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Dietary supplement

Wormwood Chocolate Flavor Ingredients & Drug Interactions

by TerraVita

Wormwood Chocolate Flavor label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Wormwood Chocolate Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Wormwood Chocolate Flavor is a dietary supplement by TerraVita with 1 active ingredient. Its ingredients are commonly taken for malaria (traditional), fever, inflammation.Based on those ingredients, 892 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Wormwood Glycerite Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Wormwood Chocolate Flavor by TerraVita

Ask about any prescription or over-the-counter medication and we check it for interactions with Wormwood Chocolate Flavor by TerraVita — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Wormwood Chocolate Flavor by TerraVita

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: wormwood glycerite liquid extract (also called Sweet Annie). Wormwood is a traditional herb that's been studied for hay fever and a few other conditions.

The preparation also includes glycerin and chocolate flavor as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Sweet Annie's overall clinical evidence instead.

Moderate

Some clinical evidence supports Sweet Annie for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Allergic rhinitis (hay fever) — rated "Possibly Effective" (Natural Medicines).

Wormwood shows possibly effective evidence for allergic rhinitis (hay fever) based on the data we hold. For other conditions — nonalcoholic fatty liver disease, malaria, and osteoarthritis — the evidence isn't established enough to rate.

The ingredient is generally used short-term, and quality and dose vary widely, so it should never replace proven treatments.

The evidence, ingredient by ingredient Sweet Annie

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Wormwood is generally well tolerated when taken by mouth, though nausea and vomiting are the most common side effects. Rarely, it can cause hepatotoxicity (liver damage) — one reported case involved liver inflammation after taking a related compound for 10 days.

A mild allergic reaction (rash and cough) has been reported once, and some people have experienced numbness of the tongue or throat itching when taking low doses under the tongue. The safety data advises against use during pregnancy because of possible harm to the developing baby, and there isn't enough information to know whether it's safe while breastfeeding — talk with your doctor or pharmacist for personalized advice if either applies to you.

Side effects, ingredient by ingredient Sweet Annie

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sweet Annie.
  • The most serious interaction on file is rated Moderate.
  • For scale: 893 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check with your doctor or pharmacist if you're on hepatotoxic drugs (anything that stresses the liver), drugs metabolized by the CYP3A4 enzyme system, or drugs metabolized by the CYP2B6 enzyme system — all carry a Moderate interaction risk. The combination of wormwood with liver-stressing medications is particularly important to clarify beforehand.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you're dealing with hay fever and want to explore wormwood, it's worth discussing with your doctor or pharmacist — especially because you'll need to check it against any medications you're on. The biggest caution is liver risk, both from the herb itself and from how it might interact with drugs your liver processes.

Don't use it during pregnancy, and get personalized guidance on breastfeeding before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wormwood Chocolate Flavor, straight from the product label.

Brand TerraVita
Barcode (UPC) 064434282043
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Nov 22, 2022
DSLD ID 280647
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wormwood Chocolate Flavor by TerraVita, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
25 Drop(s)
Maximum serving Sizes:
40 Drop(s)
Servings per container
227
UPC/BARCODE
064434282043
IngredientAmount% DV
Wormwood Glycerite Liquid Extract0.13 mL--

Other ingredients: Glycerin, Chocolate flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Copyright 2005 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Formula

Glycerite liquid extract (1:5) Chocolate flavored

Formulation

Alcohol free

Suggested/Recommended/Usage/Directions

Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.

Precautions

Keep away from children.

Do not use if safety seal around cap is broken or missing.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Wormwood Chocolate Flavor by TerraVita label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Wormwood Chocolate Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Wormwood Chocolate Flavor by TerraVita

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.

Wormwood Glycerite Liquid Extract

Interacts with
892 drugs
0.13 mL per serving

Sweet Annie (Artemisia annua) is the source of artemisinin, a compound used in prescription antimalarial drugs. While the purified drug is well studie...

Wormwood Glycerite Liquid Extract monograph & interactions

Other (inactive) ingredients: Glycerin, Chocolate flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Wormwood Chocolate Flavor by TerraVita Drug Interactions

Want to check YOUR meds against Wormwood Chocolate Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
892Drugs
892 Moderate

Ingredients driving the most interactions

Wormwood Glycerite Liquid Extract 892

Individual Drug Interactions

The ingredients in Wormwood Chocolate Flavor interact with 892 drugs. Click any drug to see the details.

1 of the 1 ingredient in Wormwood Chocolate Flavor interact with drugs. Each result below shows which ingredient is responsible. Wormwood Glycerite Liquid Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Wormwood Chocolate Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wormwood Glycerite Liquid Extract3 drug types · 892 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP2B6.
In vitro research shows that the Sweet Annie constituent artemisinin induces CYP2B6, possibly increasing CYP2B6 activity by 1.6-fold. However, Sweet Annie extract seems to inhibit the activity of CYP2B6 in vitro, suggesting that other constituents of Sweet Annie play a role in its effects on the overall activity of this enzyme. More information is needed to determine whether taking Sweet Annie extract affects the metabolism of CYP2B6 substrates.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that the Sweet Annie constituent artemisinin induces CYP3A4, possibly increasing CYP3A4 activity by 1.9-fold. However, Sweet Annie extract seems to inhibit the activity of CYP3A4 in vitro, suggesting that other constituents of Sweet Annie play a role in its effects on the overall activity of this enzyme. More information is needed to determine whether taking Sweet Annie extract affects the metabolism of CYP3A4 substrates.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, concomitant use might have additive adverse hepatotoxic effects.
There is some concern that Sweet Annie can adversely affect the liver.

Likelihood Possible Evidence D
Wormwood Glycerite Liquid Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Wormwood Chocolate Flavor, from the product label.

TerraVita

See all TerraVita products
Name
ZooScape LLC
Phone Number
844-449-0444
Web Address
www.ZooScape.com
Pharmacist Counseling Corner

Wormwood Chocolate Flavor by TerraVita: Common Questions

Does Wormwood Chocolate Flavor by TerraVita interact with any medications?
Yes. Based on its ingredients, Wormwood Chocolate Flavor has a known interaction with 892 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wormwood Chocolate Flavor contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
No — the safety data advises against use during pregnancy because of possible harm to the developing baby. Talk with your doctor or pharmacist about safer alternatives for hay fever or any other reason you're considering this product.
Is it safe to breastfeed while taking wormwood?
There isn't enough safety information to know either way. Talk with your doctor or pharmacist before starting this product if you're breastfeeding — they can help you weigh the unknowns and suggest other options if needed.
What are the most common side effects?
Nausea and vomiting are the most common side effects when taken by mouth. Rarely, it can cause liver damage, and a few people have reported mild allergic reactions like rash or cough, or numbness of the tongue if taken sublingually.
Does this actually work for hay fever?
Wormwood has possibly effective evidence for allergic rhinitis (hay fever) in the data we hold, which means there's some research support but it's not definitive. Remember, it should never replace proven hay fever treatments.
Can I use this long-term?
It's generally used short-term, and quality and dose vary widely between products. Because of the liver concerns and the way it can interact with medications, talk with your doctor or pharmacist about how long is safe for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Wormwood Chocolate Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wormwood Chocolate Flavor label
Go deeper

The Full Monographs Behind Wormwood Chocolate Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sweet Annie

Interacts with 892 drugs

Sweet Annie (Artemisia annua) is the source of artemisinin, a compound used in prescription antimalarial drugs. While the purified drug is well studied for malaria, the herb itself as a supp...

Read the full Sweet Annie monograph →
Sources

Sources & How We Checked

Wormwood Chocolate Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sweet Annie 11 references
  1. Mueller MS, Karhagomba IB, Hirt HM, Wemakor E. The potential of Artemisia annua L. as a locally produced remedy for malaria in the tropics: agricultural, chemical and clinical aspects. J Ethnopharmacol 2000;73:487-93. PubMed
  2. Rath K, Taxis K, Walz G, et al. Pharmacokinetic study of artemisinin after oral intake of a traditional preparation of Artemisia annua L. (annual wormwood). Am J Trop Med Hyg 2004;70:128-32. DOI
  3. Centers for Disease Control and Prevention (CDC). Hepatitis temporally associated with an herbal supplement containing artemisinin-Washington, 2008. MMWR Morb Mortal Wkly Rep 2009;58:854-8.
  4. Xing J, Kirby BJ, Whittington D, et al. Evaluation of P450 inhibition and induction by artemisinin antimalarials in human liver microsomes and primary human hepatocytes. Drug Metabl Dispos 2012;40(9):1757-64. PubMed
  5. Savage RL, Hill GR, Barnes J, Kenyon SH, Tatley MV. Suspected hepatotoxicity with a supercritical carbon dioxide extract of Artemisia annua in grapeseed oil used in New Zealand. Front Pharmacol. 2019;10:1448. PubMed
  6. Ruperti-Repilado FJ, Haefliger S, Rehm S, et al. Danger of herbal tea: a case of acute cholestatic hepatitis due to Artemisia annua tea. Front Med (Lausanne). 2019;6:221. PubMed
  7. Yang J, Shen Z, Liu L, et al. Clinical efficacy and safety of Artesimia annua-Sublingual immunotherapy in seasonal allergic rhinitis patients based on different intervention time. Int Arch Allergy Immunol 2022;183(8):852-859.
  8. Kane NF, Kiani BH, Desrosiers MR, Towler MJ, Weathers PJ. Artemisia extracts differ from artemisinin effects on human hepatic CYP450s 2B6 and 3A4 in vitro. J Ethnopharmacol 2022. DOI
  9. Feng Y, Cao Y, Liu Y, et al. Clinical efficacy and safety of coseasonal initiation of Artemisia annua sublingual immunotherapy on patients with Artemisia-induced rhinoconjunctivitis. Am J Otolaryngol 2023;44(5):103942. PubMed
  10. Yang J, Wang W, Shen Z, et al. Efficacy and safety of Artemisia annua sublingual immunotherapy in patients with seasonal allergic rhinoconjunctivitis over two pollen seasons. Eur Arch Otorhinolaryngol. 2023;280(11):4939-4947. PubMed
  11. Shen Z, Zhang P, Kang W, et al. Clinical efficacy in one-year treatment with Artemisia annua-SLIT drops in monosensitized and polysensitized individuals. Am J Otolaryngol 2023;44(6):104002. PubMed

See these in context on the Sweet Annie monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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