No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Witch Hazel Ingredients & Drug Interactions

by Herb Pharm

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Witch Hazel is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for skin irritation and inflammation, hemorrhoids, minor cuts and bruises.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Witch Hazel by Herb Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: witch hazel leaf and young twig extract. Witch hazel is a plant extract traditionally used for skin concerns, especially hemorrhoids.

The inactive ingredients are certified organic cane alcohol, distilled water, and certified organic vegetable glycerin — these are excipients that preserve and deliver the extract.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: skin health and minor wound care.
  • We looked for evidence on: Acne, Atopic dermatitis (eczema), Bruises, Burns, Hemorrhoids, Insect bite — and 4 related terms.
  • The strongest evidence on file: Witch Hazel is rated "Possibly Effective" for Hemorrhoids (Natural Medicines).
  • Also on file: Witch Hazel is rated "Possibly Ineffective" for Atopic dermatitis (eczema).
  • Also on file: Witch Hazel is rated "Insufficient Reliable Evidence To Rate" for Acne, Burns, Minor bleeding, Skin irritation, and more.

The evidence supports witch hazel's use for hemorrhoids, where it's rated possibly effective. For varicose veins and postmenopausal conditions, the evidence isn't yet established well enough to rate.

For eczema (atopic dermatitis), the data suggests it's possibly ineffective.

The evidence, ingredient by ingredient Witch Hazel

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Topically, witch hazel is generally well tolerated short-term; a small number of people develop contact dermatitis, redness, or burning. This product is meant for topical use only — not to be taken by mouth.

Safety data are limited, so check with your doctor before using it, especially if you're pregnant, breastfeeding, or have a medical condition. Witch hazel contains tannins, and some evidence links regular consumption of high-tannin herbs with increased risk of certain cancers, though other evidence suggests tannins may prevent cancer — the picture is mixed.

Oral use at high doses may carry risks to the kidneys and liver.

Side effects, ingredient by ingredient Witch Hazel

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the witch hazel extract we checked. If you take any medications, you're welcome to run them through our search tool or ask us directly.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Witch hazel is a reasonable choice if you're looking for topical relief from hemorrhoids and don't have a documented sensitivity to it. Use it on skin only, not by mouth.

If you're pregnant, breastfeeding, or have liver or kidney concerns, talk to your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Witch Hazel, straight from the product label.

Brand Herb Pharm
Barcode (UPC) 090700002473
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 220385
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Witch Hazel by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
0.7 mL
Servings per container
168
UPC/BARCODE
090700002473
IngredientAmount% DV
Witch Hazel leaf & young twig (Hamamelis virginiana) extract685 mg--

Other ingredients: certified organic Cane Alcohol, distilled Water, certified organic Vegetable Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use Shake well before using Add 1 full squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 4 times per day. Best taken between meals.

Precautions

Keep out of the reach of children

Storage

Store away from heat & light

Formula

Hamamelis virginiana

Witch Hazel liquid extract

We prepare our Witch Hazel extract from the leaf & young twig of responsibly wildcrafted Hamamelis virginiana shrubs.

Formulation

Optimal well-being

Dry herb/menstruum ratio: 1:5

FDA Statement of Identity

Herbal Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Witch Hazel by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Witch Hazel by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container168 Amounts shown are per serving.

685 mg per serving

Witch hazel is a plant-based astringent used mostly on the skin for minor irritation, hemorrhoids, and oily skin. It is generally well tolerated as a...

Witch Hazel leaf & young twig (Hamamelis virginiana) extract monograph & interactions

Other (inactive) ingredients: Certified organic Cane Alcohol, Distilled Water, Certified organic Vegetable Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Witch Hazel by Herb Pharm Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Witch Hazel. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Witch Hazel, from the product label.

Herb Pharm

See all Herb Pharm products
Name
Herb Pharm
City
Williams
State
OR
ZipCode
97544
Phone Number
800-348-4372
Web Address
www.herb-pharm.com
Pharmacist Counseling Corner

Witch Hazel by Herb Pharm: Common Questions

Does Witch Hazel by Herb Pharm interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Witch Hazel. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Witch Hazel contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this if I'm pregnant or breastfeeding?
The safety data on file don't include a pregnancy or breastfeeding rating for witch hazel. Because the data are limited, there isn't enough information to know either way. Talk with your doctor or pharmacist to decide what's right for you.
What's witch hazel actually used for?
Witch hazel is possibly effective for hemorrhoids. It's not effective for eczema, and there isn't enough reliable evidence yet to say whether it helps varicose veins or postmenopausal symptoms.
Can I swallow this product?
No — this product is for topical use only, on your skin. It's not meant to be taken by mouth.
Is contact dermatitis common with witch hazel?
It's not common, but a small number of people do develop redness, burning, or contact dermatitis when they apply it to their skin. Stop use if that happens and talk to us.
Does witch hazel have any serious side effects?
Topically, witch hazel is generally well tolerated. If someone were to take it by mouth in high doses, the tannins in it could theoretically damage the kidneys or liver, but this product is for skin use only, so that risk doesn't apply here.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Witch Hazel is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Witch Hazel label
Go deeper

The Full Monographs Behind Witch Hazel’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Witch Hazel's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Witch Hazel 7 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  4. Hormann HP, Korting HC. Evidence for the efficacy and safety of topical herbal drugs in dermatology: part I: anti-inflammatory agents. Phytomedicine 1994;1:161-71. PubMed
  5. Wolff, H. H. and Kieser, M. Hamamelis in children with skin disorders and skin injuries: results of an observational study. Eur.J.Pediatr. 2007;166(9):943-948. PubMed
  6. Khanna, N. and Datta, Gupta S. Rejuvenating facial massage--a bane or boon? Int J Dermatol. 2002;41(7):407-410. PubMed
  7. Theisen LL, Erdelmeier CA, Spoden GA, Boukhallouk F, Sausy A, Florin L, Muller CP. Tannins from Hamamelis virginiana bark extract: characterization and improvement of the antiviral efficacy against influenza A virus and human papillomavirus. PLoS One. 201 PubMed

See these in context on the Witch Hazel monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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