FDA-filed SPL labeling · retrieved through openFDA

Flavoxate

Flavoxate is a urinary tract antispasmodic used to relieve symptoms such as painful urination, urgency, frequency, and incontinence caused by bladder and urinary tract conditions.

Brand name Urispas
Drug class Cholinergic Muscarinic Antagonists
Rx Form 1 Route Oral
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 3 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

At a glance
Linked label effectiveMay 31, 2023
Clinical labels in scope 3
AvailabilityRx
Earliest approval/marketing year 1970
FDA-listed product records 8
Boxed warningNone found in compared labels
How we combine label and product data →
No current FDA shortage listed · checked Sep 17, 2026
Flavoxate at a glance The quick version — the full detail is in the Patient Information Guide below.
💊
HelloPharmacist Editorial Team Bottom Line
Flavoxate Hydrochloride is a short-term symptom reliever for the discomfort of urinary tract conditions — it eases urgency, pain, and frequency but does not treat infection on its own. It's most effective when paired with appropriate antibiotic therapy prescribed by your doctor. Use it as directed, and reach out to your prescriber if you notice eye pain, confusion, or any allergic reaction.

📖 Flavoxate: Patient Information Guide

A plain-language walkthrough of Flavoxate — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.

🎯What it's used for

Flavoxate is used to relieve uncomfortable urinary symptoms caused by inflammation or infection of the urinary tract. It treats symptoms — not the underlying infection itself — and is meant to be used alongside antibiotics or other appropriate treatments.

  • Painful or burning urination (dysuria)
  • Sudden, strong urge to urinate (urgency)
  • Needing to urinate more often than normal (frequency)
  • Waking up at night to urinate (nocturia)
  • Lower abdominal or pelvic pain (suprapubic pain)
  • Bladder leakage (incontinence)
  • These symptoms may be caused by cystitis, prostatitis, urethritis, urethrocystitis, or urethrotrigonitis
⚙️How it works

Flavoxate works by directly relaxing the smooth muscle in the walls of the urinary tract. When the urinary tract is irritated or infected, the muscles can go into spasm — causing that urgent, frequent, painful need to urinate. Flavoxate calms those spasms, easing the discomfort. It does not fight bacteria or treat infection; it simply helps the muscle relax while other treatments address the root cause.

💊How it's taken

Flavoxate Hydrochloride is taken as an oral tablet, several times throughout the day. It is approved for adults and children over 12 years of age; it is not recommended for children 12 and under. Your doctor may lower your dose as your symptoms improve.

  • Taken by mouth, typically three or four times daily
  • Dose may be reduced with symptom improvement — follow your prescriber's guidance
  • Not recommended for children under 12 (safety and effectiveness not established)
🤒Side effects — in detail

Like any medication, flavoxate can cause side effects. The most commonly reported ones include:

  • Dry mouth
  • Nausea or vomiting
  • Dizziness or vertigo
  • Headache
  • Drowsiness
  • Nervousness
  • Blurred vision or difficulty focusing
  • Rapid heartbeat (tachycardia) or palpitations

More serious reactions — including mental confusion (especially in older adults), skin rash or hives, fever, increased eye pressure, or a drop in white blood cells (leukopenia) — have been reported and should prompt a call to your doctor right away.

⚠️Warnings & precautions
  • Glaucoma: Flavoxate may increase pressure inside the eye. Anyone with glaucoma or suspected glaucoma should use this medication with caution and under close medical supervision.
  • Blocked passages: Do not take flavoxate if you have any obstruction in your stomach, intestines, or lower urinary tract, or conditions like achalasia, ileus, or gastrointestinal bleeding — these are absolute contraindications.
  • Older adults: Mental confusion has been reported, particularly in elderly patients. Caregivers should watch for this.
  • Children under 12: Safety and effectiveness have not been established — this medication is not recommended for this age group.
🔀What it interacts with

The FDA label for flavoxate does not specifically list drug, food, or supplement interactions. Always tell your doctor and pharmacist about every medication and supplement you take before starting flavoxate.

    This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.

    📋Before taking it
    • Tell your doctor if you have glaucoma or are being evaluated for eye pressure problems
    • Do not take this medication if you have a blockage in your stomach or intestines, bowel obstruction, ileus, achalasia, gastrointestinal bleeding, or a blockage in your lower urinary tract
    • Older adults should use with caution — confusion is a reported side effect in this group
    • Not for use in children under 12 years of age
    • Let your doctor know all other medications you are taking before starting flavoxate
    🚑If you take too much

    The FDA label does not describe specific overdose symptoms for flavoxate in people. Animal studies used to estimate lethal doses are included in the label but do not directly translate to human experience. If you think you or someone else has taken too much flavoxate, contact Poison Control or seek emergency medical care immediately. It is not known whether dialysis can remove flavoxate from the body.

    📡Pharmacodynamics — effects in the body

    Flavoxate directly relaxes smooth muscle in the urinary tract, reducing spasms that cause urgency, pain, and frequent urination. In a study of healthy adult men, the medication began to take effect in about 55 minutes, with peak effects measured at around 112 minutes after a dose. These effects help ease the discomfort of urinary tract inflammation without treating the infection causing it.

    🔬Pharmacokinetics — how your body processes it

    After an oral dose, flavoxate is absorbed and begins working within about an hour. About 57% of the drug is eliminated through the urine within 24 hours, indicating the kidneys play a key role in clearing the medication from the body.

    📦How to store it

    Store at 20° - 25°C (68° - 77°F) .

    📄 Written from Flavoxate’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →

    17

    Supplements & herbs that interact with Flavoxate

    17 supplements and herbal products have documented interactions with Flavoxate in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

    Severity mix
    • Major · 1
    • Moderate · 7
    • Minor · 9
    Every supplement checked against Flavoxate — ranked by severity The full interaction hub: 1 major · 7 moderate · 9 minor · every one linked to its full report. Check Flavoxate against your exact supplements

    Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

    🩺 Pharmacist Counseling Corner

    Quick, plain-English answers to the questions patients ask most about Flavoxate — the kind of thing our pharmacy team would talk through with you at the counter.

    Will flavoxate actually cure my bladder infection?
    No — and that's an important distinction. Flavoxate is a symptom reliever, not an antibiotic. It helps calm the spasms in your urinary tract that cause the burning, urgency, and frequent trips to the bathroom. To treat the actual infection, you'll need an antibiotic prescribed by your doctor. Flavoxate works alongside that treatment to make you more comfortable while the antibiotic does its job.
    How long does it take for flavoxate to start working?
    In a clinical study, flavoxate started working in about 55 minutes, with the strongest effect hitting around the 112-minute mark — so roughly two hours after your dose. You likely won't feel instant relief, but within an hour or two you should notice the urgency and discomfort beginning to ease. If your symptoms aren't improving after a few days, check in with your doctor.
    What side effects should I actually watch out for?
    The most common ones are dry mouth, nausea, dizziness, drowsiness, and blurred vision — annoying, but usually manageable. What you want to call your doctor about right away: confusion or unusual mental changes (this happens more in older adults), a skin rash or hives, fever, eye pain, or a very rapid heartbeat. These are less common but worth taking seriously.
    I have glaucoma — is it safe for me to take flavoxate?
    You'll want to talk to your doctor before taking it. Flavoxate can raise the pressure inside your eyes, which is a concern if you already have glaucoma or are at risk for it. Your doctor may still decide it's okay for you with careful monitoring, but it's definitely a conversation to have first — don't start it on your own.
    Can I give flavoxate to my child?
    Only if your child is over 12. Flavoxate has not been studied in children under 12 years of age, so safety and effectiveness in that age group are unknown. The medication is not recommended for younger kids. If your younger child is having urinary symptoms, check with their pediatrician for the right treatment option.
    Are there any medications or conditions that mean I absolutely cannot take flavoxate?
    Yes — there are a few situations where flavoxate is a firm no. You should not take it if you have a blockage anywhere in your stomach or intestines, a condition called achalasia (a swallowing disorder), gastrointestinal bleeding, or a blockage in your lower urinary tract. These are called contraindications, meaning the risks outweigh any benefit. Make sure your doctor knows your full medical history before you start.
    Is Flavoxate available over the counter?
    Flavoxate is dispensed by prescription according to its FDA labeling, so it isn't sold over the counter. Your prescriber and pharmacist will determine if it's appropriate for you.
    When was Flavoxate first available?
    Flavoxate has been available in the United States since at least 1970, based on FDA approval history (Drugs@FDA) and product marketing records.
    Who makes Flavoxate?
    Flavoxate is supplied by 5 manufacturers listed in the FDA NDC Directory, including Epic Pharma, LLC, Padagis US LLC, PuraCap Laboratories LLC dba Blu Pharmaceuticals.

    💬 Answers drafted from Flavoxate’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →

    🧰 Keep exploring

    💊 How Flavoxate comes

    Flavoxate is available in 1 form. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

    Tablet

    By mouth
    How this form is used
    What it may be used for
    • Flavoxate Hydrochloride tablets relieve urinary symptoms such as painful urination, urgency, frequency, and incontinence
    • Flavoxate Hydrochloride tablets are used alongside treatments for cystitis, prostatitis, urethritis, and related urinary tract conditions
    • Flavoxate Hydrochloride tablets are for symptom relief only — not for treating the underlying infection
    Important instructions
    • Flavoxate Hydrochloride tablets are taken by mouth three or four times a day for adults and children over 12
    • Flavoxate Hydrochloride tablets may be taken at a lower frequency once symptoms begin to improve, as directed by your doctor
    • Flavoxate Hydrochloride tablets are not recommended for children under 12 years of age
    Available strengths 1 strength
    6 FDA-listed product records

    📊 Flavoxate across the U.S. market

    How Flavoxate appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

    1
    Dose forms
    5
    Manufacturers
    1
    Brand names
    8
    FDA-listed product records
    1970
    First marketed

    Also listed with the FDA, not a patient dose form: Powder (2) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

    Epic Pharma, LLC25%
    Padagis US LLC25%
    PuraCap Laboratories LLC dba Blu Pharmaceuticals25%
    Recordati Industria Chimica E Farmaceutica Spa13%
    ScinoPharm Taiwan Ltd.13%

    Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

    📈 How widely Flavoxate is used

    A general measure of how commonly Flavoxate is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

    Think of this as a proxy for how widely Flavoxate is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

    337
    Medicaid prescriptions filled (Q1–Q4 2025)
    $14,598 gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

    How commonly is Flavoxate prescribed? Of the 1,596 medications we measure, Flavoxate ranks #1,404 by Medicaid prescriptions — more than 12% of them.

    Where Flavoxate ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5

    Utilization by Flavoxate product

    Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

    flavoxate hydrochloride 100 MG Oral Tablet

    337 Medicaid prescriptions (Q1–Q4 2025) 100% of Flavoxate prescriptions shown $14,598 gross reimbursement (before rebates) ≈ $43 per prescription (gross)

    Summed across the 2 of 5 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1095229

    Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

    Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Flavoxate, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 2 of 5 listed Flavoxate NDCs with Medicaid activity.

    🔍 Compare Flavoxate products

    A representative set of FDA-listed product records for Flavoxate — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

    Strength Route Manufacturer / Labeler Category Details
    💊Tablet
    100 mg Oral Epic Pharma, LLC × 2 listings ANDA View NDC →
    100 mg Oral Padagis US LLC × 2 listings ANDA View NDC →
    100 mg Oral PuraCap Laboratories LLC dba Blu Pharmaceuticals × 2 listings ANDA View NDC →
    💊Bulk drug substance
    25 kg/25 kg Recordati Industria Chimica E Farmaceutica Spa DRUG FOR FURTHER PROCESSING View NDC →
    1 kg/kg ScinoPharm Taiwan Ltd. BULK INGREDIENT View NDC →

    Showing 8 of 8 products — FDA National Drug Code Directory. See every product, package size and price: browse all 8 Flavoxate NDCs →

    RxNorm Concept Web — From Ingredient to Every Form and Strength

    This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

    Ingredient (IN) Flavoxate RxCUI 4440 1 dose form · 2 strengths
    1. Dose form (SCDF) Oral Tablet RxCUI 372200 In current FDA listings
      Clinical drug / strength (SCD) hydrochloride 100 MG RxCUI 1095229 hydrochloride 200 MG RxCUI 1095234

    Look up RxCUI 4440 in the RxCUI Atlas →

    RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

    🏷️ Sold under these brand names

    Urispas

    🏭 Manufacturers & labelers

    Epic Pharma, LLC 2 Padagis US LLC 2 PuraCap Laboratories LLC dba Blu Pharmaceuticals 2 Recordati Industria Chimica E Farmaceutica Spa 1 ScinoPharm Taiwan Ltd. 1

    RxNorm drug class

    Flavoxate belongs to the Cholinergic Muscarinic Antagonist class.

    Pharmacologic class Cholinergic Muscarinic Antagonist
    Drug family (ATC) Drugs for urinary frequency and incontinence
    How it works Cholinergic Muscarinic Antagonists

    Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

    🔬 Where this comes from

    Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

    📄
    FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective May 31, 2023
    🏭
    Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Flavoxate.
    📈
    Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
    🚨
    Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
    🧾 Clinical label set — FDA-filed SPL labels retained for Flavoxate after exact ingredient or ingredient-combination matching and applicable route/form matching
    Clinical labels in scope
    3
    NDC products indexed
    8
    Distinct labelers/manufacturers represented
    5
    Linked representative label
    Padagis US LLC
    Linked label effective
    May 31, 2023
    Composite sections available
    13
    Linked SPL Set ID
    a9c44c4b-5b3c-45bf-9bc9-ce858e3d06c5
    Linked SPL Document ID
    ff1c0ee9-75d2-478a-9152-0753be81ff11
    Open the linked representative label on DailyMed ↗
    NDC package records associated with this linked SPL 1

    How we combine label and product data

    HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 3 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.

    For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Padagis US LLC is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.

    This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.