Ritonavir

Generic name: Pronounced as (ri toe' na veer)
Brand names
  • Norvir®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 01/15/2021

Taking ritonavir with certain other medications may cause serious or life-threatening side effects. Tell your doctor if you are taking any of the following medications: ergot medications such as dihydroergotamine (D.H.E. 45, Migranal), ergotamine (Ergomar, in Cafergot, in Migergot), ergonovine, and methylergonovine (Methergine); medications for irregular heartbeat such as amiodarone (Cordarone, Nexterone, Pacerone), flecainide, propafenone (Rhythmol), and quinidine (in Nuedexta); and sedatives or sleeping pills such as midazolam (Versed) and triazolam (Halcion). Your doctor will probably tell you not to take ritonavir if you are taking any of these medications.

Ritonavir is used along with other medications to treat human immunodeficiency virus (HIV) infection. Ritonavir is in a class of medications called protease inhibitors. It works by decreasing the amount of HIV in the blood. Although ritonavir does not cure HIV, it may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer. Taking these medications along with practicing safer sex and making other lifestyle changes may decrease the risk of transmitting the HIV virus to other people.

Ritonavir comes as a capsule, a tablet, and a solution (liquid) to take by mouth. It is usually taken twice a day with meals. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take ritonavir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of ritonavir and gradually increase your dose, not more often than once every 2 to 3 days. Follow these directions carefully.

Swallow ritonavir tablets whole. Do not split, chew, or crush them.

If you are taking the oral solution, use a dose measuring spoon, syringe, or cup to measure the correct amount of liquid needed for each dose. Do not use a regular household spoon. You may take the solution by itself, or you may improve the taste by mixing it with 8 ounces of chocolate milk or Ensure or Advera brand dietary supplements. If you mix the medication with one of these liquids, you must drink the mixture no longer than 1 hour after you mix it.

If your doctor tells you to stop taking ritonavir capsules and start taking the tablets instead, you may experience more side effects such as nausea, vomiting, stomach pain, and diarrhea shortly after you switch. These symptoms may improve as your body adjusts to the tablets.

Continue to take ritonavir even if you feel well. Do not stop taking ritonavir without talking to your doctor. If you miss doses, take less than the prescribed dose, or stop taking ritonavir, your condition may become more difficult to treat.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Before taking ritonavir,

  • tell your doctor and pharmacist if you are allergic to ritonavir, any other medications, or any of the ingredients in ritonavir tablets, capsules, or solution. Ask your pharmacist for a list of the ingredients.

  • tell your doctor if you are taking any of the medications in the IMPORTANT WARNING section or any of the following: alfuzosin (Uroxatral), apalutamide (Erleada), cisapride (Propulsid) (not available in U.S.), colchicine (Colcrys, Mitigare) in people with kidney or liver disease, dronedarone (Multaq), lomitapide (Juxtapid), lovastatin (Altoprev), lurasidone (Latuda), pimozide (Orap), ranolazine (Ranexa), sildenafil (only Revatio brand used for lung disease), simvastatin (Zocor, in Vytorin), St. John's wort, or voriconazole (Vfend). Your doctor will probably tell you not to take ritonavir if you are taking one or more of these medications.

  • also tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven) and rivaroxaban (Xarelto); antidepressants such as amitriptyline, bupropion (Aplenzin, Forfivo XL, Wellbutrin, Zyban, others), desipramine (Norpramin), fluoxetine (Prozac), nefazodone, nortriptyline, paroxetine (Paxil), and trazodone; atovaquone (Mepron, in Malarone); bedaquiline (Sirturo); beta-blockers such as metoprolol (Lopressor, Toprol XL, in Dutoprol, in Lopressor HCT) and timolol; bosentan (Tracleer); buspirone; calcium channel blockers such as diltiazem (Cardizem, Cartia, Tiazac, others), nifedipine (Adalat, Afeditab CR, Procardia), and verapamil (Calan, Covera, Verelan, in Tarka); cholesterol-lowering medications such as atorvastatin (Lipitor, in Caduet) and rosuvastatin (Crestor); clarithromycin (Biaxin, in PrevPac); clorazepate (Gen-Xene, Tranxene); colchicine (Colcrys, Mitigare); certain medications for cancer such as abemaciclib (Verzenio), dasatinib (Sprycel), encorafenib (Braftovi), ibrutinib (Imbruvica), ivosidenib (Tibsovo), neratinib (Nerlynx), nilotinib (Tasigna), venetoclax (Venclexta), vinblastine, and vincristine; dexamethasone; diazepam (Diastat, Valium); digoxin (Lanoxin); dronabinol (Marinol); elagolix (Orilissa); estazolam; fentanyl (Duragesic, Subsys), fostamatinib (Tavalisse), certain medications for hepatitis C virus (HCV) such as boceprevir (no longer available in the U.S.; Victrelis), glecaprevir and pibrentasvir (Mavyret), and simeprevir (no longer available in U.S.; Olysio); itraconazole (Onmel, Sporanox); ketoconazole (Nizoral); lidocaine (Lidoderm; in Xylocaine with Epinephrine); other medications for HIV such as atazanavir (Reyataz, in Evotaz), darunavir (Prezista, in Prezcobix), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), maraviroc (Selzentry), saquinavir (Invirase), and tipranavir (Aptivus); medications for erectile dysfunction such as avanafil (Stendra), sildenafil (Viagra), tadalafil (Adcirca, Cialis), and vardenafil (Levitra); medications that suppress the immune system such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune) and tacrolimus (Astagraf XL, Prograf); certain medications for seizures such as carbamazepine (Epitol, Equetro, Tegretol, others), clonazepam (Klonopin), divalproex (Depakote), ethosuximide (Zarontin), lamotrigine (Lamictal), and phenytoin (Dilantin, Phenytek); meperidine (Demerol); methadone (Dolophine, Methadose); methamphetamine (Desoxyn); mexiletine; perphenazine; quetiapine (Seroquel); quinine (Qualaquin); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); risperidone; salmeterol (Serevent, in Advair); oral or inhaled steroids such as betamethasone, budesonide (Pulmicort), ciclesonide (Alvesco, Omnaris), dexamethasone, fluticasone (Flonase, Flovent, in Advair), methylprednisolone (Medrol). mometasone (in Dulera). prednisone, and triamcinolone; theophylline (Theo 24, Uniphyl, others); thioridazine; and zolpidem (Ambien, Edluar, Intermezzo, others). Many other medications may also interact with ritonavir, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • if you are taking ritonavir oral suspension, also tell your doctor if you are taking disulfiram (Antabuse) or metronidazole (Flagyl, Nuvessa, Vandazole).

  • tell your doctor if you have or have ever had a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death), diabetes, hemophilia, high cholesterol or triglycerides (fats) in the blood, or heart or liver disease, including hepatitis B or C.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking ritonavir, call your doctor immediately. You should not breastfeed if you are infected with HIV or if you are taking ritonavir.

  • you should know that ritonavir may decrease the effectiveness of hormonal contraceptives (birth control pills, patches, rings, or injections). Talk to your doctor about using another form of birth control.

  • you should be aware that your body fat may increase or move to different areas of your body, such as your upper back, neck (''buffalo hump''), breasts, and around your stomach. You may notice a loss of body fat from your face, legs, and arms.

  • you should know that you may experience hyperglycemia (increases in your blood sugar) while you are taking this medication, even if you do not already have diabetes. Tell your doctor immediately if you have any of the following symptoms while you are taking ritonavir: extreme thirst, frequent urination, extreme hunger, blurred vision, or weakness. It is very important to call your doctor as soon as you have any of these symptoms, because high blood sugar that is not treated can cause a serious condition called ketoacidosis. Ketoacidosis may become life-threatening if it is not treated at an early stage. Symptoms of ketoacidosis include dry mouth, nausea and vomiting, shortness of breath, breath that smells fruity, and decreased consciousness.

  • you should know that while you are taking medications to treat HIV infection, your immune system may get stronger and begin to fight other infections that were already in your body. This may cause you to develop symptoms of those infections. If you have new or worsening symptoms after starting treatment with ritonavir, be sure to tell your doctor.

Unless your doctor tells otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Ritonavir may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • drowsiness

    • diarrhea

    • gas

    • heartburn

    • change in ability to taste food

    • headache

    • numbness, burning, or tingling of the hands, feet, or area around the mouth

    • muscle or joint pain

    • stomach pain, nausea, and vomiting

  • Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment:

    • blistering or peeling of the skin

    • rash

    • hives

    • swelling of the eyes, face, tongue, lips, or throat

    • tightening of the throat

    • difficulty breathing or swallowing

    • nausea

    • vomiting

    • stomach pain

    • excessive tiredness

    • lack of energy

    • loss of appetite

    • pain in the upper right part of the stomach

    • yellowing of the skin or eyes

    • dizziness

    • lightheadedness

    • loss of consciousness

    • irregular heartbeat

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

  • Ritonavir may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets and solution at room temperature. Do not refrigerate the solution and do not let it get too hot or too cold. It is best to refrigerate ritonavir capsules, but you may also store them at room temperature for up to 30 days.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

It is especially important to get medical help right away if a child drinks more than the usual dose of the solution. The solution contains a large amount of alcohol that could be very harmful to a child.

Symptoms of overdose may include the following:

  • numbness, burning, or tingling of the hands or feet

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to ritonavir.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Moxifloxacin.
Repaglinide Repaglinide The serum concentration of Repaglinide can be increased when it is combined with Ritonavir.
Montelukast Montelukast The serum concentration of Montelukast can be increased when it is combined with Ritonavir.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection The therapeutic efficacy of Insulin glargine can be decreased when used in combination with Ritonavir.
Leflunomide Leflunomide Ritonavir may decrease the excretion rate of Leflunomide which could result in a higher serum level.
Delavirdine Delavirdine The serum concentration of Ritonavir can be increased when it is combined with Delavirdine.
Nevirapine Nevirapine The serum concentration of Nevirapine can be increased when it is combined with Ritonavir.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Ritonavir.
Dolasetron Dolasetron The serum concentration of Dolasetron can be increased when it is combined with Ritonavir.
Alendronate Alendronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Alendronic acid.
Aminophylline Aminophylline The serum concentration of Aminophylline can be increased when it is combined with Ritonavir.
Anagrelide Anagrelide The metabolism of Anagrelide can be increased when combined with Ritonavir.
Calcium Carbonate Calcium Carbonate Calcium carbonate can cause a decrease in the absorption of Ritonavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Candesartan Candesartan The metabolism of Candesartan can be increased when combined with Ritonavir.
Cilostazol Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Ritonavir.
Clopidogrel Clopidogrel The serum concentration of Clopidogrel can be increased when it is combined with Ritonavir.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The serum concentration of Erythromycin can be increased when it is combined with Ritonavir.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The serum concentration of Ritonavir can be increased when it is combined with Conjugated estrogens.
Fenofibrate Fenofibrate The serum concentration of Fenofibrate can be increased when it is combined with Ritonavir.
Guanfacine Guanfacine The metabolism of Guanfacine can be decreased when combined with Ritonavir.
Magnesium Hydroxide Magnesium Hydroxide Magnesium hydroxide can cause a decrease in the absorption of Ritonavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Magnesium Oxide Magnesium Oxide Magnesium oxide can cause a decrease in the absorption of Ritonavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Methylergonovine Methylergonovine The serum concentration of Methylergometrine can be increased when it is combined with Ritonavir.
Miglitol Miglitol The therapeutic efficacy of Miglitol can be decreased when used in combination with Ritonavir.
Mycophenolate Mycophenolate The metabolism of Mycophenolic acid can be increased when combined with Ritonavir.
Nafarelin Nafarelin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Nafarelin.
Paregoric Paregoric The serum concentration of Morphine can be increased when it is combined with Ritonavir.
Penbutolol Penbutolol The metabolism of Acebutolol can be decreased when combined with Ritonavir.
Prednisone Prednisone The serum concentration of Ritonavir can be increased when it is combined with Prednisone.
Ranitidine Ranitidine The metabolism of Ritonavir can be decreased when combined with Ranitidine.
Reserpine Reserpine Reserpine may decrease the excretion rate of Ritonavir which could result in a higher serum level.
Sumatriptan Sumatriptan Ritonavir may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Ritonavir.
Tizanidine Tizanidine The metabolism of Tizanidine can be increased when combined with Ritonavir.
Triamcinolone Triamcinolone The serum concentration of Triamcinolone can be increased when it is combined with Ritonavir.
Zolmitriptan Zolmitriptan The metabolism of Zolmitriptan can be increased when combined with Ritonavir.
Doxycycline Injection Doxycycline Injection The serum concentration of Doxycycline can be increased when it is combined with Ritonavir.
Famotidine Injection Famotidine Injection Famotidine can cause a decrease in the absorption of Ritonavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Fluconazole Injection Fluconazole Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Ritonavir.
Foscarnet Injection Foscarnet Injection The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Foscarnet.
Hydromorphone Injection Hydromorphone Injection The metabolism of Hydromorphone can be decreased when combined with Ritonavir.
Levofloxacin Injection Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Levofloxacin.
Meperidine Injection Meperidine Injection The serum concentration of normeperidine, an active metabolite of Meperidine, can be increased when used in combination with Ritonavir.
Methylprednisolone Injection Methylprednisolone Injection The serum concentration of Methylprednisolone can be increased when it is combined with Ritonavir.
Metoclopramide Injection Metoclopramide Injection The serum concentration of Metoclopramide can be increased when it is combined with Ritonavir.
Metronidazole Injection Metronidazole Injection The risk or severity of adverse effects can be increased when Ritonavir is combined with Metronidazole.
Morphine Injection Morphine Injection The serum concentration of Morphine can be increased when it is combined with Ritonavir.
Pamidronate Injection Pamidronate Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Pamidronic acid is combined with Ritonavir.
Zidovudine Injection Zidovudine Injection The serum concentration of Zidovudine can be increased when it is combined with Ritonavir.
Altretamine Altretamine The metabolism of Amphetamine can be decreased when combined with Ritonavir.
Cyclosporine Cyclosporine The serum concentration of Cyclosporine can be increased when it is combined with Ritonavir.
Ondansetron Ondansetron The serum concentration of Ondansetron can be increased when it is combined with Ritonavir.
Granisetron Granisetron The serum concentration of Granisetron can be increased when it is combined with Ritonavir.
Torsemide Torsemide The metabolism of Torasemide can be decreased when combined with Ritonavir.
Olanzapine Olanzapine The metabolism of Olanzapine can be decreased when combined with Ritonavir.
Alosetron Alosetron The serum concentration of Alosetron can be increased when it is combined with Ritonavir.
Dofetilide Dofetilide The serum concentration of Dofetilide can be increased when it is combined with Ritonavir.
Entacapone Entacapone The metabolism of Ritonavir can be decreased when combined with Entacapone.
Eprosartan Eprosartan The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Eprosartan.
Hydroxychloroquine Hydroxychloroquine The serum concentration of Ritonavir can be increased when it is combined with Hydroxychloroquine.
Meloxicam Meloxicam The serum concentration of Meloxicam can be increased when it is combined with Ritonavir.
Oxcarbazepine Oxcarbazepine The metabolism of Ritonavir can be increased when combined with Oxcarbazepine.
Pantoprazole Pantoprazole The serum concentration of Ritonavir can be increased when it is combined with Pantoprazole.
Risedronate Risedronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Risedronic acid.
Telmisartan Telmisartan Telmisartan may decrease the excretion rate of Ritonavir which could result in a higher serum level.
Zaleplon Zaleplon The serum concentration of Zaleplon can be increased when it is combined with Ritonavir.
Anakinra Anakinra The metabolism of Ritonavir can be increased when combined with Anakinra.
Desloratadine Desloratadine The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Desloratadine.
Trimipramine Trimipramine The metabolism of Trimipramine can be decreased when combined with Ritonavir.
Etanercept Injection Etanercept Injection The metabolism of Ritonavir can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Ritonavir can be increased when combined with Armodafinil.
Tenofovir Tenofovir The serum concentration of Tenofovir can be increased when it is combined with Ritonavir.
Sirolimus Sirolimus The serum concentration of Sirolimus can be increased when it is combined with Ritonavir.
Dutasteride Dutasteride The metabolism of Dutasteride can be decreased when combined with Ritonavir.
Eplerenone Eplerenone The metabolism of Eplerenone can be decreased when combined with Ritonavir.
Escitalopram Escitalopram The serum concentration of Escitalopram can be increased when it is combined with Ritonavir.
Olmesartan Olmesartan Olmesartan may decrease the excretion rate of Ritonavir which could result in a higher serum level.
Zonisamide Zonisamide The serum concentration of Zonisamide can be increased when it is combined with Ritonavir.
Adalimumab Injection Adalimumab Injection The metabolism of Ritonavir can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Ritonavir.
Atomoxetine Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Ritonavir.
Ezetimibe Ezetimibe The metabolism of Ezetimibe can be increased when combined with Ritonavir.
Atazanavir Atazanavir The serum concentration of Atazanavir can be increased when it is combined with Ritonavir.
Enfuvirtide Injection Enfuvirtide Injection The serum concentration of Enfuvirtide can be increased when it is combined with Ritonavir.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Ritonavir.
Eletriptan Eletriptan The metabolism of Eletriptan can be decreased when combined with Ritonavir.
Mefloquine Mefloquine The serum concentration of Ritonavir can be increased when it is combined with Mefloquine.
Rosuvastatin Rosuvastatin The serum concentration of Rosuvastatin can be increased when it is combined with Ritonavir.
Vardenafil Vardenafil The serum concentration of Vardenafil can be increased when it is combined with Ritonavir.
Alfuzosin Alfuzosin The serum concentration of Alfuzosin can be increased when it is combined with Ritonavir.
Aprepitant Aprepitant The serum concentration of Aprepitant can be increased when it is combined with Ritonavir.
Tegaserod Tegaserod The metabolism of Tegaserod can be decreased when combined with Ritonavir.
Tadalafil Tadalafil The serum concentration of Tadalafil can be increased when it is combined with Ritonavir.
Fosamprenavir Fosamprenavir The serum concentration of amprenavir, an active metabolite of Fosamprenavir, can be increased when used in combination with Ritonavir.
Frovatriptan Frovatriptan The metabolism of Frovatriptan can be increased when combined with Ritonavir.
Gemifloxacin Gemifloxacin The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Gemifloxacin.
Progesterone Progesterone The serum concentration of Progesterone can be decreased when it is combined with Ritonavir.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Ritonavir.
Infliximab Injection Infliximab Injection The metabolism of Ritonavir can be increased when combined with Infliximab.
Protriptyline Protriptyline The metabolism of Protriptyline can be decreased when combined with Ritonavir.
Rifaximin Rifaximin The serum concentration of Rifaximin can be increased when it is combined with Ritonavir.
Duloxetine Duloxetine The serum concentration of Duloxetine can be increased when it is combined with Ritonavir.
Norethindrone Norethindrone The serum concentration of Norethisterone can be decreased when it is combined with Ritonavir.
Tinidazole Tinidazole The serum concentration of Tinidazole can be increased when it is combined with Ritonavir.
Trospium Trospium The metabolism of Ritonavir can be decreased when combined with Trospium.
Bosentan Bosentan The serum concentration of Bosentan can be increased when it is combined with Ritonavir.
Cinacalcet Cinacalcet The serum concentration of Cinacalcet can be increased when it is combined with Ritonavir.
Erlotinib Erlotinib The metabolism of Erlotinib can be decreased when combined with Ritonavir.
Eszopiclone Eszopiclone The serum concentration of Eszopiclone can be increased when it is combined with Ritonavir.
Ganciclovir Ganciclovir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Ganciclovir.
Insulin Aspart (rDNA Origin) Injection Insulin Aspart (rDNA Origin) Injection The therapeutic efficacy of Insulin aspart can be decreased when used in combination with Ritonavir.
Solifenacin Solifenacin The serum concentration of Solifenacin can be increased when it is combined with Ritonavir.
Voriconazole Voriconazole The serum concentration of Voriconazole can be decreased when it is combined with Ritonavir.
Dextroamphetamine Dextroamphetamine The metabolism of Amphetamine can be decreased when combined with Ritonavir.
Entecavir Entecavir The metabolism of Entecavir can be increased when combined with Ritonavir.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The metabolism of Ritonavir can be decreased when combined with Peginterferon alfa-2b.
Pramlintide Injection Pramlintide Injection The therapeutic efficacy of Pramlintide can be decreased when used in combination with Ritonavir.
Exenatide Injection Exenatide Injection The therapeutic efficacy of Exenatide can be decreased when used in combination with Ritonavir.
Ibandronate Ibandronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Ibandronate.
Ramelteon Ramelteon The serum concentration of Ramelteon can be increased when it is combined with Ritonavir.
Darifenacin Darifenacin The serum concentration of Darifenacin can be increased when it is combined with Ritonavir.
Fentanyl Fentanyl The metabolism of Fentanyl can be decreased when combined with Ritonavir.
Pregabalin Pregabalin The risk or severity of QTc prolongation can be increased when Pregabalin is combined with Ritonavir.
Deferasirox Deferasirox The metabolism of Deferasirox can be increased when combined with Ritonavir.
Tipranavir Tipranavir The serum concentration of Tipranavir can be increased when it is combined with Ritonavir.
Felbamate Felbamate The serum concentration of Felbamate can be increased when it is combined with Ritonavir.
Insulin Detemir (rDNA Origin) Injection Insulin Detemir (rDNA Origin) Injection The therapeutic efficacy of Insulin detemir can be decreased when used in combination with Ritonavir.
Ranolazine Ranolazine The serum concentration of Ritonavir can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Ritonavir can be increased when combined with Abatacept.
Rasagiline Rasagiline The metabolism of Rasagiline can be increased when combined with Ritonavir.
Imatinib Imatinib The serum concentration of Imatinib can be increased when it is combined with Ritonavir.
Sitagliptin Sitagliptin The serum concentration of Sitagliptin can be increased when it is combined with Ritonavir.
Gefitinib Gefitinib The serum concentration of Gefitinib can be increased when it is combined with Ritonavir.
Albuterol Albuterol The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Salbutamol.
Paliperidone Paliperidone The serum concentration of Paliperidone can be increased when it is combined with Ritonavir.
Exemestane Exemestane The serum concentration of Exemestane can be increased when it is combined with Ritonavir.
Bortezomib Bortezomib The serum concentration of Bortezomib can be increased when it is combined with Ritonavir.
Clofarabine Injection Clofarabine Injection Ritonavir may decrease the excretion rate of Clofarabine which could result in a higher serum level.
Influenza Vaccine, Live Intranasal Influenza Vaccine, Live Intranasal The therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Ritonavir.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The therapeutic efficacy of Varicella Zoster Vaccine (Live/attenuated) can be decreased when used in combination with Ritonavir.
Fulvestrant Injection Fulvestrant Injection The metabolism of Fulvestrant can be increased when combined with Ritonavir.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection The therapeutic efficacy of Insulin glulisine can be decreased when used in combination with Ritonavir.
Oxaliplatin Injection Oxaliplatin Injection Ritonavir may decrease the excretion rate of Oxaliplatin which could result in a higher serum level.
Posaconazole Posaconazole The serum concentration of Posaconazole can be increased when it is combined with Ritonavir.
Primaquine Primaquine The serum concentration of Primaquine can be increased when it is combined with Ritonavir.
Aliskiren Aliskiren The serum concentration of Aliskiren can be increased when it is combined with Ritonavir.
Darunavir Darunavir The serum concentration of Darunavir can be increased when it is combined with Ritonavir.
Pemetrexed Injection Pemetrexed Injection The metabolism of Pemetrexed can be increased when combined with Ritonavir.
Dimenhydrinate Dimenhydrinate The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Dimenhydrinate.
Lisdexamfetamine Lisdexamfetamine The metabolism of Lisdexamfetamine can be decreased when combined with Ritonavir.
Retapamulin Retapamulin The metabolism of Retapamulin can be decreased when combined with Ritonavir.
Vorinostat Vorinostat The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Vorinostat.
Sorafenib Sorafenib The serum concentration of Sorafenib can be increased when it is combined with Ritonavir.
Sunitinib Sunitinib The serum concentration of Sunitinib can be increased when it is combined with Ritonavir.
Dronabinol Dronabinol The serum concentration of Ritonavir can be increased when it is combined with Dronabinol.
Lapatinib Lapatinib The metabolism of Lapatinib can be decreased when combined with Ritonavir.
Levocetirizine Levocetirizine The serum concentration of Levocetirizine can be increased when it is combined with Ritonavir.
Dasatinib Dasatinib The metabolism of Dasatinib can be decreased when combined with Ritonavir.
Mexiletine Mexiletine The serum concentration of Mexiletine can be increased when it is combined with Ritonavir.
Armodafinil Armodafinil The metabolism of Ritonavir can be increased when combined with Armodafinil.
Ivermectin Ivermectin The serum concentration of Ivermectin can be increased when it is combined with Ritonavir.
Temsirolimus Temsirolimus The serum concentration of Temsirolimus can be increased when it is combined with Ritonavir.
Maraviroc Maraviroc The metabolism of Maraviroc can be decreased when combined with Ritonavir.
Nilotinib Nilotinib The metabolism of Nilotinib can be decreased when combined with Ritonavir.
Toremifene Toremifene The serum concentration of Toremifene can be increased when it is combined with Ritonavir.
Raltegravir Raltegravir The metabolism of Raltegravir can be increased when combined with Ritonavir.
Bexarotene Bexarotene The serum concentration of Bexarotene can be increased when it is combined with Ritonavir.
Budesonide Budesonide The serum concentration of Ritonavir can be increased when it is combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Ritonavir can be decreased when combined with Chloramphenicol.
Etravirine Etravirine The serum concentration of Etravirine can be decreased when it is combined with Ritonavir.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Arsenic trioxide.
Mitoxantrone Injection Mitoxantrone Injection Ritonavir may decrease the excretion rate of Mitoxantrone which could result in a higher serum level.
Desvenlafaxine Desvenlafaxine The serum concentration of Desvenlafaxine can be increased when it is combined with Ritonavir.
Cevimeline Cevimeline The serum concentration of Cevimeline can be increased when it is combined with Ritonavir.
Nebivolol Nebivolol The serum concentration of Nebivolol can be increased when it is combined with Ritonavir.
Tretinoin Tretinoin The serum concentration of Tretinoin can be increased when it is combined with Ritonavir.
Bendamustine Injection Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Ritonavir.
Flecainide Flecainide The serum concentration of Flecainide can be increased when it is combined with Ritonavir.
Certolizumab Injection Certolizumab Injection The metabolism of Ritonavir can be increased when combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The serum concentration of Ixabepilone can be increased when it is combined with Ritonavir.
Irinotecan Injection Irinotecan Injection The serum concentration of SN-38, an active metabolite of Irinotecan, can be increased when used in combination with Ritonavir.
Daptomycin Injection Daptomycin Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Daptomycin is combined with Ritonavir.
Estramustine Estramustine The serum concentration of Estramustine can be increased when it is combined with Ritonavir.
Praziquantel Praziquantel The serum concentration of Praziquantel can be increased when it is combined with Ritonavir.
Rufinamide Rufinamide The serum concentration of Rufinamide can be increased when it is combined with Ritonavir.
Silodosin Silodosin The serum concentration of Silodosin can be increased when it is combined with Ritonavir.
Midazolam Midazolam The serum concentration of Midazolam can be increased when it is combined with Ritonavir.
Naltrexone Injection Naltrexone Injection The metabolism of Naltrexone can be increased when combined with Ritonavir.
Eltrombopag Eltrombopag The metabolism of Eltrombopag can be decreased when combined with Ritonavir.
Milnacipran Milnacipran The serum concentration of Milnacipran can be increased when it is combined with Ritonavir.
Dexlansoprazole Dexlansoprazole The serum concentration of Dexlansoprazole can be increased when it is combined with Ritonavir.
Fesoterodine Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Ritonavir.
Degarelix Injection Degarelix Injection The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Degarelix.
Betaxolol Betaxolol The metabolism of Betaxolol can be decreased when combined with Ritonavir.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Ritonavir.
Prasugrel Prasugrel The serum concentration of Prasugrel can be increased when it is combined with Ritonavir.
Lacosamide Lacosamide The serum concentration of Lacosamide can be increased when it is combined with Ritonavir.
Everolimus Everolimus The serum concentration of Everolimus can be increased when it is combined with Ritonavir.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The serum concentration of Tolvaptan can be increased when it is combined with Ritonavir.
Dronedarone Dronedarone The serum concentration of Dronedarone can be increased when it is combined with Ritonavir.
Pralatrexate Injection Pralatrexate Injection Ritonavir may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection The serum concentration of Palonosetron can be increased when it is combined with Ritonavir.
Saxagliptin Saxagliptin The metabolism of Saxagliptin can be decreased when combined with Ritonavir.
Telavancin Injection Telavancin Injection The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Telavancin.
Romidepsin Injection Romidepsin Injection The serum concentration of Romidepsin can be increased when it is combined with Ritonavir.
Tapentadol Tapentadol The metabolism of Tapentadol can be decreased when combined with Ritonavir.
Topotecan Topotecan The serum concentration of Topotecan can be increased when it is combined with Ritonavir.
Golimumab Injection Golimumab Injection The metabolism of Ritonavir can be increased when combined with Golimumab.
Pazopanib Pazopanib The serum concentration of Pazopanib can be increased when it is combined with Ritonavir.
Asenapine Asenapine The serum concentration of Asenapine can be increased when it is combined with Ritonavir.
Pitavastatin Pitavastatin The serum concentration of Pitavastatin can be decreased when it is combined with Ritonavir.
Albendazole Albendazole The serum concentration of Albendazole can be increased when it is combined with Ritonavir.
Ulipristal Ulipristal The serum concentration of Ulipristal can be decreased when it is combined with Ritonavir.
Levonorgestrel Levonorgestrel The serum concentration of Levonorgestrel can be decreased when it is combined with Ritonavir.
Oxymorphone Oxymorphone The serum concentration of Oxymorphone can be increased when it is combined with Ritonavir.
Liraglutide Injection Liraglutide Injection The therapeutic efficacy of Liraglutide can be decreased when used in combination with Ritonavir.
Tocilizumab Injection Tocilizumab Injection The metabolism of Ritonavir can be increased when combined with Tocilizumab.
Eribulin Injection Eribulin Injection The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Eribulin.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Ritonavir.
Lurasidone Lurasidone The serum concentration of Lurasidone can be increased when it is combined with Ritonavir.
Acetaminophen Injection Acetaminophen Injection The serum concentration of Acetaminophen can be increased when it is combined with Ritonavir.
Vilazodone Vilazodone The metabolism of Vilazodone can be decreased when combined with Ritonavir.
Terbutaline Injection Terbutaline Injection The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Terbutaline.
Busulfan Injection Busulfan Injection The serum concentration of Busulfan can be increased when it is combined with Ritonavir.
Roflumilast Roflumilast The serum concentration of Roflumilast can be increased when it is combined with Ritonavir.
Linagliptin Linagliptin The serum concentration of Linagliptin can be increased when it is combined with Ritonavir.
Rilpivirine Rilpivirine The serum concentration of Rilpivirine can be increased when it is combined with Ritonavir.
Telaprevir Telaprevir The serum concentration of Glecaprevir can be increased when it is combined with Ritonavir.
Cyclophosphamide Injection Cyclophosphamide Injection The serum concentration of the active metabolites of Cyclophosphamide can be increased when Cyclophosphamide is used in combination with Ritonavir.
Abiraterone Abiraterone The serum concentration of Abiraterone can be increased when it is combined with Ritonavir.
Triptorelin Injection Triptorelin Injection The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Triptorelin.
Rivaroxaban Rivaroxaban The serum concentration of Rivaroxaban can be increased when it is combined with Ritonavir.
Ticagrelor Ticagrelor The serum concentration of Ticagrelor can be increased when it is combined with Ritonavir.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The serum concentration of Brentuximab vedotin can be increased when it is combined with Ritonavir.
Ruxolitinib Ruxolitinib The metabolism of Ruxolitinib can be decreased when combined with Ritonavir.
Vandetanib Vandetanib The serum concentration of Vandetanib can be increased when it is combined with Ritonavir.
Clobazam Clobazam The serum concentration of Clobazam can be increased when it is combined with Ritonavir.
Vemurafenib Vemurafenib The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Vemurafenib.
Vismodegib Vismodegib The serum concentration of Ritonavir can be increased when it is combined with Vismodegib.
Ivacaftor Ivacaftor The metabolism of Ivacaftor can be decreased when combined with Ritonavir.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Ritonavir.
Crizotinib Crizotinib The serum concentration of Crizotinib can be increased when it is combined with Ritonavir.
Cabergoline Cabergoline The serum concentration of Cabergoline can be increased when it is combined with Ritonavir.
Naloxone Injection Naloxone Injection The metabolism of Naloxone can be increased when combined with Ritonavir.
Ambrisentan Ambrisentan The serum concentration of Ambrisentan can be increased when it is combined with Ritonavir.
Ezogabine Ezogabine The serum concentration of Tiagabine can be increased when it is combined with Ritonavir.
Carfilzomib Injection Carfilzomib Injection The serum concentration of Carfilzomib can be increased when it is combined with Ritonavir.
Iloprost Iloprost The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Iloprost.
Enzalutamide Enzalutamide The serum concentration of Enzalutamide can be increased when it is combined with Ritonavir.
Mirabegron Mirabegron The serum concentration of Mirabegron can be increased when it is combined with Ritonavir.
Regorafenib Regorafenib The serum concentration of Ritonavir can be increased when it is combined with Regorafenib.
Bosutinib Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Ritonavir.
Corticotropin, Repository Injection Corticotropin, Repository Injection The serum concentration of Corticotropin can be increased when it is combined with Ritonavir.
Teriflunomide Teriflunomide Ritonavir may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Lorcaserin Lorcaserin The therapeutic efficacy of Mecasermin can be decreased when used in combination with Ritonavir.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Ritonavir.
Bedaquiline Bedaquiline The metabolism of Bedaquiline can be decreased when combined with Ritonavir.
Tofacitinib Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Ritonavir.
Alogliptin Alogliptin The serum concentration of Alogliptin can be increased when it is combined with Ritonavir.
Ponatinib Ponatinib The metabolism of Ponatinib can be decreased when combined with Ritonavir.
Pomalidomide Pomalidomide The serum concentration of Pomalidomide can be increased when it is combined with Ritonavir.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Ritonavir.
Apixaban Apixaban The serum concentration of Apixaban can be increased when it is combined with Ritonavir.
Canagliflozin Canagliflozin The metabolism of Canagliflozin can be increased when combined with Ritonavir.
Dabrafenib Dabrafenib The serum concentration of Dabrafenib can be increased when it is combined with Ritonavir.
Ospemifene Ospemifene The serum concentration of Ospemifene can be increased when it is combined with Ritonavir.
Dolutegravir Dolutegravir The metabolism of Dolutegravir can be increased when combined with Ritonavir.
Afatinib Afatinib The serum concentration of Afatinib can be increased when it is combined with Ritonavir.
Levomilnacipran Levomilnacipran The serum concentration of Levomilnacipran can be increased when it is combined with Ritonavir.
Vortioxetine Vortioxetine The serum concentration of Vortioxetine can be increased when it is combined with Ritonavir.
Perampanel Perampanel The serum concentration of Perampanel can be increased when it is combined with Ritonavir.
Ibrutinib Ibrutinib The serum concentration of Ibrutinib can be increased when it is combined with Ritonavir.
Lomitapide Lomitapide The serum concentration of Lomitapide can be increased when it is combined with Ritonavir.
Avanafil Avanafil The serum concentration of Avanafil can be increased when it is combined with Ritonavir.
Ketorolac Injection Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Ritonavir.
Simeprevir Simeprevir The serum concentration of Simeprevir can be increased when it is combined with Ritonavir.
Sofosbuvir Sofosbuvir Ritonavir may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin The serum concentration of Dapagliflozin can be increased when it is combined with Ritonavir.
Apremilast Apremilast The serum concentration of Apremilast can be increased when it is combined with Ritonavir.
Ceritinib Ceritinib The metabolism of Ceritinib can be decreased when combined with Ritonavir.
Siltuximab Injection Siltuximab Injection The metabolism of Ritonavir can be increased when combined with Siltuximab.
Albiglutide Injection Albiglutide Injection The therapeutic efficacy of Albiglutide can be decreased when used in combination with Ritonavir.
Eslicarbazepine Eslicarbazepine The metabolism of Eslicarbazepine can be increased when combined with Ritonavir.
Belinostat Injection Belinostat Injection The metabolism of Belinostat can be increased when combined with Ritonavir.
Idelalisib Idelalisib The serum concentration of Idelalisib can be increased when it is combined with Ritonavir.
Testosterone Injection Testosterone Injection The serum concentration of Ritonavir can be increased when it is combined with Testosterone.
Oritavancin Injection Oritavancin Injection The metabolism of Ritonavir can be decreased when combined with Oritavancin.
Empagliflozin Empagliflozin The therapeutic efficacy of Empagliflozin can be decreased when used in combination with Ritonavir.
Vorapaxar Vorapaxar The serum concentration of Vorapaxar can be increased when it is combined with Ritonavir.
Hydrocodone Hydrocodone The metabolism of Hydrocodone can be decreased when combined with Ritonavir.
Suvorexant Suvorexant The serum concentration of Suvorexant can be increased when it is combined with Ritonavir.
Dulaglutide Injection Dulaglutide Injection The therapeutic efficacy of Dulaglutide can be decreased when used in combination with Ritonavir.
Edoxaban Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Ritonavir.
Olaparib Olaparib The metabolism of Olaparib can be decreased when combined with Ritonavir.
Caspofungin Injection Caspofungin Injection The excretion of Caspofungin can be decreased when combined with Ritonavir.
Methamphetamine Methamphetamine The serum concentration of Metamfetamine can be increased when it is combined with Ritonavir.
Tasimelteon Tasimelteon The serum concentration of Tasimelteon can be increased when it is combined with Ritonavir.
Riociguat Riociguat The serum concentration of Riociguat can be increased when it is combined with Ritonavir.
Pirfenidone Pirfenidone The metabolism of Pirfenidone can be increased when combined with Ritonavir.
Nintedanib Nintedanib The serum concentration of Nintedanib can be increased when it is combined with Ritonavir.
Secukinumab Injection Secukinumab Injection The metabolism of Ritonavir can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The serum concentration of Risperidone can be increased when it is combined with Ritonavir.
Palbociclib Palbociclib The metabolism of Palbociclib can be decreased when combined with Ritonavir.
Insulin Human Inhalation Insulin Human Inhalation The therapeutic efficacy of Insulin human can be decreased when used in combination with Ritonavir.
Lenvatinib Lenvatinib The serum concentration of Lenvatinib can be increased when it is combined with Ritonavir.
Naloxegol Naloxegol The serum concentration of Naloxegol can be increased when it is combined with Ritonavir.
Panobinostat Panobinostat The metabolism of Panobinostat can be decreased when combined with Ritonavir.
Haloperidol Injection Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Ritonavir.
Deoxycholic Acid Injection Deoxycholic Acid Injection Deoxycholic acid may increase the excretion rate of Ritonavir which could result in a lower serum level and potentially a reduction in efficacy.
Ivabradine Ivabradine The serum concentration of Ivabradine can be increased when it is combined with Ritonavir.
Isavuconazonium Injection Isavuconazonium Injection The serum concentration of Isavuconazonium can be increased when it is combined with Ritonavir.
Macitentan Macitentan The serum concentration of Macitentan can be increased when it is combined with Ritonavir.
Sonidegib Sonidegib The serum concentration of Sonidegib can be increased when it is combined with Ritonavir.
Flibanserin Flibanserin The metabolism of Flibanserin can be decreased when combined with Ritonavir.
Rolapitant Rolapitant The serum concentration of Rolapitant can be increased when it is combined with Ritonavir.
Prednisolone Prednisolone The serum concentration of Prednisolone can be increased when it is combined with Ritonavir.
Daclatasvir Daclatasvir The metabolism of Daclatasvir can be decreased when combined with Ritonavir.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Ritonavir.
Ziprasidone Injection Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Ziprasidone.
Cariprazine Cariprazine The serum concentration of Cariprazine can be increased when it is combined with Ritonavir.
Eluxadoline Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Ritonavir.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection The therapeutic efficacy of Insulin degludec can be decreased when used in combination with Ritonavir.
Cobimetinib Cobimetinib The serum concentration of Cobimetinib can be increased when it is combined with Ritonavir.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Ritonavir.
Osimertinib Osimertinib The metabolism of Osimertinib can be decreased when combined with Ritonavir.
Alectinib Alectinib The metabolism of Ritonavir can be decreased when combined with Alectinib.
Ixazomib Ixazomib The serum concentration of Ixazomib can be increased when it is combined with Ritonavir.
Rifapentine Rifapentine The serum concentration of Rifapentine can be increased when it is combined with Ritonavir.
Lesinurad Lesinurad The metabolism of Lesinurad can be increased when combined with Ritonavir.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Amphotericin B.
Dexamethasone Injection Dexamethasone Injection The serum concentration of Dexamethasone can be increased when it is combined with Ritonavir.
Brivaracetam Injection Brivaracetam Injection The serum concentration of Brivaracetam can be increased when it is combined with Ritonavir.
Venetoclax Venetoclax The serum concentration of Venetoclax can be increased when it is combined with Ritonavir.
Cobicistat Cobicistat The serum concentration of Cobicistat can be increased when it is combined with Ritonavir.
Selexipag Selexipag The serum concentration of Selexipag can be increased when it is combined with Ritonavir.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Ritonavir.
Furosemide Injection Furosemide Injection The metabolism of Furosemide can be increased when combined with Ritonavir.
Rucaparib Rucaparib The serum concentration of Rucaparib can be increased when it is combined with Ritonavir.
Lixisenatide Injection Lixisenatide Injection The therapeutic efficacy of Lixisenatide can be decreased when used in combination with Ritonavir.
Ribociclib Ribociclib The metabolism of Ribociclib can be decreased when combined with Ritonavir.
Brigatinib Brigatinib The metabolism of Brigatinib can be decreased when combined with Ritonavir.
Doxepin (Insomnia) Doxepin (Insomnia) The serum concentration of Doxepin can be increased when it is combined with Ritonavir.
Deutetrabenazine Deutetrabenazine The serum concentration of Deutetrabenazine can be increased when it is combined with Ritonavir.
Valbenazine Valbenazine The serum concentration of Valbenazine can be increased when it is combined with Ritonavir.
Deflazacort Deflazacort The serum concentration of Deflazacort can be increased when it is combined with Ritonavir.
Safinamide Safinamide The serum concentration of Ritonavir can be increased when it is combined with Safinamide.
Midostaurin Midostaurin The serum concentration of Ritonavir can be increased when it is combined with Midostaurin.
Neratinib Neratinib The serum concentration of Neratinib can be increased when it is combined with Ritonavir.
Enasidenib Enasidenib The serum concentration of Enasidenib can be increased when it is combined with Ritonavir.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The serum concentration of Inotuzumab ozogamicin can be increased when it is combined with Ritonavir.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The serum concentration of Fosaprepitant can be increased when it is combined with Ritonavir.
Copanlisib Injection Copanlisib Injection The serum concentration of Copanlisib can be increased when it is combined with Ritonavir.
Delafloxacin Delafloxacin The metabolism of Delafloxacin can be increased when combined with Ritonavir.
Abemaciclib Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Ritonavir.
Betrixaban Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Ritonavir.
Acalabrutinib Acalabrutinib The serum concentration of Ritonavir can be increased when it is combined with Acalabrutinib.
Letermovir Letermovir The metabolism of Ritonavir can be decreased when combined with Letermovir.
Semaglutide Injection Semaglutide Injection The therapeutic efficacy of Semaglutide can be decreased when used in combination with Ritonavir.
Tetrabenazine Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Ritonavir.
Ertugliflozin Ertugliflozin The serum concentration of Ertugliflozin can be increased when it is combined with Ritonavir.
Buprenorphine Injection Buprenorphine Injection The serum concentration of Buprenorphine can be increased when it is combined with Ritonavir.
Apalutamide Apalutamide The serum concentration of Apalutamide can be decreased when it is combined with Ritonavir.
Penicillamine Penicillamine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Penicillamine.
Fostamatinib Fostamatinib The serum concentration of R406, an active metabolite of Ritonavir, can be increased when used in combination with Fostamatinib.
Avatrombopag Avatrombopag The serum concentration of Avatrombopag can be increased when it is combined with Ritonavir.
Baricitinib Baricitinib The serum concentration of Baricitinib can be increased when it is combined with Ritonavir.
Sodium Zirconium Cyclosilicate Sodium Zirconium Cyclosilicate Sodium zirconium cyclosilicate can cause a decrease in the absorption of Ritonavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lofexidine Lofexidine The metabolism of Lofexidine can be decreased when combined with Ritonavir.
Eliglustat Eliglustat The metabolism of Eliglustat can be decreased when combined with Ritonavir.
Encorafenib Encorafenib The serum concentration of Encorafenib can be increased when it is combined with Ritonavir.
Binimetinib Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Ritonavir.
Ivosidenib Ivosidenib The serum concentration of Ivosidenib can be increased when it is combined with Ritonavir.
Lusutrombopag Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Ritonavir.
Elagolix Elagolix The serum concentration of Elagolix can be increased when it is combined with Ritonavir.
Eravacycline Injection Eravacycline Injection The serum concentration of Eravacycline can be increased when it is combined with Ritonavir.
Doravirine Doravirine The serum concentration of Doravirine can be increased when it is combined with Ritonavir.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Ritonavir.
Cannabidiol Cannabidiol The serum concentration of Cannabidiol can be increased when it is combined with Ritonavir.
Dacomitinib Dacomitinib The serum concentration of Dacomitinib can be increased when it is combined with Ritonavir.
Duvelisib Duvelisib The metabolism of Duvelisib can be decreased when combined with Ritonavir.
Omadacycline Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Ritonavir.
Stiripentol Stiripentol The metabolism of Ritonavir can be decreased when combined with Stiripentol.
Talazoparib Talazoparib The serum concentration of Talazoparib can be increased when it is combined with Ritonavir.
Gilteritinib Gilteritinib The serum concentration of Gilteritinib can be increased when it is combined with Ritonavir.
Glasdegib Glasdegib The serum concentration of Glasdegib can be increased when it is combined with Ritonavir.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Ritonavir.
Larotrectinib Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Ritonavir.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The serum concentration of Ritonavir can be increased when it is combined with Paclitaxel.
Rifamycin Rifamycin The serum concentration of Rifamycin can be increased when it is combined with Ritonavir.
Prucalopride Prucalopride The serum concentration of Prucalopride can be increased when it is combined with Ritonavir.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Ritonavir can be increased when combined with Emapalumab.
Siponimod Siponimod The risk or severity of adverse effects can be increased when Ritonavir is combined with Siponimod.
Acyclovir Ophthalmic Acyclovir Ophthalmic The metabolism of Acyclovir can be increased when combined with Ritonavir.
Erdafitinib Erdafitinib The serum concentration of Erdafitinib can be increased when it is combined with Ritonavir.
Esomeprazole Injection Esomeprazole Injection The serum concentration of Esomeprazole can be increased when it is combined with Ritonavir.
Alpelisib Alpelisib The serum concentration of Alpelisib can be increased when it is combined with Ritonavir.
Cladribine Cladribine Ritonavir may decrease the excretion rate of Cladribine which could result in a higher serum level.
Polatuzumab vedotin-piiq Injection Polatuzumab vedotin-piiq Injection The risk or severity of adverse effects can be increased when Ritonavir is combined with Polatuzumab vedotin.
Selinexor Selinexor The serum concentration of Selinexor can be increased when it is combined with Ritonavir.
Darolutamide Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Ritonavir.
Triclabendazole Triclabendazole The serum concentration of Triclabendazole can be increased when it is combined with Ritonavir.
Entrectinib Entrectinib The metabolism of Entrectinib can be decreased when combined with Ritonavir.
Pexidartinib Pexidartinib The metabolism of Pexidartinib can be decreased when combined with Ritonavir.
Upadacitinib Upadacitinib The serum concentration of Upadacitinib can be increased when it is combined with Ritonavir.
Istradefylline Istradefylline The serum concentration of Istradefylline can be increased when it is combined with Ritonavir.
Pitolisant Pitolisant The serum concentration of Ritonavir can be decreased when it is combined with Pitolisant.
Pretomanid Pretomanid The serum concentration of Pretomanid can be increased when it is combined with Ritonavir.
Fedratinib Fedratinib The serum concentration of Fedratinib can be increased when it is combined with Ritonavir.
Lefamulin Lefamulin Ritonavir may increase the QTc-prolonging activities of Lefamulin.
Phenytoin Injection Phenytoin Injection The serum concentration of Ritonavir can be decreased when it is combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The serum concentration of Ritonavir can be decreased when it is combined with Fosphenytoin.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Ritonavir.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Ritonavir.
Voxelotor Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Ritonavir.
Avapritinib Avapritinib The serum concentration of Avapritinib can be increased when it is combined with Ritonavir.
Lumateperone Lumateperone The serum concentration of Lumateperone can be increased when it is combined with Ritonavir.
Lasmiditan Lasmiditan The serum concentration of Lasmiditan can be increased when it is combined with Ritonavir.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Ritonavir.
Tazemetostat Tazemetostat The serum concentration of Tazemetostat can be increased when it is combined with Ritonavir.
Bempedoic Acid Bempedoic Acid The excretion of Bempedoic acid can be decreased when combined with Ritonavir.
Cenobamate Cenobamate The serum concentration of Cenobamate can be decreased when it is combined with Ritonavir.
Pemigatinib Pemigatinib The metabolism of Pemigatinib can be decreased when combined with Ritonavir.
Ozanimod Ozanimod The metabolism of Ozanimod can be decreased when combined with Ritonavir.
Selumetinib Selumetinib The serum concentration of Selumetinib can be increased when it is combined with Ritonavir.
Rimegepant Rimegepant The metabolism of Rimegepant can be decreased when combined with Ritonavir.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Ritonavir.
Remdesivir Injection Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Ritonavir.
Sacituzumab govitecan-hziy Injection Sacituzumab govitecan-hziy Injection The serum concentration of Sacituzumab govitecan can be decreased when it is combined with Ritonavir.
Ripretinib Ripretinib The serum concentration of Ripretinib can be increased when it is combined with Ritonavir.
Selpercatinib Selpercatinib The serum concentration of Selpercatinib can be increased when it is combined with Ritonavir.
Capmatinib Capmatinib The serum concentration of Capmatinib can be increased when it is combined with Ritonavir.
Lemborexant Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Ritonavir.
Fenfluramine Fenfluramine The metabolism of Ritonavir can be decreased when combined with Fenfluramine.
Lurbinectedin Injection Lurbinectedin Injection The serum concentration of Lurbinectedin can be increased when it is combined with Ritonavir.
Octreotide Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Ritonavir.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Ritonavir.
Pralsetinib Pralsetinib The serum concentration of Ritonavir can be increased when it is combined with Pralsetinib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Ritonavir can be decreased when it is combined with Satralizumab.
Relugolix Relugolix The serum concentration of Relugolix can be increased when it is combined with Ritonavir.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The serum concentration of Drospirenone can be decreased when it is combined with Ritonavir.
Vitamin E (Alpha-Tocopherol) Vitamin E (Alpha-Tocopherol) The serum concentration of Vitamin E can be increased when it is combined with Ritonavir.
Theophylline Theophylline The serum concentration of Theophylline can be decreased when it is combined with Ritonavir.
Indomethacin Indomethacin The metabolism of Indomethacin can be increased when combined with Ritonavir.
Mefenamic Acid Mefenamic Acid The metabolism of Mefenamic acid can be increased when combined with Ritonavir.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Ritonavir.
Trazodone Trazodone The serum concentration of Ritonavir can be increased when it is combined with Trazodone.
Isotretinoin Isotretinoin The serum concentration of Isotretinoin can be increased when it is combined with Ritonavir.
Sodium Bicarbonate Sodium Bicarbonate Sodium bicarbonate can cause a decrease in the absorption of Ritonavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Hydroxyurea Hydroxyurea The metabolism of Ritonavir can be decreased when combined with Hydroxyurea.
Phenobarbital Phenobarbital The metabolism of Ritonavir can be increased when combined with Phenobarbital.
Methotrexate Injection Methotrexate Injection The serum concentration of Methotrexate can be increased when it is combined with Ritonavir.
Primidone Primidone The metabolism of Primidone can be decreased when combined with Ritonavir.
Methsuximide Methsuximide The metabolism of Methsuximide can be decreased when combined with Ritonavir.
Chlorpromazine Chlorpromazine The serum concentration of Chlorpromazine can be increased when it is combined with Ritonavir.
Diazepam Diazepam The serum concentration of Diazepam can be increased when it is combined with Ritonavir.
Flurazepam Flurazepam The serum concentration of Flurazepam can be increased when it is combined with Ritonavir.
Clorazepate Clorazepate The serum concentration of Clorazepic acid can be increased when it is combined with Ritonavir.
Lorazepam Lorazepam The serum concentration of Lorazepam can be increased when it is combined with Ritonavir.
Carmustine Carmustine The metabolism of Carmustine can be increased when combined with Ritonavir.
Amantadine Amantadine The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Amantadine.
Codeine Codeine The serum concentration of Codeine can be increased when it is combined with Ritonavir.
Bromocriptine Bromocriptine The serum concentration of Bromocriptine can be increased when it is combined with Ritonavir.
Tranylcypromine Tranylcypromine The metabolism of Tranylcypromine can be decreased when combined with Ritonavir.
Phenelzine Phenelzine The metabolism of Ritonavir can be decreased when combined with Phenelzine.
Procarbazine Procarbazine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Procarbazine.
Ergoloid Mesylates Ergoloid Mesylates The serum concentration of Ergoloid mesylate can be increased when it is combined with Ritonavir.
Tetracycline Tetracycline The serum concentration of Tetracycline can be increased when it is combined with Ritonavir.
Minocycline Minocycline The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Minocycline.
Prochlorperazine Prochlorperazine The serum concentration of Prochlorperazine can be increased when it is combined with Ritonavir.
Thioridazine Thioridazine The metabolism of Ritonavir can be decreased when combined with Thioridazine.
Trifluoperazine Trifluoperazine The metabolism of Trifluoperazine can be increased when combined with Ritonavir.
Dapsone Dapsone The serum concentration of Dapsone can be increased when it is combined with Ritonavir.
Sulfadiazine Sulfadiazine The serum concentration of Sulfadiazine can be increased when it is combined with Ritonavir.
Oxycodone Oxycodone The serum concentration of Oxycodone can be increased when it is combined with Ritonavir.
Methadone Methadone The serum concentration of Methadone can be decreased when it is combined with Ritonavir.
Oxybutynin Oxybutynin The serum concentration of Oxybutynin can be increased when it is combined with Ritonavir.
Benztropine Benztropine The metabolism of Benzatropine can be decreased when combined with Ritonavir.
Maprotiline Maprotiline The metabolism of Maprotiline can be decreased when combined with Ritonavir.
Ibuprofen Ibuprofen The serum concentration of Ibuprofen can be increased when it is combined with Ritonavir.
Orphenadrine Orphenadrine The serum concentration of Orphenadrine can be increased when it is combined with Ritonavir.
Perphenazine Perphenazine The metabolism of Perphenazine can be decreased when combined with Ritonavir.
Azathioprine Azathioprine The metabolism of Azathioprine can be increased when combined with Ritonavir.
Fluphenazine Fluphenazine The metabolism of Ritonavir can be decreased when combined with Fluphenazine.
Phentermine Phentermine The serum concentration of Phentermine can be increased when it is combined with Ritonavir.
Amoxapine Amoxapine The metabolism of Amoxapine can be decreased when combined with Ritonavir.
Sulfasalazine Sulfasalazine Ritonavir may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Hydrocortisone Hydrocortisone The serum concentration of Hydrocortisone can be increased when it is combined with Ritonavir.
Doxorubicin Doxorubicin The serum concentration of Doxorubicin can be increased when it is combined with Ritonavir.
Cytarabine Cytarabine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Cytarabine.
Dactinomycin Dactinomycin The serum concentration of Dactinomycin can be increased when it is combined with Ritonavir.
Carbamazepine Carbamazepine The serum concentration of Carbamazepine can be decreased when it is combined with Ritonavir.
Methyldopa Methyldopa The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Methyldopa.
Clonidine Clonidine The serum concentration of Clonidine can be increased when it is combined with Ritonavir.
Prazosin Prazosin Ritonavir may decrease the excretion rate of Prazosin which could result in a higher serum level.
Cimetidine Cimetidine The metabolism of Ritonavir can be decreased when combined with Cimetidine.
Warfarin Warfarin The serum concentration of Warfarin can be decreased when it is combined with Ritonavir.
Clonazepam Clonazepam The serum concentration of Clonazepam can be increased when it is combined with Ritonavir.
Loperamide Loperamide The serum concentration of Loperamide can be increased when it is combined with Ritonavir.
Promethazine Promethazine The metabolism of Promethazine can be decreased when combined with Ritonavir.
Daunorubicin Daunorubicin Ritonavir may decrease the excretion rate of Daunorubicin which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Ritonavir may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Digoxin Digoxin The bioavailability of Digoxin can be increased when combined with Ritonavir.
Chloroquine Chloroquine The serum concentration of Chloroquine can be increased when it is combined with Ritonavir.
Quinine Quinine The serum concentration of Quinine can be increased when it is combined with Ritonavir.
Ethosuximide Ethosuximide The serum concentration of Ethosuximide can be increased when it is combined with Ritonavir.
Calcitriol Calcitriol The serum concentration of Calcitriol can be increased when it is combined with Ritonavir.
Triamterene Triamterene The metabolism of Triamterene can be increased when combined with Ritonavir.
Sulfinpyrazone Sulfinpyrazone The serum concentration of Sulfinpyrazone can be increased when it is combined with Ritonavir.
Isosorbide Isosorbide The serum concentration of Isosorbide can be decreased when it is combined with Ritonavir.
Clindamycin Injection Clindamycin Injection The serum concentration of Clindamycin can be increased when it is combined with Ritonavir.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Ritonavir.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Ritonavir.
Imipramine Imipramine The serum concentration of Imipramine can be increased when it is combined with Ritonavir.
Quinidine Quinidine The serum concentration of Quinidine can be increased when it is combined with Ritonavir.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Ritonavir.
Isoniazid Isoniazid The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Isoniazid.
Rifampin Rifampin The serum concentration of Ritonavir can be decreased when it is combined with Rifampicin.
Disopyramide Disopyramide The serum concentration of Disopyramide can be increased when it is combined with Ritonavir.
Valproic Acid Valproic Acid The metabolism of Valproic acid can be increased when combined with Ritonavir.
Tamoxifen Tamoxifen The serum concentration of Tamoxifen can be increased when it is combined with Ritonavir.
Levothyroxine Levothyroxine The metabolism of Levothyroxine can be increased when combined with Ritonavir.
Liothyronine Liothyronine The metabolism of Liothyronine can be increased when combined with Ritonavir.
Methimazole Methimazole The metabolism of Ritonavir can be decreased when combined with Methimazole.
Propylthiouracil Propylthiouracil The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Propylthiouracil.
Chlorpropamide Chlorpropamide The therapeutic efficacy of Chlorpropamide can be decreased when used in combination with Ritonavir.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Ritonavir.
Tolazamide Tolazamide The therapeutic efficacy of Tolazamide can be decreased when used in combination with Ritonavir.
Dextromethorphan Dextromethorphan The serum concentration of Dextromethorphan can be increased when it is combined with Ritonavir.
Dinoprostone Dinoprostone The excretion of Dinoprostone can be decreased when combined with Ritonavir.
Cyclobenzaprine Cyclobenzaprine The serum concentration of Cyclobenzaprine can be increased when it is combined with Ritonavir.
Niacin Niacin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Niacin.
Baclofen Baclofen The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Ritonavir.
Doxylamine Doxylamine The risk or severity of QTc prolongation can be increased when Doxylamine is combined with Ritonavir.
Cyproheptadine Cyproheptadine The risk or severity of QTc prolongation can be increased when Cyproheptadine is combined with Ritonavir.
Clemastine Clemastine The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Clemastine.
Chlorpheniramine Chlorpheniramine The serum concentration of Chlorpheniramine can be increased when it is combined with Ritonavir.
Brompheniramine Brompheniramine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Ritonavir.
Meclizine Meclizine The metabolism of Meclizine can be decreased when combined with Ritonavir.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Hydrochlorothiazide.
Chlorzoxazone Chlorzoxazone The serum concentration of Chlorzoxazone can be increased when it is combined with Ritonavir.
Carisoprodol Carisoprodol The metabolism of Carisoprodol can be decreased when combined with Ritonavir.
Folic Acid Folic Acid Ritonavir may decrease the excretion rate of Folic acid which could result in a higher serum level.
Disulfiram Disulfiram The risk or severity of adverse effects can be increased when Ritonavir is combined with Disulfiram.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The serum concentration of Propranolol can be increased when it is combined with Ritonavir.
Minoxidil Minoxidil The metabolism of Minoxidil can be increased when combined with Ritonavir.
Nortriptyline Nortriptyline The serum concentration of Nortriptyline can be increased when it is combined with Ritonavir.
Spironolactone Spironolactone Spironolactone may decrease the excretion rate of Ritonavir which could result in a higher serum level.
Amphotericin B Injection Amphotericin B Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Amphotericin B.
Nadolol Nadolol The metabolism of Nadolol can be decreased when combined with Ritonavir.
Allopurinol Allopurinol Ritonavir may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Oxytocin Injection Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Ritonavir.
Clomiphene Clomiphene The serum concentration of Clomifene can be increased when it is combined with Ritonavir.
Papaverine Papaverine The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Papaverine.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Ritonavir.
Colchicine Colchicine The serum concentration of Colchicine can be increased when it is combined with Ritonavir.
Cefaclor Cefaclor Ritonavir may decrease the excretion rate of Cefaclor which could result in a higher serum level.
Cephalexin Cephalexin The serum concentration of Cephalexin can be increased when it is combined with Ritonavir.
Dacarbazine Dacarbazine The metabolism of Dacarbazine can be increased when combined with Ritonavir.
Bacillus Calmette-Guerin (BCG) Vaccine Bacillus Calmette-Guerin (BCG) Vaccine The therapeutic efficacy of Bacillus calmette-guerin substrain tice live antigen can be decreased when used in combination with Ritonavir.
Ketoconazole Ketoconazole The bioavailability of Ketoconazole can be increased when combined with Ritonavir.
Thiotepa Injection Thiotepa Injection The serum concentration of Thiotepa can be increased when it is combined with Ritonavir.
Vincristine Injection Vincristine Injection The serum concentration of Vincristine can be increased when it is combined with Ritonavir.
Captopril Captopril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Captopril.
Dipyridamole Dipyridamole The serum concentration of Dipyridamole can be increased when it is combined with Ritonavir.
Vinblastine Vinblastine The serum concentration of Vinblastine can be increased when it is combined with Ritonavir.
Metoprolol Metoprolol The serum concentration of Metoprolol can be increased when it is combined with Ritonavir.
Hydroxyzine Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Ritonavir.
Thiothixene Thiothixene The metabolism of Thiothixene can be increased when combined with Ritonavir.
Aspirin Aspirin The metabolism of Acetylsalicylic acid can be increased when combined with Ritonavir.
Alprazolam Alprazolam The metabolism of Alprazolam can be decreased when combined with Ritonavir.
Triazolam Triazolam The serum concentration of Triazolam can be increased when it is combined with Ritonavir.
Hyoscyamine Hyoscyamine The risk or severity of QTc prolongation can be increased when Hyoscyamine is combined with Ritonavir.
Trimethoprim Trimethoprim The serum concentration of Trimethoprim can be increased when it is combined with Ritonavir.
Diltiazem Diltiazem The serum concentration of Ritonavir can be increased when it is combined with Diltiazem.
Nifedipine Nifedipine The serum concentration of Nifedipine can be increased when it is combined with Ritonavir.
Timolol Timolol The metabolism of Timolol can be decreased when combined with Ritonavir.
Verapamil Verapamil The serum concentration of Verapamil can be increased when it is combined with Ritonavir.
Atenolol Atenolol The metabolism of Atenolol can be decreased when combined with Ritonavir.
Pindolol Pindolol The metabolism of Pindolol can be decreased when combined with Ritonavir.
Piroxicam Piroxicam The metabolism of Piroxicam can be decreased when combined with Ritonavir.
Bumetanide Bumetanide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Bumetanide.
Etoposide Etoposide The serum concentration of Etoposide can be increased when it is combined with Ritonavir.
Glyburide Glyburide The serum concentration of Ritonavir can be increased when it is combined with Glyburide.
Glipizide Glipizide The metabolism of Glipizide can be increased when combined with Ritonavir.
Indapamide Indapamide The serum concentration of Indapamide can be increased when it is combined with Ritonavir.
Pentoxifylline Pentoxifylline The serum concentration of Pentoxifylline can be increased when it is combined with Ritonavir.
Pentamidine Injection Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Ritonavir.
Labetalol Labetalol The metabolism of Ritonavir can be decreased when combined with Labetalol.
Leuprolide Injection Leuprolide Injection The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Leuprolide.
Gemfibrozil Gemfibrozil The serum concentration of Gemfibrozil can be increased when it is combined with Ritonavir.
Guanabenz Guanabenz The metabolism of Guanabenz can be increased when combined with Ritonavir.
Ketoprofen Ketoprofen The metabolism of Ketoprofen can be increased when combined with Ritonavir.
Pimozide Pimozide The serum concentration of Pimozide can be increased when it is combined with Ritonavir.
Enalapril Enalapril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Enalapril.
Flurbiprofen Flurbiprofen The metabolism of Flurbiprofen can be increased when combined with Ritonavir.
Amiodarone Amiodarone The metabolism of Amiodarone can be decreased when combined with Ritonavir.
Buspirone Buspirone The serum concentration of Buspirone can be increased when it is combined with Ritonavir.
Lovastatin Lovastatin The serum concentration of Lovastatin can be increased when it is combined with Ritonavir.
Ciprofloxacin Ciprofloxacin The metabolism of Ritonavir can be decreased when combined with Ciprofloxacin.
Diclofenac Diclofenac The serum concentration of Diclofenac can be increased when it is combined with Ritonavir.
Fluoxetine Fluoxetine The serum concentration of Fluoxetine can be increased when it is combined with Ritonavir.
Nimodipine Nimodipine The serum concentration of Nimodipine can be increased when it is combined with Ritonavir.
Clozapine Clozapine The serum concentration of Clozapine can be increased when it is combined with Ritonavir.
Estazolam Estazolam The serum concentration of Estazolam can be increased when it is combined with Ritonavir.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Ritonavir.
Ofloxacin Ofloxacin The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Ofloxacin.
Clarithromycin Clarithromycin The serum concentration of Clarithromycin can be increased when it is combined with Ritonavir.
Etodolac Etodolac The metabolism of Etodolac can be increased when combined with Ritonavir.
Felodipine Felodipine The serum concentration of Felodipine can be increased when it is combined with Ritonavir.
Nabumetone Nabumetone The metabolism of Nabumetone can be increased when combined with Ritonavir.
Pravastatin Pravastatin Ritonavir may increase the myopathic rhabdomyolysis activities of Pravastatin.
Simvastatin Simvastatin The metabolism of Simvastatin can be decreased when combined with Ritonavir.
Amlodipine Amlodipine The metabolism of Amlodipine can be decreased when combined with Ritonavir.
Teniposide Injection Teniposide Injection The serum concentration of Teniposide can be increased when it is combined with Ritonavir.
Itraconazole Itraconazole The serum concentration of Itraconazole can be increased when it is combined with Ritonavir.
Atovaquone Atovaquone The serum concentration of Atovaquone can be decreased when it is combined with Ritonavir.
Rifabutin Rifabutin The serum concentration of the active metabolites of Rifabutin can be increased when Rifabutin is used in combination with Ritonavir.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Ritonavir.
Bisoprolol Bisoprolol The serum concentration of Bisoprolol can be increased when it is combined with Ritonavir.
Zolpidem Zolpidem The serum concentration of Zolpidem can be increased when it is combined with Ritonavir.
Doxazosin Doxazosin The metabolism of Doxazosin can be decreased when combined with Ritonavir.
Isradipine Isradipine The serum concentration of Ritonavir can be increased when it is combined with Isradipine.
Omeprazole Omeprazole The serum concentration of Omeprazole can be increased when it is combined with Ritonavir.
Cisapride Cisapride The serum concentration of Cisapride can be increased when it is combined with Ritonavir.
Fluvastatin Fluvastatin The serum concentration of Fluvastatin can be increased when it is combined with Ritonavir.
Venlafaxine Venlafaxine The serum concentration of Venlafaxine can be increased when it is combined with Ritonavir.
Nizatidine Nizatidine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Nizatidine.
Stavudine Stavudine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Stavudine.
Famciclovir Famciclovir The serum concentration of Famciclovir can be increased when it is combined with Ritonavir.
Fluvoxamine Fluvoxamine The serum concentration of Fluvoxamine can be increased when it is combined with Ritonavir.
Nefazodone Nefazodone The serum concentration of Ritonavir can be increased when it is combined with Nefazodone.
Lamotrigine Lamotrigine The serum concentration of Lamotrigine can be decreased when it is combined with Ritonavir.
Losartan Losartan The serum concentration of Losartan can be increased when it is combined with Ritonavir.
Tramadol Tramadol The serum concentration of Tramadol can be increased when it is combined with Ritonavir.
Vinorelbine Injection Vinorelbine Injection The serum concentration of Ritonavir can be increased when it is combined with Vinorelbine.
Moexipril Moexipril The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Moexipril.
Lansoprazole Lansoprazole The serum concentration of Lansoprazole can be increased when it is combined with Ritonavir.
Ifosfamide Injection Ifosfamide Injection The serum concentration of Ifosfamide can be increased when it is combined with Ritonavir.
Nicardipine Nicardipine The serum concentration of Nicardipine can be increased when it is combined with Ritonavir.
Bupropion Bupropion The metabolism of Bupropion can be increased when combined with Ritonavir.
Ticlopidine Ticlopidine The serum concentration of Ticlopidine can be increased when it is combined with Ritonavir.
Saquinavir Saquinavir The serum concentration of Saquinavir can be increased when it is combined with Ritonavir.
Metformin Metformin The therapeutic efficacy of Metformin can be decreased when used in combination with Ritonavir.
Nisoldipine Nisoldipine The serum concentration of Nisoldipine can be increased when it is combined with Ritonavir.
Lamivudine Lamivudine Ritonavir may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole Riluzole Ritonavir may decrease the excretion rate of Riluzole which could result in a higher serum level.
Acarbose Acarbose The therapeutic efficacy of Acarbose can be decreased when used in combination with Ritonavir.
Glimepiride Glimepiride The therapeutic efficacy of Glimepiride can be decreased when used in combination with Ritonavir.
Anastrozole Anastrozole The metabolism of Anastrozole can be decreased when combined with Ritonavir.
Gemcitabine Injection Gemcitabine Injection The serum concentration of Gemcitabine can be increased when it is combined with Ritonavir.
Indinavir Indinavir The serum concentration of Indinavir can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The serum concentration of Docetaxel can be increased when it is combined with Ritonavir.
Clomipramine Clomipramine The serum concentration of Clomipramine can be increased when it is combined with Ritonavir.
Zafirlukast Zafirlukast The serum concentration of Zafirlukast can be increased when it is combined with Ritonavir.
Mirtazapine Mirtazapine The serum concentration of Mirtazapine can be increased when it is combined with Ritonavir.
Zileuton Zileuton The serum concentration of Zileuton can be increased when it is combined with Ritonavir.
Valsartan Valsartan The excretion of Valsartan can be decreased when combined with Ritonavir.
Insulin Lispro Injection Insulin Lispro Injection The therapeutic efficacy of Insulin lispro can be decreased when used in combination with Ritonavir.
Donepezil Donepezil The serum concentration of Donepezil can be increased when it is combined with Ritonavir.
Nelfinavir Nelfinavir The serum concentration of Ritonavir can be increased when it is combined with Nelfinavir.
Fexofenadine Fexofenadine The serum concentration of Fexofenadine can be increased when it is combined with Ritonavir.
Azithromycin Azithromycin The serum concentration of Azithromycin can be increased when it is combined with Ritonavir.
Loratadine Loratadine The serum concentration of Ritonavir can be increased when it is combined with Loratadine.
Carvedilol Carvedilol The serum concentration of Carvedilol can be increased when it is combined with Ritonavir.
Flutamide Flutamide The serum concentration of Flutamide can be increased when it is combined with Ritonavir.
Selegiline Selegiline The serum concentration of Selegiline can be increased when it is combined with Ritonavir.
Bicalutamide Bicalutamide The serum concentration of Ritonavir can be increased when it is combined with Bicalutamide.
Sertraline Sertraline The serum concentration of Sertraline can be increased when it is combined with Ritonavir.
Propafenone Propafenone The serum concentration of Propafenone can be increased when it is combined with Ritonavir.
Letrozole Letrozole The serum concentration of Letrozole can be increased when it is combined with Ritonavir.
Raloxifene Raloxifene Ritonavir may decrease the excretion rate of Raloxifene which could result in a higher serum level.
Irbesartan Irbesartan The metabolism of Irbesartan can be decreased when combined with Ritonavir.
Tamsulosin Tamsulosin The serum concentration of Tamsulosin can be increased when it is combined with Ritonavir.
Ropinirole Ropinirole The metabolism of Ropinirole can be increased when combined with Ritonavir.
Finasteride Finasteride The serum concentration of Finasteride can be increased when it is combined with Ritonavir.
Quetiapine Quetiapine The serum concentration of Quetiapine can be increased when it is combined with Ritonavir.
Cetirizine Cetirizine The risk or severity of QTc prolongation can be increased when Cetirizine is combined with Ritonavir.
Paroxetine Paroxetine The serum concentration of Paroxetine can be increased when it is combined with Ritonavir.
Citalopram Citalopram Ritonavir may increase the QTc-prolonging activities of Citalopram.
Capecitabine Capecitabine The metabolism of Capecitabine can be increased when combined with Ritonavir.
Efavirenz Efavirenz The risk or severity of adverse effects can be increased when Efavirenz is combined with Ritonavir.
Abacavir Abacavir The serum concentration of Abacavir can be decreased when it is combined with Ritonavir.
Sildenafil Sildenafil The serum concentration of Sildenafil can be increased when it is combined with Ritonavir.
Pioglitazone Pioglitazone The serum concentration of Pioglitazone can be increased when it is combined with Ritonavir.
Celecoxib Celecoxib The serum concentration of Celecoxib can be increased when it is combined with Ritonavir.
Rosiglitazone Rosiglitazone The serum concentration of Rosiglitazone can be increased when it is combined with Ritonavir.
Tolterodine Tolterodine The serum concentration of Tolterodine can be increased when it is combined with Ritonavir.
Thalidomide Thalidomide The metabolism of Ritonavir can be increased when combined with Thalidomide.
Aluminum Hydroxide Aluminum Hydroxide Aluminum hydroxide can cause a decrease in the absorption of Ritonavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nateglinide Nateglinide The serum concentration of Nateglinide can be increased when it is combined with Ritonavir.
Galantamine Galantamine The serum concentration of Galantamine can be increased when it is combined with Ritonavir.
Rabeprazole Rabeprazole The serum concentration of Rabeprazole can be increased when it is combined with Ritonavir.
Terbinafine Terbinafine The serum concentration of Terbinafine can be increased when it is combined with Ritonavir.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists