
Triamterene Triamterene Triamterene may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Sulfinpyrazone Sulfinpyrazone The risk or severity of bleeding can be increased when Sulfinpyrazone is combined with Edoxaban.
Chlorothiazide Chlorothiazide Chlorothiazide may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Chlorthalidone Chlorthalidone Chlorthalidone may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Metolazone Metolazone Metolazone may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Isosorbide Isosorbide The therapeutic efficacy of Edoxaban can be decreased when used in combination with Isosorbide.
Secobarbital Secobarbital Secobarbital may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Desipramine Desipramine Desipramine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Amitriptyline Amitriptyline Amitriptyline may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Imipramine Imipramine The serum concentration of Edoxaban can be increased when it is combined with Imipramine.
Probenecid Probenecid Probenecid may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Quinidine Quinidine The serum concentration of Edoxaban can be increased when it is combined with Quinidine.
Procainamide Procainamide Edoxaban may decrease the excretion rate of Procainamide which could result in a higher serum level.
Isoniazid Isoniazid Isoniazid may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Pyrazinamide Pyrazinamide Pyrazinamide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Disopyramide Disopyramide Disopyramide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Tamoxifen Tamoxifen The serum concentration of Edoxaban can be increased when it is combined with Tamoxifen.
Mitomycin Mitomycin The risk or severity of bleeding can be increased when Edoxaban is combined with Mitomycin.
Butabarbital Butabarbital Butabarbital may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Liothyronine Liothyronine Liothyronine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Methimazole Methimazole Methimazole may increase the anticoagulant activities of Edoxaban.
Propylthiouracil Propylthiouracil Propylthiouracil may increase the anticoagulant activities of Edoxaban.
Chlorpropamide Chlorpropamide Chlorpropamide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Tolbutamide Tolbutamide Tolbutamide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Tolazamide Tolazamide Tolazamide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Baclofen Baclofen Baclofen may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ethambutol Ethambutol Ethambutol may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Methyclothiazide Methyclothiazide Methyclothiazide may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Hydrochlorothiazide Hydrochlorothiazide Hydrochlorothiazide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Chlorzoxazone Chlorzoxazone Chlorzoxazone may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Pyridoxine Pyridoxine Pyridoxine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Folic Acid Folic Acid Folic acid may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) Propranolol may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Nortriptyline Nortriptyline The serum concentration of Nortriptyline can be increased when it is combined with Edoxaban.
Spironolactone Spironolactone Spironolactone may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Amphotericin B Injection Amphotericin B Injection Amphotericin B may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Mercaptopurine Mercaptopurine The risk or severity of bleeding can be increased when Edoxaban is combined with Mercaptopurine.
Phytonadione Phytonadione Phylloquinone may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Amikacin Injection Amikacin Injection Amikacin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Nadolol Nadolol Nadolol may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Allopurinol Allopurinol Allopurinol may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Clomiphene Clomiphene The serum concentration of Edoxaban can be increased when it is combined with Clomifene.
Flavoxate Flavoxate Flavoxate may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Fluorouracil Injection Fluorouracil Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Fluorouracil.
Colchicine Colchicine The serum concentration of Edoxaban can be increased when it is combined with Colchicine.
Cefaclor Cefaclor Cefaclor may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Cefadroxil Cefadroxil Cefadroxil may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection Cefazolin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Cephalexin Cephalexin Cephalexin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Cefoxitin Injection Cefoxitin Injection Cefoxitin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Dacarbazine Dacarbazine Dacarbazine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Acetazolamide Acetazolamide Acetazolamide may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Cefotaxime Injection Cefotaxime Injection Cefotaxime may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Calcitonin Salmon Injection Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ketoconazole Ketoconazole The serum concentration of Edoxaban can be increased when it is combined with Ketoconazole.
Pyrantel Pyrantel Edoxaban may decrease the excretion rate of Pyrantel which could result in a higher serum level.
Thiotepa Injection Thiotepa Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Thiotepa.
Vincristine Injection Vincristine Injection The serum concentration of Vincristine can be increased when it is combined with Edoxaban.
Dipyridamole Dipyridamole The risk or severity of bleeding can be increased when Edoxaban is combined with Dipyridamole.
Vinblastine Vinblastine The serum concentration of Edoxaban can be increased when it is combined with Vinblastine.
Ethacrynic Acid Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Colistimethate Injection Colistimethate Injection Colistimethate may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Metoprolol Metoprolol Metoprolol may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Aspirin Aspirin The risk or severity of bleeding can be increased when Edoxaban is combined with Acetylsalicylic acid.
Salsalate Salsalate The risk or severity of bleeding and hemorrhage can be increased when Salsalate is combined with Edoxaban.
Chlorambucil Chlorambucil The risk or severity of bleeding can be increased when Edoxaban is combined with Chlorambucil.
Alprazolam Alprazolam Alprazolam may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Temazepam Temazepam Temazepam may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Triazolam Triazolam Triazolam may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Dicyclomine Dicyclomine Dicyclomine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Propantheline Propantheline Propantheline may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Trimethoprim Trimethoprim Trimethoprim may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Nifedipine Nifedipine Nifedipine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Timolol Timolol Timolol may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Verapamil Verapamil The serum concentration of Edoxaban can be increased when it is combined with Verapamil.
Pindolol Pindolol Pindolol may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Cisplatin Injection Cisplatin Injection Edoxaban may decrease the excretion rate of Cisplatin which could result in a higher serum level.
Diflunisal Diflunisal The risk or severity of bleeding and hemorrhage can be increased when Diflunisal is combined with Edoxaban.
Piroxicam Piroxicam The risk or severity of bleeding and hemorrhage can be increased when Piroxicam is combined with Edoxaban.
Bumetanide Bumetanide Bumetanide may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Streptozocin Streptozocin The risk or severity of bleeding can be increased when Edoxaban is combined with Streptozocin.
Etoposide Etoposide The serum concentration of Edoxaban can be increased when it is combined with Etoposide.
Glipizide Glipizide Glipizide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Indapamide Indapamide Indapamide may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Amoxicillin Amoxicillin Amoxicillin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Oxacillin Injection Oxacillin Injection Oxacillin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Pentoxifylline Pentoxifylline The therapeutic efficacy of Edoxaban can be increased when used in combination with Pentoxifylline.
Pentamidine Injection Pentamidine Injection Pentamidine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ceftriaxone Injection Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Labetalol Labetalol Labetalol may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Auranofin Auranofin Auranofin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection Leuprolide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Gemfibrozil Gemfibrozil Gemfibrozil may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ceftazidime Injection Ceftazidime Injection Ceftazidime may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ketoprofen Ketoprofen The risk or severity of bleeding and hemorrhage can be increased when Ketoprofen is combined with Edoxaban.
Cefotetan Injection Cefotetan Injection Cefotetan may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Flurbiprofen Flurbiprofen The risk or severity of bleeding and hemorrhage can be increased when Flurbiprofen is combined with Edoxaban.
Amiodarone Amiodarone The serum concentration of Edoxaban can be increased when it is combined with Amiodarone.
Aztreonam Injection Aztreonam Injection Aztreonam may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Buspirone Buspirone Buspirone may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ciprofloxacin Ciprofloxacin Ciprofloxacin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Mesalamine Mesalamine The risk or severity of bleeding and hemorrhage can be increased when Mesalazine is combined with Edoxaban.
Diclofenac Diclofenac The risk or severity of bleeding and hemorrhage can be increased when Diclofenac is combined with Edoxaban.
Fluoxetine Fluoxetine The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Edoxaban.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Interferon alfa-2b.
Cefixime Cefixime The therapeutic efficacy of Edoxaban can be decreased when used in combination with Cefixime.
Clozapine Clozapine Clozapine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Estazolam Estazolam Estazolam may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Idarubicin Idarubicin The risk or severity of bleeding can be increased when Edoxaban is combined with Idarubicin.
Didanosine Didanosine Didanosine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Fludarabine Injection Fludarabine Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Fludarabine.
Pentostatin Injection Pentostatin Injection Pentostatin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Clarithromycin Clarithromycin The serum concentration of Edoxaban can be increased when it is combined with Clarithromycin.
Etodolac Etodolac The risk or severity of bleeding and hemorrhage can be increased when Etodolac is combined with Edoxaban.
Fosinopril Fosinopril Fosinopril may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Nabumetone Nabumetone The risk or severity of bleeding and hemorrhage can be increased when Nabumetone is combined with Edoxaban.
Pravastatin Pravastatin The serum concentration of Edoxaban can be increased when it is combined with Pravastatin.
Simvastatin Simvastatin The serum concentration of Edoxaban can be increased when it is combined with Simvastatin.
Teniposide Injection Teniposide Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Teniposide.
Itraconazole Itraconazole The serum concentration of Edoxaban can be increased when it is combined with Itraconazole.
Lisinopril Lisinopril Lisinopril may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Oxaprozin Oxaprozin The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Edoxaban.
Bisoprolol Bisoprolol The serum concentration of Edoxaban can be increased when it is combined with Bisoprolol.
Isradipine Isradipine Isradipine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Venlafaxine Venlafaxine Venlafaxine may increase the antiplatelet activities of Edoxaban.
Fluvoxamine Fluvoxamine The risk or severity of hemorrhage can be increased when Fluvoxamine is combined with Edoxaban.
Nefazodone Nefazodone The risk or severity of hemorrhage can be increased when Nefazodone is combined with Edoxaban.
Lamotrigine Lamotrigine Lamotrigine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Valacyclovir Valacyclovir Valaciclovir may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Tramadol Tramadol Tramadol may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Vinorelbine Injection Vinorelbine Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Vinorelbine.
Carboplatin Injection Carboplatin Injection Carboplatin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ifosfamide Injection Ifosfamide Injection The risk or severity of bleeding can be increased when Ifosfamide is combined with Edoxaban.
Bupropion Bupropion Bupropion may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Ticlopidine Ticlopidine The risk or severity of bleeding can be increased when Ticlopidine is combined with Edoxaban.
Saquinavir Saquinavir The serum concentration of Edoxaban can be increased when it is combined with Saquinavir.
Metformin Metformin Metformin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Dalteparin Injection Dalteparin Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Dalteparin.
Nisoldipine Nisoldipine Nisoldipine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Lamivudine Lamivudine Lamivudine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Acarbose Acarbose Acarbose may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Gemcitabine Injection Gemcitabine Injection The serum concentration of Edoxaban can be increased when it is combined with Gemcitabine.
Ritonavir Ritonavir The serum concentration of Edoxaban can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The risk or severity of bleeding can be increased when Edoxaban is combined with Docetaxel.
Cidofovir Injection Cidofovir Injection Cidofovir may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Meropenem Injection Meropenem Injection Meropenem may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Clomipramine Clomipramine Clomipramine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Fosfomycin Fosfomycin Fosfomycin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Topiramate Topiramate Topiramate may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Pramipexole Pramipexole Pramipexole may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Fexofenadine Fexofenadine The serum concentration of Edoxaban can be increased when it is combined with Fexofenadine.
Azithromycin Azithromycin The risk or severity of adverse effects can be increased when Azithromycin is combined with Edoxaban.
Carvedilol Carvedilol The serum concentration of Edoxaban can be increased when it is combined with Carvedilol.
Nilutamide Nilutamide Nilutamide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Flutamide Flutamide Flutamide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Selegiline Selegiline The risk or severity of bleeding and hemorrhage can be increased when Selegiline is combined with Edoxaban.
Sertraline Sertraline The risk or severity of bleeding can be increased when Sertraline is combined with Edoxaban.
Propafenone Propafenone The serum concentration of Edoxaban can be increased when it is combined with Propafenone.
Tamsulosin Tamsulosin Tamsulosin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Quetiapine Quetiapine Quetiapine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Cefepime Injection Cefepime Injection Cefepime may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Cefprozil Cefprozil Cefprozil may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Cefpodoxime Cefpodoxime Cefpodoxime may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Cetirizine Cetirizine Cetirizine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Paroxetine Paroxetine The risk or severity of hemorrhage can be increased when Paroxetine is combined with Edoxaban.
Tolcapone Tolcapone Tolcapone may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Citalopram Citalopram The risk or severity of hemorrhage can be increased when Citalopram is combined with Edoxaban.
Capecitabine Capecitabine Capecitabine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Abacavir Abacavir Abacavir may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Sildenafil Sildenafil The serum concentration of Edoxaban can be increased when it is combined with Sildenafil.
Celecoxib Celecoxib The risk or severity of bleeding and hemorrhage can be increased when Celecoxib is combined with Edoxaban.
Rosiglitazone Rosiglitazone Rosiglitazone may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Tolterodine Tolterodine Tolterodine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Thalidomide Thalidomide The risk or severity of bleeding can be increased when Edoxaban is combined with Thalidomide.
Oseltamivir Oseltamivir Oseltamivir may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Balsalazide Balsalazide The risk or severity of bleeding and hemorrhage can be increased when Balsalazide is combined with Edoxaban.
Nateglinide Nateglinide Nateglinide may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Rabeprazole Rabeprazole Rabeprazole may decrease the excretion rate of Edoxaban which could result in a higher serum level.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists

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