Cevimeline

Generic name: Pronounced as (se vim' e leen)
Brand names
  • Evoxac®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 09/15/2016

Cevimeline is used to treat the symptoms of dry mouth in patients with Sjogren's syndrome (a condition that affects the immune system and causes dryness of certain parts of the body such as the eyes and mouth). Cevimeline is in a class of medications called cholinergic agonists. It works by increasing the amount of saliva in the mouth.

Cevimeline comes as a capsule to take by mouth. It is usually taken 3 times a day. Take cevimeline at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cevimeline exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking cevimeline,

  • tell your doctor and pharmacist if you are allergic to cevimeline, or any other medications.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: amiodarone (Pacerone, Cordarone); antifungal medications such as ketoconazole (Nizoral) and itraconazole (Sporanox); beta blockers such as acebutolol (Sectral), atenolol (Tenormin), betaxolol (Kerlone), bisoprolol (Zebeta, in Ziac), carvedilol (Coreg), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), pindolol, propranolol (Inderal), sotalol (Betapace), and timolol (Blocadren); bethanechol (Urecholine); bupropion (Wellbutrin, Wellbutrin XL, Wellbutrin SR, Zyban); calcium channel blockers such as diltiazem (Cardizem, Dilacor, Tiazac, others) and verapamil (Calan, Covera, Isoptin, Verelan); chlorpheniramine (Chlor-Trimeton, Aller-Chlor, Teldrin Allergy, others); cimetidine (Tagamet); clarithromycin (Biaxin); clomipramine (Anafranil); duloxetine (Cymbalta); erythromycin (E.E.S., Erythrocin, E-Mycin); fluoxetine (Prozac, Sarafem); fluvoxamine; haloperidol (Haldol); ipratropium (Atrovent); certain medications for HIV such as indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir); medications for Alzheimer's disease, glaucoma, irritable bowel syndrome, motion sickness, Myastenia Gravis, Parkinson's disease, ulcers, or urinary problems; methadone (Dolophine); nefazodone; paroxetine (Paxil, Paxil CR, Pexeva); quinidine; and troleandomycin. Many other medications may also interact with cevimeline, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor what herbal products you are taking, especially St. John's wort.

  • tell your doctor if you have asthma, acute iritis (uveitis; swelling and irritation inside the eye), or glaucoma (an eye disease). Your doctor may tell you not to take cevimeline.

  • tell your doctor if you have or have ever had chest pain or a heart attack, chronic bronchitis, chronic obstructive pulmonary disease (COPD; a group of lung diseases that includes chronic bronchitis and emphysema), kidney stones, gallstones or heart disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cevimeline, call your doctor.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking cevimeline.

  • you should know cevimeline may cause changes in vision, especially at night or when there is not enough light. Use caution when driving at night or performing hazardous activities in reduced lighting.

  • you should know that cevimeline may cause you to sweat a great deal, which can cause dehydration. Be sure to drink plenty of water and talk to your doctor about ways to prevent dehydration while taking this medication.

Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medication.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Cevimeline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • sweating

    • nausea

    • runny nose

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

    • severe headache

    • changes in vision

    • tearing in eyes

    • excessive sweating

    • difficulty breathing

    • abdominal cramping

    • changes in heartbeat

    • changes in blood pressure

    • confusion

    • shaking hands that you cannot control

  • Cevimeline may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Delavirdine Delavirdine The metabolism of Cevimeline can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Cevimeline can be decreased when combined with Nevirapine.
Dolasetron Dolasetron The metabolism of Dolasetron can be decreased when combined with Cevimeline.
Cilostazol Cilostazol Cevimeline may decrease the excretion rate of Cilostazol which could result in a higher serum level.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Cevimeline may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Fenofibrate Fenofibrate Cevimeline may decrease the excretion rate of Fenofibrate which could result in a higher serum level.
Guanfacine Guanfacine Cevimeline may decrease the excretion rate of Guanfacine which could result in a higher serum level.
Magnesium Hydroxide Magnesium Hydroxide Cevimeline may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Mycophenolate Mycophenolate Cevimeline may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level.
Olsalazine Olsalazine Olsalazine may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Penbutolol Penbutolol The metabolism of Cevimeline can be decreased when combined with Acebutolol.
Potassium Potassium Potassium may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone Prednisone Cevimeline may decrease the excretion rate of Prednisone which could result in a higher serum level.
Ranitidine Ranitidine The metabolism of Ranitidine can be decreased when combined with Cevimeline.
Reserpine Reserpine Cevimeline may decrease the excretion rate of Reserpine which could result in a higher serum level.
Rizatriptan Rizatriptan Cevimeline may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Sumatriptan Sumatriptan Cevimeline may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus Tacrolimus Tacrolimus may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Ampicillin Injection Ampicillin Injection Cevimeline may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection Cevimeline may decrease the excretion rate of Doxycycline which could result in a higher serum level.
Fluconazole Injection Fluconazole Injection Cevimeline may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Foscarnet Injection Foscarnet Injection Foscarnet may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Hydromorphone Injection Hydromorphone Injection Cevimeline may decrease the excretion rate of Hydromorphone which could result in a higher serum level.
Levofloxacin Injection Levofloxacin Injection Cevimeline may decrease the excretion rate of Levofloxacin which could result in a higher serum level.
Meperidine Injection Meperidine Injection Cevimeline may decrease the excretion rate of Meperidine which could result in a higher serum level.
Metoclopramide Injection Metoclopramide Injection The metabolism of Cevimeline can be decreased when combined with Metoclopramide.
Pamidronate Injection Pamidronate Injection Pamidronic acid may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Vancomycin Injection Vancomycin Injection Cevimeline may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Altretamine Altretamine Amphetamine may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Cefuroxime Cefuroxime Cefuroxime may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Cyclosporine Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Cevimeline.
Ondansetron Ondansetron The metabolism of Ondansetron can be decreased when combined with Cevimeline.
Torsemide Torsemide Torasemide may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Olanzapine Olanzapine The metabolism of Olanzapine can be decreased when combined with Cevimeline.
Entacapone Entacapone The metabolism of Cevimeline can be decreased when combined with Entacapone.
Hydroxychloroquine Hydroxychloroquine The metabolism of Cevimeline can be decreased when combined with Hydroxychloroquine.
Meloxicam Meloxicam Meloxicam may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Pantoprazole Pantoprazole Cevimeline may decrease the excretion rate of Pantoprazole which could result in a higher serum level.
Temozolomide Temozolomide Cevimeline may decrease the excretion rate of Temozolomide which could result in a higher serum level.
Zaleplon Zaleplon Cevimeline may decrease the excretion rate of Zaleplon which could result in a higher serum level.
Anakinra Anakinra The metabolism of Cevimeline can be increased when combined with Anakinra.
Rivastigmine Rivastigmine The risk or severity of adverse effects can be increased when Rivastigmine is combined with Cevimeline.
Trimipramine Trimipramine The metabolism of Trimipramine can be decreased when combined with Cevimeline.
Etanercept Injection Etanercept Injection The metabolism of Cevimeline can be increased when combined with Etanercept.
Perindopril Perindopril Cevimeline may decrease the excretion rate of Perindopril which could result in a higher serum level.
Tenofovir Tenofovir Tenofovir may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Eplerenone Eplerenone Eplerenone may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Escitalopram Escitalopram The serum concentration of Cevimeline can be increased when it is combined with Escitalopram.
Zonisamide Zonisamide Cevimeline may increase the excretion rate of Zonisamide which could result in a lower serum level and potentially a reduction in efficacy.
Adalimumab Injection Adalimumab Injection The metabolism of Cevimeline can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Cevimeline.
Atomoxetine Atomoxetine Cevimeline may decrease the excretion rate of Atomoxetine which could result in a higher serum level.
Atazanavir Atazanavir Atazanavir may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Almotriptan Almotriptan Cevimeline may decrease the excretion rate of Almotriptan which could result in a higher serum level.
Eletriptan Eletriptan The metabolism of Eletriptan can be decreased when combined with Cevimeline.
Mefloquine Mefloquine The risk or severity of adverse effects can be increased when Mefloquine is combined with Cevimeline.
Emtricitabine Emtricitabine Cevimeline may decrease the excretion rate of Emtricitabine which could result in a higher serum level.
Memantine Memantine Cevimeline may decrease the excretion rate of Memantine which could result in a higher serum level.
Tegaserod Tegaserod The metabolism of Cevimeline can be decreased when combined with Tegaserod.
Tadalafil Tadalafil Cevimeline may decrease the excretion rate of Tadalafil which could result in a higher serum level.
Progesterone Progesterone The metabolism of Progesterone can be decreased when combined with Cevimeline.
Infliximab Injection Infliximab Injection The metabolism of Cevimeline can be increased when combined with Infliximab.
Protriptyline Protriptyline The metabolism of Protriptyline can be decreased when combined with Cevimeline.
Duloxetine Duloxetine The metabolism of Duloxetine can be decreased when combined with Cevimeline.
Tinidazole Tinidazole Cevimeline may decrease the excretion rate of Tinidazole which could result in a higher serum level.
Trospium Trospium The metabolism of Cevimeline can be decreased when combined with Trospium.
Cefditoren Cefditoren Cevimeline may decrease the excretion rate of Cefdinir which could result in a higher serum level.
Cinacalcet Cinacalcet The metabolism of Cevimeline can be decreased when combined with Cinacalcet.
Cyanocobalamin Injection Cyanocobalamin Injection Cevimeline may decrease the excretion rate of Hydroxocobalamin which could result in a higher serum level.
Erlotinib Erlotinib The metabolism of Erlotinib can be decreased when combined with Cevimeline.
Eszopiclone Eszopiclone Cevimeline may decrease the excretion rate of Eszopiclone which could result in a higher serum level.
Ganciclovir Ganciclovir Cevimeline may decrease the excretion rate of Ganciclovir which could result in a higher serum level.
Ribavirin Ribavirin Cevimeline may decrease the excretion rate of Ribavirin which could result in a higher serum level.
Solifenacin Solifenacin The metabolism of Solifenacin can be decreased when combined with Cevimeline.
Valganciclovir Valganciclovir Cevimeline may decrease the excretion rate of Valganciclovir which could result in a higher serum level.
Adefovir Adefovir Adefovir may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Dextroamphetamine Dextroamphetamine Amphetamine may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The metabolism of Cevimeline can be decreased when combined with Peginterferon alfa-2b.
Ramelteon Ramelteon Cevimeline may decrease the excretion rate of Ramelteon which could result in a higher serum level.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Cevimeline.
Fentanyl Fentanyl Cevimeline may decrease the excretion rate of Fentanyl which could result in a higher serum level.
Pregabalin Pregabalin Cevimeline may decrease the excretion rate of Pregabalin which could result in a higher serum level.
Tipranavir Tipranavir The metabolism of Tipranavir can be decreased when combined with Cevimeline.
Ranolazine Ranolazine The serum concentration of Cevimeline can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Cevimeline can be increased when combined with Abatacept.
Rasagiline Rasagiline Cevimeline may decrease the excretion rate of Rasagiline which could result in a higher serum level.
Imatinib Imatinib The metabolism of Cevimeline can be decreased when combined with Imatinib.
Sitagliptin Sitagliptin Cevimeline may decrease the excretion rate of Sitagliptin which could result in a higher serum level.
Varenicline Varenicline Cevimeline may decrease the excretion rate of Varenicline which could result in a higher serum level.
Gefitinib Gefitinib The metabolism of Cevimeline can be decreased when combined with Gefitinib.
Albuterol Albuterol Cevimeline may decrease the excretion rate of Salbutamol which could result in a higher serum level.
Paliperidone Paliperidone Cevimeline may decrease the excretion rate of Paliperidone which could result in a higher serum level.
Bortezomib Bortezomib The metabolism of Bortezomib can be decreased when combined with Cevimeline.
Clofarabine Injection Clofarabine Injection Cevimeline may decrease the excretion rate of Clofarabine which could result in a higher serum level.
Lubiprostone Lubiprostone Cevimeline may decrease the excretion rate of Lubiprostone which could result in a higher serum level.
Primaquine Primaquine The metabolism of Cevimeline can be decreased when combined with Primaquine.
Pemetrexed Injection Pemetrexed Injection Cevimeline may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Lisdexamfetamine Lisdexamfetamine The metabolism of Cevimeline can be decreased when combined with Lisdexamfetamine.
Sorafenib Sorafenib The metabolism of Sorafenib can be decreased when combined with Cevimeline.
Levocetirizine Levocetirizine Cevimeline may decrease the excretion rate of Levocetirizine which could result in a higher serum level.
Pegaptanib Injection Pegaptanib Injection Cevimeline may decrease the excretion rate of Pegaptanib which could result in a higher serum level.
Mexiletine Mexiletine The metabolism of Mexiletine can be decreased when combined with Cevimeline.
Azacitidine Injection Azacitidine Injection Cevimeline may decrease the excretion rate of Azacitidine which could result in a higher serum level.
Temsirolimus Temsirolimus The metabolism of Cevimeline can be decreased when combined with Temsirolimus.
Lenalidomide Lenalidomide Cevimeline may decrease the excretion rate of Lenalidomide which could result in a higher serum level.
Nilotinib Nilotinib The metabolism of Cevimeline can be decreased when combined with Nilotinib.
Budesonide Budesonide Cevimeline may decrease the excretion rate of Budesonide which could result in a higher serum level.
Desmopressin Desmopressin Desmopressin may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Betaine Betaine The risk or severity of adverse effects can be increased when Glycine betaine is combined with Cevimeline.
Doripenem Injection Doripenem Injection Cevimeline may decrease the excretion rate of Doripenem which could result in a higher serum level.
Arsenic Trioxide Injection Arsenic Trioxide Injection Cevimeline may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level.
Desvenlafaxine Desvenlafaxine Cevimeline may decrease the excretion rate of Desvenlafaxine which could result in a higher serum level.
Nebivolol Nebivolol The risk or severity of adverse effects can be increased when Nebivolol is combined with Cevimeline.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Cevimeline.
Certolizumab Injection Certolizumab Injection The metabolism of Certolizumab pegol can be increased when combined with Cevimeline.
Daptomycin Injection Daptomycin Injection Daptomycin may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Methylnaltrexone Injection Methylnaltrexone Injection Cevimeline may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
Midazolam Midazolam Cevimeline may decrease the excretion rate of Midazolam which could result in a higher serum level.
Dexrazoxane Injection Dexrazoxane Injection Cevimeline may decrease the excretion rate of Dexrazoxane which could result in a higher serum level.
Milnacipran Milnacipran Cevimeline may decrease the excretion rate of Milnacipran which could result in a higher serum level.
Plerixafor Injection Plerixafor Injection Cevimeline may decrease the excretion rate of Plerixafor which could result in a higher serum level.
Fesoterodine Fesoterodine Cevimeline may decrease the excretion rate of Fesoterodine which could result in a higher serum level.
Betaxolol Betaxolol The risk or severity of adverse effects can be increased when Betaxolol is combined with Cevimeline.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Cevimeline.
Prasugrel Prasugrel Cevimeline may decrease the excretion rate of Prasugrel which could result in a higher serum level.
Everolimus Everolimus The metabolism of Cevimeline can be decreased when combined with Everolimus.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) Tolvaptan may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Dronedarone Dronedarone The metabolism of Dronedarone can be decreased when combined with Cevimeline.
Pralatrexate Injection Pralatrexate Injection Cevimeline may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection Cevimeline may decrease the excretion rate of Palonosetron which could result in a higher serum level.
Saxagliptin Saxagliptin Cevimeline may decrease the excretion rate of Saxagliptin which could result in a higher serum level.
Telavancin Injection Telavancin Injection Cevimeline may decrease the excretion rate of Telavancin which could result in a higher serum level.
Tapentadol Tapentadol The metabolism of Cevimeline can be decreased when combined with Tapentadol.
Topotecan Topotecan Cevimeline may decrease the excretion rate of Topotecan which could result in a higher serum level.
Golimumab Injection Golimumab Injection The metabolism of Cevimeline can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Cevimeline can be decreased when combined with Pazopanib.
Oxymorphone Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Cevimeline.
Tocilizumab Injection Tocilizumab Injection The metabolism of Cevimeline can be increased when combined with Tocilizumab.
Dalfampridine Dalfampridine Cevimeline may decrease the excretion rate of Dalfampridine which could result in a higher serum level.
Ceftaroline Injection Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Acetaminophen Injection Acetaminophen Injection Cevimeline may decrease the excretion rate of Acetaminophen which could result in a higher serum level.
Vilazodone Vilazodone The metabolism of Cevimeline can be decreased when combined with Vilazodone.
Ipilimumab Injection Ipilimumab Injection Cevimeline may decrease the excretion rate of Ipilimumab which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection Aldesleukin may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Terbutaline Injection Terbutaline Injection Cevimeline may decrease the excretion rate of Terbutaline which could result in a higher serum level.
Roflumilast Roflumilast Cevimeline may decrease the excretion rate of Roflumilast which could result in a higher serum level.
Rilpivirine Rilpivirine The metabolism of Cevimeline can be decreased when combined with Rilpivirine.
Abiraterone Abiraterone The metabolism of Cevimeline can be decreased when combined with Abiraterone.
Rivaroxaban Rivaroxaban Cevimeline may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Ruxolitinib Ruxolitinib Cevimeline may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Clobazam Clobazam The metabolism of Clobazam can be decreased when combined with Cevimeline.
Vemurafenib Vemurafenib The metabolism of Cevimeline can be decreased when combined with Vemurafenib.
Deferiprone Deferiprone Cevimeline may decrease the excretion rate of Deferiprone which could result in a higher serum level.
Naloxone Injection Naloxone Injection Cevimeline may decrease the excretion rate of Naloxone which could result in a higher serum level.
Fondaparinux Injection Fondaparinux Injection Cevimeline may decrease the excretion rate of Fondaparinux which could result in a higher serum level.
Enzalutamide Enzalutamide Cevimeline may decrease the excretion rate of Enzalutamide which could result in a higher serum level.
Mirabegron Mirabegron The metabolism of Mirabegron can be decreased when combined with Cevimeline.
Teduglutide Injection Teduglutide Injection Cevimeline may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Alogliptin Alogliptin Cevimeline may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Ponatinib Ponatinib The metabolism of Ponatinib can be decreased when combined with Cevimeline.
Pomalidomide Pomalidomide Cevimeline may decrease the excretion rate of Pomalidomide which could result in a higher serum level.
Canagliflozin Canagliflozin Cevimeline may increase the excretion rate of Canagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Methazolamide Methazolamide Methazolamide may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Ospemifene Ospemifene The metabolism of Cevimeline can be decreased when combined with Ospemifene.
Trametinib Trametinib Cevimeline may decrease the excretion rate of Trametinib which could result in a higher serum level.
Levomilnacipran Levomilnacipran Cevimeline may decrease the excretion rate of Levomilnacipran which could result in a higher serum level.
Ertapenem Injection Ertapenem Injection Cevimeline may decrease the excretion rate of Ertapenem which could result in a higher serum level.
Vortioxetine Vortioxetine Cevimeline may decrease the excretion rate of Vortioxetine which could result in a higher serum level.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Cevimeline.
Ketorolac Injection Ketorolac Injection Ketorolac may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Sofosbuvir Sofosbuvir Cevimeline may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin Dapagliflozin may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Apremilast Apremilast The metabolism of Apremilast can be increased when combined with Cevimeline.
Droxidopa Droxidopa Cevimeline may decrease the excretion rate of Droxidopa which could result in a higher serum level.
Siltuximab Injection Siltuximab Injection The metabolism of Cevimeline can be increased when combined with Siltuximab.
Testosterone Injection Testosterone Injection Cevimeline may decrease the excretion rate of Testosterone which could result in a higher serum level.
Oritavancin Injection Oritavancin Injection The metabolism of Cevimeline can be decreased when combined with Oritavancin.
Edoxaban Edoxaban Cevimeline may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Methamphetamine Methamphetamine Cevimeline may decrease the excretion rate of Metamfetamine which could result in a higher serum level.
Tasimelteon Tasimelteon Cevimeline may decrease the excretion rate of Tasimelteon which could result in a higher serum level.
Secukinumab Injection Secukinumab Injection The metabolism of Cevimeline can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The metabolism of Risperidone can be decreased when combined with Cevimeline.
Lenvatinib Lenvatinib The metabolism of Cevimeline can be decreased when combined with Lenvatinib.
Naloxegol Naloxegol The metabolism of Cevimeline can be decreased when combined with Naloxegol.
Panobinostat Panobinostat The metabolism of Cevimeline can be decreased when combined with Panobinostat.
Haloperidol Injection Haloperidol Injection The serum concentration of Cevimeline can be increased when it is combined with Haloperidol.
Amiloride Amiloride Amiloride may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Macitentan Macitentan Cevimeline may decrease the excretion rate of Macitentan which could result in a higher serum level.
Rolapitant Rolapitant The metabolism of Cevimeline can be decreased when combined with Rolapitant.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Cevimeline.
Cariprazine Cariprazine The metabolism of Cariprazine can be decreased when combined with Cevimeline.
Penicillin G Procaine Injection Penicillin G Procaine Injection Cevimeline may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Cevimeline.
Ixazomib Ixazomib Cevimeline may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lesinurad Lesinurad Cevimeline may decrease the excretion rate of Lesinurad which could result in a higher serum level.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Brivaracetam Injection Brivaracetam Injection Cevimeline may decrease the excretion rate of Brivaracetam which could result in a higher serum level.
Cobicistat Cobicistat The metabolism of Cevimeline can be decreased when combined with Cobicistat.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Cevimeline can be decreased when combined with Diphenhydramine.
Furosemide Injection Furosemide Injection Cevimeline may increase the excretion rate of Furosemide which could result in a lower serum level and potentially a reduction in efficacy.
Rucaparib Rucaparib The metabolism of Cevimeline can be decreased when combined with Rucaparib.
Lixisenatide Injection Lixisenatide Injection Cevimeline may decrease the excretion rate of Lixisenatide which could result in a higher serum level.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Cevimeline can be decreased when combined with Doxepin.
Deutetrabenazine Deutetrabenazine Cevimeline may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level.
Valbenazine Valbenazine Cevimeline may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Safinamide Safinamide The metabolism of Cevimeline can be decreased when combined with Safinamide.
Naldemedine Naldemedine Cevimeline may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Midostaurin Midostaurin The metabolism of Cevimeline can be decreased when combined with Midostaurin.
Enasidenib Enasidenib The metabolism of Cevimeline can be decreased when combined with Enasidenib.
Benznidazole Benznidazole Cevimeline may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Delafloxacin Delafloxacin Cevimeline may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Letermovir Letermovir The metabolism of Letermovir can be decreased when combined with Cevimeline.
Tetrabenazine Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Cevimeline.
Ertugliflozin Ertugliflozin Ertugliflozin may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Buprenorphine Injection Buprenorphine Injection The metabolism of Cevimeline can be decreased when combined with Buprenorphine.
Apalutamide Apalutamide Cevimeline may decrease the excretion rate of Apalutamide which could result in a higher serum level.
Baricitinib Baricitinib Cevimeline may decrease the excretion rate of Baricitinib which could result in a higher serum level.
Lofexidine Lofexidine Cevimeline may decrease the excretion rate of Lofexidine which could result in a higher serum level.
Plazomicin Injection Plazomicin Injection Cevimeline may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Eliglustat Eliglustat The metabolism of Cevimeline can be decreased when combined with Eliglustat.
Encorafenib Encorafenib The metabolism of Encorafenib can be decreased when combined with Cevimeline.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Cevimeline.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Cevimeline.
Cannabidiol Cannabidiol The metabolism of Cannabidiol can be decreased when combined with Cevimeline.
Dacomitinib Dacomitinib The metabolism of Cevimeline can be decreased when combined with Dacomitinib.
Stiripentol Stiripentol The metabolism of Cevimeline can be decreased when combined with Stiripentol.
Rifamycin Rifamycin The metabolism of Cevimeline can be decreased when combined with Rifamycin.
Prucalopride Prucalopride Cevimeline may decrease the excretion rate of Prucalopride which could result in a higher serum level.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Cevimeline can be increased when combined with Emapalumab.
Acyclovir Ophthalmic Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Solriamfetol Solriamfetol Cevimeline may decrease the excretion rate of Solriamfetol which could result in a higher serum level.
Triclabendazole Triclabendazole The metabolism of Cevimeline can be decreased when combined with Triclabendazole.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Cevimeline.
Pitolisant Pitolisant The serum concentration of Cevimeline can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The metabolism of Cevimeline can be decreased when combined with Fedratinib.
Phenytoin Injection Phenytoin Injection The metabolism of Phenytoin can be decreased when combined with Cevimeline.
Cenobamate Cenobamate The serum concentration of Cevimeline can be decreased when it is combined with Cenobamate.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Cevimeline.
Fenfluramine Fenfluramine The metabolism of Cevimeline can be decreased when combined with Fenfluramine.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Cevimeline can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives Drospirenone may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Viloxazine Viloxazine Cevimeline may decrease the excretion rate of Viloxazine which could result in a higher serum level.
Tobramycin Injection Tobramycin Injection Tobramycin may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Theophylline Theophylline The metabolism of Theophylline can be decreased when combined with Cevimeline.
Fenoprofen Fenoprofen Fenoprofen may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Indomethacin Indomethacin Indomethacin may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Mefenamic Acid Mefenamic Acid Mefenamic acid may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Naproxen Naproxen Naproxen may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Tolmetin Tolmetin Tolmetin may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Sulindac Sulindac Sulindac may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Trazodone Trazodone The metabolism of Cevimeline can be decreased when combined with Trazodone.
Isotretinoin Isotretinoin Cevimeline may decrease the excretion rate of Isotretinoin which could result in a higher serum level.
Sucralfate Sucralfate Cevimeline may decrease the excretion rate of Sucralfate which could result in a higher serum level.
Hydroxyurea Hydroxyurea The metabolism of Cevimeline can be decreased when combined with Hydroxyurea.
Floxuridine Floxuridine Cevimeline may decrease the excretion rate of Floxuridine which could result in a higher serum level.
Metaxalone Metaxalone Cevimeline may decrease the excretion rate of Metaxalone which could result in a higher serum level.
Methotrexate Injection Methotrexate Injection Methotrexate may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Chlorpromazine Chlorpromazine The metabolism of Chlorpromazine can be decreased when combined with Cevimeline.
Diazepam Diazepam Cevimeline may decrease the excretion rate of Diazepam which could result in a higher serum level.
Oxazepam Oxazepam Cevimeline may decrease the excretion rate of Oxazepam which could result in a higher serum level.
Flurazepam Flurazepam Cevimeline may decrease the excretion rate of Flurazepam which could result in a higher serum level.
Clorazepate Clorazepate Cevimeline may decrease the excretion rate of Clorazepic acid which could result in a higher serum level.
Lorazepam Lorazepam Cevimeline may decrease the excretion rate of Lorazepam which could result in a higher serum level.
Carmustine Carmustine Cevimeline may decrease the excretion rate of Carmustine which could result in a higher serum level.
Amantadine Amantadine Cevimeline may decrease the excretion rate of Amantadine which could result in a higher serum level.
Codeine Codeine Cevimeline may decrease the excretion rate of Codeine which could result in a higher serum level.
Tranylcypromine Tranylcypromine The metabolism of Cevimeline can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Phenelzine can be decreased when combined with Cevimeline.
Tetracycline Tetracycline Cevimeline may decrease the excretion rate of Tetracycline which could result in a higher serum level.
Prochlorperazine Prochlorperazine The metabolism of Prochlorperazine can be decreased when combined with Cevimeline.
Thioridazine Thioridazine The metabolism of Cevimeline can be decreased when combined with Thioridazine.
Bleomycin Bleomycin Cevimeline may decrease the excretion rate of Bleomycin which could result in a higher serum level.
Sulfadiazine Sulfadiazine Cevimeline may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Oxycodone Oxycodone The metabolism of Oxycodone can be decreased when combined with Cevimeline.
Methadone Methadone The metabolism of Cevimeline can be decreased when combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Cevimeline can be decreased when combined with Oxybutynin.
Benztropine Benztropine Cevimeline may decrease the excretion rate of Benzatropine which could result in a higher serum level.
Maprotiline Maprotiline Cevimeline may decrease the excretion rate of Maprotiline which could result in a higher serum level.
Ibuprofen Ibuprofen Ibuprofen may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Orphenadrine Orphenadrine The metabolism of Cevimeline can be decreased when combined with Orphenadrine.
Perphenazine Perphenazine The metabolism of Cevimeline can be decreased when combined with Perphenazine.
Azathioprine Azathioprine Cevimeline may decrease the excretion rate of Azathioprine which could result in a higher serum level.
Fluphenazine Fluphenazine The metabolism of Cevimeline can be decreased when combined with Fluphenazine.
Methylphenidate Methylphenidate Cevimeline may decrease the excretion rate of Methylphenidate which could result in a higher serum level.
Amoxapine Amoxapine The metabolism of Cevimeline can be decreased when combined with Amoxapine.
Sulfasalazine Sulfasalazine Sulfasalazine may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Doxorubicin Doxorubicin The metabolism of Cevimeline can be decreased when combined with Doxorubicin.
Mechlorethamine Mechlorethamine The risk or severity of adverse effects can be increased when Mechlorethamine is combined with Cevimeline.
Pyridostigmine Pyridostigmine The risk or severity of adverse effects can be increased when Pyridostigmine is combined with Cevimeline.
Phenazopyridine Phenazopyridine Phenazopyridine may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Carbamazepine Carbamazepine Cevimeline may decrease the excretion rate of Carbamazepine which could result in a higher serum level.
Methyldopa Methyldopa Cevimeline may decrease the excretion rate of Methyldopa which could result in a higher serum level.
Clonidine Clonidine The metabolism of Clonidine can be decreased when combined with Cevimeline.
Hydralazine Hydralazine Cevimeline may decrease the excretion rate of Hydralazine which could result in a higher serum level.
Cimetidine Cimetidine The metabolism of Cimetidine can be decreased when combined with Cevimeline.
Gentamicin Injection Gentamicin Injection Gentamicin may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Warfarin Warfarin Cevimeline may decrease the excretion rate of Warfarin which could result in a higher serum level.
Clonazepam Clonazepam Cevimeline may decrease the excretion rate of Clonazepam which could result in a higher serum level.
Loperamide Loperamide The metabolism of Loperamide can be decreased when combined with Cevimeline.
Promethazine Promethazine The metabolism of Cevimeline can be decreased when combined with Promethazine.
Meclofenamate Meclofenamate Meclofenamic acid may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Cevimeline may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Digoxin Digoxin Cevimeline may decrease the excretion rate of Digoxin which could result in a higher serum level.
Chloroquine Chloroquine The metabolism of Chloroquine can be decreased when combined with Cevimeline.
Quinine Quinine The metabolism of Cevimeline can be decreased when combined with Quinine.
Triamterene Triamterene Triamterene may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Chlorothiazide Chlorothiazide Chlorothiazide may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Chlorthalidone Chlorthalidone Chlorthalidone may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Metolazone Metolazone Cevimeline may increase the excretion rate of Metolazone which could result in a lower serum level and potentially a reduction in efficacy.
Isosorbide Isosorbide Isosorbide may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Secobarbital Secobarbital Cevimeline may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Cevimeline.
Amitriptyline Amitriptyline The metabolism of Cevimeline can be decreased when combined with Amitriptyline.
Imipramine Imipramine The metabolism of Imipramine can be decreased when combined with Cevimeline.
Probenecid Probenecid Cevimeline may decrease the excretion rate of Probenecid which could result in a higher serum level.
Quinidine Quinidine The metabolism of Cevimeline can be decreased when combined with Quinidine.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Cevimeline.
Isoniazid Isoniazid Cevimeline may decrease the excretion rate of Isoniazid which could result in a higher serum level.
Pyrazinamide Pyrazinamide Cevimeline may decrease the excretion rate of Pyrazinamide which could result in a higher serum level.
Disopyramide Disopyramide Cevimeline may decrease the excretion rate of Disopyramide which could result in a higher serum level.
Tamoxifen Tamoxifen The metabolism of Cevimeline can be decreased when combined with Tamoxifen.
Butabarbital Butabarbital Cevimeline may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Liothyronine Liothyronine Cevimeline may decrease the excretion rate of Liothyronine which could result in a higher serum level.
Methimazole Methimazole The metabolism of Cevimeline can be decreased when combined with Methimazole.
Chlorpropamide Chlorpropamide Cevimeline may decrease the excretion rate of Chlorpropamide which could result in a higher serum level.
Tolbutamide Tolbutamide Cevimeline may decrease the excretion rate of Tolbutamide which could result in a higher serum level.
Tolazamide Tolazamide Cevimeline may decrease the excretion rate of Tolazamide which could result in a higher serum level.
Dextromethorphan Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Cevimeline.
Niacin Niacin The metabolism of Cevimeline can be decreased when combined with Niacin.
Baclofen Baclofen Baclofen may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Clemastine Clemastine The metabolism of Cevimeline can be decreased when combined with Clemastine.
Chlorpheniramine Chlorpheniramine The metabolism of Cevimeline can be decreased when combined with Chlorpheniramine.
Meclizine Meclizine The metabolism of Meclizine can be decreased when combined with Cevimeline.
Ethambutol Ethambutol Cevimeline may decrease the excretion rate of Ethambutol which could result in a higher serum level.
Methyclothiazide Methyclothiazide Methyclothiazide may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Hydrochlorothiazide Hydrochlorothiazide Hydrochlorothiazide may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Chlorzoxazone Chlorzoxazone Cevimeline may decrease the excretion rate of Chlorzoxazone which could result in a higher serum level.
Pyridoxine Pyridoxine Pyridoxine may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Folic Acid Folic Acid Folic acid may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The risk or severity of adverse effects can be increased when Cevimeline is combined with Propranolol.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Cevimeline.
Spironolactone Spironolactone Spironolactone may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Amphotericin B Injection Amphotericin B Injection Amphotericin B may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Phytonadione Phytonadione Cevimeline may decrease the excretion rate of Phylloquinone which could result in a higher serum level.
Amikacin Injection Amikacin Injection Amikacin may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Nadolol Nadolol The risk or severity of adverse effects can be increased when Cevimeline is combined with Nadolol.
Allopurinol Allopurinol Cevimeline may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Flavoxate Flavoxate Cevimeline may decrease the excretion rate of Flavoxate which could result in a higher serum level.
Colchicine Colchicine Cevimeline may decrease the excretion rate of Colchicine which could result in a higher serum level.
Cefaclor Cefaclor Cefaclor may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Cefadroxil Cefadroxil Cefadroxil may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection Cefazolin may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Cephalexin Cephalexin Cephalexin may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Cefoxitin Injection Cefoxitin Injection Cefoxitin may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Dacarbazine Dacarbazine Cevimeline may decrease the excretion rate of Dacarbazine which could result in a higher serum level.
Acetazolamide Acetazolamide Acetazolamide may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Cefotaxime Injection Cefotaxime Injection Cefotaxime may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Calcitonin Salmon Injection Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Ketoconazole Ketoconazole The metabolism of Cevimeline can be decreased when combined with Ketoconazole.
Pyrantel Pyrantel Cevimeline may decrease the excretion rate of Pyrantel which could result in a higher serum level.
Thiotepa Injection Thiotepa Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Cevimeline.
Vinblastine Vinblastine The metabolism of Cevimeline can be decreased when combined with Vinblastine.
Ethacrynic Acid Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Colistimethate Injection Colistimethate Injection Colistimethate may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Metoprolol Metoprolol The metabolism of Metoprolol can be decreased when combined with Cevimeline.
Hydroxyzine Hydroxyzine The metabolism of Cevimeline can be decreased when combined with Hydroxyzine.
Aspirin Aspirin Acetylsalicylic acid may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Salsalate Salsalate Salsalate may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Alprazolam Alprazolam Cevimeline may decrease the excretion rate of Alprazolam which could result in a higher serum level.
Temazepam Temazepam Cevimeline may decrease the excretion rate of Temazepam which could result in a higher serum level.
Triazolam Triazolam Cevimeline may decrease the excretion rate of Triazolam which could result in a higher serum level.
Dicyclomine Dicyclomine Cevimeline may decrease the excretion rate of Dicyclomine which could result in a higher serum level.
Propantheline Propantheline Cevimeline may decrease the excretion rate of Propantheline which could result in a higher serum level.
Trimethoprim Trimethoprim Cevimeline may decrease the excretion rate of Trimethoprim which could result in a higher serum level.
Diltiazem Diltiazem The metabolism of Diltiazem can be decreased when combined with Cevimeline.
Nifedipine Nifedipine The metabolism of Nifedipine can be decreased when combined with Cevimeline.
Timolol Timolol The risk or severity of adverse effects can be increased when Cevimeline is combined with Timolol.
Verapamil Verapamil The metabolism of Verapamil can be decreased when combined with Cevimeline.
Atenolol Atenolol The risk or severity of adverse effects can be increased when Atenolol is combined with Cevimeline.
Pindolol Pindolol The risk or severity of adverse effects can be increased when Cevimeline is combined with Pindolol.
Cisplatin Injection Cisplatin Injection Cevimeline may decrease the excretion rate of Cisplatin which could result in a higher serum level.
Diflunisal Diflunisal Diflunisal may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Piroxicam Piroxicam Piroxicam may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Bumetanide Bumetanide Cevimeline may increase the excretion rate of Bumetanide which could result in a lower serum level and potentially a reduction in efficacy.
Glipizide Glipizide Cevimeline may decrease the excretion rate of Glipizide which could result in a higher serum level.
Indapamide Indapamide Cevimeline may increase the excretion rate of Indapamide which could result in a lower serum level and potentially a reduction in efficacy.
Amoxicillin Amoxicillin Cevimeline may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
Oxacillin Injection Oxacillin Injection Cevimeline may decrease the excretion rate of Oxacillin which could result in a higher serum level.
Pentoxifylline Pentoxifylline Cevimeline may decrease the excretion rate of Pentoxifylline which could result in a higher serum level.
Pentamidine Injection Pentamidine Injection Pentamidine may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Ceftriaxone Injection Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Labetalol Labetalol The metabolism of Cevimeline can be decreased when combined with Labetalol.
Auranofin Auranofin Cevimeline may decrease the excretion rate of Auranofin which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection Leuprolide may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Gemfibrozil Gemfibrozil Cevimeline may decrease the excretion rate of Gemfibrozil which could result in a higher serum level.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Ceftazidime Injection Ceftazidime Injection Ceftazidime may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Ketoprofen Ketoprofen Ketoprofen may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Cefotetan Injection Cefotetan Injection Cefotetan may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Pimozide Pimozide The metabolism of Cevimeline can be decreased when combined with Pimozide.
Flurbiprofen Flurbiprofen Flurbiprofen may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Amiodarone Amiodarone The metabolism of Cevimeline can be decreased when combined with Amiodarone.
Aztreonam Injection Aztreonam Injection Cevimeline may decrease the excretion rate of Aztreonam which could result in a higher serum level.
Buspirone Buspirone Cevimeline may decrease the excretion rate of Buspirone which could result in a higher serum level.
Lovastatin Lovastatin The metabolism of Cevimeline can be decreased when combined with Lovastatin.
Ciprofloxacin Ciprofloxacin Cevimeline may decrease the excretion rate of Ciprofloxacin which could result in a higher serum level.
Mesalamine Mesalamine Mesalazine may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Diclofenac Diclofenac Diclofenac may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Fluoxetine Fluoxetine The serum concentration of Cevimeline can be increased when it is combined with Fluoxetine.
Clozapine Clozapine The metabolism of Clozapine can be decreased when combined with Cevimeline.
Estazolam Estazolam Cevimeline may decrease the excretion rate of Estazolam which could result in a higher serum level.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Cevimeline.
Didanosine Didanosine Cevimeline may decrease the excretion rate of Didanosine which could result in a higher serum level.
Pentostatin Injection Pentostatin Injection Cevimeline may decrease the excretion rate of Pentostatin which could result in a higher serum level.
Etodolac Etodolac Etodolac may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Felodipine Felodipine The metabolism of Cevimeline can be decreased when combined with Felodipine.
Fosinopril Fosinopril Cevimeline may decrease the excretion rate of Fosinopril which could result in a higher serum level.
Nabumetone Nabumetone Nabumetone may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Simvastatin Simvastatin The metabolism of Simvastatin can be decreased when combined with Cevimeline.
Lisinopril Lisinopril Cevimeline may decrease the excretion rate of Lisinopril which could result in a higher serum level.
Oxaprozin Oxaprozin Oxaprozin may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Cevimeline.
Bisoprolol Bisoprolol The risk or severity of adverse effects can be increased when Cevimeline is combined with Bisoprolol.
Zolpidem Zolpidem The metabolism of Zolpidem can be decreased when combined with Cevimeline.
Doxazosin Doxazosin The metabolism of Doxazosin can be decreased when combined with Cevimeline.
Isradipine Isradipine Cevimeline may decrease the excretion rate of Isradipine which could result in a higher serum level.
Omeprazole Omeprazole The metabolism of Cevimeline can be decreased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Cevimeline can be decreased when combined with Cisapride.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Cevimeline.
Venlafaxine Venlafaxine The metabolism of Venlafaxine can be decreased when combined with Cevimeline.
Nizatidine Nizatidine The risk or severity of adverse effects can be increased when Nizatidine is combined with Cevimeline.
Fluvoxamine Fluvoxamine The metabolism of Cevimeline can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone Nefazodone may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Lamotrigine Lamotrigine Cevimeline may decrease the excretion rate of Lamotrigine which could result in a higher serum level.
Valacyclovir Valacyclovir Valaciclovir may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Tramadol Tramadol Cevimeline may decrease the excretion rate of Tramadol which could result in a higher serum level.
Vinorelbine Injection Vinorelbine Injection The metabolism of Cevimeline can be decreased when combined with Vinorelbine.
Carboplatin Injection Carboplatin Injection Carboplatin may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Lansoprazole Lansoprazole The metabolism of Cevimeline can be decreased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection Cevimeline may decrease the excretion rate of Ifosfamide which could result in a higher serum level.
Nicardipine Nicardipine The metabolism of Cevimeline can be decreased when combined with Nicardipine.
Bupropion Bupropion The metabolism of Cevimeline can be decreased when combined with Bupropion.
Ticlopidine Ticlopidine The metabolism of Ticlopidine can be decreased when combined with Cevimeline.
Saquinavir Saquinavir The metabolism of Cevimeline can be decreased when combined with Saquinavir.
Metformin Metformin Cevimeline may decrease the excretion rate of Metformin which could result in a higher serum level.
Nisoldipine Nisoldipine Cevimeline may decrease the excretion rate of Nisoldipine which could result in a higher serum level.
Lamivudine Lamivudine Cevimeline may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Acarbose Acarbose Cevimeline may decrease the excretion rate of Acarbose which could result in a higher serum level.
Gemcitabine Injection Gemcitabine Injection Cevimeline may decrease the excretion rate of Gemcitabine which could result in a higher serum level.
Ritonavir Ritonavir The serum concentration of Cevimeline can be increased when it is combined with Ritonavir.
Cidofovir Injection Cidofovir Injection Cidofovir may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Meropenem Injection Meropenem Injection Cevimeline may decrease the excretion rate of Meropenem which could result in a higher serum level.
Clomipramine Clomipramine The metabolism of Clomipramine can be decreased when combined with Cevimeline.
Fosfomycin Fosfomycin Cevimeline may decrease the excretion rate of Fosfomycin which could result in a higher serum level.
Mirtazapine Mirtazapine The metabolism of Mirtazapine can be decreased when combined with Cevimeline.
Topiramate Topiramate Cevimeline may decrease the excretion rate of Topiramate which could result in a higher serum level.
Pramipexole Pramipexole Cevimeline may decrease the excretion rate of Pramipexole which could result in a higher serum level.
Donepezil Donepezil The risk or severity of adverse effects can be increased when Cevimeline is combined with Donepezil.
Nelfinavir Nelfinavir The metabolism of Nelfinavir can be decreased when combined with Cevimeline.
Carvedilol Carvedilol The risk or severity of adverse effects can be increased when Carvedilol is combined with Cevimeline.
Nilutamide Nilutamide Cevimeline may decrease the excretion rate of Nilutamide which could result in a higher serum level.
Flutamide Flutamide Cevimeline may decrease the excretion rate of Flutamide which could result in a higher serum level.
Selegiline Selegiline The metabolism of Cevimeline can be decreased when combined with Selegiline.
Bicalutamide Bicalutamide The metabolism of Cevimeline can be decreased when combined with Bicalutamide.
Sertraline Sertraline The metabolism of Cevimeline can be decreased when combined with Sertraline.
Propafenone Propafenone The metabolism of Cevimeline can be decreased when combined with Propafenone.
Tamsulosin Tamsulosin Cevimeline may decrease the excretion rate of Tamsulosin which could result in a higher serum level.
Quetiapine Quetiapine Cevimeline may decrease the excretion rate of Quetiapine which could result in a higher serum level.
Cefepime Injection Cefepime Injection Cefepime may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Cefprozil Cefprozil Cefprozil may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Cefpodoxime Cefpodoxime Cefpodoxime may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Cetirizine Cetirizine Cevimeline may decrease the excretion rate of Cetirizine which could result in a higher serum level.
Paroxetine Paroxetine The metabolism of Cevimeline can be decreased when combined with Paroxetine.
Tolcapone Tolcapone Cevimeline may decrease the excretion rate of Tolcapone which could result in a higher serum level.
Citalopram Citalopram The metabolism of Cevimeline can be decreased when combined with Citalopram.
Capecitabine Capecitabine Cevimeline may decrease the excretion rate of Capecitabine which could result in a higher serum level.
Abacavir Abacavir Cevimeline may decrease the excretion rate of Abacavir which could result in a higher serum level.
Sildenafil Sildenafil The metabolism of Sildenafil can be decreased when combined with Cevimeline.
Celecoxib Celecoxib The metabolism of Cevimeline can be decreased when combined with Celecoxib.
Rosiglitazone Rosiglitazone The metabolism of Cevimeline can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine Cevimeline may decrease the excretion rate of Tolterodine which could result in a higher serum level.
Oseltamivir Oseltamivir Cevimeline may decrease the excretion rate of Oseltamivir which could result in a higher serum level.
Balsalazide Balsalazide Balsalazide may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Nateglinide Nateglinide Cevimeline may decrease the excretion rate of Nateglinide which could result in a higher serum level.
Galantamine Galantamine The metabolism of Galantamine can be decreased when combined with Cevimeline.
Rabeprazole Rabeprazole Cevimeline may decrease the excretion rate of Rabeprazole which could result in a higher serum level.
Terbinafine Terbinafine The metabolism of Cevimeline can be decreased when combined with Terbinafine.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists