Cevimeline
Generic name: Pronounced as (se vim' e leen)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 09/15/2016
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Drug interactions
Why is this medication prescribed?
Cevimeline is used to treat the symptoms of dry mouth in patients with Sjogren's syndrome (a condition that affects the immune system and causes dryness of certain parts of the body such as the eyes and mouth). Cevimeline is in a class of medications called cholinergic agonists. It works by increasing the amount of saliva in the mouth.
How should this medicine be used?
Cevimeline comes as a capsule to take by mouth. It is usually taken 3 times a day. Take cevimeline at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cevimeline exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking cevimeline,
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tell your doctor and pharmacist if you are allergic to cevimeline, or any other medications.
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tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: amiodarone (Pacerone, Cordarone); antifungal medications such as ketoconazole (Nizoral) and itraconazole (Sporanox); beta blockers such as acebutolol (Sectral), atenolol (Tenormin), betaxolol (Kerlone), bisoprolol (Zebeta, in Ziac), carvedilol (Coreg), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), pindolol, propranolol (Inderal), sotalol (Betapace), and timolol (Blocadren); bethanechol (Urecholine); bupropion (Wellbutrin, Wellbutrin XL, Wellbutrin SR, Zyban); calcium channel blockers such as diltiazem (Cardizem, Dilacor, Tiazac, others) and verapamil (Calan, Covera, Isoptin, Verelan); chlorpheniramine (Chlor-Trimeton, Aller-Chlor, Teldrin Allergy, others); cimetidine (Tagamet); clarithromycin (Biaxin); clomipramine (Anafranil); duloxetine (Cymbalta); erythromycin (E.E.S., Erythrocin, E-Mycin); fluoxetine (Prozac, Sarafem); fluvoxamine; haloperidol (Haldol); ipratropium (Atrovent); certain medications for HIV such as indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir); medications for Alzheimer's disease, glaucoma, irritable bowel syndrome, motion sickness, Myastenia Gravis, Parkinson's disease, ulcers, or urinary problems; methadone (Dolophine); nefazodone; paroxetine (Paxil, Paxil CR, Pexeva); quinidine; and troleandomycin. Many other medications may also interact with cevimeline, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
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tell your doctor what herbal products you are taking, especially St. John's wort.
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tell your doctor if you have asthma, acute iritis (uveitis; swelling and irritation inside the eye), or glaucoma (an eye disease). Your doctor may tell you not to take cevimeline.
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tell your doctor if you have or have ever had chest pain or a heart attack, chronic bronchitis, chronic obstructive pulmonary disease (COPD; a group of lung diseases that includes chronic bronchitis and emphysema), kidney stones, gallstones or heart disease.
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tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cevimeline, call your doctor.
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if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking cevimeline.
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you should know cevimeline may cause changes in vision, especially at night or when there is not enough light. Use caution when driving at night or performing hazardous activities in reduced lighting.
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you should know that cevimeline may cause you to sweat a great deal, which can cause dehydration. Be sure to drink plenty of water and talk to your doctor about ways to prevent dehydration while taking this medication.
What special dietary instructions should I follow?
Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medication.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
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Cevimeline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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sweating
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nausea
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runny nose
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Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
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severe headache
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changes in vision
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tearing in eyes
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excessive sweating
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difficulty breathing
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abdominal cramping
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changes in heartbeat
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changes in blood pressure
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confusion
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shaking hands that you cannot control
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Cevimeline may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
What OTHER INFORMATION should I know?
Keep all appointments with your doctor.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Delavirdine | Delavirdine The metabolism of Cevimeline can be decreased when combined with Delavirdine. |
Nevirapine | Nevirapine The metabolism of Cevimeline can be decreased when combined with Nevirapine. |
Dolasetron | Dolasetron The metabolism of Dolasetron can be decreased when combined with Cevimeline. |
Cilostazol | Cilostazol Cevimeline may decrease the excretion rate of Cilostazol which could result in a higher serum level. |
Estrogen and Progestin (Oral Contraceptives) | Estrogen and Progestin (Oral Contraceptives) Cevimeline may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level. |
Fenofibrate | Fenofibrate Cevimeline may decrease the excretion rate of Fenofibrate which could result in a higher serum level. |
Guanfacine | Guanfacine Cevimeline may decrease the excretion rate of Guanfacine which could result in a higher serum level. |
Magnesium Hydroxide | Magnesium Hydroxide Cevimeline may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level. |
Mycophenolate | Mycophenolate Cevimeline may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level. |
Olsalazine | Olsalazine Olsalazine may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Penbutolol | Penbutolol The metabolism of Cevimeline can be decreased when combined with Acebutolol. |
Potassium | Potassium Potassium may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Prednisone | Prednisone Cevimeline may decrease the excretion rate of Prednisone which could result in a higher serum level. |
Ranitidine | Ranitidine The metabolism of Ranitidine can be decreased when combined with Cevimeline. |
Reserpine | Reserpine Cevimeline may decrease the excretion rate of Reserpine which could result in a higher serum level. |
Rizatriptan | Rizatriptan Cevimeline may decrease the excretion rate of Rizatriptan which could result in a higher serum level. |
Sumatriptan | Sumatriptan Cevimeline may decrease the excretion rate of Sumatriptan which could result in a higher serum level. |
Tacrolimus | Tacrolimus Tacrolimus may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Ampicillin Injection | Ampicillin Injection Cevimeline may decrease the excretion rate of Ampicillin which could result in a higher serum level. |
Doxycycline Injection | Doxycycline Injection Cevimeline may decrease the excretion rate of Doxycycline which could result in a higher serum level. |
Fluconazole Injection | Fluconazole Injection Cevimeline may decrease the excretion rate of Fluconazole which could result in a higher serum level. |
Foscarnet Injection | Foscarnet Injection Foscarnet may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Hydromorphone Injection | Hydromorphone Injection Cevimeline may decrease the excretion rate of Hydromorphone which could result in a higher serum level. |
Levofloxacin Injection | Levofloxacin Injection Cevimeline may decrease the excretion rate of Levofloxacin which could result in a higher serum level. |
Meperidine Injection | Meperidine Injection Cevimeline may decrease the excretion rate of Meperidine which could result in a higher serum level. |
Metoclopramide Injection | Metoclopramide Injection The metabolism of Cevimeline can be decreased when combined with Metoclopramide. |
Pamidronate Injection | Pamidronate Injection Pamidronic acid may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Vancomycin Injection | Vancomycin Injection Cevimeline may decrease the excretion rate of Vancomycin which could result in a higher serum level. |
Altretamine | Altretamine Amphetamine may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Cefuroxime | Cefuroxime Cefuroxime may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Cyclosporine | Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Cevimeline. |
Ondansetron | Ondansetron The metabolism of Ondansetron can be decreased when combined with Cevimeline. |
Torsemide | Torsemide Torasemide may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Olanzapine | Olanzapine The metabolism of Olanzapine can be decreased when combined with Cevimeline. |
Entacapone | Entacapone The metabolism of Cevimeline can be decreased when combined with Entacapone. |
Hydroxychloroquine | Hydroxychloroquine The metabolism of Cevimeline can be decreased when combined with Hydroxychloroquine. |
Meloxicam | Meloxicam Meloxicam may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Pantoprazole | Pantoprazole Cevimeline may decrease the excretion rate of Pantoprazole which could result in a higher serum level. |
Temozolomide | Temozolomide Cevimeline may decrease the excretion rate of Temozolomide which could result in a higher serum level. |
Zaleplon | Zaleplon Cevimeline may decrease the excretion rate of Zaleplon which could result in a higher serum level. |
Anakinra | Anakinra The metabolism of Cevimeline can be increased when combined with Anakinra. |
Rivastigmine | Rivastigmine The risk or severity of adverse effects can be increased when Rivastigmine is combined with Cevimeline. |
Trimipramine | Trimipramine The metabolism of Trimipramine can be decreased when combined with Cevimeline. |
Etanercept Injection | Etanercept Injection The metabolism of Cevimeline can be increased when combined with Etanercept. |
Perindopril | Perindopril Cevimeline may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Tenofovir | Tenofovir Tenofovir may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Choline Magnesium Trisalicylate | Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Eplerenone | Eplerenone Eplerenone may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Escitalopram | Escitalopram The serum concentration of Cevimeline can be increased when it is combined with Escitalopram. |
Zonisamide | Zonisamide Cevimeline may increase the excretion rate of Zonisamide which could result in a lower serum level and potentially a reduction in efficacy. |
Adalimumab Injection | Adalimumab Injection The metabolism of Cevimeline can be increased when combined with Adalimumab. |
Aripiprazole | Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Cevimeline. |
Atomoxetine | Atomoxetine Cevimeline may decrease the excretion rate of Atomoxetine which could result in a higher serum level. |
Atazanavir | Atazanavir Atazanavir may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Almotriptan | Almotriptan Cevimeline may decrease the excretion rate of Almotriptan which could result in a higher serum level. |
Eletriptan | Eletriptan The metabolism of Eletriptan can be decreased when combined with Cevimeline. |
Mefloquine | Mefloquine The risk or severity of adverse effects can be increased when Mefloquine is combined with Cevimeline. |
Emtricitabine | Emtricitabine Cevimeline may decrease the excretion rate of Emtricitabine which could result in a higher serum level. |
Memantine | Memantine Cevimeline may decrease the excretion rate of Memantine which could result in a higher serum level. |
Tegaserod | Tegaserod The metabolism of Cevimeline can be decreased when combined with Tegaserod. |
Tadalafil | Tadalafil Cevimeline may decrease the excretion rate of Tadalafil which could result in a higher serum level. |
Progesterone | Progesterone The metabolism of Progesterone can be decreased when combined with Cevimeline. |
Infliximab Injection | Infliximab Injection The metabolism of Cevimeline can be increased when combined with Infliximab. |
Protriptyline | Protriptyline The metabolism of Protriptyline can be decreased when combined with Cevimeline. |
Duloxetine | Duloxetine The metabolism of Duloxetine can be decreased when combined with Cevimeline. |
Tinidazole | Tinidazole Cevimeline may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
Trospium | Trospium The metabolism of Cevimeline can be decreased when combined with Trospium. |
Cefditoren | Cefditoren Cevimeline may decrease the excretion rate of Cefdinir which could result in a higher serum level. |
Cinacalcet | Cinacalcet The metabolism of Cevimeline can be decreased when combined with Cinacalcet. |
Cyanocobalamin Injection | Cyanocobalamin Injection Cevimeline may decrease the excretion rate of Hydroxocobalamin which could result in a higher serum level. |
Erlotinib | Erlotinib The metabolism of Erlotinib can be decreased when combined with Cevimeline. |
Eszopiclone | Eszopiclone Cevimeline may decrease the excretion rate of Eszopiclone which could result in a higher serum level. |
Ganciclovir | Ganciclovir Cevimeline may decrease the excretion rate of Ganciclovir which could result in a higher serum level. |
Ribavirin | Ribavirin Cevimeline may decrease the excretion rate of Ribavirin which could result in a higher serum level. |
Solifenacin | Solifenacin The metabolism of Solifenacin can be decreased when combined with Cevimeline. |
Valganciclovir | Valganciclovir Cevimeline may decrease the excretion rate of Valganciclovir which could result in a higher serum level. |
Adefovir | Adefovir Adefovir may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Dextroamphetamine | Dextroamphetamine Amphetamine may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Peginterferon Alfa-2b (PEG-Intron) | Peginterferon Alfa-2b (PEG-Intron) The metabolism of Cevimeline can be decreased when combined with Peginterferon alfa-2b. |
Ramelteon | Ramelteon Cevimeline may decrease the excretion rate of Ramelteon which could result in a higher serum level. |
Darifenacin | Darifenacin The metabolism of Darifenacin can be decreased when combined with Cevimeline. |
Fentanyl | Fentanyl Cevimeline may decrease the excretion rate of Fentanyl which could result in a higher serum level. |
Pregabalin | Pregabalin Cevimeline may decrease the excretion rate of Pregabalin which could result in a higher serum level. |
Tipranavir | Tipranavir The metabolism of Tipranavir can be decreased when combined with Cevimeline. |
Ranolazine | Ranolazine The serum concentration of Cevimeline can be increased when it is combined with Ranolazine. |
Abatacept Injection | Abatacept Injection The metabolism of Cevimeline can be increased when combined with Abatacept. |
Rasagiline | Rasagiline Cevimeline may decrease the excretion rate of Rasagiline which could result in a higher serum level. |
Imatinib | Imatinib The metabolism of Cevimeline can be decreased when combined with Imatinib. |
Sitagliptin | Sitagliptin Cevimeline may decrease the excretion rate of Sitagliptin which could result in a higher serum level. |
Varenicline | Varenicline Cevimeline may decrease the excretion rate of Varenicline which could result in a higher serum level. |
Gefitinib | Gefitinib The metabolism of Cevimeline can be decreased when combined with Gefitinib. |
Albuterol | Albuterol Cevimeline may decrease the excretion rate of Salbutamol which could result in a higher serum level. |
Paliperidone | Paliperidone Cevimeline may decrease the excretion rate of Paliperidone which could result in a higher serum level. |
Bortezomib | Bortezomib The metabolism of Bortezomib can be decreased when combined with Cevimeline. |
Clofarabine Injection | Clofarabine Injection Cevimeline may decrease the excretion rate of Clofarabine which could result in a higher serum level. |
Lubiprostone | Lubiprostone Cevimeline may decrease the excretion rate of Lubiprostone which could result in a higher serum level. |
Primaquine | Primaquine The metabolism of Cevimeline can be decreased when combined with Primaquine. |
Pemetrexed Injection | Pemetrexed Injection Cevimeline may decrease the excretion rate of Pemetrexed which could result in a higher serum level. |
Lisdexamfetamine | Lisdexamfetamine The metabolism of Cevimeline can be decreased when combined with Lisdexamfetamine. |
Sorafenib | Sorafenib The metabolism of Sorafenib can be decreased when combined with Cevimeline. |
Levocetirizine | Levocetirizine Cevimeline may decrease the excretion rate of Levocetirizine which could result in a higher serum level. |
Pegaptanib Injection | Pegaptanib Injection Cevimeline may decrease the excretion rate of Pegaptanib which could result in a higher serum level. |
Mexiletine | Mexiletine The metabolism of Mexiletine can be decreased when combined with Cevimeline. |
Azacitidine Injection | Azacitidine Injection Cevimeline may decrease the excretion rate of Azacitidine which could result in a higher serum level. |
Temsirolimus | Temsirolimus The metabolism of Cevimeline can be decreased when combined with Temsirolimus. |
Lenalidomide | Lenalidomide Cevimeline may decrease the excretion rate of Lenalidomide which could result in a higher serum level. |
Nilotinib | Nilotinib The metabolism of Cevimeline can be decreased when combined with Nilotinib. |
Budesonide | Budesonide Cevimeline may decrease the excretion rate of Budesonide which could result in a higher serum level. |
Desmopressin | Desmopressin Desmopressin may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Betaine | Betaine The risk or severity of adverse effects can be increased when Glycine betaine is combined with Cevimeline. |
Doripenem Injection | Doripenem Injection Cevimeline may decrease the excretion rate of Doripenem which could result in a higher serum level. |
Arsenic Trioxide Injection | Arsenic Trioxide Injection Cevimeline may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level. |
Desvenlafaxine | Desvenlafaxine Cevimeline may decrease the excretion rate of Desvenlafaxine which could result in a higher serum level. |
Nebivolol | Nebivolol The risk or severity of adverse effects can be increased when Nebivolol is combined with Cevimeline. |
Flecainide | Flecainide The metabolism of Flecainide can be decreased when combined with Cevimeline. |
Certolizumab Injection | Certolizumab Injection The metabolism of Certolizumab pegol can be increased when combined with Cevimeline. |
Daptomycin Injection | Daptomycin Injection Daptomycin may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Methylnaltrexone Injection | Methylnaltrexone Injection Cevimeline may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level. |
Midazolam | Midazolam Cevimeline may decrease the excretion rate of Midazolam which could result in a higher serum level. |
Dexrazoxane Injection | Dexrazoxane Injection Cevimeline may decrease the excretion rate of Dexrazoxane which could result in a higher serum level. |
Milnacipran | Milnacipran Cevimeline may decrease the excretion rate of Milnacipran which could result in a higher serum level. |
Plerixafor Injection | Plerixafor Injection Cevimeline may decrease the excretion rate of Plerixafor which could result in a higher serum level. |
Fesoterodine | Fesoterodine Cevimeline may decrease the excretion rate of Fesoterodine which could result in a higher serum level. |
Betaxolol | Betaxolol The risk or severity of adverse effects can be increased when Betaxolol is combined with Cevimeline. |
Iloperidone | Iloperidone The metabolism of Iloperidone can be decreased when combined with Cevimeline. |
Prasugrel | Prasugrel Cevimeline may decrease the excretion rate of Prasugrel which could result in a higher serum level. |
Everolimus | Everolimus The metabolism of Cevimeline can be decreased when combined with Everolimus. |
Tolvaptan (low blood sodium) | Tolvaptan (low blood sodium) Tolvaptan may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Dronedarone | Dronedarone The metabolism of Dronedarone can be decreased when combined with Cevimeline. |
Pralatrexate Injection | Pralatrexate Injection Cevimeline may decrease the excretion rate of Pralatrexate which could result in a higher serum level. |
Palonosetron Injection | Palonosetron Injection Cevimeline may decrease the excretion rate of Palonosetron which could result in a higher serum level. |
Saxagliptin | Saxagliptin Cevimeline may decrease the excretion rate of Saxagliptin which could result in a higher serum level. |
Telavancin Injection | Telavancin Injection Cevimeline may decrease the excretion rate of Telavancin which could result in a higher serum level. |
Tapentadol | Tapentadol The metabolism of Cevimeline can be decreased when combined with Tapentadol. |
Topotecan | Topotecan Cevimeline may decrease the excretion rate of Topotecan which could result in a higher serum level. |
Golimumab Injection | Golimumab Injection The metabolism of Cevimeline can be increased when combined with Golimumab. |
Pazopanib | Pazopanib The metabolism of Cevimeline can be decreased when combined with Pazopanib. |
Oxymorphone | Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Cevimeline. |
Tocilizumab Injection | Tocilizumab Injection The metabolism of Cevimeline can be increased when combined with Tocilizumab. |
Dalfampridine | Dalfampridine Cevimeline may decrease the excretion rate of Dalfampridine which could result in a higher serum level. |
Ceftaroline Injection | Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Acetaminophen Injection | Acetaminophen Injection Cevimeline may decrease the excretion rate of Acetaminophen which could result in a higher serum level. |
Vilazodone | Vilazodone The metabolism of Cevimeline can be decreased when combined with Vilazodone. |
Ipilimumab Injection | Ipilimumab Injection Cevimeline may decrease the excretion rate of Ipilimumab which could result in a higher serum level. |
Denileukin Diftitox Injection | Denileukin Diftitox Injection Aldesleukin may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Terbutaline Injection | Terbutaline Injection Cevimeline may decrease the excretion rate of Terbutaline which could result in a higher serum level. |
Roflumilast | Roflumilast Cevimeline may decrease the excretion rate of Roflumilast which could result in a higher serum level. |
Rilpivirine | Rilpivirine The metabolism of Cevimeline can be decreased when combined with Rilpivirine. |
Abiraterone | Abiraterone The metabolism of Cevimeline can be decreased when combined with Abiraterone. |
Rivaroxaban | Rivaroxaban Cevimeline may decrease the excretion rate of Rivaroxaban which could result in a higher serum level. |
Ruxolitinib | Ruxolitinib Cevimeline may decrease the excretion rate of Ruxolitinib which could result in a higher serum level. |
Clobazam | Clobazam The metabolism of Clobazam can be decreased when combined with Cevimeline. |
Vemurafenib | Vemurafenib The metabolism of Cevimeline can be decreased when combined with Vemurafenib. |
Deferiprone | Deferiprone Cevimeline may decrease the excretion rate of Deferiprone which could result in a higher serum level. |
Naloxone Injection | Naloxone Injection Cevimeline may decrease the excretion rate of Naloxone which could result in a higher serum level. |
Fondaparinux Injection | Fondaparinux Injection Cevimeline may decrease the excretion rate of Fondaparinux which could result in a higher serum level. |
Enzalutamide | Enzalutamide Cevimeline may decrease the excretion rate of Enzalutamide which could result in a higher serum level. |
Mirabegron | Mirabegron The metabolism of Mirabegron can be decreased when combined with Cevimeline. |
Teduglutide Injection | Teduglutide Injection Cevimeline may decrease the excretion rate of Teduglutide which could result in a higher serum level. |
Alogliptin | Alogliptin Cevimeline may decrease the excretion rate of Alogliptin which could result in a higher serum level. |
Ponatinib | Ponatinib The metabolism of Ponatinib can be decreased when combined with Cevimeline. |
Pomalidomide | Pomalidomide Cevimeline may decrease the excretion rate of Pomalidomide which could result in a higher serum level. |
Canagliflozin | Canagliflozin Cevimeline may increase the excretion rate of Canagliflozin which could result in a lower serum level and potentially a reduction in efficacy. |
Methazolamide | Methazolamide Methazolamide may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Ospemifene | Ospemifene The metabolism of Cevimeline can be decreased when combined with Ospemifene. |
Trametinib | Trametinib Cevimeline may decrease the excretion rate of Trametinib which could result in a higher serum level. |
Levomilnacipran | Levomilnacipran Cevimeline may decrease the excretion rate of Levomilnacipran which could result in a higher serum level. |
Ertapenem Injection | Ertapenem Injection Cevimeline may decrease the excretion rate of Ertapenem which could result in a higher serum level. |
Vortioxetine | Vortioxetine Cevimeline may decrease the excretion rate of Vortioxetine which could result in a higher serum level. |
Ibrutinib | Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Cevimeline. |
Ketorolac Injection | Ketorolac Injection Ketorolac may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Sofosbuvir | Sofosbuvir Cevimeline may decrease the excretion rate of Sofosbuvir which could result in a higher serum level. |
Dapagliflozin | Dapagliflozin Dapagliflozin may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Apremilast | Apremilast The metabolism of Apremilast can be increased when combined with Cevimeline. |
Droxidopa | Droxidopa Cevimeline may decrease the excretion rate of Droxidopa which could result in a higher serum level. |
Siltuximab Injection | Siltuximab Injection The metabolism of Cevimeline can be increased when combined with Siltuximab. |
Testosterone Injection | Testosterone Injection Cevimeline may decrease the excretion rate of Testosterone which could result in a higher serum level. |
Oritavancin Injection | Oritavancin Injection The metabolism of Cevimeline can be decreased when combined with Oritavancin. |
Edoxaban | Edoxaban Cevimeline may decrease the excretion rate of Edoxaban which could result in a higher serum level. |
Methamphetamine | Methamphetamine Cevimeline may decrease the excretion rate of Metamfetamine which could result in a higher serum level. |
Tasimelteon | Tasimelteon Cevimeline may decrease the excretion rate of Tasimelteon which could result in a higher serum level. |
Secukinumab Injection | Secukinumab Injection The metabolism of Cevimeline can be increased when combined with Secukinumab. |
Risperidone Injection | Risperidone Injection The metabolism of Risperidone can be decreased when combined with Cevimeline. |
Lenvatinib | Lenvatinib The metabolism of Cevimeline can be decreased when combined with Lenvatinib. |
Naloxegol | Naloxegol The metabolism of Cevimeline can be decreased when combined with Naloxegol. |
Panobinostat | Panobinostat The metabolism of Cevimeline can be decreased when combined with Panobinostat. |
Haloperidol Injection | Haloperidol Injection The serum concentration of Cevimeline can be increased when it is combined with Haloperidol. |
Amiloride | Amiloride Amiloride may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Macitentan | Macitentan Cevimeline may decrease the excretion rate of Macitentan which could result in a higher serum level. |
Rolapitant | Rolapitant The metabolism of Cevimeline can be decreased when combined with Rolapitant. |
Brexpiprazole | Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Cevimeline. |
Cariprazine | Cariprazine The metabolism of Cariprazine can be decreased when combined with Cevimeline. |
Penicillin G Procaine Injection | Penicillin G Procaine Injection Cevimeline may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level. |
Trabectedin Injection | Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Cevimeline. |
Ixazomib | Ixazomib Cevimeline may decrease the excretion rate of Ixazomib which could result in a higher serum level. |
Lesinurad | Lesinurad Cevimeline may decrease the excretion rate of Lesinurad which could result in a higher serum level. |
Amphotericin B Liposomal Injection | Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Brivaracetam Injection | Brivaracetam Injection Cevimeline may decrease the excretion rate of Brivaracetam which could result in a higher serum level. |
Cobicistat | Cobicistat The metabolism of Cevimeline can be decreased when combined with Cobicistat. |
Diphenhydramine Injection | Diphenhydramine Injection The metabolism of Cevimeline can be decreased when combined with Diphenhydramine. |
Furosemide Injection | Furosemide Injection Cevimeline may increase the excretion rate of Furosemide which could result in a lower serum level and potentially a reduction in efficacy. |
Rucaparib | Rucaparib The metabolism of Cevimeline can be decreased when combined with Rucaparib. |
Lixisenatide Injection | Lixisenatide Injection Cevimeline may decrease the excretion rate of Lixisenatide which could result in a higher serum level. |
Doxepin (Insomnia) | Doxepin (Insomnia) The metabolism of Cevimeline can be decreased when combined with Doxepin. |
Deutetrabenazine | Deutetrabenazine Cevimeline may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level. |
Valbenazine | Valbenazine Cevimeline may decrease the excretion rate of Valbenazine which could result in a higher serum level. |
Safinamide | Safinamide The metabolism of Cevimeline can be decreased when combined with Safinamide. |
Naldemedine | Naldemedine Cevimeline may decrease the excretion rate of Naldemedine which could result in a higher serum level. |
Midostaurin | Midostaurin The metabolism of Cevimeline can be decreased when combined with Midostaurin. |
Enasidenib | Enasidenib The metabolism of Cevimeline can be decreased when combined with Enasidenib. |
Benznidazole | Benznidazole Cevimeline may decrease the excretion rate of Benznidazole which could result in a higher serum level. |
Delafloxacin | Delafloxacin Cevimeline may decrease the excretion rate of Delafloxacin which could result in a higher serum level. |
Letermovir | Letermovir The metabolism of Letermovir can be decreased when combined with Cevimeline. |
Tetrabenazine | Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Cevimeline. |
Ertugliflozin | Ertugliflozin Ertugliflozin may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Buprenorphine Injection | Buprenorphine Injection The metabolism of Cevimeline can be decreased when combined with Buprenorphine. |
Apalutamide | Apalutamide Cevimeline may decrease the excretion rate of Apalutamide which could result in a higher serum level. |
Baricitinib | Baricitinib Cevimeline may decrease the excretion rate of Baricitinib which could result in a higher serum level. |
Lofexidine | Lofexidine Cevimeline may decrease the excretion rate of Lofexidine which could result in a higher serum level. |
Plazomicin Injection | Plazomicin Injection Cevimeline may decrease the excretion rate of Plazomicin which could result in a higher serum level. |
Eliglustat | Eliglustat The metabolism of Cevimeline can be decreased when combined with Eliglustat. |
Encorafenib | Encorafenib The metabolism of Encorafenib can be decreased when combined with Cevimeline. |
Elagolix | Elagolix The metabolism of Elagolix can be decreased when combined with Cevimeline. |
Tafenoquine | Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Cevimeline. |
Cannabidiol | Cannabidiol The metabolism of Cannabidiol can be decreased when combined with Cevimeline. |
Dacomitinib | Dacomitinib The metabolism of Cevimeline can be decreased when combined with Dacomitinib. |
Stiripentol | Stiripentol The metabolism of Cevimeline can be decreased when combined with Stiripentol. |
Rifamycin | Rifamycin The metabolism of Cevimeline can be decreased when combined with Rifamycin. |
Prucalopride | Prucalopride Cevimeline may decrease the excretion rate of Prucalopride which could result in a higher serum level. |
Emapalumab-lzsg Injection | Emapalumab-lzsg Injection The metabolism of Cevimeline can be increased when combined with Emapalumab. |
Acyclovir Ophthalmic | Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Solriamfetol | Solriamfetol Cevimeline may decrease the excretion rate of Solriamfetol which could result in a higher serum level. |
Triclabendazole | Triclabendazole The metabolism of Cevimeline can be decreased when combined with Triclabendazole. |
Istradefylline | Istradefylline The metabolism of Istradefylline can be decreased when combined with Cevimeline. |
Pitolisant | Pitolisant The serum concentration of Cevimeline can be decreased when it is combined with Pitolisant. |
Fedratinib | Fedratinib The metabolism of Cevimeline can be decreased when combined with Fedratinib. |
Phenytoin Injection | Phenytoin Injection The metabolism of Phenytoin can be decreased when combined with Cevimeline. |
Cenobamate | Cenobamate The serum concentration of Cevimeline can be decreased when it is combined with Cenobamate. |
Tucatinib | Tucatinib The metabolism of Tucatinib can be decreased when combined with Cevimeline. |
Fenfluramine | Fenfluramine The metabolism of Cevimeline can be decreased when combined with Fenfluramine. |
Satralizumab-mwge Injection | Satralizumab-mwge Injection The serum concentration of Cevimeline can be decreased when it is combined with Satralizumab. |
Progestin-Only (drospirenone) Oral Contraceptives | Progestin-Only (drospirenone) Oral Contraceptives Drospirenone may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Viloxazine | Viloxazine Cevimeline may decrease the excretion rate of Viloxazine which could result in a higher serum level. |
Tobramycin Injection | Tobramycin Injection Tobramycin may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Theophylline | Theophylline The metabolism of Theophylline can be decreased when combined with Cevimeline. |
Fenoprofen | Fenoprofen Fenoprofen may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Indomethacin | Indomethacin Indomethacin may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Mefenamic Acid | Mefenamic Acid Mefenamic acid may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Naproxen | Naproxen Naproxen may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Tolmetin | Tolmetin Tolmetin may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Sulindac | Sulindac Sulindac may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Trazodone | Trazodone The metabolism of Cevimeline can be decreased when combined with Trazodone. |
Isotretinoin | Isotretinoin Cevimeline may decrease the excretion rate of Isotretinoin which could result in a higher serum level. |
Sucralfate | Sucralfate Cevimeline may decrease the excretion rate of Sucralfate which could result in a higher serum level. |
Hydroxyurea | Hydroxyurea The metabolism of Cevimeline can be decreased when combined with Hydroxyurea. |
Floxuridine | Floxuridine Cevimeline may decrease the excretion rate of Floxuridine which could result in a higher serum level. |
Metaxalone | Metaxalone Cevimeline may decrease the excretion rate of Metaxalone which could result in a higher serum level. |
Methotrexate Injection | Methotrexate Injection Methotrexate may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Chlorpromazine | Chlorpromazine The metabolism of Chlorpromazine can be decreased when combined with Cevimeline. |
Diazepam | Diazepam Cevimeline may decrease the excretion rate of Diazepam which could result in a higher serum level. |
Oxazepam | Oxazepam Cevimeline may decrease the excretion rate of Oxazepam which could result in a higher serum level. |
Flurazepam | Flurazepam Cevimeline may decrease the excretion rate of Flurazepam which could result in a higher serum level. |
Clorazepate | Clorazepate Cevimeline may decrease the excretion rate of Clorazepic acid which could result in a higher serum level. |
Lorazepam | Lorazepam Cevimeline may decrease the excretion rate of Lorazepam which could result in a higher serum level. |
Carmustine | Carmustine Cevimeline may decrease the excretion rate of Carmustine which could result in a higher serum level. |
Amantadine | Amantadine Cevimeline may decrease the excretion rate of Amantadine which could result in a higher serum level. |
Codeine | Codeine Cevimeline may decrease the excretion rate of Codeine which could result in a higher serum level. |
Tranylcypromine | Tranylcypromine The metabolism of Cevimeline can be decreased when combined with Tranylcypromine. |
Phenelzine | Phenelzine The metabolism of Phenelzine can be decreased when combined with Cevimeline. |
Tetracycline | Tetracycline Cevimeline may decrease the excretion rate of Tetracycline which could result in a higher serum level. |
Prochlorperazine | Prochlorperazine The metabolism of Prochlorperazine can be decreased when combined with Cevimeline. |
Thioridazine | Thioridazine The metabolism of Cevimeline can be decreased when combined with Thioridazine. |
Bleomycin | Bleomycin Cevimeline may decrease the excretion rate of Bleomycin which could result in a higher serum level. |
Sulfadiazine | Sulfadiazine Cevimeline may decrease the excretion rate of Sulfadiazine which could result in a higher serum level. |
Oxycodone | Oxycodone The metabolism of Oxycodone can be decreased when combined with Cevimeline. |
Methadone | Methadone The metabolism of Cevimeline can be decreased when combined with Methadone. |
Oxybutynin | Oxybutynin The metabolism of Cevimeline can be decreased when combined with Oxybutynin. |
Benztropine | Benztropine Cevimeline may decrease the excretion rate of Benzatropine which could result in a higher serum level. |
Maprotiline | Maprotiline Cevimeline may decrease the excretion rate of Maprotiline which could result in a higher serum level. |
Ibuprofen | Ibuprofen Ibuprofen may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Orphenadrine | Orphenadrine The metabolism of Cevimeline can be decreased when combined with Orphenadrine. |
Perphenazine | Perphenazine The metabolism of Cevimeline can be decreased when combined with Perphenazine. |
Azathioprine | Azathioprine Cevimeline may decrease the excretion rate of Azathioprine which could result in a higher serum level. |
Fluphenazine | Fluphenazine The metabolism of Cevimeline can be decreased when combined with Fluphenazine. |
Methylphenidate | Methylphenidate Cevimeline may decrease the excretion rate of Methylphenidate which could result in a higher serum level. |
Amoxapine | Amoxapine The metabolism of Cevimeline can be decreased when combined with Amoxapine. |
Sulfasalazine | Sulfasalazine Sulfasalazine may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Doxorubicin | Doxorubicin The metabolism of Cevimeline can be decreased when combined with Doxorubicin. |
Mechlorethamine | Mechlorethamine The risk or severity of adverse effects can be increased when Mechlorethamine is combined with Cevimeline. |
Pyridostigmine | Pyridostigmine The risk or severity of adverse effects can be increased when Pyridostigmine is combined with Cevimeline. |
Phenazopyridine | Phenazopyridine Phenazopyridine may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Carbamazepine | Carbamazepine Cevimeline may decrease the excretion rate of Carbamazepine which could result in a higher serum level. |
Methyldopa | Methyldopa Cevimeline may decrease the excretion rate of Methyldopa which could result in a higher serum level. |
Clonidine | Clonidine The metabolism of Clonidine can be decreased when combined with Cevimeline. |
Hydralazine | Hydralazine Cevimeline may decrease the excretion rate of Hydralazine which could result in a higher serum level. |
Cimetidine | Cimetidine The metabolism of Cimetidine can be decreased when combined with Cevimeline. |
Gentamicin Injection | Gentamicin Injection Gentamicin may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Warfarin | Warfarin Cevimeline may decrease the excretion rate of Warfarin which could result in a higher serum level. |
Clonazepam | Clonazepam Cevimeline may decrease the excretion rate of Clonazepam which could result in a higher serum level. |
Loperamide | Loperamide The metabolism of Loperamide can be decreased when combined with Cevimeline. |
Promethazine | Promethazine The metabolism of Cevimeline can be decreased when combined with Promethazine. |
Meclofenamate | Meclofenamate Meclofenamic acid may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Nitrofurantoin | Nitrofurantoin Cevimeline may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level. |
Digoxin | Digoxin Cevimeline may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Chloroquine | Chloroquine The metabolism of Chloroquine can be decreased when combined with Cevimeline. |
Quinine | Quinine The metabolism of Cevimeline can be decreased when combined with Quinine. |
Triamterene | Triamterene Triamterene may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Chlorothiazide | Chlorothiazide Chlorothiazide may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Chlorthalidone | Chlorthalidone Chlorthalidone may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Metolazone | Metolazone Cevimeline may increase the excretion rate of Metolazone which could result in a lower serum level and potentially a reduction in efficacy. |
Isosorbide | Isosorbide Isosorbide may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Secobarbital | Secobarbital Cevimeline may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Desipramine | Desipramine The metabolism of Desipramine can be decreased when combined with Cevimeline. |
Amitriptyline | Amitriptyline The metabolism of Cevimeline can be decreased when combined with Amitriptyline. |
Imipramine | Imipramine The metabolism of Imipramine can be decreased when combined with Cevimeline. |
Probenecid | Probenecid Cevimeline may decrease the excretion rate of Probenecid which could result in a higher serum level. |
Quinidine | Quinidine The metabolism of Cevimeline can be decreased when combined with Quinidine. |
Procainamide | Procainamide The metabolism of Procainamide can be decreased when combined with Cevimeline. |
Isoniazid | Isoniazid Cevimeline may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Pyrazinamide | Pyrazinamide Cevimeline may decrease the excretion rate of Pyrazinamide which could result in a higher serum level. |
Disopyramide | Disopyramide Cevimeline may decrease the excretion rate of Disopyramide which could result in a higher serum level. |
Tamoxifen | Tamoxifen The metabolism of Cevimeline can be decreased when combined with Tamoxifen. |
Butabarbital | Butabarbital Cevimeline may decrease the excretion rate of Butabarbital which could result in a higher serum level. |
Liothyronine | Liothyronine Cevimeline may decrease the excretion rate of Liothyronine which could result in a higher serum level. |
Methimazole | Methimazole The metabolism of Cevimeline can be decreased when combined with Methimazole. |
Chlorpropamide | Chlorpropamide Cevimeline may decrease the excretion rate of Chlorpropamide which could result in a higher serum level. |
Tolbutamide | Tolbutamide Cevimeline may decrease the excretion rate of Tolbutamide which could result in a higher serum level. |
Tolazamide | Tolazamide Cevimeline may decrease the excretion rate of Tolazamide which could result in a higher serum level. |
Dextromethorphan | Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Cevimeline. |
Niacin | Niacin The metabolism of Cevimeline can be decreased when combined with Niacin. |
Baclofen | Baclofen Baclofen may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Clemastine | Clemastine The metabolism of Cevimeline can be decreased when combined with Clemastine. |
Chlorpheniramine | Chlorpheniramine The metabolism of Cevimeline can be decreased when combined with Chlorpheniramine. |
Meclizine | Meclizine The metabolism of Meclizine can be decreased when combined with Cevimeline. |
Ethambutol | Ethambutol Cevimeline may decrease the excretion rate of Ethambutol which could result in a higher serum level. |
Methyclothiazide | Methyclothiazide Methyclothiazide may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Hydrochlorothiazide | Hydrochlorothiazide Hydrochlorothiazide may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Chlorzoxazone | Chlorzoxazone Cevimeline may decrease the excretion rate of Chlorzoxazone which could result in a higher serum level. |
Pyridoxine | Pyridoxine Pyridoxine may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Folic Acid | Folic Acid Folic acid may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) The risk or severity of adverse effects can be increased when Cevimeline is combined with Propranolol. |
Nortriptyline | Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Cevimeline. |
Spironolactone | Spironolactone Spironolactone may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Amphotericin B Injection | Amphotericin B Injection Amphotericin B may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Phytonadione | Phytonadione Cevimeline may decrease the excretion rate of Phylloquinone which could result in a higher serum level. |
Amikacin Injection | Amikacin Injection Amikacin may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Nadolol | Nadolol The risk or severity of adverse effects can be increased when Cevimeline is combined with Nadolol. |
Allopurinol | Allopurinol Cevimeline may decrease the excretion rate of Allopurinol which could result in a higher serum level. |
Flavoxate | Flavoxate Cevimeline may decrease the excretion rate of Flavoxate which could result in a higher serum level. |
Colchicine | Colchicine Cevimeline may decrease the excretion rate of Colchicine which could result in a higher serum level. |
Cefaclor | Cefaclor Cefaclor may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Cefadroxil | Cefadroxil Cefadroxil may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Cefazolin Injection | Cefazolin Injection Cefazolin may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Cephalexin | Cephalexin Cephalexin may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Cefoxitin Injection | Cefoxitin Injection Cefoxitin may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Dacarbazine | Dacarbazine Cevimeline may decrease the excretion rate of Dacarbazine which could result in a higher serum level. |
Acetazolamide | Acetazolamide Acetazolamide may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Cefotaxime Injection | Cefotaxime Injection Cefotaxime may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Calcitonin Salmon Injection | Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Ketoconazole | Ketoconazole The metabolism of Cevimeline can be decreased when combined with Ketoconazole. |
Pyrantel | Pyrantel Cevimeline may decrease the excretion rate of Pyrantel which could result in a higher serum level. |
Thiotepa Injection | Thiotepa Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Cevimeline. |
Vinblastine | Vinblastine The metabolism of Cevimeline can be decreased when combined with Vinblastine. |
Ethacrynic Acid | Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Colistimethate Injection | Colistimethate Injection Colistimethate may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Metoprolol | Metoprolol The metabolism of Metoprolol can be decreased when combined with Cevimeline. |
Hydroxyzine | Hydroxyzine The metabolism of Cevimeline can be decreased when combined with Hydroxyzine. |
Aspirin | Aspirin Acetylsalicylic acid may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Salsalate | Salsalate Salsalate may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Alprazolam | Alprazolam Cevimeline may decrease the excretion rate of Alprazolam which could result in a higher serum level. |
Temazepam | Temazepam Cevimeline may decrease the excretion rate of Temazepam which could result in a higher serum level. |
Triazolam | Triazolam Cevimeline may decrease the excretion rate of Triazolam which could result in a higher serum level. |
Dicyclomine | Dicyclomine Cevimeline may decrease the excretion rate of Dicyclomine which could result in a higher serum level. |
Propantheline | Propantheline Cevimeline may decrease the excretion rate of Propantheline which could result in a higher serum level. |
Trimethoprim | Trimethoprim Cevimeline may decrease the excretion rate of Trimethoprim which could result in a higher serum level. |
Diltiazem | Diltiazem The metabolism of Diltiazem can be decreased when combined with Cevimeline. |
Nifedipine | Nifedipine The metabolism of Nifedipine can be decreased when combined with Cevimeline. |
Timolol | Timolol The risk or severity of adverse effects can be increased when Cevimeline is combined with Timolol. |
Verapamil | Verapamil The metabolism of Verapamil can be decreased when combined with Cevimeline. |
Atenolol | Atenolol The risk or severity of adverse effects can be increased when Atenolol is combined with Cevimeline. |
Pindolol | Pindolol The risk or severity of adverse effects can be increased when Cevimeline is combined with Pindolol. |
Cisplatin Injection | Cisplatin Injection Cevimeline may decrease the excretion rate of Cisplatin which could result in a higher serum level. |
Diflunisal | Diflunisal Diflunisal may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Piroxicam | Piroxicam Piroxicam may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Bumetanide | Bumetanide Cevimeline may increase the excretion rate of Bumetanide which could result in a lower serum level and potentially a reduction in efficacy. |
Glipizide | Glipizide Cevimeline may decrease the excretion rate of Glipizide which could result in a higher serum level. |
Indapamide | Indapamide Cevimeline may increase the excretion rate of Indapamide which could result in a lower serum level and potentially a reduction in efficacy. |
Amoxicillin | Amoxicillin Cevimeline may decrease the excretion rate of Amoxicillin which could result in a higher serum level. |
Oxacillin Injection | Oxacillin Injection Cevimeline may decrease the excretion rate of Oxacillin which could result in a higher serum level. |
Pentoxifylline | Pentoxifylline Cevimeline may decrease the excretion rate of Pentoxifylline which could result in a higher serum level. |
Pentamidine Injection | Pentamidine Injection Pentamidine may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Ceftriaxone Injection | Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Labetalol | Labetalol The metabolism of Cevimeline can be decreased when combined with Labetalol. |
Auranofin | Auranofin Cevimeline may decrease the excretion rate of Auranofin which could result in a higher serum level. |
Leuprolide Injection | Leuprolide Injection Leuprolide may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Gemfibrozil | Gemfibrozil Cevimeline may decrease the excretion rate of Gemfibrozil which could result in a higher serum level. |
Dipivefrin Ophthalmic | Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Ceftazidime Injection | Ceftazidime Injection Ceftazidime may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Ketoprofen | Ketoprofen Ketoprofen may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Cefotetan Injection | Cefotetan Injection Cefotetan may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Pimozide | Pimozide The metabolism of Cevimeline can be decreased when combined with Pimozide. |
Flurbiprofen | Flurbiprofen Flurbiprofen may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Amiodarone | Amiodarone The metabolism of Cevimeline can be decreased when combined with Amiodarone. |
Aztreonam Injection | Aztreonam Injection Cevimeline may decrease the excretion rate of Aztreonam which could result in a higher serum level. |
Buspirone | Buspirone Cevimeline may decrease the excretion rate of Buspirone which could result in a higher serum level. |
Lovastatin | Lovastatin The metabolism of Cevimeline can be decreased when combined with Lovastatin. |
Ciprofloxacin | Ciprofloxacin Cevimeline may decrease the excretion rate of Ciprofloxacin which could result in a higher serum level. |
Mesalamine | Mesalamine Mesalazine may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Diclofenac | Diclofenac Diclofenac may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Fluoxetine | Fluoxetine The serum concentration of Cevimeline can be increased when it is combined with Fluoxetine. |
Clozapine | Clozapine The metabolism of Clozapine can be decreased when combined with Cevimeline. |
Estazolam | Estazolam Cevimeline may decrease the excretion rate of Estazolam which could result in a higher serum level. |
Idarubicin | Idarubicin The metabolism of Idarubicin can be decreased when combined with Cevimeline. |
Didanosine | Didanosine Cevimeline may decrease the excretion rate of Didanosine which could result in a higher serum level. |
Pentostatin Injection | Pentostatin Injection Cevimeline may decrease the excretion rate of Pentostatin which could result in a higher serum level. |
Etodolac | Etodolac Etodolac may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Felodipine | Felodipine The metabolism of Cevimeline can be decreased when combined with Felodipine. |
Fosinopril | Fosinopril Cevimeline may decrease the excretion rate of Fosinopril which could result in a higher serum level. |
Nabumetone | Nabumetone Nabumetone may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Simvastatin | Simvastatin The metabolism of Simvastatin can be decreased when combined with Cevimeline. |
Lisinopril | Lisinopril Cevimeline may decrease the excretion rate of Lisinopril which could result in a higher serum level. |
Oxaprozin | Oxaprozin Oxaprozin may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Sotalol | Sotalol The metabolism of Sotalol can be decreased when combined with Cevimeline. |
Bisoprolol | Bisoprolol The risk or severity of adverse effects can be increased when Cevimeline is combined with Bisoprolol. |
Zolpidem | Zolpidem The metabolism of Zolpidem can be decreased when combined with Cevimeline. |
Doxazosin | Doxazosin The metabolism of Doxazosin can be decreased when combined with Cevimeline. |
Isradipine | Isradipine Cevimeline may decrease the excretion rate of Isradipine which could result in a higher serum level. |
Omeprazole | Omeprazole The metabolism of Cevimeline can be decreased when combined with Omeprazole. |
Cisapride | Cisapride The metabolism of Cevimeline can be decreased when combined with Cisapride. |
Fluvastatin | Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Cevimeline. |
Venlafaxine | Venlafaxine The metabolism of Venlafaxine can be decreased when combined with Cevimeline. |
Nizatidine | Nizatidine The risk or severity of adverse effects can be increased when Nizatidine is combined with Cevimeline. |
Fluvoxamine | Fluvoxamine The metabolism of Cevimeline can be decreased when combined with Fluvoxamine. |
Nefazodone | Nefazodone Nefazodone may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Lamotrigine | Lamotrigine Cevimeline may decrease the excretion rate of Lamotrigine which could result in a higher serum level. |
Valacyclovir | Valacyclovir Valaciclovir may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Tramadol | Tramadol Cevimeline may decrease the excretion rate of Tramadol which could result in a higher serum level. |
Vinorelbine Injection | Vinorelbine Injection The metabolism of Cevimeline can be decreased when combined with Vinorelbine. |
Carboplatin Injection | Carboplatin Injection Carboplatin may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Lansoprazole | Lansoprazole The metabolism of Cevimeline can be decreased when combined with Lansoprazole. |
Ifosfamide Injection | Ifosfamide Injection Cevimeline may decrease the excretion rate of Ifosfamide which could result in a higher serum level. |
Nicardipine | Nicardipine The metabolism of Cevimeline can be decreased when combined with Nicardipine. |
Bupropion | Bupropion The metabolism of Cevimeline can be decreased when combined with Bupropion. |
Ticlopidine | Ticlopidine The metabolism of Ticlopidine can be decreased when combined with Cevimeline. |
Saquinavir | Saquinavir The metabolism of Cevimeline can be decreased when combined with Saquinavir. |
Metformin | Metformin Cevimeline may decrease the excretion rate of Metformin which could result in a higher serum level. |
Nisoldipine | Nisoldipine Cevimeline may decrease the excretion rate of Nisoldipine which could result in a higher serum level. |
Lamivudine | Lamivudine Cevimeline may decrease the excretion rate of Lamivudine which could result in a higher serum level. |
Acarbose | Acarbose Cevimeline may decrease the excretion rate of Acarbose which could result in a higher serum level. |
Gemcitabine Injection | Gemcitabine Injection Cevimeline may decrease the excretion rate of Gemcitabine which could result in a higher serum level. |
Ritonavir | Ritonavir The serum concentration of Cevimeline can be increased when it is combined with Ritonavir. |
Cidofovir Injection | Cidofovir Injection Cidofovir may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Meropenem Injection | Meropenem Injection Cevimeline may decrease the excretion rate of Meropenem which could result in a higher serum level. |
Clomipramine | Clomipramine The metabolism of Clomipramine can be decreased when combined with Cevimeline. |
Fosfomycin | Fosfomycin Cevimeline may decrease the excretion rate of Fosfomycin which could result in a higher serum level. |
Mirtazapine | Mirtazapine The metabolism of Mirtazapine can be decreased when combined with Cevimeline. |
Topiramate | Topiramate Cevimeline may decrease the excretion rate of Topiramate which could result in a higher serum level. |
Pramipexole | Pramipexole Cevimeline may decrease the excretion rate of Pramipexole which could result in a higher serum level. |
Donepezil | Donepezil The risk or severity of adverse effects can be increased when Cevimeline is combined with Donepezil. |
Nelfinavir | Nelfinavir The metabolism of Nelfinavir can be decreased when combined with Cevimeline. |
Carvedilol | Carvedilol The risk or severity of adverse effects can be increased when Carvedilol is combined with Cevimeline. |
Nilutamide | Nilutamide Cevimeline may decrease the excretion rate of Nilutamide which could result in a higher serum level. |
Flutamide | Flutamide Cevimeline may decrease the excretion rate of Flutamide which could result in a higher serum level. |
Selegiline | Selegiline The metabolism of Cevimeline can be decreased when combined with Selegiline. |
Bicalutamide | Bicalutamide The metabolism of Cevimeline can be decreased when combined with Bicalutamide. |
Sertraline | Sertraline The metabolism of Cevimeline can be decreased when combined with Sertraline. |
Propafenone | Propafenone The metabolism of Cevimeline can be decreased when combined with Propafenone. |
Tamsulosin | Tamsulosin Cevimeline may decrease the excretion rate of Tamsulosin which could result in a higher serum level. |
Quetiapine | Quetiapine Cevimeline may decrease the excretion rate of Quetiapine which could result in a higher serum level. |
Cefepime Injection | Cefepime Injection Cefepime may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Cefprozil | Cefprozil Cefprozil may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Cefpodoxime | Cefpodoxime Cefpodoxime may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Cetirizine | Cetirizine Cevimeline may decrease the excretion rate of Cetirizine which could result in a higher serum level. |
Paroxetine | Paroxetine The metabolism of Cevimeline can be decreased when combined with Paroxetine. |
Tolcapone | Tolcapone Cevimeline may decrease the excretion rate of Tolcapone which could result in a higher serum level. |
Citalopram | Citalopram The metabolism of Cevimeline can be decreased when combined with Citalopram. |
Capecitabine | Capecitabine Cevimeline may decrease the excretion rate of Capecitabine which could result in a higher serum level. |
Abacavir | Abacavir Cevimeline may decrease the excretion rate of Abacavir which could result in a higher serum level. |
Sildenafil | Sildenafil The metabolism of Sildenafil can be decreased when combined with Cevimeline. |
Celecoxib | Celecoxib The metabolism of Cevimeline can be decreased when combined with Celecoxib. |
Rosiglitazone | Rosiglitazone The metabolism of Cevimeline can be decreased when combined with Rosiglitazone. |
Tolterodine | Tolterodine Cevimeline may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Oseltamivir | Oseltamivir Cevimeline may decrease the excretion rate of Oseltamivir which could result in a higher serum level. |
Balsalazide | Balsalazide Balsalazide may decrease the excretion rate of Cevimeline which could result in a higher serum level. |
Nateglinide | Nateglinide Cevimeline may decrease the excretion rate of Nateglinide which could result in a higher serum level. |
Galantamine | Galantamine The metabolism of Galantamine can be decreased when combined with Cevimeline. |
Rabeprazole | Rabeprazole Cevimeline may decrease the excretion rate of Rabeprazole which could result in a higher serum level. |
Terbinafine | Terbinafine The metabolism of Cevimeline can be decreased when combined with Terbinafine. |
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists