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Calcium Chloride / Potassium Chloride / Sodium Chloride

Calcium chloride, potassium chloride and sodium chloride are salts (electrolytes) found in Ringer's-type solutions, which are given by IV to replace fluid and electrolytes, or used as a sterile rinse in irrigation products.

Brand names Lactated RingersLactated Ringers Irrigation
Drug classes Acidifying Activity
Rx Forms 3
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026 Content updated Oct 8, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 19 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

✓No current FDA shortage listed · checked Oct 8, 2026
Calcium Chloride / Potassium Chloride / Sodium Chloride at a glance The quick version — the full detail is in the Patient Information Guide below.
Dr. Brian Staiger, PharmD, BCPS
The Pharmacist’s Take By · Clinical pharmacist · Written

These salts make up Lactated Ringer’s and Ringer’s solutions, among the most common hospital IV fluids for replacing lost water and electrolytes, on the market since about 1971 and available generically, with a sterile irrigation version for rinsing during procedures. Given only by your care team through a vein, these fluids are very well tolerated, and most people notice little beyond soreness or swelling at the IV site. The serious watch-out is the antibiotic ceftriaxone, which can bind the calcium into deadly particles in a newborn’s lungs and kidneys, so the two are never combined in babies 28 days or younger. Kidney disease, heart disease and electrolyte problems call for extra caution.

Clinical pearls

  • If you take digoxin, mention it, because the calcium can boost digoxin’s effect and trigger serious heart rhythm problems.
  • Lithium users should speak up, since these fluids can lower lithium levels and may mean extra blood checks.
  • Tell the team about any ACE inhibitor, angiotensin receptor blocker or potassium-sparing water pill, since potassium can climb dangerously.
  • The liver turns the lactate in Lactated Ringer’s into bicarbonate, so tell your team about severe liver disease.
How we write & review this content — our editorial policy →
How you get itPrescription only
Comes asInjection, Other oral form, Oral solution
Earliest FDA record1971
Companies listing it with the FDA8
FDA label last updatedNov 5, 2025
FDA’s strongest warning (boxed)None on the label

Patient information guide A plain-language walkthrough of Calcium Chloride / Potassium Chloride / Sodium Chloride, written from its FDA label.

What Calcium Chloride / Potassium Chloride / Sodium Chloride is used for

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These calcium, potassium and sodium chloride solutions are used in different ways depending on the product.

  • Lactated Ringer's Injection and Lacellate Solution (IV): a source of water and electrolytes, or an alkalinizing agent.
  • Lactated Ringer's and Dextrose and Ringer's (IV): replace extracellular fluid and electrolyte losses, with or without minimal carbohydrate calories.
  • Lactated Ringer's Irrigation: general irrigation, washing and rinsing with a sterile electrolyte solution.

How Calcium Chloride / Potassium Chloride / Sodium Chloride works

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The solutions contain sodium, potassium, calcium and chloride in amounts that resemble normal blood plasma. Sodium controls water balance. Potassium supports nerves and muscles, including the heart. Calcium supports clotting and normal heart function.

Lactated Ringer's also contains sodium lactate. The liver turns lactate into bicarbonate, which helps counter excess acid. Dextrose versions add calories.

Calcium Chloride / Potassium Chloride / Sodium Chloride dosage

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The IV products are given only by a healthcare professional. Dose, rate and duration depend on your age, weight, condition, lab results and other treatments.

  • Lacellate Solution: use the container's contents right after opening, and do not reconnect partly used containers.
  • Additives must be checked for compatibility and mixed using sterile technique.
  • Lactated Ringer's Irrigation: the amount depends on the area being rinsed and the procedure.

Dosing details from the FDA-approved label

From the Calcium Chloride / Potassium Chloride / Sodium Chloride prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.

  • Lactated Ringer's Injection (intravenous use)
    • The recommended dosage and duration is directed by a physician based on the patient's age, weight, clinical condition, and concomitant therapy
    • Monitor changes in electrolyte concentrations especially during prolonged use.
  • Lactated Ringer's Injection with ceftriaxone
    • Do not administer simultaneously with ceftriaxone via a Y-site in neonates (28 days of age or younger)
    • In patients older than 28 days, ceftriaxone and Lactated Ringer's Injection may be administered sequentially if the infusion lines are thoroughly flushed between infusions with a compatible fluid
    • Neonates 28 days of age or younger
  • Lacellate Solution / Lactated Ringer's Injection, USP (VIAFLEX containers)
    • As directed by a physician
    • Dosage, rate and duration of administration are to be individualized and dependent upon the indication for use, the patient's age, weight, concomitant treatment and clinical condition as well as laboratory determinations
  • Lactated Ringer's / Lactated Ringer's and Dextrose Injection; Ringer's Injection
    • The dose is dependent upon the age, weight and clinical condition of the patient
    • Dosage and constant infusion rate of intravenous dextrose must be selected with caution in pediatric patients, particularly neonates and low birth weight infants, because of the increased risk of hyperglycemia/hypoglycemia.
  • Lactated Ringer's Irrigation
    • The dose is dependent upon the capacity or surface area of the structure to be irrigated and the nature of the procedure
    • When used as a vehicle for other drugs, follow the manufacturer's recommendations.
Read the label’s full dosing text

2 DOSAGE AND ADMINISTRATION The recommended dosage and duration is based on the patient’s age, weight, clinical condition, and concomitant therapy. ( 2.1 ) To reduce the risk of air embolism, adhere to the preparation instructions. ( 2.2 , 5.2 ) Lactated Ringer’s Injection is for intravenous use ( 2.3 ) Instructions for Intravenous Administration of EXCEL ® Plus Container ( 2.4 ) Do not administer Lactated Ringer’s Injection simultaneously with ceftriaxone in neonates (28 days of age or younger) due to serious risks. ( 2.5 ) See full prescribing information for information dosage considerations, preparation, administration, and drug incompatibilities. ( 2 ) 2.1 Dosage Considerations The recommended dosage and duration of Lactated Ringer’s Injection is directed by a physician based on the patient’s age, weight, clinical condition, and concomitant therapy. Evaluate the patient’s clinical status and monitor changes in electrolyte concentrations especially during prolonged use of Lactated Ringer’s Injection to optimize clinical status. 2.2 Important Preparation Instructions Visually inspect the Lactated Ringer’s Injection solution for particulate matter and discoloration. Do not administer Lactated Ringer’s Injection unless the solution is clear and the container and seals are intact. If additives are determined to be compatible with Lactated Ringer’s Injection then using aseptic technique, mix thoroughly; do not store solutions containing additives. After mixing, do not use if there is discoloration or formation of precipitates. To reduce the risk of air embolism, adhere to the following Lactated Ringer’s Injection preparation instructions [see Warnings and Precautions (5.2) ] : Use a non-vented infusion set or close the vent on a vented set. Use a dedicated line without any connections (do not connect flexible containers in series). The use of pressure infusion is not recommended as a method to increase flow rates. However, if pressure infusion is required, ensure that any air within the bag is fully evacuated prior to initiation of infusion. If using a pumping device to administer Lactated Ringer’s Injection , turn off the pump before the container is empty. Preparation Instructions for EXCEL ® Plus Container 1. Tear overwrap down at notch and remove solution container. 2. Check for minute leaks by squeezing solution container firmly.

Excerpted — the section continues on the label. Read the full Dosage and Administration section on DailyMed →

Calcium Chloride / Potassium Chloride / Sodium Chloride side effects

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Most reactions come from the solution, the IV technique, or too much or too little of an electrolyte.

Common side effects

  • Fever
  • Infection or irritation at the injection site
  • Vein inflammation or clots near the injection site
  • Fluid leaking out of the vein
  • Too much fluid in the body
  • Nausea, vomiting, abdominal pain or diarrhea (potassium-containing solutions)
  • Hives or itching

When to get medical help

  • Tell your care team right away about hives, swelling of the face, eyes or throat, sneezing, coughing or trouble breathing. These can be allergic reactions, and the infusion must be stopped.
  • Report confusion, weakness, tingling in the hands or feet, slow or irregular heartbeat or trouble breathing. These can signal too much potassium.
  • Report headache, nausea, vomiting, seizures or extreme sleepiness. These can signal low sodium.
  • Report swelling, shortness of breath or a feeling of fluid overload.
  • Report muscle cramps or convulsions, or confusion, drowsiness or hallucinations. These can signal calcium that is too low or too high.
  • Newborns given ceftriaxone with calcium-containing IV fluids have died.

Calcium Chloride / Potassium Chloride / Sodium Chloride warnings and precautions

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  • Ceftriaxone can cause fatal calcium precipitates in newborns. It must not be used together with these solutions in newborns.
  • Air embolism has been reported with pressurized IV fluids.
  • Allergic reactions, including anaphylaxis and angioedema (deep swelling), can occur. Stop the infusion if signs appear.
  • Potassium, sodium and calcium imbalances, fluid overload and acid-base problems are possible.
  • It is not for severe potassium deficiency, lactic acidosis or severe metabolic acidosis.

Calcium Chloride / Potassium Chloride / Sodium Chloride interactions

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Several medicines change how these solutions affect your body.

  • Ceftriaxone: dangerous calcium precipitate.
  • Digoxin: calcium can raise the risk of digoxin toxicity.
  • Lithium: levels may fall.
  • Potassium-raising drugs: risk of high potassium.
  • Thiazide diuretics and vitamin D: risk of high calcium.
  • Diuretics and certain seizure, psychiatric or cancer drugs: risk of low sodium.
  • Corticosteroids: sodium and fluid retention.
  • Drugs cleared by the kidney depending on urine pH: clearance may change.

Interactions listed in the FDA-approved label

From the Calcium Chloride / Potassium Chloride / Sodium Chloride prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.

  • Drugs that affect electrolyte and/or fluid balance: Concomitant use may affect electrolyte concentrations and fluid balance. Avoid concomitant use. If it cannot be avoided, closely monitor electrolyte concentrations and fluid balance.
  • Drugs associated with hyperkalemia (potassium-sparing diuretics, ACE inhibitors, angiotensin II receptor antagonists, calcineurin inhibitors): Increases the risk of severe and potentially fatal hyperkalemia. Avoid use. If it cannot be avoided, closely monitor serum potassium concentrations.
  • Drugs associated with hyponatremia (diuretics, drugs that cause SIADH such as arginine vasopressin analogs, certain antiepileptic, psychotropic, or cytotoxic drugs): May increase the risk of developing hyponatremia. Avoid use. If it cannot be avoided, closely monitor serum sodium concentrations.
  • Thiazide diuretics or vitamin D: These drugs can increase the risk of hypercalcemia. Avoid use. If it cannot be avoided, closely monitor serum calcium concentrations.
  • Drugs associated with sodium and fluid retention (corticosteroids, corticotropin): May increase the risk of hypernatremia and volume overload. Avoid use. If it cannot be avoided, closely monitor serum electrolytes, fluid balance, and acid-base balance.
  • Lithium: Renal sodium and lithium clearance may be increased, which may result in decreased lithium concentrations. Avoid use. If it cannot be avoided, increase the frequency of monitoring of serum lithium concentrations.
  • Digoxin: Calcium may increase digoxin's effects and lead to digoxin toxicity including serious or fatal cardiac arrhythmias. In digoxin-treated patients, consider reducing the volume and/or rate of Lactated Ringer's Injection administration.
  • Drugs with pH-dependent renal elimination: Due to the alkalinizing action of lactate, renal clearance of alkaline drugs may be decreased and renal clearance of acidic drugs may be increased.
  • Serum lactate interpretation in severe metabolic acidosis or severe hepatic impairment: Administration may interfere with the interpretation of serum lactate levels. Do not rely solely on serum lactate measurement to assess the patient's clinical status.
  • Ceftriaxone and citrate anticoagulated/preserved blood: Simultaneous administration risks serious harm in neonates (ceftriaxone) and coagulation from the calcium content (citrate blood through the same set). Do not give ceftriaxone simultaneously via Y-site in neonates; do not give citrate anticoagulated/preserved blood through the same administration set.
Read the label’s full interactions text

7 DRUG INTERACTIONS Drugs that Affect Electrolyte and/or Fluid Balance : Avoid concomitant use. If concomitant use cannot be avoided, closely monitor electrolyte concentrations and fluid balance. ( 7.1 ) Lithium : Avoid concomitant use. If concomitant use is unavoidable monitor serum lithium concentrations more frequently. ( 7.2 ) Digoxin : Consider reducing the volume or rate of Lactated Ringer’s Injection due to the increased risk of digoxin toxicity with calcium-containing solutions. ( 7.3 ) Drugs with pH-Dependent Renal Elimination : Renal clearance of acidic drugs may be increased. In contrast, renal clearance of alkaline drugs may be decreased. ( 7.4 ) 7.1 Drugs that Affect Electrolyte and/or Fluid Balance Hyperkalemia Administration of Lactated Ringer’s Injection to patients concomitantly treated or recently treated with drugs that are associated with hyperkalemia increases the risk of severe and potentially fatal hyperkalemia, especially in the presence of other hyperkalemia risk factors . Avoid use of Lactated Ringer’s Injection in patients receiving drugs that are associated with hyperkalemia (e.g., potassium-sparing diuretics, ACE inhibitors, angiotensin II receptor antagonists, or calcineurin inhibitors). If concomitant use cannot be avoided, closely monitor serum potassium concentrations during concomitant use [see Warnings and Precautions (5.4) ]. Hyponatremia Administration of Lactated Ringer’s Injection to patients treated concomitantly with drugs associated with hyponatremia may increase the risk of developing hyponatremia. These drugs include diuretics and those that cause SIADH (e.g., arginine vasopressin analogs, certain antiepileptic, psychotropic, or cytotoxic drugs). Avoid use of Lactated Ringer’s Injection in patients receiving such drugs. If use cannot be avoided, closely monitor serum sodium concentrations during concomitant use [see Warnings and Precautions (5.5) ] .

Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →

Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.

Check Calcium Chloride / Potassium Chloride / Sodium Chloride against a supplement or herb →

Before taking Calcium Chloride / Potassium Chloride / Sodium Chloride

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  • Do not use if allergic to sodium lactate.
  • Use is generally avoided in severe kidney disease and severe liver disease.
  • Extra caution with high potassium, high calcium, calcium kidney stones, heart disease and low sodium.
  • Pregnancy: used for decades during labor and delivery. Allergic reactions are reported more often in pregnancy.
  • Breastfeeding: not expected to harm a breastfed infant.
  • Children: monitor electrolytes closely in young children with immature kidneys.
  • Older adults: more likely to have electrolyte imbalance and reduced kidney function.

Calcium Chloride / Potassium Chloride / Sodium Chloride overdose

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Too much fluid or salt can cause fluid overload. Too much potassium can cause tingling, weakness, confusion, and dangerous heart rhythm changes. The infusion is stopped right away and corrective treatment is given, which may include IV dextrose with insulin, potassium-removing resins or dialysis.

How your body processes Calcium Chloride / Potassium Chloride / Sodium Chloride

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Most potassium (80 to 90%) leaves in the urine, with the rest in stool and sweat. The kidneys control sodium and chloride balance. The liver breaks lactate down to carbon dioxide and water.

How to store Calcium Chloride / Potassium Chloride / Sodium Chloride

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Avoid excessive heat. Protect from freezing. stored at room temperature (25°C); however, brief exposure up to 40°C does not adversely affect the product.

Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

Calcium Chloride / Potassium Chloride / Sodium Chloride: pharmacist answers to common questions

Quick, plain-English answers to the questions patients ask most about Calcium Chloride / Potassium Chloride / Sodium Chloride — the kind of thing our pharmacy team would talk through with you at the counter.

What is this solution used for?

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The IV versions replace water and electrolytes your body has lost, and Lactated Ringer's and Lacellate can also help counter excess acid. A separate Lactated Ringer's Irrigation product is used as a sterile rinse during procedures. It is not given by IV.

Can I take this at home?

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These are given by healthcare professionals. The IV product runs through a vein under supervision, and the irrigation product is used on a body area during a procedure. Your care team sets the amount and how long it runs.

Is it safe for people with kidney or heart problems?

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It takes extra care. Severe kidney disease can lead to high potassium and fluid overload, so the IV solution is usually avoided. Heart disease and high potassium also call for caution, and your team will watch your blood levels.

Are there medicines I shouldn't get with it?

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Yes. Ceftriaxone is the biggest concern, especially in newborns. Digoxin, lithium, thiazide diuretics, vitamin D, corticosteroids and drugs that raise potassium or lower sodium can also cause problems. Tell your team everything you take.

What side effects should I tell the nurse about?

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Speak up about pain, redness or swelling where the IV goes in, or fever. Tell them right away about hives, facial swelling, trouble breathing, confusion, weakness, an irregular heartbeat or swelling. The infusion can be stopped if needed.

Is it okay during pregnancy or breastfeeding?

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Lactated Ringer's has been used for decades during labor and delivery and is not expected to cause major problems. It is not expected to harm a breastfed infant. Allergic reactions are reported a bit more often in pregnancy.

Is Calcium Chloride / Potassium Chloride / Sodium Chloride available over the counter?

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No. Calcium Chloride / Potassium Chloride / Sodium Chloride is a prescription medicine: every Calcium Chloride / Potassium Chloride / Sodium Chloride product listed with the FDA is prescription only, so it is not sold over the counter. Your prescriber decides whether it is appropriate for you, and your pharmacist dispenses it.

When was Calcium Chloride / Potassium Chloride / Sodium Chloride first available?

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The earliest FDA record we hold for Calcium Chloride / Potassium Chloride / Sodium Chloride is from 1971: its first approval in Drugs@FDA or its earliest product listing in the NDC Directory, whichever is older. Many older medicines were in use before their first formal FDA approval, so this is the earliest date on record, not necessarily when Calcium Chloride / Potassium Chloride / Sodium Chloride was first used.

Who makes Calcium Chloride / Potassium Chloride / Sodium Chloride?

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8 companies currently list Calcium Chloride / Potassium Chloride / Sodium Chloride products in the FDA's NDC Directory, including B. Braun Medical Inc., Fresenius Kabi USA, LLC, Asclemed USA, Inc.. That count includes repackagers and distributors as well as manufacturers (companies that sell only the raw ingredient are not counted), so fewer companies actually make it; the label on your bottle names the one that supplied yours.

Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

More about Calcium Chloride / Potassium Chloride / Sodium Chloride on HelloPharmacist

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Detailed data & references for Calcium Chloride / Potassium Chloride / Sodium Chloride Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here. Each section below opens on a tap.

Calcium Chloride / Potassium Chloride / Sodium Chloride forms and strengths (how it comes)

Calcium Chloride / Potassium Chloride / Sodium Chloride is available in 3 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Need a version that does not list lactose, a gluten source, a dye or gelatin? Inactive ingredients differ by manufacturer: see Calcium Chloride / Potassium Chloride / Sodium Chloride inactive ingredients by manufacturer.

Injection

Into a vein
Brands Lactated Ringers
How this form is used
What it may be used for
  • Lactated Ringer's Injection is used as a source of water and electrolytes or as an alkalinizing agent in adults and children.
  • Lacellate Solution is used as a source of water and electrolytes or as an alkalinizing agent.
  • Lactated Ringer's and Dextrose and Ringer's are used to replace extracellular fluid and electrolyte losses, with or without minimal carbohydrate calories.
Important instructions
  • Lactated Ringer's Injection is for intravenous use only, and the dose and duration are set by a physician.
  • Lacellate Solution should be used right after opening and not saved for a later infusion.
  • Lactated Ringer's and Dextrose and Ringer's should not run through the same set as blood because of clotting risk.
Available strengths 6 strengths
SODIUM CHLORIDE 20 mg/100 mL; SODIUM LACTATE 30 mg/100 mL; POTASSIUM CHLORIDE 600 mg/100 mL; CALCIUM CHLORIDE 310 mg/100 mL SODIUM CHLORIDE 0.6 g/100 mL; SODIUM LACTATE 0.31 g/100 mL; POTASSIUM CHLORIDE 0.03 g/100 mL; CALCIUM CHLORIDE 0.02 g/100 mL SODIUM CHLORIDE 600 mg/100 mL; SODIUM LACTATE 310 mg/100 mL; CALCIUM CHLORIDE 20 mg/100 mL; POTASSIUM CHLORIDE 30 mg/100 mL SODIUM CHLORIDE 600 mg/100 mL; SODIUM LACTATE 310 mg/100 mL; POTASSIUM CHLORIDE 30 mg/100 mL; CALCIUM CHLORIDE 20 mg/100 mL 0.02; 0.03; 0.6; 0.31 g/100 mL; g/100 mL; g/100 mL; g/100 mL 20; 30; 600; 310 mg/100 mL; mg/100 mL; mg/100 mL; mg/100 mL
26 FDA-listed product records ⓘ

Other oral form

Irrigation
Brands Lactated Ringers
Available strengths 5 strengths
SODIUM CHLORIDE 20 mg/100 mL; SODIUM LACTATE 30 mg/100 mL; POTASSIUM CHLORIDE 600 mg/100 mL; CALCIUM CHLORIDE 310 mg/100 mL SODIUM CHLORIDE 0.6 g/100 mL; SODIUM LACTATE 0.31 g/100 mL; POTASSIUM CHLORIDE 0.03 g/100 mL; CALCIUM CHLORIDE 0.02 g/100 mL SODIUM CHLORIDE 600 mg/100 mL; SODIUM LACTATE 310 mg/100 mL; POTASSIUM CHLORIDE 30 mg/100 mL; CALCIUM CHLORIDE 20 mg/100 mL 0.02; 0.03; 0.6; 0.31 g/100 mL; g/100 mL; g/100 mL; g/100 mL 20; 30; 600; 310 mg/100 mL; mg/100 mL; mg/100 mL; mg/100 mL
9 FDA-listed product records ⓘ

Oral solution

Irrigation
Brands Lactated Ringers Irrigation
How this form is used
What it may be used for
  • Lactated Ringer's Irrigation is used for general irrigation, washing and rinsing where a sterile electrolyte solution is suitable.
Important instructions
  • Lactated Ringer's Irrigation dosing depends on the size or surface area being irrigated and the procedure.
Available strengths 1 strength
SODIUM CHLORIDE 600 mg/100 mL; SODIUM LACTATE 310 mg/100 mL; POTASSIUM CHLORIDE 30 mg/100 mL; CALCIUM CHLORIDE 20 mg/100 mL
1 FDA-listed product record ⓘ

Calcium Chloride / Potassium Chloride / Sodium Chloride on the U.S. market: products, makers and brands

How Calcium Chloride / Potassium Chloride / Sodium Chloride appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

8 companies list 16 Calcium Chloride / Potassium Chloride / Sodium Chloride product records with the FDA, mostly as injection, other oral form, oral solution; the earliest marketing or approval year on record is 1971. Brand names on the directory include Lactated Ringers, Lactated Ringers Irrigation; the rest are generics.

3
Dose forms ⓘ
8
Labelers (makers, repackagers, distributors)
2
Brand names
16
FDA-listed product records ⓘ
1971
Earliest FDA record ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

B. Braun Medical Inc.25%
Fresenius Kabi USA, LLC25%
Asclemed USA, Inc.13%
ICU Medical Inc.13%
Baxter Healthcare Company6%
Baxter Healthcare Corporation6%
Other makers13%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

How widely Calcium Chloride / Potassium Chloride / Sodium Chloride is used (Medicaid data)

A general measure of how commonly Calcium Chloride / Potassium Chloride / Sodium Chloride is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Calcium Chloride / Potassium Chloride / Sodium Chloride is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

764,836
Medicaid prescriptions filled (Q1–Q4 2025)
$67.5M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Calcium Chloride / Potassium Chloride / Sodium Chloride prescribed? Of the 1,601 medications we measure, Calcium Chloride / Potassium Chloride / Sodium Chloride ranks #207 by Medicaid prescriptions — more than 87% of them.

Where Calcium Chloride / Potassium Chloride / Sodium Chloride ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #207 of 1,601
#202 Bictegravir, Emtricita... 772,594 Rx #203 Desvenlafaxine 769,380 Rx #204 Fexofenadine 767,005 Rx #205 Fluticasone, Umeclidin... 766,474 Rx #206 Atenolol 765,683 Rx #207 Calcium Chloride / Pot... 764,836 Rx #208 Dupilumab Injection 758,467 Rx #209 Rizatriptan 745,530 Rx #210 Tiotropium Oral Inhala... 739,246 Rx #211 Lacosamide 735,538 Rx #212 Acyclovir 733,721 Rx

Utilization by Calcium Chloride / Potassium Chloride / Sodium Chloride product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

Other Calcium Chloride / Potassium Chloride / Sodium Chloride products — combination packs and listings not yet matched to a specific clinical product (kept visible so every prescription is accounted for)

764,836 Medicaid prescriptions (Q1–Q4 2025) 100% of Calcium Chloride / Potassium Chloride / Sodium Chloride prescriptions shown $67.5M gross reimbursement (before rebates) ≈ $88 per prescription (gross)

Summed across the 19 of 35 listed NDC products with Medicaid activity.

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Calcium Chloride / Potassium Chloride / Sodium Chloride, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 19 of 35 listed Calcium Chloride / Potassium Chloride / Sodium Chloride NDCs with Medicaid activity.

Compare Calcium Chloride / Potassium Chloride / Sodium Chloride products

A representative set of FDA-listed product records for Calcium Chloride / Potassium Chloride / Sodium Chloride — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Strength Route Manufacturer / Labeler Category ⓘ Details
💊Injection
SODIUM CHLORIDE 0.6 g/100 mL; SODIUM LACTATE 0.31 g/100 mL; POTASSIUM CHLORIDE 0.03 g/100 mL; CALCIUM CHLORIDE 0.02 g/100 mL Intravenous Asclemed USA, Inc. NDA View NDC →
SODIUM CHLORIDE 600 mg/100 mL; SODIUM LACTATE 310 mg/100 mL; POTASSIUM CHLORIDE 30 mg/100 mL; CALCIUM CHLORIDE 20 mg/100 mL Intravenous Asclemed USA, Inc. NDA View NDC →
SODIUM CHLORIDE 0.6 g/100 mL; SODIUM LACTATE 0.31 g/100 mL; POTASSIUM CHLORIDE 0.03 g/100 mL; CALCIUM CHLORIDE 0.02 g/100 mL Intravenous B. Braun Medical Inc. × 2 listings NDA View NDC →
SODIUM CHLORIDE 600 mg/100 mL; SODIUM LACTATE 310 mg/100 mL; POTASSIUM CHLORIDE 30 mg/100 mL; CALCIUM CHLORIDE 20 mg/100 mL Intravenous Baxter Healthcare Company NDA View NDC →
SODIUM CHLORIDE 600 mg/100 mL; SODIUM LACTATE 310 mg/100 mL; POTASSIUM CHLORIDE 30 mg/100 mL; CALCIUM CHLORIDE 20 mg/100 mL Intravenous Becton Dickinson and Company ANDA View NDC →
SODIUM CHLORIDE 600 mg/100 mL; SODIUM LACTATE 310 mg/100 mL; POTASSIUM CHLORIDE 30 mg/100 mL; CALCIUM CHLORIDE 20 mg/100 mL Intravenous Fresenius Kabi USA, LLC × 4 listings ANDA View NDC →
SODIUM CHLORIDE 600 mg/100 mL; SODIUM LACTATE 310 mg/100 mL; CALCIUM CHLORIDE 20 mg/100 mL; POTASSIUM CHLORIDE 30 mg/100 mL Intravenous HF Acquisition Co LLC, DBA HealthFirst NDA View NDC →
SODIUM CHLORIDE 600 mg/100 mL; SODIUM LACTATE 310 mg/100 mL; POTASSIUM CHLORIDE 30 mg/100 mL; CALCIUM CHLORIDE 20 mg/100 mL Intravenous ICU Medical Inc. NDA View NDC →
💊Oral solution
SODIUM CHLORIDE 600 mg/100 mL; SODIUM LACTATE 310 mg/100 mL; POTASSIUM CHLORIDE 30 mg/100 mL; CALCIUM CHLORIDE 20 mg/100 mL Irrigation B. Braun Medical Inc. NDA View NDC →
💊Other oral form
SODIUM CHLORIDE 0.6 g/100 mL; SODIUM LACTATE 0.31 g/100 mL; POTASSIUM CHLORIDE 0.03 g/100 mL; CALCIUM CHLORIDE 0.02 g/100 mL Irrigation B. Braun Medical Inc. NDA View NDC →
SODIUM CHLORIDE 20 mg/100 mL; SODIUM LACTATE 30 mg/100 mL; POTASSIUM CHLORIDE 600 mg/100 mL; CALCIUM CHLORIDE 310 mg/100 mL Irrigation Baxter Healthcare Corporation NDA View NDC →
SODIUM CHLORIDE 600 mg/100 mL; SODIUM LACTATE 310 mg/100 mL; POTASSIUM CHLORIDE 30 mg/100 mL; CALCIUM CHLORIDE 20 mg/100 mL Irrigation ICU Medical Inc. NDA View NDC →

Showing 16 of 16 products — FDA National Drug Code Directory. See every product, package size and price: browse all 16 Calcium Chloride / Potassium Chloride / Sodium Chloride NDCs →

Calcium Chloride / Potassium Chloride / Sodium Chloride recall history

A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.

The FDA’s enforcement reports list no Calcium Chloride / Potassium Chloride / Sodium Chloride recalls since July 2021.

✅No Calcium Chloride / Potassium Chloride / Sodium Chloride recalls on record since July 2021

Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Oct 8, 2026.

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one exact multiple-ingredient concept (MIN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). A product with a different ingredient combination belongs on a different page.

Multiple ingredients (MIN) Calcium Chloride / Potassium Chloride / Sodium Chloride RxCUI 1007612 2 dose forms · 2 strengths

Look up RxCUI 1007612 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

💵 What Calcium Chloride / Potassium Chloride / Sodium Chloride costs pharmacies (NADAC benchmark)

The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.

FormStrengthPharmacy acquisition benchmark
Injection, Solution · Intravenous 20; 30; 600; 310 mg/100 mL; mg/100 mL; mg/100 mL; mg/100 mL $0.002–$0.004 per mL NDC details & price history
Injection, Solution · Intravenous SODIUM CHLORIDE 600 mg/100 mL; SODIUM LACTATE 310 mg/100 mL; POTASSIUM CHLORIDE 30 mg/100 mL; CALCIUM CHLORIDE 20 mg/100 mL $0.002–$0.004 per mL NDC details & price history
Injection, Solution · Intravenous SODIUM CHLORIDE 20 mg/100 mL; SODIUM LACTATE 30 mg/100 mL; POTASSIUM CHLORIDE 600 mg/100 mL; CALCIUM CHLORIDE 310 mg/100 mL $0.002–$0.004 per mL NDC details & price history
Why show this? Your out-of-pocket cost depends on insurance, pharmacy markup, and discounts — but the acquisition benchmark tells you whether the medication itself is inexpensive or costly, which strengths cost more per dose, and whether a cash-price quote is in a reasonable range. Each row links to the NDC-level record with its full price history.

Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.

Calcium Chloride / Potassium Chloride / Sodium Chloride brand names

Calcium Chloride / Potassium Chloride / Sodium Chloride is sold under 2 brand names in the FDA directory — Lactated Ringers, Lactated Ringers Irrigation. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

Lactated Ringers Lactated Ringers Irrigation

Who makes Calcium Chloride / Potassium Chloride / Sodium Chloride: manufacturers and labelers

8 companies list Calcium Chloride / Potassium Chloride / Sodium Chloride products with the FDA. By number of product records, the largest are B. Braun Medical Inc., Fresenius Kabi USA, LLC, Asclemed USA, Inc.. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

B. Braun Medical Inc. 4 Fresenius Kabi USA, LLC 4 Asclemed USA, Inc. 2 ICU Medical Inc. 2 Baxter Healthcare Company 1 Baxter Healthcare Corporation 1 Becton Dickinson and Company 1 HF Acquisition Co LLC, DBA HealthFirst 1

Calcium Chloride / Potassium Chloride / Sodium Chloride drug class (RxNorm)

Calcium Chloride / Potassium Chloride / Sodium Chloride belongs to the Calcium class.

Drug family (ATC) Calcium, Electrolyte solutions, Acidifiers

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

Sources for this Calcium Chloride / Potassium Chloride / Sodium Chloride page

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Nov 5, 2025
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Calcium Chloride / Potassium Chloride / Sodium Chloride.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Calcium Chloride / Potassium Chloride / Sodium Chloride after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
19
Finished products in the current FDA directory
16
Companies listing them (makers, repackagers, distributors)
8
FDA labeler codes behind them ⓘ
8
Linked representative label ⓘ
B. Braun Medical Inc.
Linked label effective
Nov 5, 2025
Composite sections available
22
Linked SPL Set ID
d3d29c8f-c326-4097-814a-7f4e08c67068
Linked SPL Document ID
13f7b9a6-d2da-49fe-b7c2-11a4953b2aed
Open the linked representative label on DailyMed ↗

How this page is built

HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. B. Braun Medical Inc. is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →