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Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical

A combination eye ointment containing three antibiotics and a corticosteroid, used to treat eye inflammation when bacterial infection is present or likely.

Brand names Welly Polka First Aid KitKroger
Drug classes Aminoglycoside Antibacterial
Rx/OTC Form 1
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026 Content updated Oct 2, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 5 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

✓No current FDA shortage listed · checked Oct 6, 2026
Other forms & routes:
Ophthalmic
Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical at a glance The quick version — the full detail is in the Patient Information Guide below.
Dr. Brian Staiger, PharmD, BCPS
The Pharmacist’s Take By · Clinical pharmacist · Written

This eye ointment pairs three antibiotics (neomycin, polymyxin B and bacitracin) that kill common eye bacteria with hydrocortisone, a steroid that calms swelling, to treat eye inflammation when bacterial infection is present or likely; an older combination usually started by an eye doctor, it has been around since about 1995 and is available generically. Most people notice little beyond brief burning or irritation as it goes in. Watch for neomycin allergy, which looks like itchy, red, swollen eyelids that worsen instead of improving, and stop it if that happens. The steroid can also raise eye pressure, so use past 10 days needs pressure checks.

Clinical pearls

  • If you have ever had a herpes simplex eye infection, say so before starting, since the steroid can let it flare.
  • If an antibiotic skin ointment containing neomycin ever gave you a rash, mention it, because neomycin allergy is especially common.
  • Get rechecked if the eye is not clearly better within 2 days, because the steroid can hide a fungal or viral infection.
  • Mention glaucoma or recent cataract surgery first, since the steroid can raise eye pressure and slow healing.
How we write & review this content — our editorial policy →
How you get itPrescription and over the counter
Comes asEye ointment
Earliest FDA record1995
Companies listing it with the FDA3
FDA label last updatedFeb 2, 2022
FDA’s strongest warning (boxed)None on the label

Patient information guide A plain-language walkthrough of Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical, written from its FDA label.

What Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical is used for

▾

This combination ophthalmic ointment is used for inflammatory conditions of the eye when bacterial infection is present or at risk. It brings together three antibiotics and a corticosteroid in one product.

  • Inflammatory conditions of the conjunctiva (the lining of the eye and eyelid), cornea, and the front (anterior segment) of the eye — when bacterial infection is a concern
  • Chronic anterior uveitis (ongoing inflammation inside the front of the eye)
  • Eye inflammation caused by chemical, radiation, or thermal burns
  • Eye inflammation following penetration by a foreign body
  • Situations where dangerous numbers of bacteria are present or expected in the eye

The antibiotic ingredients target common bacterial eye pathogens including Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Haemophilus influenzae, Klebsiella/Enterobacter species, and Neisseria species. It does not provide adequate coverage against Serratia marcescens.

How Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical works

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This ointment has two types of active ingredients working together. Hydrocortisone is a corticosteroid that suppresses the eye's inflammatory response — reducing swelling, redness, and discomfort. The three antibiotics (neomycin, polymyxin B, and bacitracin) target and kill the bacteria most likely to infect the eye. Combining them in one formulation ensures the right dose of each ingredient is delivered together, improving convenience and compliance.

Because corticosteroids can reduce the eye's natural defenses against infection, pairing them with antibiotics in the same product helps guard against that risk while still controlling inflammation.

Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical dosage

▾

This ointment is applied directly to the eye (ophthalmic use). Follow your eye doctor's specific instructions for how often to apply it and for how long. Do not inject it into the eye — this product is for surface application only.

  • If you use it for 10 days or longer, your eye pressure should be routinely monitored by your provider
  • If your symptoms are not improving after 2 days, contact your prescriber for re-evaluation
  • Follow the labeled directions and your prescriber's guidance exactly — do not use more often or for longer than directed

Dosing details from the FDA-approved label

From the Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.

  • Triple Antibiotic Ointment – affected area (adults and children not otherwise specified in text)
    • Clean the affected area
    • Apply a small amount of this product (an amount equal to the surface area of the tip of a finger) on the area 1 to 3 times daily
    • May be covered with a sterile bandage
  • Hydrocortisone Cream – adults and children 2 years of age and older
    • Apply to affected area 3 to 4 times daily
  • Hydrocortisone Cream – children under 2 years of age
    • Do not use, consult a doctor
  • Hydrocortisone Cream – adults, external anal itching
    • When practical, cleanse the affected area with mild soap and warm water and rinse thoroughly or by patting or blotting with an appropriate cleansing pad
    • Gently dry by patting or blotting with toilet tissue or a soft cloth before application of this product
    • Apply to affected area 3 to 4 times daily
  • Hydrocortisone Cream – children under 12 years of age, external anal itching
    • Consult a doctor
Read the label’s full dosing text

Directions – Triple Antibiotic Ointment Clean the affected area Apply a small amount of this product (an amount equal to the surface area of the tip of a finger) on the area 1 to 3 times daily May be covered with a sterile bandage

Directions – Hydrocortisone Cream for adults and children 2 years of age and older: apply to affected area 3 to 4 times daily children under 2 years of age: do not use, consult a doctor adults for external anal itching when practical, cleanse the affected area with mild soap and warm water and rinse thoroughly or by patting or blotting with an appropriate cleansing pad gently dry by patting or blotting with toilet tissue or a soft cloth before application of this product children under 12 years of age: for external anal itching, consult a doctor

Read the full Dosage and Administration section on DailyMed →

Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical side effects

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The most common side effects involve local reactions to the antibiotic or corticosteroid components.

Common side effects

  • Eye itching or redness
  • Swelling of the eyelid or conjunctiva
  • Allergic skin-like reaction (sensitization) to the antibiotic ingredients
  • Temporary irritation or burning when applied
  • Elevated pressure inside the eye with long-term use
  • Slowed wound healing
  • Temporary irritation or burning when the ointment is applied
  • Elevated intraocular pressure (pressure inside the eye) with prolonged use
  • Posterior subcapsular cataract (a type of lens clouding) with extended corticosteroid use

When to get medical help

  • Call your doctor if your symptoms are not improving after 2 days of use
  • Seek medical attention for signs of severe allergic reaction, including anaphylaxis (sudden swelling, difficulty breathing)
  • Tell your doctor right away if you notice changes in vision or eye pain — these may be signs of increased pressure inside the eye or glaucoma
  • Contact your doctor if you notice a new or worsening eye infection — the corticosteroid can mask infections or allow secondary infections (bacterial, fungal, or viral) to develop
  • Tell your doctor if you notice persistent itching, redness, or failure of the eye to heal — this may be a sensitization reaction to the antibiotic

More serious reactions — including anaphylaxis (a severe, sudden allergic response) — have been reported rarely. Seek immediate medical attention if you have difficulty breathing, severe swelling, or any sudden worsening of symptoms.

Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical warnings and precautions

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  • Never inject this ointment into the eye — it is for surface (topical ophthalmic) use only.
  • Prolonged use can raise eye pressure, potentially causing glaucoma and optic nerve damage. Eye pressure should be monitored if used for 10 or more days.
  • Long-term use can cause a posterior subcapsular cataract (a specific type of cloudiness in the lens of the eye).
  • The corticosteroid may suppress the eye's immune defenses, increasing the risk of secondary infections — especially fungal and viral (including herpes simplex).
  • Do not use if you have a viral eye infection such as herpes simplex keratitis, chickenpox-related eye disease, or vaccinia — this ointment can make those infections worse.
  • Corticosteroids can thin the cornea or sclera over time; in people with already thin tissue, this raises the risk of eye perforation.
  • If the ointment causes itching, redness, or eyelid swelling that doesn't improve — or if the eye simply isn't healing — stop use and contact your doctor, as this may be a neomycin sensitization reaction.
  • Signs of infection can be hidden or worsened by the corticosteroid; if symptoms don't improve in 2 days, seek re-evaluation.

Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical interactions

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The FDA label for this product does not list specific drug-drug interactions.

    Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.

    Check Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical against a supplement or herb →

    Before taking Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical

    ▾
    • Do not use if you have a viral eye infection — including herpes simplex keratitis (dendritic keratitis), chickenpox (varicella), or vaccinia — as the corticosteroid can worsen these conditions
    • Do not use if you have a fungal or mycobacterial (e.g., tuberculosis-related) eye infection
    • Tell your doctor if you are allergic to neomycin, polymyxin B, bacitracin, or hydrocortisone — allergic reactions to neomycin in particular are relatively common with topical antibiotic products
    • Tell your doctor if you have glaucoma or elevated eye pressure — corticosteroids can raise intraocular pressure further
    • Tell your doctor if you have recently had cataract surgery — corticosteroid use may delay healing and increase the risk of certain post-surgical complications
    • Use with caution if your cornea or sclera is known to be thin — there is a risk of perforation with corticosteroid use in that setting
    • Use with great caution for herpes simplex eye disease — if it must be used, frequent monitoring with a slit lamp microscope is recommended

    What Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical does in the body

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    The corticosteroid component (hydrocortisone) reduces inflammation in the eye by suppressing the body's immune response. This decreases swelling (edema), redness, and discomfort in the affected ocular tissues. However, this immune suppression also reduces the eye's natural defenses against infection, which is why the antibiotic components are included. The antibiotics act against susceptible bacterial strains commonly found in eye infections.

    How to store Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical

    ▾

    Store at 20° to 25°C (68° to 77°F) . KEEP OUT OF REACH OF CHILDREN apexa™ Manufactured by: Akorn Inc.

    Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

    Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical: pharmacist answers to common questions

    Quick, plain-English answers to the questions patients ask most about Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical — the kind of thing our pharmacy team would talk through with you at the counter.

    What exactly is this eye ointment used for?

    ▾
    It's used when your eye is both inflamed and infected — or when there's a real risk of infection. The corticosteroid (hydrocortisone) calms the inflammation and swelling, while the three antibiotics (neomycin, polymyxin B, and bacitracin) fight the bacteria causing or threatening an infection. Your eye doctor may prescribe it for conditions like bacterial conjunctivitis with inflammation, corneal inflammation, or eye injuries from burns or foreign bodies.

    How do I apply it to my eye?

    ▾
    Apply the ointment directly to the eye as directed by your eye doctor. Do not inject it into the eye — it's only for surface application. If you're not sure of the right technique, ask your pharmacist or doctor to show you. Follow the schedule your prescriber gives you, and don't use it more often or for longer than recommended.

    What side effects should I watch for?

    ▾
    The most common issue is a sensitivity reaction to the antibiotic ingredient — usually showing up as itching, redness, or swelling of the eyelid or around the eye. You may also notice some temporary irritation right when you apply it. If your eye doesn't seem to be healing, or if symptoms are getting worse instead of better after 2 days, that's a signal to call your doctor. With longer-term use, your eye doctor will want to check your eye pressure, since this type of ointment can raise it over time.

    Is it safe to use if I have a history of herpes eye infection?

    ▾
    This is a really important question. This ointment should generally NOT be used if you have an active herpes simplex eye infection — the corticosteroid in it can actually make that type of infection worse. If your doctor knows your history and still prescribes it, you'll need close monitoring with an instrument called a slit lamp during treatment. Always tell your eye doctor about any history of eye herpes before starting this ointment.

    Can I use it for longer than 10 days?

    ▾
    Only if your doctor directs you to. If you use it for 10 days or more, your doctor should check the pressure inside your eye regularly — prolonged use of the corticosteroid can raise that pressure and, over time, potentially cause glaucoma or damage the optic nerve. Don't extend your use beyond what's prescribed without checking in with your provider.

    Is this ointment safe if I'm allergic to neomycin?

    ▾
    No — if you have a known allergy to neomycin, you should not use this product, as neomycin is one of its main ingredients. Allergic reactions to topical neomycin are actually more common than with many other antibiotic ingredients. Signs of a reaction include itching, redness, or swelling around the eye. Tell your doctor and pharmacist about any antibiotic allergies before starting this ointment.

    Is Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical available over the counter?

    ▾
    Both. Some Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical products are sold over the counter and others need a prescription. According to their FDA listings, the eye ointment form needs a prescription. The package says which kind you have. Your pharmacist can tell you which product is right for you.

    When was Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical first available?

    ▾
    The earliest FDA record we hold for Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical is from 1995: its first approval in Drugs@FDA or its earliest product listing in the NDC Directory, whichever is older. Many older medicines were in use before their first formal FDA approval, so this is the earliest date on record, not necessarily when Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical was first used.

    Who makes Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical?

    ▾
    3 companies currently list Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical products in the FDA's NDC Directory, including Bausch & Lomb Incorporated, Dongguan Shenglian Tins Products Co., Ltd., Kroger. That count includes repackagers and distributors as well as manufacturers (companies that sell only the raw ingredient are not counted), so fewer companies actually make it; the label on your bottle names the one that supplied yours.

    Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

    More about Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical on HelloPharmacist

    🌿Drug & Supplement CheckerNeomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical NDCs & costs 🅰️Browse Drugs A–ZLook up any medication
    Detailed data & references for Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here. Each section below opens on a tap.

    Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical forms and strengths (how it comes)

    Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical is available in 1 form. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

    Need a version that does not list lactose, a gluten source, a dye or gelatin? Inactive ingredients differ by manufacturer: see Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical inactive ingredients by manufacturer.

    Eye ointment

    In the eye
    Brands Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Hydrocortisone Neo Polycin HC
    How this form is used
    What it may be used for
    • Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Hydrocortisone Ophthalmic Ointment is used for inflammatory eye conditions — including conjunctivitis, corneal inflammation, and anterior uveitis — where bacterial infection is present or likely
    • Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Hydrocortisone Ophthalmic Ointment is used for eye inflammation resulting from chemical, radiation, or thermal burns, or from a foreign body in the eye
    • Active against common bacterial eye pathogens including Staphylococcus aureus, Pseudomonas aeruginosa, and Streptococcus pneumoniae; does not provide adequate coverage against Serratia marcescens
    Important instructions
    • Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Hydrocortisone Ophthalmic Ointment is applied to the eye (ophthalmic route only) — never injected into the eye
    • Follow your prescriber's instructions for how often to apply; if used for 10 days or longer, your eye pressure should be routinely checked
    • If signs and symptoms do not improve after 2 days, contact your eye care provider for re-evaluation
    • Stop use and tell your doctor if you notice itching, swelling, or redness of the eyelid or conjunctiva — these may be signs of a sensitization reaction
    Available strengths 2 strengths
    NEOMYCIN SULFATE 3.5 mg/g; POLYMYXIN B SULFATE 10000 [USP'U]/g; BACITRACIN ZINC 400 [USP'U]/g; HYDROCORTISONE 10 mg/g 400 [USP'U]/g / 10 mg/g / 3.5 mg/g / 10000 [USP'U]/g
    3 FDA-listed product records ⓘ

    Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical on the U.S. market: products, makers and brands

    How Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

    3 companies list 3 Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical product records with the FDA, mostly as eye ointment; the earliest marketing or approval year on record is 1995. Brand names on the directory include Welly Polka First Aid Kit, Kroger; the rest are generics.

    1
    Dose forms ⓘ
    3
    Labelers (makers, repackagers, distributors)
    3
    Brand names
    3
    FDA-listed product records ⓘ
    1995
    Earliest FDA record ⓘ

    Also listed with the FDA, not a patient dose form: Kit (3) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

    Bausch & Lomb Incorporated33%
    Dongguan Shenglian Tins Products Co., Ltd.33%
    Kroger33%

    Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

    How widely Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical is used (Medicaid data)

    A general measure of how commonly Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1 2025 – Q1 2026, summed across every form and brand of the drug.

    Think of this as a proxy for how widely Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

    911
    Medicaid prescriptions filled (Q1 2025 – Q1 2026)
    $25,290 gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

    How commonly is Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical prescribed? Of the 1,601 medications we measure, Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical ranks #1,297 by Medicaid prescriptions — more than 19% of them.

    Where Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical ranks among the drugs we measure · Q1 2025 – Q1 2026 · neighbors ±5
    Total prescriptions — #1,297 of 1,601
    #1,292 Pentamidine Injection 931 Rx #1,293 Neomycin, Polymyxin, B... 928 Rx #1,294 Elacestrant 927 Rx #1,295 Bleomycin 918 Rx #1,296 Phentermine and Topira... 914 Rx #1,297 Neomycin, Polymyxin, B... 911 Rx #1,298 Teclistamab-cqyv Injec... 895 Rx #1,299 Colistimethate Injecti... 894 Rx #1,300 Metoclopramide Nasal S... 893 Rx #1,301 Nicardipine 890 Rx #1,302 Carbidopa / Entacapone... 868 Rx

    Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 2 of 8 listed Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical NDCs with Medicaid activity.

    Compare Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical products

    A representative set of FDA-listed product records for Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

    Strength Route Manufacturer / Labeler Category ⓘ Details
    💊Eye ointment
    NEOMYCIN SULFATE 3.5 mg/g; POLYMYXIN B SULFATE 10000 [USP'U]/g; BACITRACIN ZINC 400 [USP'U]/g; HYDROCORTISONE 10 mg/g Ophthalmic Bausch & Lomb Incorporated ANDA View NDC →
    💊Kits
    — — Dongguan Shenglian Tins Products Co., Ltd. OTC MONOGRAPH DRUG View NDC →
    — Topical Kroger OTC MONOGRAPH DRUG View NDC →

    Showing 3 of 3 products — FDA National Drug Code Directory.

    Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical recall history

    A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.

    The FDA’s enforcement reports list no Neomycin, Polymyxin, Bacitracin, and Hydrocortisone recalls since July 2021.

    ✅No Neomycin, Polymyxin, Bacitracin, and Hydrocortisone recalls on record since July 2021

    Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.

    RxNorm Concept Web — From Ingredient to Every Form and Strength

    This page starts with one exact multiple-ingredient concept (MIN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). A product with a different ingredient combination belongs on a different page.

    Multiple ingredients (MIN) Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical RxCUI 689623 1 dose form · 1 strength

    Look up RxCUI 689623 in the RxCUI Atlas →

    RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

    💵 What Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical costs pharmacies (NADAC benchmark)

    The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.

    FormStrengthPharmacy acquisition benchmark
    Ointment · Ophthalmic 400; 10; 3.5; 10000 [USP'U]/g; mg/g; mg/g; [USP'U]/g $5.52 per gram NDC details & price history
    Ointment · Ophthalmic NEOMYCIN SULFATE 3.5 mg/g; POLYMYXIN B SULFATE 10000 [USP'U]/g; BACITRACIN ZINC 400 [USP'U]/g; HYDROCORTISONE 10 mg/g $5.52 per gram NDC details & price history
    Why show this? Your out-of-pocket cost depends on insurance, pharmacy markup, and discounts — but the acquisition benchmark tells you whether the medication itself is inexpensive or costly, which strengths cost more per dose, and whether a cash-price quote is in a reasonable range. Each row links to the NDC-level record with its full price history.

    Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.

    Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical brand names

    Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical is sold under 2 brand names in the FDA directory — Welly Polka First Aid Kit, Kroger. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

    Welly Polka First Aid Kit Kroger

    Who makes Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical: manufacturers and labelers

    3 companies list Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical products with the FDA. By number of product records, the largest are Bausch & Lomb Incorporated, Dongguan Shenglian Tins Products Co., Ltd., Kroger. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

    Bausch & Lomb Incorporated 1 Dongguan Shenglian Tins Products Co., Ltd. 1 Kroger 1

    Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical drug class (RxNorm)

    Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical belongs to the Other antibiotics for topical use class.

    Drug family (ATC) Other antibiotics for topical use, Other antibacterials, Antibiotics

    Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

    Sources for this Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical page

    Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

    📄
    FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Feb 2, 2022
    🏭
    Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical.
    📈
    Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
    🚨
    Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
    🧾 Clinical label set — FDA-filed SPL labels retained for Neomycin, Polymyxin, Bacitracin, and Hydrocortisone Topical after exact ingredient or ingredient-combination matching and applicable route/form matching
    Clinical labels in scope
    5
    Finished products in the current FDA directory
    3
    Companies listing them (makers, repackagers, distributors)
    3
    FDA labeler codes behind them ⓘ
    3
    Linked representative label ⓘ
    Akorn
    Linked label effective
    Feb 2, 2022
    Composite sections available
    14
    Linked SPL Set ID
    ce7ded34-66ab-4b6d-a9d7-fcf0c8d86eaa
    Linked SPL Document ID
    4eb947c7-2da9-4ce6-8d13-06a4539a6e96
    Open the linked representative label on DailyMed ↗

    How this page is built

    HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Akorn is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →